Glyburide inhibits the Cryopyrin/Nalp3 inflammasome
Lamkanfi, Mohamed, Mueller, James L, Vitari, Alberto C, Misaghi, Shahram, Fedorova, Anna, Deshayes, Kurt, Lee, Wyne P, Hoffman, Hal M, Dixit, Vishva M
Published in The Journal of cell biology (05.10.2009)
Published in The Journal of cell biology (05.10.2009)
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Inflammasome-dependent release of the alarmin HMGB1 in endotoxemia
Lamkanfi, Mohamed, Sarkar, Anasuya, Vande Walle, Lieselotte, Vitari, Alberto C, Amer, Amal O, Wewers, Mark D, Tracey, Kevin J, Kanneganti, Thirumala-Devi, Dixit, Vishva M
Published in The Journal of immunology (1950) (01.10.2010)
Published in The Journal of immunology (1950) (01.10.2010)
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SPAK/OSR1 regulate NKCC1 and WNK activity: analysis of WNK isoform interactions and activation by T-loop trans-autophosphorylation
Thastrup, Jacob O, Rafiqi, Fatema H, Vitari, Alberto C, Pozo-Guisado, Eulalia, Deak, Maria, Mehellou, Youcef, Alessi, Dario R
Published in Biochemical journal (01.01.2012)
Published in Biochemical journal (01.01.2012)
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Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1
Vitari, Alberto C, Thastrup, Jacob, Rafiqi, Fatema H, Deak, Maria, Morrice, Nick A, Karlsson, Håkan K R, Alessi, Dario R
Published in Biochemical journal (01.07.2006)
Published in Biochemical journal (01.07.2006)
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Regulation of activity and localization of the WNK1 protein kinase by hyperosmotic stress
Zagórska, Anna, Pozo-Guisado, Eulalia, Boudeau, Jérôme, Vitari, Alberto C, Rafiqi, Fatema H, Thastrup, Jacob, Deak, Maria, Campbell, David G, Morrice, Nick A, Prescott, Alan R, Alessi, Dario R
Published in The Journal of cell biology (01.01.2007)
Published in The Journal of cell biology (01.01.2007)
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Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5
Mavrakis, Konstantinos J., McDonald, E. Robert, Schlabach, Michael R., Billy, Eric, Hoffman, Gregory R., deWeck, Antoine, Ruddy, David A., Venkatesan, Kavitha, Yu, Jianjun, McAllister, Gregg, Stump, Mark, deBeaumont, Rosalie, Ho, Samuel, Yue, Yingzi, Liu, Yue, Yan-Neale, Yan, Yang, Guizhi, Lin, Fallon, Yin, Hong, Gao, Hui, Kipp, D. Randal, Zhao, Songping, McNamara, Joshua T., Sprague, Elizabeth R., Zheng, Bing, Lin, Ying, Cho, Young Shin, Gu, Justin, Crawford, Kenneth, Ciccone, David, Vitari, Alberto C., Lai, Albert, Capka, Vladimir, Hurov, Kristen, Porter, Jeffery A., Tallarico, John, Mickanin, Craig, Lees, Emma, Pagliarini, Raymond, Keen, Nicholas, Schmelzle, Tobias, Hofmann, Francesco, Stegmeier, Frank, Sellers, William R.
Published in Science (American Association for the Advancement of Science) (11.03.2016)
Published in Science (American Association for the Advancement of Science) (11.03.2016)
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WNK1, the kinase mutated in an inherited high-blood-pressure syndrome, is a novel PKB (protein kinase B)/Akt substrate
Vitari, Alberto C, Deak, Maria, Collins, Barry J, Morrice, Nick, Prescott, Alan R, Phelan, Anne, Humphreys, Sian, Alessi, Dario R
Published in Biochemical journal (15.02.2004)
Published in Biochemical journal (15.02.2004)
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COP1 is a tumour suppressor that causes degradation of ETS transcription factors
Vitari, Alberto C., Leong, Kevin G., Newton, Kim, Yee, Cindy, O’Rourke, Karen, Liu, Jinfeng, Phu, Lilian, Vij, Rajesh, Ferrando, Ronald, Couto, Suzana S., Mohan, Sankar, Pandita, Ajay, Hongo, Jo-Anne, Arnott, David, Wertz, Ingrid E., Gao, Wei-Qiang, French, Dorothy M., Dixit, Vishva M.
Published in Nature (London) (16.06.2011)
Published in Nature (London) (16.06.2011)
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Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening
McDonald, E. Robert, de Weck, Antoine, Schlabach, Michael R., Billy, Eric, Mavrakis, Konstantinos J., Hoffman, Gregory R., Belur, Dhiren, Castelletti, Deborah, Frias, Elizabeth, Gampa, Kalyani, Golji, Javad, Kao, Iris, Li, Li, Megel, Philippe, Perkins, Thomas A., Ramadan, Nadire, Ruddy, David A., Silver, Serena J., Sovath, Sosathya, Stump, Mark, Weber, Odile, Widmer, Roland, Yu, Jianjun, Yu, Kristine, Yue, Yingzi, Abramowski, Dorothee, Ackley, Elizabeth, Barrett, Rosemary, Berger, Joel, Bernard, Julie L., Billig, Rebecca, Brachmann, Saskia M., Buxton, Frank, Caothien, Roger, Caushi, Justina X., Chung, Franklin S., Cortés-Cros, Marta, deBeaumont, Rosalie S., Delaunay, Clara, Desplat, Aurore, Duong, William, Dwoske, Donald A., Eldridge, Richard S., Farsidjani, Ali, Feng, Fei, Feng, JiaJia, Flemming, Daisy, Forrester, William, Galli, Giorgio G., Gao, Zhenhai, Gauter, François, Gibaja, Veronica, Haas, Kristy, Hattenberger, Marc, Hood, Tami, Hurov, Kristen E., Jagani, Zainab, Jenal, Mathias, Johnson, Jennifer A., Jones, Michael D., Kapoor, Avnish, Korn, Joshua, Liu, Jilin, Liu, Qiumei, Liu, Shumei, Liu, Yue, Loo, Alice T., Macchi, Kaitlin J., Martin, Typhaine, McAllister, Gregory, Meyer, Amandine, Mollé, Sandra, Pagliarini, Raymond A., Phadke, Tanushree, Repko, Brian, Schouwey, Tanja, Shanahan, Frances, Shen, Qiong, Stamm, Christelle, Stephan, Christine, Stucke, Volker M., Tiedt, Ralph, Varadarajan, Malini, Venkatesan, Kavitha, Vitari, Alberto C., Wallroth, Marco, Weiler, Jan, Zhang, Jing, Mickanin, Craig, Myer, Vic E., Porter, Jeffery A., Lai, Albert, Bitter, Hans, Lees, Emma, Keen, Nicholas, Kauffmann, Audrey, Stegmeier, Frank, Hofmann, Francesco, Schmelzle, Tobias, Sellers, William R.
Published in Cell (27.07.2017)
Published in Cell (27.07.2017)
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Glyburide inhibits the Cryopyrin/Nalp3 inflammasome
Lamkanfi, Mohamed, Mueller, James L., Vitari, Alberto C., Misaghi, Shahram, Fedorova, Anna, Deshayes, Kurt, Lee, Wyne P., Hoffman, Hal M., Dixit, Vishva M.
Published in The Journal of experimental medicine (26.10.2009)
Published in The Journal of experimental medicine (26.10.2009)
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