Editorial: Translation of genetically engineered T cells in cancer immunotherapy
Voss, Ralf-Holger, Echchannaoui, Hakim, Huang, He, Xue, Shao-An
Published in Frontiers in immunology (07.09.2023)
Published in Frontiers in immunology (07.09.2023)
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Journal Article
CRISPR/Cas9-mediated TGFβRII disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells in vitro
Alishah, Khadijeh, Birtel, Matthias, Masoumi, Elham, Jafarzadeh, Leila, Mirzaee, Hamid Reza, Hadjati, Jamshid, Voss, Ralf-Holger, Diken, Mustafa, Asad, Sedighe
Published in Journal of translational medicine (27.11.2021)
Published in Journal of translational medicine (27.11.2021)
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Journal Article
A Potent Tumor-Reactive p53-Specific Single-Chain TCR without On- or Off-Target Autoimmunity In Vivo
Echchannaoui, Hakim, Petschenka, Jutta, Ferreira, Edite Antunes, Hauptrock, Beate, Lotz-Jenne, Carina, Voss, Ralf-Holger, Theobald, Matthias
Published in Molecular therapy (02.01.2019)
Published in Molecular therapy (02.01.2019)
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Journal Article
Enhancing the expression and function of an EBV-TCR on engineered T cells by combining Sc-TCR design with CRISPR editing to prevent mispairing
Xue, Shao-An, Chen, Yuan, Voss, Ralf-Holger, Kisan, Virad, Wang, Bo, Chen, Ke-Ke, He, Feng-Qin, Cheng, Xiao-Xia, Scolamiero, Laura, Holler, Angelika, Gao, Liquan, Morris, Emma, Stauss, Hans J
Published in Cellular & molecular immunology (01.12.2020)
Published in Cellular & molecular immunology (01.12.2020)
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Journal Article
Cytotoxicity of tumor antigen specific human T cells is unimpaired by arginine depletion
Munder, Markus, Engelhardt, Melanie, Knies, Diana, Medenhoff, Sergej, Wabnitz, Guido, Luckner-Minden, Claudia, Feldmeyer, Nadja, Voss, Ralf-Holger, Kropf, Pascale, Müller, Ingrid, Conradi, Roland, Samstag, Yvonne, Theobald, Matthias, Ho, Anthony D, Goldschmidt, Hartmut, Hundemer, Michael
Published in PloS one (23.05.2013)
Published in PloS one (23.05.2013)
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Journal Article
Circumventing tolerance to a human MDM2-derived tumor antigen by TCR gene transfer
Theobald, Matthias, Stanislawski, Thomas, Voss, Ralf-Holger, Lotz, Carina, Sadovnikova, Elena, Willemsen, Ralph A, Kuball, Jürgen, Ruppert, Thomas, Bolhuis, Reinder L. H, Melief, Cornelius J, Huber, Christoph, Stauss, Hans J
Published in Nature immunology (01.10.2001)
Published in Nature immunology (01.10.2001)
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Journal Article
Development of a Wilms’ tumor antigen-specific T-cell receptor for clinical trials: engineered patient’s T cells can eliminate autologous leukemia blasts in NOD/SCID mice
XUE, Shao-An, LIQUAN GAO, THOMAS, Sharyn, HART, Daniel P, ZHAO XUE, John, GILLMORE, Roopinder, VOSS, Ralf-Holger, MORRIS, Emma, STAUSS, Hans J
Published in Haematologica (Roma) (01.01.2010)
Published in Haematologica (Roma) (01.01.2010)
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Journal Article
Low-Dose Irradiation Programs Macrophage Differentiation to an iNOS+/M1 Phenotype that Orchestrates Effective T Cell Immunotherapy
Klug, Felix, Prakash, Hridayesh, Huber, Peter E., Seibel, Tobias, Bender, Noemi, Halama, Niels, Pfirschke, Christina, Voss, Ralf Holger, Timke, Carmen, Umansky, Ludmila, Klapproth, Kay, Schäkel, Knut, Garbi, Natalio, Jäger, Dirk, Weitz, Jürgen, Schmitz-Winnenthal, Hubertus, Hämmerling, Günter J., Beckhove, Philipp
Published in Cancer cell (11.11.2013)
Published in Cancer cell (11.11.2013)
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Journal Article
Facilitating matched pairing and expression of TCR chains introduced into human T cells
Kuball, Jürgen, Dossett, Michelle L., Wolfl, Matthias, Ho, William Y., Voss, Ralf-Holger, Fowler, Carla, Greenberg, Philip D.
