Discovery and structure activity relationships of 7-benzyl triazolopyridines as stable, selective, and reversible inhibitors of myeloperoxidase
Shaw, Scott A., Vokits, Benjamin P., Dilger, Andrew K., Viet, Andrew, Clark, Charles G., Abell, Lynn M., Locke, Gregory A., Duke, Gerald, Kopcho, Lisa M., Dongre, Ashok, Gao, Ji, Krishnakumar, Arathi, Jusuf, Sutjano, Khan, Javed, Spronk, Steven A., Basso, Michael D., Zhao, Lei, Cantor, Glenn H., Onorato, Joelle M., Wexler, Ruth R., Duclos, Franck, Kick, Ellen K.
Published in Bioorganic & medicinal chemistry (15.11.2020)
Published in Bioorganic & medicinal chemistry (15.11.2020)
Get full text
Journal Article
Synthesis of Biologically Active Piperidine Metabolites of Clopidogrel: Determination of Structure and Analyte Development
Shaw, Scott A, Balasubramanian, Balu, Bonacorsi, Samuel, Cortes, Janet Caceres, Cao, Kevin, Chen, Bang-Chi, Dai, Jun, Decicco, Carl, Goswami, Animesh, Guo, Zhiwei, Hanson, Ronald, Humphreys, W. Griffith, Lam, Patrick Y. S, Li, Wenying, Mathur, Arvind, Maxwell, Brad D, Michaudel, Quentin, Peng, Li, Pudzianowski, Andrew, Qiu, Feng, Su, Shun, Sun, Dawn, Tymiak, Adrienne A, Vokits, Benjamin P, Wang, Bei, Wexler, Ruth, Wu, Dauh-Rurng, Zhang, Yingru, Zhao, Rulin, Baran, Phil S
Published in Journal of organic chemistry (17.07.2015)
Published in Journal of organic chemistry (17.07.2015)
Get full text
Journal Article
Triazolopyrimidines identified as reversible myeloperoxidase inhibitors
Duclos, Franck, Abell, Lynn M., Harden, David G., Pike, Kristen, Nowak, Kimberly, Locke, Gregory A., Duke, Gerald J., Liu, Xiaoqin, Fernando, Gayani, Shaw, Scott A., Vokits, Benjamin P., Wurtz, Nicholas R., Viet, Andrew, Valente, Meriah N., Stachura, Sylwia, Sleph, Paul, Khan, Javed A., Gao, Ji, Dongre, Ashok R., Zhao, Lei, Wexler, Ruth R., Gordon, David A., Kick, Ellen K.
Published in MedChemComm (01.11.2017)
Published in MedChemComm (01.11.2017)
Get full text
Journal Article
Correction to “Synthesis of Biologically Active Piperidine Metabolites of Clopidogrel: Determination of Structure and Analyte Development”
Shaw, Scott A, Balasubramanian, Balu, Bonacorsi, Samuel, Caceres Cortes, Janet, Cao, Kevin, Chen, Bang-Chi, Dai, Jun, Decicco, Carl, Goswami, Animesh, Guo, Zhiwei, Hanson, Ronald, Humphreys, W. Griffith, Lam, Patrick Y. S, Li, Wenying, Mathur, Arvind, Maxwell, Brad D, Michaudel, Quentin, Peng, Li, Pudzianowski, Andrew, Qiu, Feng, Su, Shun, Sun, Dawn, Tymiak, Adrienne A, Vokits, Benjamin P, Wang, Bei, Wexler, Ruth, Wu, Dauh-Rurng, Zhang, Yingru, Zhao, Rulin, Baran, Phil S
Published in Journal of organic chemistry (18.09.2015)
Published in Journal of organic chemistry (18.09.2015)
Get full text
Journal Article
Discovery of (1R,2R)-N-(4-(6-isopropylpyridin-2-yl)-3-(2-methyl-2H-indazol-5-yl)isothiazol-5-yl)-2-methylcyclopropanecarboxamide, a potent and orally efficacious mGlu5 receptor negative allosteric modulator
Hao, Junliang, Dehlinger, Veronique, Fivush, Adam M., Rudyk, Helene C.E., Britton, Thomas C., Hollinshead, Sean P., Vokits, Benjamin P., Clark, Barry P., Henry, Steven S., Massey, Steven M., Peng, Langu, Dressman, Bruce A., Heinz, Beverly A., Roberts, Edda F., Bracey-Walker, Mallorie R., Swanson, Steven, Catlow, John T., Love, Patrick L., Tepool, Anita D., Peters, Steven C., Simmons, Rosa Maria A., Iyengar, Smriti, McKinzie, David L., Monn, James A.
