Avidity-based binding to HER2 results in selective killing of HER2-overexpressing cells by anti-HER2/CD3
Slaga, Dionysos, Ellerman, Diego, Lombana, T Noelle, Vij, Rajesh, Li, Ji, Hristopoulos, Maria, Clark, Robyn, Johnston, Jennifer, Shelton, Amy, Mai, Elaine, Gadkar, Kapil, Lo, Amy A, Koerber, James T, Totpal, Klara, Prell, Rodney, Lee, Genee, Spiess, Christoph, Junttila, Teemu T
Published in Science translational medicine (17.10.2018)
Published in Science translational medicine (17.10.2018)
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Bivalent antibody pliers inhibit β-tryptase by an allosteric mechanism dependent on the IgG hinge
Maun, Henry R., Vij, Rajesh, Walters, Benjamin T., Morando, Ashley, Jackman, Janet K., Wu, Ping, Estevez, Alberto, Chen, Xiaocheng, Franke, Yvonne, Lipari, Michael T., Dennis, Mark S., Kirchhofer, Daniel, Ciferri, Claudio, Loyet, Kelly M., Yi, Tangsheng, Eigenbrot, Charles, Lazarus, Robert A., Koerber, James T.
Published in Nature communications (22.12.2020)
Published in Nature communications (22.12.2020)
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An Anti-CLL-1 Antibody-Drug Conjugate for the Treatment of Acute Myeloid Leukemia
Zheng, Bing, Yu, Shang-Fan, Del Rosario, Geoffrey, Leong, Steven R, Lee, Genee Y, Vij, Rajesh, Chiu, Cecilia, Liang, Wei-Ching, Wu, Yan, Chalouni, Cecile, Sadowsky, Jack, Clark, Vanessa, Hendricks, Angela, Poon, Kirsten Achilles, Chu, Wayne, Pillow, Thomas, Schutten, Melissa M, Flygare, John, Polson, Andrew G
Published in Clinical cancer research (15.02.2019)
Published in Clinical cancer research (15.02.2019)
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Massive antibody discovery used to probe structure-function relationships of the essential outer membrane protein LptD
Storek, Kelly M, Chan, Joyce, Vij, Rajesh, Chiang, Nancy, Lin, Zhonghua, Bevers, 3rd, Jack, Koth, Christopher M, Vernes, Jean-Michel, Meng, Y Gloria, Yin, JianPing, Wallweber, Heidi, Dalmas, Olivier, Shriver, Stephanie, Tam, Christine, Schneider, Kellen, Seshasayee, Dhaya, Nakamura, Gerald, Smith, Peter A, Payandeh, Jian, Koerber, James T, Comps-Agrar, Laetitia, Rutherford, Steven T
Published in eLife (25.06.2019)
Published in eLife (25.06.2019)
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A targeted boost-and-sort immunization strategy using Escherichia coli BamA identifies rare growth inhibitory antibodies
Vij, Rajesh, Lin, Zhonghua, Chiang, Nancy, Vernes, Jean-Michel, Storek, Kelly M., Park, Summer, Chan, Joyce, Meng, Y. Gloria, Comps-Agrar, Laetitia, Luan, Peng, Lee, Sophia, Schneider, Kellen, Bevers, Jack, Zilberleyb, Inna, Tam, Christine, Koth, Christopher M., Xu, Min, Gill, Avinash, Auerbach, Marcy R., Smith, Peter A., Rutherford, Steven T., Nakamura, Gerald, Seshasayee, Dhaya, Payandeh, Jian, Koerber, James T.
