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Aging of Preleukemic Thymocytes Drives CpG Island Hypermethylation in T-Cell Acute Lymphoblastic Leukemia
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Tet2 is a tumor suppressor in the pre-leukemic phase of T-cell acute lymphoblastic leukemia
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RPPA-Based Protein Profiling Reveals Enhanced PI3K/AKT/mTOR Signaling in ETV6/RUNX1-Positive Acute Lymphoblastic Leukemia Patients with Low CD200 Expression
Ghazavi, Farzaneh, Serafin, Valentina, Rondou, Pieter, Lammens, Tim, Speleman, Frank, Accordi, Benedetta, De Moerloose, Barbara, Vlierberghe, Pieter Van
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Lens epithelium-derived growth factor/p75 is dispensable for hematopoiesis but essential for MLL-rearranged leukemogenesis
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Published in Experimental hematology (01.09.2017)
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Oncogenic ZEB2 activation drives sensitivity toward KDM1A inhibition in T-cell acute lymphoblastic leukemia
Goossens, Steven, Peirs, Sofie, Van Loocke, Wouter, Wang, Jueqiong, Takawy, Mina, Matthijssens, Filip, Sonderegger, Stefan E., Haigh, Katharina, Nguyen, Thao, Vandamme, Niels, Costa, Magdaline, Carmichael, Catherine, Van Nieuwerburgh, Filip, Deforce, Dieter, Kleifeld, Oded, Curtis, David J., Berx, Geert, Van Vlierberghe, Pieter, Haigh, Jody J.
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A Tumor Suppressor Enhancer of PTEN in T-cell development and leukemia
Tottone, Luca, Lancho, Olga, Loh, Jui-Wan, Singh, Amartya, Kimura, Shunsuke, Roels, Juliette, Kuchmiy, Anna, Strubbe, Steven, Lawlor, Matthew A, da Silva-Diz, Victoria, Luo, Shirley, Gachet, Stéphanie, García-Prieto, Carlos A, Hagelaar, Rico, Esteller, Manel, Meijerink, Jules P P, Soulier, Jean, Taghon, Tom, Van Vlierberghe, Pieter, Mullighan, Charles G, Khiabanian, Hossein, Rocha, Pedro P, Herranz, Daniel
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Deletion 6q Drives T-cell Leukemia Progression by Ribosome Modulation
Gachet, Stéphanie, El-Chaar, Tiama, Avran, David, Genesca, Eulalia, Catez, Frédéric, Quentin, Samuel, Delord, Marc, Thérizols, Gabriel, Briot, Delphine, Meunier, Godelieve, Hernandez, Lucie, Pla, Marika, Smits, Willem K, Buijs-Gladdines, Jessica G, Van Loocke, Wouter, Menschaert, Gerben, André-Schmutz, Isabelle, Taghon, Tom, Van Vlierberghe, Pieter, Meijerink, Jules P, Baruchel, André, Dombret, Hervé, Clappier, Emmanuelle, Diaz, Jean-Jacques, Gazin, Claude, de Thé, Hugues, Sigaux, François, Soulier, Jean
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The TLX1 oncogene drives aneuploidy in T cell transformation
De Keersmaecker, Kim, Real, Pedro J, Gatta, Giusy Della, Palomero, Teresa, Sulis, Maria Luisa, Tosello, Valeria, Van Vlierberghe, Pieter, Barnes, Kelly, Castillo, Mireia, Sole, Xavier, Hadler, Michael, Lenz, Jack, Aplan, Peter D, Kelliher, Michelle, Kee, Barbara L, Pandolfi, Pier Paolo, Kappes, Dietmar, Gounari, Fotini, Petrie, Howard, Van der Meulen, Joni, Speleman, Frank, Paietta, Elisabeth, Racevskis, Janis, Wiernik, Peter H, Rowe, Jacob M, Soulier, Jean, Avran, David, Cavé, Hélène, Dastugue, Nicole, Raimondi, Susana, Meijerink, Jules P P, Cordon-Cardo, Carlos, Califano, Andrea, Ferrando, Adolfo A
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PHF6 mutations in adult acute myeloid leukemia
Van Vlierberghe, P, Patel, J, Abdel-Wahab, O, Lobry, C, Hedvat, C V, Balbin, M, Nicolas, C, Payer, A R, Fernandez, H F, Tallman, M S, Paietta, E, Melnick, A, Vandenberghe, P, Speleman, F, Aifantis, I, Cools, J, Levine, R, Ferrando, A
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Slowicka, Karolina, Petta, Ioanna, Blancke, Gillian, Hoste, Esther, Dumas, Emilie, Sze, Mozes, Vikkula, Hanna, Radaelli, Enrico, Haigh, Jody J, Jonckheere, Sven, Taminau, Joachim, Vandamme, Niels, Wullaert, Andy, Tulchinsky, Eugene, Nittner, David, Van Vlierberghe, Pieter, De Hertogh, Gert, Baldin, Pamela, Etlioglu, Emre, Wirapati, Pratyaksha, Boon, Louis, Lambrecht, Bart N, Callewaert, Chris, Tejpar, Sabine, Goossens, Steven, Berx, Geert, Vereecke, Lars, van Loo, Geert
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Sanghvi, Viraj R, Mavrakis, Konstantinos J, Van der Meulen, Joni, Boice, Michael, Wolfe, Andrew L, Carty, Mark, Mohan, Prathibha, Rondou, Pieter, Socci, Nicholas D, Benoit, Yves, Taghon, Tom, Van Vlierberghe, Pieter, Leslie, Christina S, Speleman, Frank, Wendel, Hans-Guido
Published in Science signaling (18.11.2014)
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Malignant progression of donor-engrafted clonal hematopoiesis in sibling recipients after stem cell transplantation
Nevejan, Louis, Nollet, Friedel, Devos, Helena, Vynck, Matthijs, Van Vlierberghe, Pieter, Tajdar, Mercedeh, Lodewyck, Tom, Selleslag, Dominik
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Pieters, Tim, Almeida, André, T'Sas, Sara, Lemeire, Kelly, Hochepied, Tino, Berx, Geert, Kentsis, Alex, Goossens, Steven, Van Vlierberghe, Pieter
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Genetic Activation and Therapeutic Targeting of PIM1 in T-Cell Acute Lymphoblastic Leukemia/Lymphoma
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PRC2 Inactivation Induces Resistance to Chemotherapy-Induced Apoptosis By Upregulating the TRAP1 Mitochondrial Chaperone in T-ALL
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Therapeutic Targeting of the Histone Ubiquitination-Methylation Axis in T Cell Leukemia
Ntziachristos, Panagiotis, Arcipowski, Kelly, Martinez, Carlos Alberto, Zhu, Yixing, Volk, Andrew G., Kumar, Suresh, Thomas, Paul M, Van Vlierberghe, Pieter, Hijiya, Nobuko, Marshall, Stacy, Wang, Jack, Wu, Jian, Kelleher, Neil L, Crispino, John
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