Published in Bioorganic & medicinal chemistry letters (01.03.2013)
Published in Bioorganic & medicinal chemistry letters (01.03.2013)
Get full text
Journal Article
Decarboxylative alkenylation
Edwards, Jacob T., Merchant, Rohan R., McClymont, Kyle S., Knouse, Kyle W., Qin, Tian, Malins, Lara R., Vokits, Benjamin, Shaw, Scott A., Bao, Deng-Hui, Wei, Fu-Liang, Zhou, Ting, Eastgate, Martin D., Baran, Phil S.
Published in Nature (London) (11.05.2017)
Published in Nature (London) (11.05.2017)
Get full text
Journal Article
Nickel-Catalyzed Cross-Coupling of Redox-Active Esters with Boronic Acids
Wang, Jie, Qin, Tian, Chen, Tie-Gen, Wimmer, Laurin, Edwards, Jacob T., Cornella, Josep, Vokits, Benjamin, Shaw, Scott A., Baran, Phil S.
Published in Angewandte Chemie International Edition (08.08.2016)
Published in Angewandte Chemie International Edition (08.08.2016)
Get full text
Journal Article
Overcoming Limitations in Decarboxylative Arylation via Ag–Ni Electrocatalysis
Palkowitz, Maximilian D., Laudadio, Gabriele, Kolb, Simon, Choi, Jin, Oderinde, Martins S., Ewing, Tamara El-Hayek, Bolduc, Philippe N., Chen, TeYu, Zhang, Hao, Cheng, Peter T. W., Zhang, Benxiang, Mandler, Michael D., Blasczak, Vanna D., Richter, Jeremy M., Collins, Michael R., Schioldager, Ryan L., Bravo, Martin, Dhar, T. G. Murali, Vokits, Benjamin, Zhu, Yeheng, Echeverria, Pierre-Georges, Poss, Michael A., Shaw, Scott A., Clementson, Sebastian, Petersen, Nadia Nasser, Mykhailiuk, Pavel K., Baran, Phil S.
Published in Journal of the American Chemical Society (28.09.2022)
Published in Journal of the American Chemical Society (28.09.2022)
Get full text
Journal Article
Ni-catalyzed Cross-coupling of Redox-Active Esters with Boronic Acids
Wang, Jie, Qin, Tian, Chen, Tie-Gen, Wimmer, Laurin, Edwards, Jacob T., Cornella, Josep, Vokits, Benjamin, Shaw, Scott A., Baran, Phil S.