Published in Scientific reports (08.05.2018)
Published in Scientific reports (08.05.2018)
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Journal Article
A neutralizing anti-gH/gL monoclonal antibody is protective in the guinea pig model of congenital CMV infection
Auerbach, Marcy R, Yan, Donghong, Vij, Rajesh, Hongo, Jo-Anne, Nakamura, Gerald, Vernes, Jean-Michel, Meng, Y Gloria, Lein, Samantha, Chan, Pamela, Ross, Jed, Carano, Richard, Deng, Rong, Lewin-Koh, Nicholas, Xu, Min, Feierbach, Becket
Published in PLoS pathogens (01.04.2014)
Published in PLoS pathogens (01.04.2014)
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Pro-urokinase-type Plasminogen Activator Is a Substrate for Hepsin
Moran, Paul, Li, Wei, Fan, Bin, Vij, Rajesh, Eigenbrot, Charles, Kirchhofer, Daniel
Published in The Journal of biological chemistry (13.10.2006)
Published in The Journal of biological chemistry (13.10.2006)
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Journal Article
Preclinical optimization of Ly6E-targeted ADCs for increased durability and efficacy of anti-tumor response
Dela Cruz Chuh, Josefa, Go, MaryAnn, Chen, Yvonne, Guo, Jun, Rafidi, Hanine, Mandikian, Danielle, Sun, Yonglian, Lin, Zhonghua, Schneider, Kellen, Zhang, Pamela, Vij, Rajesh, Sharpnack, Danielle, Chan, Pamela, de la Cruz, Cecile, Sadowsky, Jack, Seshasayee, Dhaya, Koerber, James T, Pillow, Thomas H, Phillips, Gail D, Rowntree, Rebecca K, Boswell, C Andrew, Kozak, Katherine R, Polson, Andrew G, Polakis, Paul, Yu, Shang-Fan, Dragovich, Peter S, Agard, Nicholas J
Published in mAbs (01.01.2021)
Published in mAbs (01.01.2021)
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An improved and robust DNA immunization method to develop antibodies against extra-cellular loops of multi-transmembrane proteins
Hazen, Meredith, Bhakta, Sunil, Vij, Rajesh, Randle, Steven, Kallop, Dara, Chiang, Vicki, Hötzel, Isidro, Jaiswal, Bijay S, Ervin, Karen E, Li, Bing, Weimer, Robby M, Polakis, Paul, Scheller, Richard H, Junutula, Jagath R, Hongo, Jo-Anne S
Published in mAbs (01.01.2014)
Published in mAbs (01.01.2014)
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Monoclonal antibody targeting the β-barrel assembly machine of Escherichia coli is bactericidal
Storek, Kelly M., Auerbach, Marcy R., Shi, Handuo, Garcia, Natalie K., Sun, Dawei, Nickerson, Nicholas N., Vij, Rajesh, Lin, Zhonghua, Chiang, Nancy, Schneider, Kellen, Wecksler, Aaron T., Skippington, Elizabeth, Nakamura, Gerald, Seshasayee, Dhaya, Koerber, James T., Payandeh, Jian, Smith, Peter A., Rutherford, Steven T.
Published in Proceedings of the National Academy of Sciences - PNAS (03.04.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (03.04.2018)
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Journal Article
Targeting LGR5+ cells with an antibody-drug conjugate for the treatment of colon cancer
Junttila, Melissa R, Mao, Weiguang, Wang, Xi, Wang, Bu-Er, Pham, Thinh, Flygare, John, Yu, Shang-Fan, Yee, Sharon, Goldenberg, David, Fields, Carter, Eastham-Anderson, Jeffrey, Singh, Mallika, Vij, Rajesh, Hongo, Jo-Anne, Firestein, Ron, Schutten, Melissa, Flagella, Kelly, Polakis, Paul, Polson, Andrew G
Published in Science translational medicine (18.11.2015)
Published in Science translational medicine (18.11.2015)
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An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma
Maun, Henry R., Jackman, Janet K., Choy, David F., Loyet, Kelly M., Staton, Tracy L., Jia, Guiquan, Dressen, Amy, Hackney, Jason A., Bremer, Meire, Walters, Benjamin T., Vij, Rajesh, Chen, Xiaocheng, Trivedi, Neil N., Morando, Ashley, Lipari, Michael T., Franke, Yvonne, Wu, Xiumin, Zhang, Juan, Liu, John, Wu, Ping, Chang, Diana, Orozco, Luz D., Christensen, Erin, Wong, Manda, Corpuz, Racquel, Hang, Julie Q., Lutman, Jeff, Sukumaran, Siddharth, Wu, Yan, Ubhayakar, Savita, Liang, Xiaorong, Schwartz, Lawrence B., Babina, Magda, Woodruff, Prescott G., Fahy, John V., Ahuja, Rahul, Caughey, George H., Kusi, Aija, Dennis, Mark S., Eigenbrot, Charles, Kirchhofer, Daniel, Austin, Cary D., Wu, Lawren C., Koerber, James T., Lee, Wyne P., Yaspan, Brian L., Alatsis, Kathila R., Arron, Joseph R., Lazarus, Robert A., Yi, Tangsheng
Published in Cell (03.10.2019)
Published in Cell (03.10.2019)
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COP1 is a tumour suppressor that causes degradation of ETS transcription factors
Vitari, Alberto C., Leong, Kevin G., Newton, Kim, Yee, Cindy, O’Rourke, Karen, Liu, Jinfeng, Phu, Lilian, Vij, Rajesh, Ferrando, Ronald, Couto, Suzana S., Mohan, Sankar, Pandita, Ajay, Hongo, Jo-Anne, Arnott, David, Wertz, Ingrid E., Gao, Wei-Qiang, French, Dorothy M., Dixit, Vishva M.
