S1057 A Randomized Phase I Study Comparing Pharmacokinetics, Safety and Immunogenicity of High Concentration Formulation (100 mg/mL) With GP2017 Formulation (50 mg/mL), an Adalimumab Biosimilar, in Healthy Male Subjects
Rondon, Juan Carlos, Von Richter, Oliver, Fey, Constanze, Fan, Jamie, Furlan, Fabricio, Lemke, Lena
Published in The American journal of gastroenterology (01.10.2022)
Published in The American journal of gastroenterology (01.10.2022)
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Journal Article
Signal-to-noise ratio to assess magnitude, kinetics and impact on pharmacokinetics of the immune response to an adalimumab biosimilar
Guerrieri, Davide, Horvat, Matej, Fan, Jamie, Wang, Jessie, Lemke, Lena, Richter, Oliver von, Poetzl, Johann
Published in Bioanalysis (01.01.2024)
Published in Bioanalysis (01.01.2024)
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Journal Article
Pharmacokinetics and Safety of Letermovir Coadministered With Cyclosporine A or Tacrolimus in Healthy Subjects
Kropeit, Dirk, Richter, Oliver, Stobernack, Hans‐Peter, Rübsamen‐Schaeff, Helga, Zimmermann, Holger
Published in Clinical pharmacology in drug development (01.01.2018)
Published in Clinical pharmacology in drug development (01.01.2018)
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First‐in‐Human, Single‐ and Multiple‐Ascending‐Dose, Food‐Effect, and Absolute Bioavailability Trials to Assess the Pharmacokinetics, Safety, and Tolerability of Pritelivir, a Nonnucleoside Helicase‐Primase Inhibitor Against Herpes Simplex Virus in Healthy Subjects
Kropeit, Dirk, Bonsmann, Susanne, Richter, Oliver, McCormick, David, Pausch, Jörg, Sumner, Melanie, Birkmann, Alexander, Zimmermann, Holger, Rübsamen‐Schaeff, Helga
Published in Clinical pharmacology in drug development (01.07.2023)
Published in Clinical pharmacology in drug development (01.07.2023)
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Journal Article
Cytochrome P450 3A4 and P-glycoprotein expression in human small intestinal enterocytes and hepatocytes: a comparative analysis in paired tissue specimens
von Richter, Oliver, Burk, Oliver, Fromm, Martin F, Thon, Klaus P, Eichelbaum, Michel, Kivistö, Kari T
Published in Clinical pharmacology and therapeutics (01.03.2004)
Published in Clinical pharmacology and therapeutics (01.03.2004)
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Journal Article
The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin
Greiner, B, Eichelbaum, M, Fritz, P, Kreichgauer, H P, von Richter, O, Zundler, J, Kroemer, H K
Published in The Journal of clinical investigation (15.07.1999)
Published in The Journal of clinical investigation (15.07.1999)
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Randomised, double-blind, phase III study comparing the infliximab biosimilar, PF-06438179/GP1111, with reference infliximab: efficacy, safety and immunogenicity from week 30 to week 54
Alten, Rieke, Batko, Bogdan, Hala, Tomas, Kameda, Hideto, Radominski, Sebastiao C, Tseluyko, Vira, Babic, Goran, Cronenberger, Carol, Hackley, Sarah, Rehman, Muhammad, von Richter, Oliver, Zhang, Min, Cohen, Stanley
Published in Rheumatic & musculoskeletal diseases open (01.03.2019)
Published in Rheumatic & musculoskeletal diseases open (01.03.2019)
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Journal Article
A Novel PBPK Modeling Approach to Assess Cytochrome P450 Mediated Drug‐Drug Interaction Potential of the Cytotoxic Prodrug Evofosfamide
Lüpfert, Christian, Dyroff, Martin, Richter, Oliver, Gallemann, Dieter, El Bawab, Samer, Dolgos, Hugues, Jung, Don, Hecht, Stefan, Johne, Andreas
Published in CPT: pharmacometrics and systems pharmacology (01.12.2018)
Published in CPT: pharmacometrics and systems pharmacology (01.12.2018)
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Journal Article
Effect of fluvoxamine on the pharmacokinetics of roflumilast and roflumilast N-oxide
VON RICHTER, Oliver, LAHU, Gezim, HUENNEMEYER, Andreas, HERZOG, Rolf, ZECH, Karl, HERMANN, Robert
Published in Clinical pharmacokinetics (01.01.2007)
Published in Clinical pharmacokinetics (01.01.2007)
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Tissue-specific regulation of canine intestinal and hepatic phenol and morphine UDP-glucuronosyltransferases by β-naphthoflavone in comparison with humans
Bock, Karl Walter, Bock-Hennig, Barbara S, Münzel, Peter A, Brandenburg, Jens O, Köhle, Christoph T, Soars, Matthew G, Riley, Rob J, Burchell, Brian, Richter, Oliver von, Eichelbaum, Michel F, Swedmark, Stellan, Orzechowski, Achim
