A Scalable Synthesis of a 1,7-Naphthyridine Derivative, a PDE-4 Inhibitor
Jiang, Xinglong, Lee, George T, Villhauer, Edwin B, Prasad, Kapa, Prashad, Mahavir
Published in Organic process research & development (16.07.2010)
Published in Organic process research & development (16.07.2010)
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NVP-DPP728 (1-[[[2-[(5-Cyanopyridin-2-yl)amino]ethyl]amino]acetyl]-2-cyano-(S)-pyrrolidine), a Slow-Binding Inhibitor of Dipeptidyl Peptidase IV
Hughes, Thomas E, Mone, Manisha D, Russell, Mary E, Weldon, Stephen C, Villhauer, Edwin B
Published in Biochemistry (Easton) (07.09.1999)
Published in Biochemistry (Easton) (07.09.1999)
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1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine: A Potent, Selective, and Orally Bioavailable Dipeptidyl Peptidase IV Inhibitor with Antihyperglycemic Properties
Villhauer, Edwin B, Brinkman, John A, Naderi, Goli B, Burkey, Bryan F, Dunning, Beth E, Prasad, Kapa, Mangold, Bonnie L, Russell, Mary E, Hughes, Thomas E
Published in Journal of medicinal chemistry (19.06.2003)
Published in Journal of medicinal chemistry (19.06.2003)
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Conformation of [1-13C,15N]Acetyl-L-carnitine. Rotational-Echo, Double-Resonance Nuclear Magnetic Resonance Spectroscopy
Anderson, Robert C, Gullion, Terry, Joers, Jim M, Shapiro, Michael, Villhauer, Edwin B, Weber, Hans Peter
Published in Journal of the American Chemical Society (01.10.1995)
Published in Journal of the American Chemical Society (01.10.1995)
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Facile and practical synthesis of a cannabinoid-1 antagonist via regio- and stereoselective ring-opening of an aziridinium ion
Villhauer, Edwin B., Shieh, Wen-Chung, Du, Zhengming, Vargas, Kevin, Ciszewski, Lech, Lu, Yansong, Girgis, Michael, Lin, Melissa, Prashad, Mahavir
Published in Tetrahedron (07.11.2009)
Published in Tetrahedron (07.11.2009)
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1-[2-[(5-Cyanopyridin-2-yl)amino]ethylamino]acetyl-2-(S)-pyrrolidinecarbonitrile: A Potent, Selective, and Orally Bioavailable Dipeptidyl Peptidase IV Inhibitor with Antihyperglycemic Properties
Villhauer, Edwin B, Brinkman, John A, Naderi, Goli B, Dunning, Beth E, Mangold, Bonnie L, Mone, Manisha D, Russell, Mary E, Weldon, Stephen C, Hughes, Thomas E
Published in Journal of medicinal chemistry (06.06.2002)
Published in Journal of medicinal chemistry (06.06.2002)
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Antidiabetic agents: a new class of reversible carnitine palmitoyltransferase I inhibitors
Anderson, Robert C, Balestra, Michael, Bell, Philip A, Deems, Rhonda O, Fillers, William S, Foley, James E, Fraser, James D, Mann, William R, Rudin, Markus, Villhauer, Edwin B
Published in Journal of medicinal chemistry (01.09.1995)
Published in Journal of medicinal chemistry (01.09.1995)
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Journal Article
1-[2-[(5-cyanopyridin-2-yl)amino]-ethylamino]acetyl-2-(S)-pyrrolidine-carbonitrile: A potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitor with antihyperglycemic properties
Villhauer, EB, Brinkman, JA, Naderi, GB, Dunning, BE, Mangold, BL, Mone, MD, Russell, ME, Weldon, SC, Hughes, TE
Published in Journal of medicinal chemistry (06.06.2002)
Published in Journal of medicinal chemistry (06.06.2002)
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NVP-DPP728, a Novel, Orally Active Dipeptidyl Peptidase IV Inactivation in Rats
HUGHES, THOMAS E, BALKAN, BORK, VILLHAUER, EDWIN B
Published in Diabetes (New York, N.Y.) (01.05.1999)
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Published in Diabetes (New York, N.Y.) (01.05.1999)
Journal Article
1-[2-[(5-Cyanopyridin-2-yl)amino]-ethylamino]acetyl-2-(S)-pyrrolidine-carbonitri le: A potent, selective, and orally bioavailable Dipeptidyl peptidase IV inhibitor with antihyperglycemic properties
VILLHAUER, Edwin B, BRINKMAN, John A, NADERI, Goli B, DUNNING, Beth E, MANGOLD, Bonnie L, MONE, Manisha D, RUSSELL, Mary E, WELDON, Stephen C, HUGHES, Thomas E
Published in Journal of medicinal chemistry (2002)
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Published in Journal of medicinal chemistry (2002)
Journal Article
Phosphinyloxy propanaminium inner salt derivatives
ANDERSON; ROBERT C, HUGHES; JEFFREY W, FRASER; JAMES D, VILLHAUER; EDWIN B, BEBERNITZ; GREGORY R, SMITH; HOWARD C
Year of Publication 14.05.1996
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Year of Publication 14.05.1996
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