ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes
Diao, Jiajie, Liu, Rong, Rong, Yueguang, Zhao, Minglei, Zhang, Jing, Lai, Ying, Zhou, Qiangjun, Wilz, Livia M., Li, Jianxu, Vivona, Sandro, Pfuetzner, Richard A., Brunger, Axel T., Zhong, Qing
Published in Nature (London) (23.04.2015)
Published in Nature (London) (23.04.2015)
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Native α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2
Diao, Jiajie, Burré, Jacqueline, Vivona, Sandro, Cipriano, Daniel J, Sharma, Manu, Kyoung, Minjoung, Südhof, Thomas C, Brunger, Axel T
Published in eLife (30.04.2013)
Published in eLife (30.04.2013)
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Complex of human Melanotransferrin and SC57.32 Fab fragment reveals novel interdomain arrangement with ferric N-lobe and open C-lobe
Hayashi, Kristyn, Longenecker, Kenton L., Liu, Yi-Liang, Faust, Bryan, Prashar, Aditi, Hampl, Johannes, Stoll, Vincent, Vivona, Sandro
Published in Scientific reports (12.01.2021)
Published in Scientific reports (12.01.2021)
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228 Engineered human IL-2/IL-2Rß orthogonal pairs selectively enhance anti-GPC3 CAR T cells in vivo to drive complete responses in solid epithelial tumor models
Aspuria, Paul-Joseph, Semana, Marie, Cheng, Ivan, Ratti, Navneet, Ramadass, Mahalaksmi, Rokkam, Deepti, Ali, Mohammed, Bauer, Michele, Burgess, Ryan, Rosas, Henry, Vivona, Sandro, Zheng, George, Lupardus, Patrick, Oft, Martin
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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1053 Preclinical pharmacodynamic characterization of STK-026: a novel IL-12 partial agonist for cancer with maintained CD8 T cell activity, reduced NK-mediated toxicity and an improved therapeutic window
Koliesnik, Zhenya, Totagrande, Michael, Burgess, Ryan, Tran, Kim Q, Bauer, Michele, Jayaraman, Bharghavi, Buffone, Cindy, Balasubrahmanyam, Priyanka, Emmerich, Jan, Chaturvedi, Deepti, Rokkam, Deepti, Malefyt, Rene De Waal, Greb, Heiko, Ratti, Navneet, Vivona, Sandro, Kastelein, Robert, Lupardus, Patrick, Zuniga, Luis, Rosen, David B, Oft, Martin
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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The Longin SNARE VAMP7/TI-VAMP Adopts a Closed Conformation
Vivona, Sandro, Liu, Corey W., Strop, Pavel, Rossi, Valeria, Filippini, Francesco, Brunger, Axel T.
Published in The Journal of biological chemistry (04.06.2010)
Published in The Journal of biological chemistry (04.06.2010)
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Mechanistic insights into the recycling machine of the SNARE complex
Zhao, Minglei, Wu, Shenping, Zhou, Qiangjun, Vivona, Sandro, Cipriano, Daniel J., Cheng, Yifan, Brunger, Axel T.
Published in Nature (London) (05.02.2015)
Published in Nature (London) (05.02.2015)
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Properties of native brain α-synuclein
Burré, Jacqueline, Vivona, Sandro, Diao, Jiajie, Sharma, Manu, Brunger, Axel T., Südhof, Thomas C.
Published in Nature (London) (13.06.2013)
Published in Nature (London) (13.06.2013)
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Reduction Triggered In Situ Polymerization in Living Mice
Cui, Lina, Vivona, Sandro, Smith, Bryan Ronain, Kothapalli, Sri-Rajasekhar, Liu, Jun, Ma, Xiaowei, Chen, Zixin, Taylor, Madelynn, Kierstead, Paul H, Fréchet, Jean M.J, Gambhir, Sanjiv S, Rao, Jianghong
Published in Journal of the American Chemical Society (09.09.2020)
Published in Journal of the American Chemical Society (09.09.2020)
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Structure of human DPEP3 in complex with the SC-003 antibody Fab fragment reveals basis for lack of dipeptidase activity
Hayashi, Kristyn, Longenecker, Kenton L., Koenig, Patrick, Prashar, Aditi, Hampl, Johannes, Stoll, Vincent, Vivona, Sandro
Published in Journal of structural biology (01.07.2020)
Published in Journal of structural biology (01.07.2020)
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Abstract 1512: OrthoCARs: Engineered human IL-2/IL-2Rb orthogonal pairs selectively enhance CAR T cell antitumor efficacy by driving T cell expansion and fitness
Aspuria, Paul-Joseph P., Vivona, Sandro, Bauer, Michele, Semana, Marie, Ratti, Navneet, McCauley, Scott, Riener, Romina, Malefyt, Rene de Waal, Rokkam, Deepti, Emmerich, Jan, Lupardus, Patrick J., Kastelein, Rob A., Oft, Martin
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Abstract 1744: STK-012, an alpha/beta selective IL-2 mutein for the activation of the antigen-activated T cells in solid tumor
Emmerich, Jan, Bauer, Michele, Semana, Marie, Jayaraman, Bhargavi, Vivona, Sandro, McCauley, Scott, Riener, Romina, Malefyt, Rene De Waal, Aspuria, Paul-Joseph, Rokkam, Deepti, Lupardus, Patrick, Kastelein, Rob, Oft, Martin
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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OrthoCARs: Engineered human IL-2/IL-2Rb orthogonal pairs selectively enhance CAR T cell antitumorefficacy
Aspuria, Paul-Joseph, Bauer, Michael A, vivona, Sandro, de Waal Malefyt, Rene, Kastelein, Rob, Oft, Martin, Emmerich, Jan, Rokkam, Deepti, Kauder, Steven E, McCauley, Scott, Riener, Romina, Verma, Rakesh
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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Abstract 3252: Ortho CARs: Engineered human IL-2/IL-2Rb orthogonal pairs selectively enhance CAR T cell anti-tumor efficacy and durability of response
Aspuria, Paul-Joseph, Bauer, Michele, Vivona, Sandro, Kauder, Steven E., McCauley, Scott, Riener, Romina, Malefyte, Rene De Waal, Ratti, Navneet, Rokkam, Deepti, Emmerich, Jan, Lupardus, Patrick J., Kastelein, Rob A., Oft, Martin
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Processive ATP-driven Substrate Disassembly by the N-Ethylmaleimide-sensitive Factor (NSF) Molecular Machine
Cipriano, Daniel J., Jung, Jaemyeong, Vivona, Sandro, Fenn, Timothy D., Brunger, Axel T., Bryant, Zev
Published in The Journal of biological chemistry (09.08.2013)
Published in The Journal of biological chemistry (09.08.2013)
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