Mouse models of nonalcoholic steatohepatitis in preclinical drug development
Hansen, Henrik H., Feigh, Michael, Veidal, Sanne S., Rigbolt, Kristoffer T., Vrang, Niels, Fosgerau, Keld
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Published in Drug discovery today (01.11.2017)
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Metabolic and gut microbiome changes following GLP-1 or dual GLP-1/GLP-2 receptor agonist treatment in diet-induced obese mice
Madsen, Mette Simone Aae, Holm, Jacob Bak, Pallejà, Albert, Wismann, Pernille, Fabricius, Katrine, Rigbolt, Kristoffer, Mikkelsen, Martin, Sommer, Morten, Jelsing, Jacob, Nielsen, Henrik Bjørn, Vrang, Niels, Hansen, Henrik H
Published in Scientific reports (30.10.2019)
Published in Scientific reports (30.10.2019)
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Expression and Distribution of Glucagon-Like Peptide-1 Receptor mRNA, Protein and Binding in the Male Nonhuman Primate (Macaca mulatta) Brain
Heppner, Kristy M, Kirigiti, Melissa, Secher, Anna, Paulsen, Sarah Juel, Buckingham, Rikley, Pyke, Charles, Knudsen, Lotte B, Vrang, Niels, Grove, Kevin L
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Metabolic and hepatic effects of liraglutide, obeticholic acid and elafibranor in diet-induced obese mouse models of biopsy-confirmed nonalcoholic steatohepatitis
Tølbøl, Kirstine S, Kristiansen, Maria Nb, Hansen, Henrik H, Veidal, Sanne S, Rigbolt, Kristoffer Tg, Gillum, Matthew P, Jelsing, Jacob, Vrang, Niels, Feigh, Michael
Published in World journal of gastroenterology : WJG (14.01.2018)
Published in World journal of gastroenterology : WJG (14.01.2018)
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The GLP-1 receptor agonist liraglutide reduces pathology-specific tau phosphorylation and improves motor function in a transgenic hTauP301L mouse model of tauopathy
Hansen, Henrik H, Barkholt, Pernille, Fabricius, Katrine, Jelsing, Jacob, Terwel, Dick, Pyke, Charles, Knudsen, Lotte Bjerre, Vrang, Niels
Published in Brain research (01.03.2016)
Published in Brain research (01.03.2016)
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The GLP-1 Receptor Agonist Liraglutide Improves Memory Function and Increases Hippocampal CA1 Neuronal Numbers in a Senescence-Accelerated Mouse Model of Alzheimer's Disease
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Published in Journal of Alzheimer's disease (26.06.2015)
Published in Journal of Alzheimer's disease (26.06.2015)
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Characterization of combined linagliptin and Y2R agonist treatment in diet-induced obese mice
Hansen, Henrik H, Grønlund, Rikke V, Baader-Pagler, Tamara, Haebel, Peter, Tammen, Harald, Larsen, Leif Kongskov, Jelsing, Jacob, Vrang, Niels, Klein, Thomas
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Towards a standard diet-induced and biopsy-confirmed mouse model of non-alcoholic steatohepatitis: Impact of dietary fat source
Boland, Michelle L, Oró, Denise, Tølbøl, Kirstine S, Thrane, Sebastian T, Nielsen, Jens Christian, Cohen, Taylor S, Tabor, David E, Fernandes, Fiona, Tovchigrechko, Andrey, Veidal, Sanne S, Warrener, Paul, Sellman, Bret R, Jelsing, Jacob, Feigh, Michael, Vrang, Niels, Trevaskis, James L, Hansen, Henrik H
Published in World journal of gastroenterology : WJG (07.09.2019)
Published in World journal of gastroenterology : WJG (07.09.2019)
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Multi-omics characterization of a diet-induced obese model of non-alcoholic steatohepatitis
Ægidius, Helene M, Veidal, Sanne S, Feigh, Michael, Hallenborg, Philip, Puglia, Michele, Pers, Tune H, Vrang, Niels, Jelsing, Jacob, Kornum, Birgitte R, Blagoev, Blagoy, Rigbolt, Kristoffer T G
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Published in Scientific reports (24.01.2020)
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Therapeutic effects of lisinopril and empagliflozin in a mouse model of hypertension-accelerated diabetic kidney disease
Østergaard, Mette V., Secher, Thomas, Christensen, Michael, Salinas, Casper Gravesen, Roostalu, Urmas, Skytte, Jacob Lercke, Rune, Ida, Hansen, Henrik H., Jelsing, Jacob, Vrang, Niels, Fink, Lisbeth N.
