Human drug metabolism and the cytochromes P450: application and relevance of in vitro models
Venkatakrishnan, K, Von Moltke, L L, Greenblatt, D J
Published in Journal of clinical pharmacology (01.11.2001)
Published in Journal of clinical pharmacology (01.11.2001)
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IN VITRO METABOLISM OF MIDAZOLAM, TRIAZOLAM, NIFEDIPINE, AND TESTOSTERONE BY HUMAN LIVER MICROSOMES AND RECOMBINANT CYTOCHROMES P450: ROLE OF CYP3A4 AND CYP3A5
PATKI, Kiran C, VON MOLTKE, Lisa L, GREENBLATT, David J
Published in Drug metabolism and disposition (01.07.2003)
Published in Drug metabolism and disposition (01.07.2003)
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Effects of the antifungal agents on oxidative drug metabolism: Clinical relevance
VENKATAKRISHNAN, K, VON MOLTKE, L. L, GREENBLATT, D. J
Published in Clinical pharmacokinetics (01.02.2000)
Published in Clinical pharmacokinetics (01.02.2000)
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Apparent Mechanism-based Inhibition of Human CYP2D6 in Vitro by Paroxetine: Comparison with Fluoxetine and Quinidine
BERTELSEN, Kirk M, VENKATAKRISHNAN, Karthik, VON MOLTKE, Lisa L, OBACH, R. Scott, GREENBLATT, David J
Published in Drug metabolism and disposition (01.03.2003)
Published in Drug metabolism and disposition (01.03.2003)
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CYP2B6 Mediates the In Vitro Hydroxylation of Bupropion: Potential Drug Interactions with Other Antidepressants
HESSE, Leah M, VENKATAKRISHNAN, Karthik, COURT, Michael H, VON MOLTKE, Lisa L, DUAN, S. U. X, SHADER, Richard I, GREENBLATT, David J
Published in Drug metabolism and disposition (01.10.2000)
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Published in Drug metabolism and disposition (01.10.2000)
Journal Article
Interindividual Variability in Acetaminophen Glucuronidation by Human Liver Microsomes: Identification of Relevant Acetaminophen UDP-Glucuronosyltransferase Isoforms
Court, M H, Duan, S X, von Moltke, L L, Greenblatt, D J, Patten, C J, Miners, J O, Mackenzie, P I
Published in The Journal of pharmacology and experimental therapeutics (01.12.2001)
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Published in The Journal of pharmacology and experimental therapeutics (01.12.2001)
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UDP Glucuronosyltransferase (UGT) 1A6 Pharmacogenetics: II. Functional Impact of the Three Most Common Nonsynonymous UGT1A6 Polymorphisms (S7A, T181A, and R184S)
Krishnaswamy, Soundararajan, Hao, Qin, Al-Rohaimi, Abdul, Hesse, Leah M, von Moltke, Lisa L, Greenblatt, David J, Court, Michael H
Published in The Journal of pharmacology and experimental therapeutics (01.06.2005)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2005)
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Escitalopram (S-Citalopram) and Its Metabolites in Vitro: Cytochromes Mediating Biotransformation, Inhibitory Effects, and Comparison to R-Citalopram
VON MOLTKE, Lisa L, GREENBLATT, David J, GIANCARLO, Gina M, GRANDA, Brian W, HARMATZ, Jerold S, SHADER, Richard I
Published in Drug metabolism and disposition (01.08.2001)
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Published in Drug metabolism and disposition (01.08.2001)
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Comparison between Cytochrome P450 (CYP) Content and Relative Activity Approaches to Scaling from cDNA-Expressed CYPs to Human Liver Microsomes: Ratios of Accessory Proteins as Sources of Discrepancies between the Approaches
VENKATAKRISHNAN, Karthik, VON MOLTKE, Lisa L, COURT, Michael H, HARMATZ, Jerold S, CRESPI, Charles L, GREENBLATT, David J
Published in Drug metabolism and disposition (01.12.2000)
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Published in Drug metabolism and disposition (01.12.2000)
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Pharmacokinetic and pharmacodynamic interactions between zolpidem and caffeine
Cysneiros, R M, Farkas, D, Harmatz, J S, von Moltke, L L, Greenblatt, D J
Published in Clinical pharmacology and therapeutics (01.07.2007)
Published in Clinical pharmacology and therapeutics (01.07.2007)
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UDP-Glucuronosyltransferase (UGT) 2B15 Pharmacogenetics: UGT2B15 D85Y Genotype and Gender Are Major Determinants of Oxazepam Glucuronidation by Human Liver
Court, Michael H, Hao, Qin, Krishnaswamy, Soundararajan, Bekaii-Saab, Tanios, Al-Rohaimi, Abdul, von Moltke, Lisa L, Greenblatt, David J
Published in The Journal of pharmacology and experimental therapeutics (01.08.2004)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2004)
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Stereoselective Conjugation of Oxazepam by Human UDP-Glucuronosyltransferases (UGTs): S-Oxazepam Is Glucuronidated by UGT2B15, While R-Oxazepam Is Glucuronidated by UGT2B7 and UGT1A9
COURT, Michael H, DUAN, Su X, GUILLEMETTE, Chantal, JOURNAULT, Kim, KRISHNASWAMY, Soundararajan, VON MOLTKE, Lisa L, GREENBLATT, David J
Published in Drug metabolism and disposition (01.11.2002)
Published in Drug metabolism and disposition (01.11.2002)
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Journal Article
Mechanism of cytochrome P450-3A inhibition by ketoconazole
Greenblatt, David J, Zhao, Yanli, Venkatakrishnan, Karthik, Duan, Su X, Harmatz, Jerold S, Parent, Sarah J, Court, Michael H, von Moltke, Lisa L
Published in Journal of pharmacy and pharmacology (01.02.2011)
Published in Journal of pharmacy and pharmacology (01.02.2011)
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