Published in Blood (15.03.2007)
Published in Blood (15.03.2007)
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Journal Article
Increasing functional avidity of TCR-redirected T cells by removing defined N-glycosylation sites in the TCR constant domain
Kuball, Jürgen, Hauptrock, Beate, Malina, Victoria, Antunes, Edite, Voss, Ralf-Holger, Wolfl, Matthias, Strong, Roland, Theobald, Matthias, Greenberg, Philip D
Published in The Journal of experimental medicine (16.02.2009)
Published in The Journal of experimental medicine (16.02.2009)
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Journal Article
An optimized single chain TCR scaffold relying on the assembly with the native CD3-complex prevents residual mispairing with endogenous TCRs in human T-cells
Knies, Diana, Klobuch, Sebastian, Xue, Shao-An, Birtel, Matthias, Echchannaoui, Hakim, Yildiz, Oezlem, Omokoko, Tana, Guillaume, Philippe, Romero, Pedro, Stauss, Hans, Sahin, Ugur, Herr, Wolfgang, Theobald, Matthias, Thomas, Simone, Voss, Ralf-Holger
Published in Oncotarget (19.04.2016)
Published in Oncotarget (19.04.2016)
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Journal Article
Molecular Design of the Cαβ Interface Favors Specific Pairing of Introduced TCRαβ in Human T Cells
Voss, Ralf-Holger, Willemsen, Ralph A., Kuball, Jürgen, Grabowski, Margarete, Engel, Renate, Intan, Ratna S., Guillaume, Philippe, Romero, Pedro, Huber, Christoph, Theobald, Matthias
Published in The Journal of immunology (1950) (01.01.2008)
Published in The Journal of immunology (1950) (01.01.2008)
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Journal Article
Coexpression of the T-cell receptor constant α domain triggers tumor reactivity of single-chain TCR-transduced human T cells
Voss, Ralf-Holger, Thomas, Simone, Pfirschke, Christina, Hauptrock, Beate, Klobuch, Sebastian, Kuball, Jürgen, Grabowski, Margarete, Engel, Renate, Guillaume, Philippe, Romero, Pedro, Huber, Christoph, Beckhove, Philipp, Theobald, Matthias
Published in Blood (24.06.2010)
Published in Blood (24.06.2010)
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Journal Article
Cooperation of Human Tumor-Reactive CD4 + and CD8 + T Cells after Redirection of Their Specificity by a High-Affinity p53A2.1-Specific TCR
Kuball, Jürgen, Schmitz, Frank W., Voss, Ralf-Holger, Ferreira, Edite Antunes, Engel, Renate, Guillaume, Philippe, Strand, Susanne, Romero, Pedro, Huber, Christoph, Sherman, Linda A., Theobald, Matthias
Published in Immunity (Cambridge, Mass.) (2005)
Published in Immunity (Cambridge, Mass.) (2005)
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Journal Article
CIMT 2016: Mechanisms of efficacy in cancer immunotherapy - Report on the 14th Annual Meeting of the Association for Cancer Immunotherapy May 10-12 2016, Mainz, Germany
Kranz, Lena M, Birtel, Matthias, Hilscher, Lina, Grunwitz, Christian, Petschenka, Jutta, Vascotto, Fulvia, Vormehr, Mathias, Voss, Ralf-Holger, Kreiter, Sebastian, Diken, Mustafa
Published in Human vaccines & immunotherapeutics (01.11.2016)
Published in Human vaccines & immunotherapeutics (01.11.2016)
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Journal Article
Conference Proceeding
Redirection of T Cells by Delivering a Transgenic Mouse-Derived MDM2 Tumor Antigen-Specific TCR and its Humanized Derviative Is Governed by the CD8 Coreceptor and Affects Natural Human TCR Expression
Voss, Ralf-Holger, Kuball, Jürgen, Engel, Renate, Guillaume, Philippe, Romero, Pedro, Huber, Christoph, Theobald, Matthias
Published in Immunologic research (2006)
Published in Immunologic research (2006)
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Journal Article
Designing TCR for cancer immunotherapy
Voss, Ralf-Holger, Kuball, Jürgen, Theobald, Matthias
Published in Methods in molecular medicine (2005)
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Published in Methods in molecular medicine (2005)
Journal Article
항원 수용체 및 이의 용도
VOSS RALF HOLGER, SIMON PETRA, BIRTEL MATTHIAS, CASPAR JANINA, SAHIN UGUR
Year of Publication 18.11.2019
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Year of Publication 18.11.2019
Patent
Changing viral tropism using immunoliposomes alters the stability of gene expression: implications for viral vector design
Tan, Peng H, Xue, Shao-An, Wei, Bin, Holler, Angelika, Voss, Ralf-Holger, George, Andrew J T
Published in Molecular medicine (Cambridge, Mass.) (01.03.2007)
Published in Molecular medicine (Cambridge, Mass.) (01.03.2007)
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Journal Article
항원 수용체 및 그의 용도
THEOBALD MATTHIAS, VOSS RALF HOLGER, SIMON PETRA, BIRTEL MATTHIAS, SAHIN UGUR
Year of Publication 30.05.2018
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Year of Publication 30.05.2018
Patent