Published in American journal of physiology. Renal physiology (01.08.2021)
Published in American journal of physiology. Renal physiology (01.08.2021)
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Lipidated PrRP31 metabolites are long acting dual GPR10 and NPFF2 receptor agonists with potent body weight lowering effect
Alexopoulou, Flora, Bech, Esben Matzen, Pedersen, Søren Ljungberg, Thorbek, Ditte Dencker, Leurs, Ulrike, Rudkjær, Lise Christine Biehl, Fosgerau, Keld, Hansen, Henrik H, Vrang, Niels, Jelsing, Jacob, Elster, Lisbeth
Published in Scientific reports (01.02.2022)
Published in Scientific reports (01.02.2022)
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Human translatability of the GAN diet-induced obese mouse model of non-alcoholic steatohepatitis
Hansen, Henrik H, Ægidius, Helene M, Oró, Denise, Evers, Simon S, Heebøll, Sara, Eriksen, Peter Lykke, Thomsen, Karen Louise, Bengtsson, Anja, Veidal, Sanne S, Feigh, Michel, Suppli, Malte P, Knop, Filip K, Grønbæk, Henning, Miranda, Diego, Trevaskis, James L, Vrang, Niels, Jelsing, Jacob, Rigbolt, Kristoffer T G
Published in BMC gastroenterology (06.07.2020)
Published in BMC gastroenterology (06.07.2020)
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Effect of captopril on post-infarction remodelling visualized by light sheet microscopy and echocardiography
Roostalu, Urmas, Thisted, Louise, Skytte, Jacob Lercke, Salinas, Casper Gravesen, Pedersen, Philip Juhl, Hecksher-Sørensen, Jacob, Rolin, Bidda, Hansen, Henrik H, MacKrell, James G, Christie, Robert M, Vrang, Niels, Jelsing, Jacob, Zois, Nora Elisabeth
Published in Scientific reports (04.03.2021)
Published in Scientific reports (04.03.2021)
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Characterisation of age-dependent beta cell dynamics in the male db/db mice
Dalbøge, Louise S, Almholt, Dorthe L C, Neerup, Trine S R, Vassiliadis, Efstathios, Vrang, Niels, Pedersen, Lars, Fosgerau, Keld, Jelsing, Jacob
Published in PloS one (06.12.2013)
Published in PloS one (06.12.2013)
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Obese diet-induced mouse models of nonalcoholic steatohepatitis-tracking disease by liver biopsy
Kristiansen, Maria Nicoline Baandrup, Veidal, Sanne Skovgård, Rigbolt, Kristoffer Tobias Gustav, Tølbøl, Kirstine Sloth, Roth, Jonathan David, Jelsing, Jacob, Vrang, Niels, Feigh, Michael
Published in World journal of hepatology (08.06.2016)
Published in World journal of hepatology (08.06.2016)
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Long-Term Treatment with Liraglutide, a Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist, Has No Effect on β-Amyloid Plaque Load in Two Transgenic APP/PS1 Mouse Models of Alzheimer's Disease
Hansen, Henrik H, Fabricius, Katrine, Barkholt, Pernille, Kongsbak-Wismann, Pernille, Schlumberger, Chantal, Jelsing, Jacob, Terwel, Dick, Termont, Annelies, Pyke, Charles, Knudsen, Lotte Bjerre, Vrang, Niels
Published in PloS one (15.07.2016)
Published in PloS one (15.07.2016)
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Hepatoprotective effects of semaglutide, lanifibranor and dietary intervention in the GAN diet‐induced obese and biopsy‐confirmed mouse model of NASH
Møllerhøj, Mathias B., Veidal, Sanne S., Thrane, Kirstine Tølbøl, Oró, Denise, Overgaard, Agnete, Salinas, Casper Gravesen, Madsen, Martin Rønn, Pfisterer, Larissa, Vyberg, Mogens, Simon, Eric, Broermann, Andre, Vrang, Niels, Jelsing, Jacob, Feigh, Michael, Hansen, Henrik H.
Published in Clinical and translational science (01.05.2022)
Published in Clinical and translational science (01.05.2022)
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A Hamster Model of Diet-Induced Obesity for Preclinical Evaluation of Anti-Obesity, Anti-Diabetic and Lipid Modulating Agents
Dalbøge, Louise S, Pedersen, Philip J, Hansen, Gitte, Fabricius, Katrine, Hansen, Henrik B, Jelsing, Jacob, Vrang, Niels
Published in PloS one (12.08.2015)
Published in PloS one (12.08.2015)
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