Addressing the Cold Reality of mRNA Vaccine Stability
Crommelin, Daan J.A., Anchordoquy, Thomas J., Volkin, David B., Jiskoot, Wim, Mastrobattista, Enrico
Published in Journal of pharmaceutical sciences (01.03.2021)
Published in Journal of pharmaceutical sciences (01.03.2021)
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Journal Article
Protein–excipient interactions: Mechanisms and biophysical characterization applied to protein formulation development
Kamerzell, Tim J., Esfandiary, Reza, Joshi, Sangeeta B., Middaugh, C. Russell, Volkin, David B.
Published in Advanced drug delivery reviews (01.10.2011)
Published in Advanced drug delivery reviews (01.10.2011)
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Journal Article
Ongoing Challenges to Develop High Concentration Monoclonal Antibody-based Formulations for Subcutaneous Administration: Quo Vadis?
Jiskoot, W, Hawe, Andrea, Menzen, Tim, Volkin, David B., Crommelin, Daan J.A.
Published in Journal of pharmaceutical sciences (01.04.2022)
Published in Journal of pharmaceutical sciences (01.04.2022)
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Journal Article
Evaluating the Role of the Air-Solution Interface on the Mechanism of Subvisible Particle Formation Caused by Mechanical Agitation for an IgG1 mAb
Ghazvini, Saba, Kalonia, Cavan, Volkin, David B., Dhar, Prajnaparamita
Published in Journal of pharmaceutical sciences (01.05.2016)
Published in Journal of pharmaceutical sciences (01.05.2016)
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Journal Article
The Storage and In-Use Stability of mRNA Vaccines and Therapeutics: Not A Cold Case
Oude Blenke, Erik, Örnskov, Eivor, Schöneich, Christian, Nilsson, Gunilla A., Volkin, David B., Mastrobattista, Enrico, Almarsson, Örn, Crommelin, Daan J.A.
Published in Journal of pharmaceutical sciences (01.02.2023)
Published in Journal of pharmaceutical sciences (01.02.2023)
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Journal Article
Vaccine instability in the cold chain: Mechanisms, analysis and formulation strategies
Kumru, Ozan S., Joshi, Sangeeta B., Smith, Dawn E., Middaugh, C. Russell, Prusik, Ted, Volkin, David B.
Published in Biologicals (01.09.2014)
Published in Biologicals (01.09.2014)
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Journal Article
Postproduction Handling and Administration of Protein Pharmaceuticals and Potential Instability Issues
Nejadnik, M. Reza, Randolph, Theodore W., Volkin, David B., Schöneich, Christian, Carpenter, John F., Crommelin, Daan J.A., Jiskoot, Wim
Published in Journal of pharmaceutical sciences (01.08.2018)
Published in Journal of pharmaceutical sciences (01.08.2018)
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Journal Article
A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates
Weidenbacher, Payton A.-B., Sanyal, Mrinmoy, Friedland, Natalia, Tang, Shaogeng, Arunachalam, Prabhu S., Hu, Mengyun, Kumru, Ozan S., Morris, Mary Kate, Fontenot, Jane, Shirreff, Lisa, Do, Jonathan, Cheng, Ya-Chen, Vasudevan, Gayathri, Feinberg, Mark B., Villinger, Francois J., Hanson, Carl, Joshi, Sangeeta B., Volkin, David B., Pulendran, Bali, Kim, Peter S.
Published in Nature communications (17.04.2023)
Published in Nature communications (17.04.2023)
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Journal Article
Effects of Protein Conformation, Apparent Solubility, and Protein–Protein Interactions on the Rates and Mechanisms of Aggregation for an IgG1Monoclonal Antibody
Kalonia, Cavan, Toprani, Vishal, Toth, Ronald, Wahome, Newton, Gabel, Ian, Middaugh, C. Russell, Volkin, David B
Published in The journal of physical chemistry. B (28.07.2016)
Published in The journal of physical chemistry. B (28.07.2016)
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Journal Article
Structural Changes and Aggregation Mechanisms of Two Different Dimers of an IgG2 Monoclonal Antibody
Zhang, Jun, Woods, Christopher, He, Feng, Han, Mei, Treuheit, Michael J, Volkin, David B
Published in Biochemistry (Easton) (18.09.2018)
Published in Biochemistry (Easton) (18.09.2018)
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Journal Article
Structural Characterization of IgG1 mAb Aggregates and Particles Generated Under Various Stress Conditions
Telikepalli, Srivalli N., Kumru, Ozan S., Kalonia, Cavan, Esfandiary, Reza, Joshi, Sangeeta B., Middaugh, C. Russell, Volkin, David B.
Published in Journal of pharmaceutical sciences (01.03.2014)
Published in Journal of pharmaceutical sciences (01.03.2014)
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Journal Article
Evaluating the Combined Impact of Temperature and Application of Interfacial Dilatational Stresses on Surface-mediated Protein Particle Formation in Monoclonal Antibody Formulations
Griffin, Valerie P., Merritt, Kimberly, Vaclaw, Coleman, Whitaker, Neal, Volkin, David B., Ogunyankin, Maria Olu, Pace, Samantha, Dhar, Prajnaparamita
Published in Journal of pharmaceutical sciences (01.03.2022)
Published in Journal of pharmaceutical sciences (01.03.2022)
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Journal Article
A Formulation Development Approach to Identify and Select Stable Ultra–High-Concentration Monoclonal Antibody Formulations With Reduced Viscosities
Whitaker, Neal, Xiong, Jian, Pace, Samantha E., Kumar, Vineet, Middaugh, C. Russell, Joshi, Sangeeta B., Volkin, David B.
Published in Journal of pharmaceutical sciences (01.11.2017)
Published in Journal of pharmaceutical sciences (01.11.2017)
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Journal Article
Effect of solution properties on the counting and sizing of subvisible particle standards as measured by light obscuration and digital imaging methods
Werk, Tobias, Volkin, David B., Mahler, Hanns-Christian
Published in European journal of pharmaceutical sciences (12.03.2014)
Published in European journal of pharmaceutical sciences (12.03.2014)
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Journal Article
Hydrogen-Deuterium Exchange Mass Spectrometry as an Emerging Analytical Tool for Stabilization and Formulation Development of Therapeutic Monoclonal Antibodies
Majumdar, Ranajoy, Middaugh, C.Russell, Weis, David D., Volkin, David B.
Published in Journal of pharmaceutical sciences (01.02.2015)
Published in Journal of pharmaceutical sciences (01.02.2015)
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Journal Article
Impact of Polysorbate 80 Grade on the Interfacial Properties and Interfacial Stress Induced Subvisible Particle Formation in Monoclonal Antibodies
Vaclaw, Coleman, Merritt, Kimberly, Pringle, Valerie, Whitaker, Neal, Gokhale, Madhushree, Carvalho, Thiago, Pan, Duohai, Liu, Zhihua, Bindra, Dilbir, Khossravi, Mehrnaz, Bolgar, Mark, Volkin, David B., Ogunyankin, Maria O., Dhar, Prajnaparamita
Published in Journal of pharmaceutical sciences (01.02.2021)
Published in Journal of pharmaceutical sciences (01.02.2021)
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Journal Article