A Novel Polymyxin Derivative That Lacks the Fatty Acid Tail and Carries Only Three Positive Charges Has Strong Synergism with Agents Excluded by the Intact Outer Membrane
VAARA, Martti, SIIKANEN, Osmo, APAJALAHTI, Juha, FOX, John, FRIMODT-MØLLER, Niels, HUI HE, POUDYAL, Anima, JIAN LI, NATION, Roger L, VAARA, Timo
Published in Antimicrobial Agents and Chemotherapy (01.08.2010)
Published in Antimicrobial Agents and Chemotherapy (01.08.2010)
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Human kidney on a chip assessment of polymyxin antibiotic nephrotoxicity
Weber, Elijah J, Lidberg, Kevin A, Wang, Lu, Bammler, Theo K, MacDonald, James W, Li, Mavis J, Redhair, Michelle, Atkins, William M, Tran, Cecilia, Hines, Kelly M, Herron, Josi, Xu, Libin, Monteiro, Maria Beatriz, Ramm, Susanne, Vaidya, Vishal, Vaara, Martti, Vaara, Timo, Himmelfarb, Jonathan, Kelly, Edward J
Published in JCI insight (20.12.2018)
Published in JCI insight (20.12.2018)
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Novel Polymyxin Derivatives Carrying Only Three Positive Charges Are Effective Antibacterial Agents
VAARA, Martti, FOX, John, LOIDL, Günther, SIIKANEN, Osmo, APAJALAHTI, Juha, HANSEN, Frank, FRIMODT-MØLLER, Niels, NAGAI, Junva, TAKANO, Mikihisa, VAARA, Timo
Published in Antimicrobial Agents and Chemotherapy (01.09.2008)
Published in Antimicrobial Agents and Chemotherapy (01.09.2008)
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Excretion of the Polymyxin Derivative NAB739 in Murine Urine
Vaara, Martti, Vaara, Timo, Kuka, Janis, Sevostjanovs, Eduards, Grinberga, Solveiga, Dambrova, Maija, Liepinsh, Edgars
Published in Antibiotics (Basel) (27.03.2020)
Published in Antibiotics (Basel) (27.03.2020)
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The polymyxin derivative NAB739 is synergistic with several antibiotics against polymyxin-resistant strains of Escherichia coli, Klebsiella pneumoniae and Acinetobacter baumannii
Tyrrell, Jonathan M., Aboklaish, Ali F., Walsh, Timothy R., Vaara, Timo, Vaara, Martti
Published in Peptides (New York, N.Y. : 1980) (01.02.2019)
Published in Peptides (New York, N.Y. : 1980) (01.02.2019)
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Susceptibility of carbapenemase-producing strains of Klebsiella pneumoniae and Escherichia coli to the direct antibacterial activity of NAB739 and to the synergistic activity of NAB7061 with rifampicin and clarithromycin
Vaara, Martti, Siikanen, Osmo, Apajalahti, Juha, Frimodt-Møller, Niels, Vaara, Timo
Published in Journal of antimicrobial chemotherapy (01.05.2010)
Published in Journal of antimicrobial chemotherapy (01.05.2010)
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Pharmacokinetics of novel antimicrobial cationic peptides NAB 7061 and NAB 739 in rats following intravenous administration
Ali, Feda' Emad Atta, Cao, Guoying, Poudyal, Anima, Vaara, Timo, Nation, Roger L., Vaara, Martti, Li, Jian
Published in Journal of antimicrobial chemotherapy (01.11.2009)
Published in Journal of antimicrobial chemotherapy (01.11.2009)
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