Search Results - "VOLKOTS, DEBORAH" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Identification of Orally Active, Potent, and Selective 4-Piperazinylquinazolines as Antagonists of the Platelet-Derived Growth Factor Receptor Tyrosine Kinase Family

Identification of Orally Active, Potent, and Selective 4-Piperazinylquinazolines as Antagonists of the Platelet-Derived Growth Factor Receptor Tyrosine Kinase Family

by Pandey, Anjali, Volkots, Deborah L, Seroogy, Joseph M, Rose, Jack W, Yu, Jin-Chen, Lambing, Joseph L, Hutchaleelaha, Athiwat, Hollenbach, Stanley J, Abe, Keith, Giese, Neill A, Scarborough, Robert M
Published in Journal of medicinal chemistry (15.08.2002)

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Journal Article

Oxadiazoles as Ester Bioisosteric Replacements in Compounds Related to Disoxaril. Antirhinovirus Activity

Oxadiazoles as Ester Bioisosteric Replacements in Compounds Related to Disoxaril. Antirhinovirus Activity

by Diana, Guy D, Volkots, Deborah L, Nitz, Theodore J, Bailey, Thomas R, Long, Melody A, Vescio, Niranjan, Aldous, Suzanne, Pevear, Daniel C, Dutko, Frank J
Published in Journal of medicinal chemistry (01.07.1994)

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Journal Article

Discovery of Novel 2,8-Diazaspiro[4.5]decanes as Orally Active Glycoprotein IIb-IIIa Antagonists

Discovery of Novel 2,8-Diazaspiro[4.5]decanes as Orally Active Glycoprotein IIb-IIIa Antagonists

by Mehrotra, Mukund M., Heath, Julie A., Smyth, Mark S., Pandey, Anjali, Rose, Jack W., Seroogy, Joseph M., Volkots, Deborah L., Nannizzi-Alaimo, Lisa, Park, Gary L., Lambing, Joseph L., Hollenbach, Stanley J., Scarborough, Robert M.
Published in Journal of medicinal chemistry (08.04.2004)

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Regiospecific Synthesis of 3-Substituted 5-Alkylisoxazoles from Oxime Dianions and N-Methoxy-N-Methylalkylamides

Regiospecific Synthesis of 3-Substituted 5-Alkylisoxazoles from Oxime Dianions and N-Methoxy-N-Methylalkylamides

by Nitz, Theodore J, Volkots, Deborah L, Aldous, David J, Oglesby, Richard C
Published in Journal of organic chemistry (01.09.1994)

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Journal Article

Spirocyclic nonpeptide glycoprotein IIb-IIIa antagonists. Part 3: Synthesis and SAR of potent and specific 2,8-diazaspiro[4.5]decanes

Spirocyclic nonpeptide glycoprotein IIb-IIIa antagonists. Part 3: Synthesis and SAR of potent and specific 2,8-diazaspiro[4.5]decanes

by MEHROTRA, Mukund M, HEATH, Julie A, PANDEY, Anjali, SCARBOROUGH, Robert M, ROSE, Jack W, SMYTH, Mark S, SEROOGY, Joseph, VOLKOTS, Deborah L, RUHTER, Gerd, SCHOTTEN, Theo, ALAIMO, Lisa, PARK, Gary
Published in Bioorganic & medicinal chemistry letters (08.04.2002)

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Journal Article

Antipicornavirus activity of tetrazole analogs related to disoxaril

Antipicornavirus activity of tetrazole analogs related to disoxaril

by Diana, Guy D, Cutcliffe, David, Volkots, Deborah L, Mallamo, John P, Bailey, Thomas R, Vescio, Niranjan, Oglesby, Richard C, Nitz, Theodore J, Wetzel, Joseph
Published in Journal of medicinal chemistry (01.10.1993)

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Journal Article

Picornavirus Inhibitors: Trifluoromethyl Substitution Provides a Global Protective Effect against Hepatic Metabolism