Published in Nature (London) (16.06.2011)
Published in Nature (London) (16.06.2011)
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Development of a specific immunoassay to selectively measure active tryptase in airway samples
Sperinde, Gizette, Bremer, Meire, Maun, Henry R, Baruch, Amos, Lazarus, Robert A, Koerber, James T, Vij, Rajesh, Yi, Tangsheng, Fischer, Saloumeh K, Staton, Tracy
Published in Bioanalysis (01.10.2020)
Published in Bioanalysis (01.10.2020)
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Journal Article
An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma
Maun, Henry R., Jackman, Janet K., Choy, David F., Loyet, Kelly M., Staton, Tracy L., Jia, Guiquan, Dressen, Amy, Hackney, Jason A., Bremer, Meire, Walters, Benjamin T., Vij, Rajesh, Chen, Xiaocheng, Trivedi, Neil N., Morando, Ashley, Lipari, Michael T., Franke, Yvonne, Wu, Xiumin, Zhang, Juan, Liu, John, Wu, Ping, Chang, Diana, Orozco, Luz D., Christensen, Erin, Wong, Manda, Corpuz, Racquel, Hang, Julie Q., Lutman, Jeff, Sukumaran, Siddharth, Wu, Yan, Ubhayakar, Savita, Liang, Xiaorong, Schwartz, Lawrence B., Babina, Magda, Woodruff, Prescott G., Fahy, John V., Ahuja, Rahul, Caughey, George H., Kusi, Aija, Dennis, Mark S., Eigenbrot, Charles, Kirchhofer, Daniel, Austin, Cary D., Wu, Lawren C., Koerber, James T., Lee, Wyne P., Yaspan, Brian L., Alatsis, Kathila R., Arron, Joseph R., Lazarus, Robert A., Yi, Tangsheng
Published in Cell (23.01.2020)
Published in Cell (23.01.2020)
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An improved and robust DNA immunization method to develop antibodies against extracellular loops of multi-transmembrane proteins
Hazen, Meredith, Bhakta, Sunil, Vij, Rajesh, Randle, Steven, Kallop, Dara, Chiang, Vicki, Hötzel, Isidro, Jaiswal, Bijay S, Ervin, Karen E, Li, Bing, Weimer, Robby M, Polakis, Paul, Scheller, Richard H, Junutula, Jagath R, Hongo, Jo-Anne S
Published in mAbs (01.01.2014)
Published in mAbs (01.01.2014)
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A Neutralizing Anti-gH/gL Monoclonal Antibody Is Protective in the Guinea Pig Model of Congenital CMV Infection: e1004060
Auerbach, Marcy R, Yan, Donghong, Vij, Rajesh, Hongo, Jo-Anne, Nakamura, Gerald, Vernes, Jean-Michel, Meng, Y Gloria, Lein, Samantha, Chan, Pamela, Ross, Jed, Carano, Richard, Deng, Rong, Lewin-Koh, Nicholas, Xu, Min, Feierbach, Becket
Published in PLoS pathogens (01.04.2014)
Published in PLoS pathogens (01.04.2014)
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