Published in Angewandte Chemie International Edition (06.07.2016)
Published in Angewandte Chemie International Edition (06.07.2016)
Get full text
Journal Article
RXFP1 효능제
MATHUR ARVIND, LI JIANQING, CLARKE ADAM JAMES, PASUNOORI LAXMAN, FRIENDS TODD J, WURTZ NICHOLAS R, MYERS MICHAEL C, PINTO DONALD J.P, PABBISETTY KUMAR BALASHANMUGA, SHAW SCOTT A, TORA GEORGE O, SU SHUN, VOKITS BENJAMIN P
Year of Publication 28.06.2024
Get full text
Year of Publication 28.06.2024
Patent
RXFP1 효능제
MATHUR ARVIND, LI JIANQING, CLARKE ADAM JAMES, FRIENDS TODD J, ORWAT MICHAEL J, BARRE DURGA BUCHI RAJU, MYERS MICHAEL C, PINTO DONALD J.P, KUMAR SREEKANTHA RATNA, PABBISETTY KUMAR BALASHANMUGA, SHAW SCOTT A, SMITH II LEON M, SU SHUN, VOKITS BENJAMIN P, POTTURI HIMA KIRAN
Year of Publication 21.06.2024
Get full text
Year of Publication 21.06.2024
Patent
RXFP1 효능제
MATHUR ARVIND, O'MALLEY DANIEL, LI JIANQING, CLARKE ADAM JAMES, LAWRENCE R. MICHAEL, PASUNOORI LAXMAN, FRIENDS TODD J, ORWAT MICHAEL J, WURTZ NICHOLAS R, BHOGADI VIKRAM, MYERS MICHAEL C, PINTO DONALD J.P, KUMAR SREEKANTHA RATNA, PABBISETTY KUMAR BALASHANMUGA, SHAW SCOTT A, SMITH II LEON M, TORA GEORGE O, SU SHUN, SRINIVAS PITANI VEERA VENKATA, FINLAY HEATHER, HEGDE SUBRAMANYA, BILDER DONNA M, VOKITS BENJAMIN P, POTTURI HIMA KIRAN
Year of Publication 28.06.2024
Get full text
Year of Publication 28.06.2024
Patent
Triazolopyrimidines identified as reversible myeloperoxidase inhibitorsElectronic supplementary information (ESI) available: General synthetic methods, key compound characterization, assay methods, and crystallographic information are available in the ESI. See DOI: 10.1039/c7md00268h
Duclos, Franck, Abell, Lynn M, Harden, David G, Pike, Kristen, Nowak, Kimberly, Locke, Gregory A, Duke, Gerald J, Liu, Xiaoqin, Fernando, Gayani, Shaw, Scott A, Vokits, Benjamin P, Wurtz, Nicholas R, Viet, Andrew, Valente, Meriah N, Stachura, Sylwia, Sleph, Paul, Khan, Javed A, Gao, Ji, Dongre, Ashok R, Zhao, Lei, Wexler, Ruth R, Gordon, David A, Kick, Ellen K
Year of Publication 16.11.2017
Year of Publication 16.11.2017
Get full text
Journal Article
Triazolopyrimidines identified as reversible myeloperoxidase inhibitors† †Electronic supplementary information (ESI) available: General synthetic methods, key compound characterization, assay methods, and crystallographic information are available in the ESI. See DOI: 10.1039/c7md00268h
Duclos, Franck, Abell, Lynn M., Harden, David G., Pike, Kristen, Nowak, Kimberly, Locke, Gregory A., Duke, Gerald J., Liu, Xiaoqin, Fernando, Gayani, Shaw, Scott A., Vokits, Benjamin P., Wurtz, Nicholas R., Viet, Andrew, Valente, Meriah N., Stachura, Sylwia, Sleph, Paul, Khan, Javed A., Gao, Ji, Dongre, Ashok R., Zhao, Lei, Wexler, Ruth R., Gordon, David A., Kick, Ellen K.
Published in MedChemComm (26.10.2017)
Published in MedChemComm (26.10.2017)
Get full text
Journal Article
Nickel-Catalyzed Cross-Coupling of Redox-Active Esters with Boronic Acids
Wang, Jie, Qin, Tian, Chen, Tie-Gen, Wimmer, Laurin, Edwards, Jacob T., Cornella, Josep, Vokits, Benjamin, Shaw, Scott A., Baran, Phil S.
Published in Angewandte Chemie (08.08.2016)
Published in Angewandte Chemie (08.08.2016)
Get full text
Journal Article
3-INDAZOLYL-4-PYRIDYLISOTHIAZOLES
HOLLINSHEAD SEAN PATRICK, BRITTON THOMAS CHARLES, DEHLINGER VERONIQUE, VOKITS BENJAMIN PAUL, FIVUSH ADAM MICHAEL
Year of Publication 08.11.2010
Get full text
Year of Publication 08.11.2010
Patent