Inhibition of Chk1 stimulates cytotoxic action of platinum-based drugs and TRAIL combination in human prostate cancer cells
Krkoška, Martin, Paruch, Kamil, Šošolíková, Tereza, Vázquez-Gómez, Gerardo, Herůdková, Jarmila, Novotný, Jan, Ovesná, Petra, Sova, Petr, Hyršlová Vaculová, Alena
Published in Biological chemistry (25.06.2024)
Published in Biological chemistry (25.06.2024)
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Cisplatin or LA-12 enhance killing effects of TRAIL in prostate cancer cells through Bid-dependent stimulation of mitochondrial apoptotic pathway but not caspase-10
Vondálová Blanářová, Olga, Šafaříková, Barbora, Herůdková, Jarmila, Krkoška, Martin, Tománková, Silvie, Kahounová, Zuzana, Anděra, Ladislav, Bouchal, Jan, Kharaishvili, Gvantsa, Král, Milan, Sova, Petr, Kozubík, Alois, Hyršlová Vaculová, Alena
Published in PloS one (28.11.2017)
Published in PloS one (28.11.2017)
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DHA-mediated enhancement of TRAIL-induced apoptosis in colon cancer cells is associated with engagement of mitochondria and specific alterations in sphingolipid metabolism
Skender, Belma, Hofmanová, Jiřina, Slavík, Josef, Jelínková, Iva, Machala, Miroslav, Moyer, Mary Pat, Kozubík, Alois, Hyršlová Vaculová, Alena
Published in Biochimica et biophysica acta (01.09.2014)
Published in Biochimica et biophysica acta (01.09.2014)
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Loss of PTEN Facilitates Rosiglitazone-Mediated Enhancement of Platinum(IV) Complex LA-12-Induced Apoptosis in Colon Cancer Cells
Lauková, Jarmila, Kozubík, Alois, Hofmanová, Jiřina, Nekvindová, Jana, Sova, Petr, Moyer, Mary Pat, Ehrmann, Jiří, Hyršlová Vaculová, Alena
Published in PloS one (22.10.2015)
Published in PloS one (22.10.2015)
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Interaction of Dietary Fatty Acids with Tumour Necrosis Factor Family Cytokines during Colon Inflammation and Cancer
Hofmanova, Jirina, Strakova, Nicol, Vaculova, Alena Hyrslova, Tylichova, Zuzana, Safarikova, Barbora, Skender, Belma, Kozubik, Alois
Published in Mediators of Inflammation (01.01.2014)
Published in Mediators of Inflammation (01.01.2014)
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Dietary fatty acids specifically modulate phospholipid pattern in colon cells with distinct differentiation capacities
Hofmanová, Jiřina, Slavík, Josef, Ovesná, Petra, Tylichová, Zuzana, Vondráček, Jan, Straková, Nicol, Vaculová, Alena Hyršlová, Ciganek, Miroslav, Kozubík, Alois, Knopfová, Lucie, Šmarda, Jan, Machala, Miroslav
Published in European journal of nutrition (01.06.2017)
Published in European journal of nutrition (01.06.2017)
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Platinum(IV) complex LA-12 exerts higher ability than cisplatin to enhance TRAIL-induced cancer cell apoptosis via stimulation of mitochondrial pathway
Jelínková, Iva, Šafaříková, Barbora, Vondálová Blanářová, Olga, Skender, Belma, Hofmanová, Jiřina, Sova, Petr, Moyer, Mary Pat, Kozubík, Alois, Kolář, Zdeněk, Ehrmann, Jiří, Hyršlová Vaculová, Alena
Published in Biochemical pharmacology (01.12.2014)
Published in Biochemical pharmacology (01.12.2014)
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Activation of autophagy and PPARγ protect colon cancer cells against apoptosis induced by interactive effects of butyrate and DHA in a cell type-dependent manner: The role of cell differentiation
Tylichová, Zuzana, Straková, Nicol, Vondráček, Jan, Vaculová, Alena Hyršlová, Kozubík, Alois, Hofmanová, Jiřina
Published in The Journal of nutritional biochemistry (01.01.2017)
Published in The Journal of nutritional biochemistry (01.01.2017)
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Deregulation of signaling pathways controlling cell survival and proliferation in cancer cells alters induction of cytochrome P450 family 1 enzymes
Krkoška, Martin, Svobodová, Jana, Kabátková, Markéta, Zapletal, Ondřej, Hyršlová Vaculová, Alena, Nekvindová, Jana, Vondráček, Jan
Published in Toxicology (Amsterdam) (01.09.2021)
Published in Toxicology (Amsterdam) (01.09.2021)