Picornavirus Inhibitors: Trifluoromethyl Substitution Provides a Global Protective Effect against Hepatic Metabolism

by Diana, Guy D, Rudewicz, Patrick, Pevear, Daniel C, Nitz, Theodore J, Aldous, Suzanne C, Aldous, David J, Robinson, David T, Draper, Tandy, Dutko, Frank J
Published in Journal of medicinal chemistry (01.04.1995)

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Journal Article

Sodium [2′-[(cyclopropanecarbonyl-ethyl-amino)-methyl]-4′-(6-ethoxy-pyridin-3-yl)-6-methoxy-biphenyl-3-yl]-acetate (AM432): A potent, selective prostaglandin D 2 receptor antagonist

Sodium [2′-[(cyclopropanecarbonyl-ethyl-amino)-methyl]-4′-(6-ethoxy-pyridin-3-yl)-6-methoxy-biphenyl-3-yl]-acetate (AM432): A potent, selective prostaglandin D 2 receptor antagonist

by Stock, Nicholas, Volkots, Deborah, Stebbins, Karin, Broadhead, Alex, Stearns, Brian, Roppe, Jeffrey, Parr, Timothy, Baccei, Christopher, Bain, Gretchen, Chapman, Charles, Correa, Lucia, Darlington, Janice, King, Christopher, Lee, Catherine, Lorrain, Daniel S., Prodanovich, Pat, Santini, Angelina, Evans, Jilly F., Hutchinson, John H., Prasit, Peppi
Published in Bioorganic & medicinal chemistry letters (01.02.2011)

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Journal Article

Sodium [2′-[(cyclopropanecarbonyl-ethyl-amino)-methyl]-4′-(6-ethoxy-pyridin-3-yl)-6-methoxy-biphenyl-3-yl]-acetate (AM432): A potent, selective prostaglandin D₂ receptor antagonist

Sodium [2′-[(cyclopropanecarbonyl-ethyl-amino)-methyl]-4′-(6-ethoxy-pyridin-3-yl)-6-methoxy-biphenyl-3-yl]-acetate (AM432): A potent, selective prostaglandin D₂ receptor antagonist

by Stock, Nicholas, Volkots, Deborah, Stebbins, Karin, Broadhead, Alex, Stearns, Brian, Roppe, Jeffrey, Parr, Timothy, Baccei, Christopher, Bain, Gretchen, Chapman, Charles, Correa, Lucia, Darlington, Janice, King, Christopher, Lee, Catherine, Lorrain, Daniel S, Prodanovich, Pat, Santini, Angelina, Evans, Jilly F, Hutchinson, John H, Prasit, Peppi
Published in Bioorganic & medicinal chemistry letters (01.02.2011)

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Journal Article

LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS AND THEIR USE IN THE TREATMENT FIBROSIS

LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS AND THEIR USE IN THE TREATMENT FIBROSIS

by WANG BOWEI, STOCK NICHOLAS SIMON, SEIDERS THOMAS JON, HUTCHINSON JOHN HOWARD, VOLKOTS DEBORAH
Year of Publication 20.11.2013

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Patent

Sodium [2'-[(cyclopropanecarbonyl-ethyl-amino)-methyl]-4'- (6-ethoxy-pyridin-3-yl)-6-methoxy-biphenyl-3-yl]-acetate (AM432): A potent, selective prostaglandin D sub(2) receptor antagonist

Sodium [2'-[(cyclopropanecarbonyl-ethyl-amino)-methyl]-4'- (6-ethoxy-pyridin-3-yl)-6-methoxy-biphenyl-3-yl]-acetate (AM432): A potent, selective prostaglandin D sub(2) receptor antagonist

by Stock, Nicholas, Volkots, Deborah, Stebbins, Karin, Broadhead, Alex, Stearns, Brian, Roppe, Jeffrey, Parr, Timothy, Baccei, Christopher, Bain, Gretchen, Chapman, Charles, Correa, Lucia, Darlington, Janice, King, Christopher, Lee, Catherine, Lorrain, Daniel S, Prodanovich, Pat, Santini, Angelina, Evans, Jilly F, Hutchinson, John H, Prasit, Peppi
Published in Bioorganic & medicinal chemistry letters (01.02.2011)

