Synthesis and in vitro evaluation of novel small molecule inhibitors of bacterial arylamine N-acetyltransferases (NATs)
Brooke, Edward W., Davies, Stephen G., Mulvaney, Andrew W., Okada, Minoru, Pompeo, Frédérique, Sim, Edith, Vickers, Richard J., Westwood, Isaac M.
Published in Bioorganic & medicinal chemistry letters (04.08.2003)
Published in Bioorganic & medicinal chemistry letters (04.08.2003)
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Journal Article
Diastereoselective synthesis of quaternary alpha-amino acids from diketopiperazine templates
Davies, Stephen G., Garner, A. Christopher, Ouzman, Jaqueline V. A., Roberts, Paul M., Smith, Andrew D., Snow, Emma J., Thomson, James E., Tamayo, Juan A., Vickers, Richard J.
Published in Organic & biomolecular chemistry (01.01.2007)
Published in Organic & biomolecular chemistry (01.01.2007)
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Journal Article
On the origins of diastereoselectivity in the alkylation of diketopiperazine enolates
Bull, Steven D., Davies, Stephen G., Garner, A. Christopher, Parkes, Alastair L., Roberts, Paul M., Sellers, Thomas G. R., Smith, Andrew D., Tamayo, Juan A., Thomson, James E., Vickers, Richard J.
Published in New journal of chemistry (01.01.2007)
Published in New journal of chemistry (01.01.2007)
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Journal Article
An oxidatively-activated safety catch linker for solid phase synthesis
Davies, Stephen G., Mortimer, Duncan A. B., Mulvaney, AndrewW, Russell, Angela J., Skarphedinsson, Hjalmar, Smith, Andrew D., Vickers, Richard J.
Published in Organic & biomolecular chemistry (01.01.2008)
Published in Organic & biomolecular chemistry (01.01.2008)
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Journal Article
In vivo assessment of SMT19969 in a hamster model of clostridium difficile infection
Weiss, William, Pulse, Mark, Vickers, Richard
Published in Antimicrobial agents and chemotherapy (01.10.2014)
Published in Antimicrobial agents and chemotherapy (01.10.2014)
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Journal Article
Asymmetric synthesis of substituted 1-aminocyclopropane-1-carboxylic acids via diketopiperazine methodology
Bunuel, E, Bull, SD, Davies, SG, Garner, AC, Savory, ED, Smith, AD, Vickers, RJ, Watkin, DJ
Published in Organic & biomolecular chemistry (21.07.2003)
Published in Organic & biomolecular chemistry (21.07.2003)
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Journal Article
The role of topical antibiotic prophylaxis in patients undergoing contaminated head and neck surgery with flap reconstruction
Simons, J P, Johnson, J T, Yu, V L, Vickers, R M, Gooding, W E, Myers, E N, Pou, A M, Wagner, R L, Grandis, J R
Published in The Laryngoscope (01.02.2001)
Published in The Laryngoscope (01.02.2001)
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Journal Article
668. Quality of Life Changes in Patients with Clostridium difficile Infection (CDI): A Randomized, Double-Blind Trial of Ridinilazole (RDZ) Compared with Vancomycin (VAN)
Paul, Sumita, Vickers, Richard, Garey, Kevin W
Published in Open forum infectious diseases (23.10.2019)
Published in Open forum infectious diseases (23.10.2019)
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Journal Article
A randomised phase 1 study to investigate safety, pharmacokinetics and impact on gut microbiota following single and multiple oral doses in healthy male subjects of SMT19969, a novel agent for Clostridium difficile infections
Vickers, Richard, Robinson, Neil, Best, Emma, Echols, Roger, Tillotson, Glenn, Wilcox, Mark
Published in BMC infectious diseases (25.02.2015)
Published in BMC infectious diseases (25.02.2015)
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Journal Article
1369. Combined Analysis of the In Vitro Activity of Ridinilazole (RDZ) Against More Than 500 Clostridium difficile (CD) Clinical Isolates and Impact of RDZ on Cell Morphology
Duperchy, Esther, Bassères, Eugénie, Garey, Kevin, Vickers, Richard
Published in Open forum infectious diseases (26.11.2018)
Published in Open forum infectious diseases (26.11.2018)
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Journal Article
1361. Pharmacokinetics and Safety of Ridinilazole (RDZ), a Potential New Therapy for Clostridium difficile Infection (CDI): From Animal Models to Patients
Duperchy, Esther, Chowdhury, Sumita, Vickers, Richard, Robinson, Neil
Published in Open forum infectious diseases (26.11.2018)
Published in Open forum infectious diseases (26.11.2018)
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Journal Article
Methicillin-resistant staphylococcal colonization and infection in a long-term care facility
Muder, R R, Brennen, C, Wagener, M M, Vickers, R M, Rihs, J D, Hancock, G A, Yee, Y C, Miller, J M, Yu, V L
Published in Annals of internal medicine (15.01.1991)
Published in Annals of internal medicine (15.01.1991)
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Journal Article
2578. Narrow-Spectrum Antibiotic Treatment of Clostridium difficile Infection Improves Preservation of Intestinal Metabolic Profile
Park, Seoyoung, Yanagi, Karin, Kane, Anne, Snydman, David R, Vickers, Richard, Thorpe, Cheleste M, Lee, Kyongbum
Published in Open forum infectious diseases (23.10.2019)
Published in Open forum infectious diseases (23.10.2019)
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Journal Article
Synthesis and evaluation of the 2,4-diaminoquinazoline series as anti-tubercular agents
Odingo, Joshua, O’Malley, Theresa, Kesicki, Edward A., Alling, Torey, Bailey, Mai Ann, Early, Julie, Ollinger, Juliane, Dalai, Suryakanta, Kumar, Naresh, Singh, Ravindra Vikram, Hipskind, Philip A., Cramer, Jeffrey W., Ioerger, Thomas, Sacchettini, James, Vickers, Richard, Parish, Tanya
Published in Bioorganic & medicinal chemistry (15.12.2014)
Published in Bioorganic & medicinal chemistry (15.12.2014)
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Journal Article
1774. Ridinilazole (RDZ) for Clostridium difficile infection (CDI): Correlation of In Vitro Spectrum of Activity with Human Gut Microbiome Profiles from a Phase 2 Clinical Trial
Vickers, Richard, Goldstein, Ellie J C, Citron, Diane, Snydman, David, Thorpe, Cheleste M, Kane, Anne V
Published in Open forum infectious diseases (26.11.2018)
Published in Open forum infectious diseases (26.11.2018)
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