Published in Biochemical pharmacology (01.05.2002)
Published in Biochemical pharmacology (01.05.2002)
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Journal Article
Characterization of the Major Metabolites of Verapamil as Substrates and Inhibitors of P-glycoprotein
Pauli-Magnus, C, von Richter, O, Burk, O, Ziegler, A, Mettang, T, Eichelbaum, M, Fromm, M F
Published in The Journal of pharmacology and experimental therapeutics (01.05.2000)
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Published in The Journal of pharmacology and experimental therapeutics (01.05.2000)
Journal Article
Identification of a Single Nucleotide Polymorphism in the TATA Box of the CYP2A6 Gene: Impairment of Its Promoter Activity
Pitarque, Marià, von Richter, Oliver, Oke, Basbug, Berkkan, Hakan, Oscarson, Mikael, Ingelman-Sundberg, Magnus
Published in Biochemical and biophysical research communications (08.06.2001)
Published in Biochemical and biophysical research communications (08.06.2001)
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ABCG2 (Breast Cancer Resistance Protein/Mitoxantrone Resistance-Associated Protein) ATPase Assay: A Useful Tool to Detect Drug-Transporter Interactions
GLAVINAS, Hristos, KIS, Emese, BATHORI, György, VON RICHTER, Oliver, KOOMEN, Gerrit-Jan, KRAJCSI, Péter, PAL, Akos, KOVACS, Rita, JANI, Marton, VAGI, Erika, MOLNAR, Eva, BANSAGHI, Szava, KELE, Zoltan, JANAKY, Tamas
Published in Drug metabolism and disposition (01.09.2007)
Published in Drug metabolism and disposition (01.09.2007)
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Journal Article
PD-0024 Phase I/II Study of Folfiri Plus the MEK1/2 Inhibitor Pimasertib (MSC1936369B) as Second-Line Treatment for KRAS Mutated Metastatic Colorectal Cancer
Macarulla, Teresa, Tabernero, Josep, Cervantes, Andrés, Roselló, Susana, Van Cutsem, Eric, Tejpar, Sabine, Prenen, Hans, Martinelli, Erika, Troiani, Teresa, Campana, Fank, Laffranchi, Bernard, Jego, Virginie, von Richter, Oliver, Ciardiello, Fortunato
Published in Annals of oncology (01.06.2012)
Published in Annals of oncology (01.06.2012)
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Journal Article
A nicotine C-oxidase gene (CYP2A6) polymorphism important for promoter activity
Pitarque, Marià, von Richter, Oliver, Rodríguez-Antona, Cristina, Wang, Jue, Oscarson, Mikael, Ingelman-Sundberg, Magnus
Published in Human mutation (01.03.2004)
Published in Human mutation (01.03.2004)
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Journal Article
Rapid and highly sensitive method for the determination of verapamil, [2H7]verapamil and metabolites in biological fluids by liquid chromatography–mass spectrometry
Richter, Oliver von, Eichelbaum, Michel, Schönberger, Frank, Hofmann, Ute
Published in Journal of chromatography. B, Biomedical sciences and applications (28.01.2000)
Published in Journal of chromatography. B, Biomedical sciences and applications (28.01.2000)
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Shed human enterocytes as a tool for the study of expression and function of intestinal drug-metabolizing enzymes and transporters
Glaeser, Hartmut, Drescher, Siegfried, van der Kuip, Heiko, Behrens, Christoph, Geick, Anke, Burk, Oliver, Dent, John, Somogyi, Andrew, Von Richter, Oliver, Griese, Ernst-Ulrich, Eichelbaum, Michel, Fromm, Martin F
Published in Clinical pharmacology and therapeutics (01.03.2002)
Published in Clinical pharmacology and therapeutics (01.03.2002)
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Journal Article
‘Totality of Evidence’ Approach in the Development of GP2017, an Approved Adalimumab Biosimilar
Gaylis, Norman, Both, Charlotte, Lemke, Lena, von Richter, Oliver, Yamauchi, Paul
Published in Advances in therapy (01.05.2024)
Published in Advances in therapy (01.05.2024)
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Journal Article
GP2017-HCF, a high concentration formulation, demonstrates similar pharmacokinetics, immunogenicity and safety to GP2017, an approved adalimumab biosimilar
von Richter, Oliver, O'Reilly, Terry, Guerrieri, Davide, Fan, Jamie, Fey, Constanze, Schussler, Steven, Furlan, Fabricio, Lemke, Lena
Published in Expert opinion on biological therapy (03.08.2023)
Published in Expert opinion on biological therapy (03.08.2023)
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