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Role of miR-653 and miR-29c in downregulation of CYP1A2 expression in hepatocellular carcinoma
Krkoška, Martin, Nekvindová, Jana, Nevědělová, Kateřina, Zubáňová, Veronika, Radová, Lenka, Vondráček, Jan, Herůdková, Jarmila, Slabý, Ondřej, Kiss, Igor, Bohovicová, Lucia, Fabian, Pavel, Tylichová, Zuzana, Kala, Zdeněk, Kysela, Petr, Ostřížková, Lenka, Palička, Vladimír, Hyršlová Vaculová, Alena
Published in Pharmacological reports (01.02.2022)
Published in Pharmacological reports (01.02.2022)
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Phospholipid profiling enables to discriminate tumor- and non-tumor-derived human colon epithelial cells: Phospholipidome similarities and differences in colon cancer cell lines and in patient-derived cell samples
Hofmanová, Jiřina, Slavík, Josef, Ovesná, Petra, Tylichová, Zuzana, Dušek, Ladislav, Straková, Nicol, Vaculová, Alena Hyršlová, Ciganek, Miroslav, Kala, Zdeněk, Jíra, Miroslav, Penka, Igor, Kyclová, Jitka, Kolář, Zdeněk, Kozubík, Alois, Machala, Miroslav, Vondráček, Jan
Published in PloS one (30.01.2020)
Published in PloS one (30.01.2020)
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Docosahexaenoic fatty acid (DHA) in the regulation of colon cell growth and cell death: a review
Skender, Belma, Vaculova, Alena Hyrslova, Hofmanova, Jirina
Published in Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia (01.09.2012)
Published in Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia (01.09.2012)
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Hepatocellular carcinoma: Gene expression profiling and regulation of xenobiotic-metabolizing cytochromes P450
Nekvindova, Jana, Mrkvicova, Alena, Zubanova, Veronika, Hyrslova Vaculova, Alena, Anzenbacher, Pavel, Soucek, Pavel, Radova, Lenka, Slaby, Ondrej, Kiss, Igor, Vondracek, Jan, Spicakova, Alena, Bohovicova, Lucia, Fabian, Pavel, Kala, Zdenek, Palicka, Vladimir
Published in Biochemical pharmacology (01.07.2020)
Published in Biochemical pharmacology (01.07.2020)
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Inhibition of vacuolar ATPase attenuates the TRAIL‐induced activation of caspase‐8 and modulates the trafficking of TRAIL receptosomes
Horova, Vladimira, Hradilova, Nada, Jelinkova, Iva, Koc, Michal, Svadlenka, Jan, Brazina, Jan, Klima, Martin, Slavik, Josef, Hyrslova Vaculova, Alena, Andera, Ladislav
Published in The FEBS journal (01.07.2013)
Published in The FEBS journal (01.07.2013)
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Correction: 5-Fluorouracil-induced RNA stress engages a TRAIL-DISC-dependent apoptosis axis facilitated by p53
Akpinar, Birce, Bracht, Ethiene V, Reijnders, Dorin, Safarikova, Barbora, Jelinkova, Iva, Grandien, Alf, Vaculova, Alena Hyrslova, Zhivotovsky, Boris, Olsson, Magnus
Published in Oncotarget (01.11.2016)
Published in Oncotarget (01.11.2016)
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Journal Article
Correction: 5-Fluorouracil-induced RNA stress engages a TRAIL-DISC-dependent apoptosis axis facilitated by p53
Akpinar, Birce, Bracht, Ethiene V, Reijnders, Dorin, Safarikova, Barbora, Jelinkova, Iva, Grandien, Alf, Hyrslova Vaculova, Alena, Zhivotovsky, Boris, Olsson, Magnus
Published in Oncotarget (10.05.2016)
Published in Oncotarget (10.05.2016)
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Journal Article
Loss of PTEN Facilitates Rosiglitazone-Mediated Enhancement of Platinum
Lauková, Jarmila, Kozubík, Alois, Hofmanová, Jirina, Nekvindová, Jana, Sova, Petr, Moyer, Mary Pat, Ehrmann, Jirí, Hyrslová Vaculová, Alena
Published in PloS one (22.10.2015)
Published in PloS one (22.10.2015)
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Journal Article
5-Fluorouracil-induced RNA stress engages a TRAIL-DISC-dependent apoptosis axis facilitated by p53
Akpinar, Birce, Bracht, Ethiene V, Reijnders, Dorin, Safarikova, Barbora, Jelinkova, Iva, Grandien, Alf, Vaculova, Alena Hyrslova, Zhivotovsky, Boris, Olsson, Magnus
Published in Oncotarget (22.12.2015)
Published in Oncotarget (22.12.2015)
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