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Journal Article

POLYCYCLIC COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS

POLYCYCLIC COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS

by CLARK RYAN, ZALATAN DAVID NATHAN, SEIDERS THOMAS JON, STEARNS BRIAN ANDREW, VOLKOTS DEBORAH, ZHAO LUCY, ARRUDA JEANNIE M
Year of Publication 04.09.2012

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Patent

N,N-DISUBSTITUTED AMINOALKYLBIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS

N,N-DISUBSTITUTED AMINOALKYLBIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS

by WANG BOWEI, STOCK NICHOLAS SIMON, TRUONG YEN PHAM, HUTCHINSON JOHN HOWARD, SEIDERS THOMAS JON, SCOTT JILL MELISSA, STEARNS BRIAN ANDREW, VOLKOTS DEBORAH, ROPPE JEFFREY ROGER, ARRUDA JEANNIE M
Year of Publication 30.11.2010

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Patent

Design, synthesis, and structure–Activity relationships of substituted piperazinone-Based transition state factor Xa inhibitors

Design, synthesis, and structure–Activity relationships of substituted piperazinone-Based transition state factor Xa inhibitors

by Su, Ting, Yang, Hua, Volkots, Deborah, Woolfrey, John, Dam, Suiko, Wong, Paul, Sinha, Uma, Scarborough, Robert M, Zhu, Bing-Yan
Published in Bioorganic & medicinal chemistry letters (24.02.2003)

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Journal Article

Polycyclic compounds as lysophosphatidic acid receptor antagonists

Polycyclic compounds as lysophosphatidic acid receptor antagonists

by Zhao, Lucy, Clark, Ryan, Stearns, Brian Andrew, Seiders, Thomas Jon, Volkots, Deborah, Arruda, Jeannie M
Year of Publication 19.06.2018

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Patent

Autotaxin inhibitors and uses thereof

Autotaxin inhibitors and uses thereof

by Hutchinson John Howard, Stock Nicholas Simon, Parr Timothy Andrew, Volkots Deborah, Roppe Jeffrey Roger
Year of Publication 26.12.2017

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Patent

AUTOTAXIN INHIBITORS AND USES THEREOF

AUTOTAXIN INHIBITORS AND USES THEREOF

by VOLKOTS, Deborah, ROPPE, Jeffrey, Roger, HUTCHINSON, John, Howard, PARR, Timothy, Andrew, STOCK, Nicholas, Simon
Year of Publication 27.09.2017

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Patent

antagonistas do receptor do ácido lisofosfatídico e seus usos

antagonistas do receptor do ácido lisofosfatídico e seus usos

by NICHOLAS SIMON STOCK, JOHN HOWARD HUTCHINSON, DEBORAH VOLKOTS, THOMAS JON SEIDERS, BOWEI WANG
Year of Publication 13.09.2016

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Patent

Lysophosphatidic acid receptor antagonists and their use in the treatment fibrosis

Lysophosphatidic acid receptor antagonists and their use in the treatment fibrosis

by WANG BOWEI, STOCK NICHOLAS SIMON, SEIDERS THOMAS JON, HUTCHINSON JOHN HOWARD, VOLKOTS DEBORAH
Year of Publication 01.03.2016

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Patent

LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS AND USES THEREOF

LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS AND USES THEREOF

by HUTCHINSON, JOHN, HOWARD, STOCK, NICHOLAS, SIMON, SEIDERS, THOMAS, JON, VOLKOTS, DEBORAH, WANG, BOWEI
Year of Publication 18.11.2015

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Patent

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