Enhanced preservation of the human intestinal microbiota by ridinilazole, a novel Clostridium difficile-targeting antibacterial, compared to vancomycin
Thorpe, Cheleste M, Kane, Anne V, Chang, Justin, Tai, Albert, Vickers, Richard J, Snydman, David R
Published in PloS one (02.08.2018)
Published in PloS one (02.08.2018)
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Utilizing graph machine learning within drug discovery and development
Gaudelet, Thomas, Day, Ben, Jamasb, Arian R, Soman, Jyothish, Regep, Cristian, Liu, Gertrude, Hayter, Jeremy B R, Vickers, Richard, Roberts, Charles, Tang, Jian, Roblin, David, Blundell, Tom L, Bronstein, Michael M, Taylor-King, Jake P
Published in Briefings in bioinformatics (05.11.2021)
Published in Briefings in bioinformatics (05.11.2021)
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Efficacy and safety of ridinilazole compared with vancomycin for the treatment of Clostridium difficile infection: a phase 2, randomised, double-blind, active-controlled, non-inferiority study
Vickers, Richard J, Dr, Tillotson, Glenn S, PhD, Nathan, Richard, MD, Hazan, Sabine, MD, Pullman, John, MD, Lucasti, Christopher, DO, Deck, Kenneth, MD, Yacyshyn, Bruce, Prof, Maliakkal, Benedict, MD, Pesant, Yves, MD, Tejura, Bina, MD, Roblin, David, Prof, Gerding, Dale N, Prof, Wilcox, Mark H, Prof
Published in The Lancet infectious diseases (01.07.2017)
Published in The Lancet infectious diseases (01.07.2017)
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Ridinilazole, a narrow spectrum antibiotic for treatment of Clostridioides difficile infection, enhances preservation of microbiota-dependent bile acids
Qian, Xi, Yanagi, Karin, Kane, Anne V, Alden, Nicholas, Lei, Ming, Snydman, David R, Vickers, Richard J, Lee, Kyongbum, Thorpe, Cheleste M
Published in American journal of physiology: Gastrointestinal and liver physiology (01.08.2020)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.08.2020)
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SMT19969 for Clostridium difficile infection (CDI): in vivo efficacy compared with fidaxomicin and vancomycin in the hamster model of CDI
Sattar, Abdul, Thommes, Pia, Payne, Lloyd, Warn, Peter, Vickers, Richard J
Published in Journal of antimicrobial chemotherapy (01.06.2015)
Published in Journal of antimicrobial chemotherapy (01.06.2015)
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Impact on toxin production and cell morphology in Clostridium difficile by ridinilazole (SMT19969), a novel treatment for C. difficile infection
Bassères, Eugénie, Endres, Bradley T, Khaleduzzaman, Mohammed, Miraftabi, Faranak, Alam, M Jahangir, Vickers, Richard J, Garey, Kevin W
Published in Journal of antimicrobial chemotherapy (01.05.2016)
Published in Journal of antimicrobial chemotherapy (01.05.2016)
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Evaluation of the antimicrobial activity of ridinilazole and six comparators against Chinese, Japanese and South Korean strains of Clostridioides difficile
Collins, Deirdre A, Wu, Yuan, Tateda, Kazuhiro, Kim, Hee-Jung, Vickers, Richard J, Riley, Thomas V
Published in Journal of antimicrobial chemotherapy (12.03.2021)
Published in Journal of antimicrobial chemotherapy (12.03.2021)
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Antimicrobial susceptibility and ribotypes of Clostridium difficile isolates from a Phase 2 clinical trial of ridinilazole (SMT19969) and vancomycin
Snydman, David R, McDermott, Laura A, Thorpe, Cheleste M, Chang, Justin, Wick, Jenna, Walk, Seth T, Vickers, Richard J
Published in Journal of antimicrobial chemotherapy (01.08.2018)
Published in Journal of antimicrobial chemotherapy (01.08.2018)
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Combating resistance while maintaining innovation: the future of antimicrobial stewardship
Vickers, Richard J, Bassetti, Matteo, Clancy, Cornelius J, Garey, Kevin W, Greenberg, David E, Nguyen, Minh-Hong, Roblin, David, Tillotson, Glenn S, Wilcox, Mark H
Published in Future microbiology (01.10.2019)
Published in Future microbiology (01.10.2019)
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Discovery of 2-Arylbenzoxazoles as Upregulators of Utrophin Production for the Treatment of Duchenne Muscular Dystrophy
Chancellor, Daniel R, Davies, Kay E, De Moor, Olivier, Dorgan, Colin R, Johnson, Peter D, Lambert, Adam G, Lawrence, Daniel, Lecci, Cristina, Maillol, Carole, Middleton, Penny J, Nugent, Gary, Poignant, Séverine D, Potter, Allyson C, Price, Paul D, Pye, Richard J, Storer, Richard, Tinsley, Jonathon M, van Well, Renate, Vickers, Richard, Vile, Julia, Wilkes, Fraser J, Wilson, Francis X, Wren, Stephen P, Wynne, Graham M
Published in Journal of medicinal chemistry (12.05.2011)
Published in Journal of medicinal chemistry (12.05.2011)
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A novel method for imaging the pharmacological effects of antibiotic treatment on Clostridium difficile
Endres, Bradley T., Bassères, Eugénie, Memariani, Ali, Chang, Long, Alam, M. Jahangir, Vickers, Richard J., Kakadiaris, Ioannis A., Garey, Kevin W.
Published in Anaerobe (01.08.2016)
Published in Anaerobe (01.08.2016)
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Automated large-scale culture and medium-throughput chemical screen for modulators of proliferation and viability of human induced pluripotent stem cell-derived neuroepithelial-like stem cells
McLaren, Donna, Gorba, Thorsten, Marguerie de Rotrou, Anita, Pillai, Gopalan, Chappell, Clare, Stacey, Alison, Lingard, Sarah, Falk, Anna, Smith, Austin, Koch, Philipp, Brüstle, Oliver, Vickers, Richard, Tinsley, Jon, Flanders, David, Bello, Paul, Craig, Stewart
Published in Journal of biomolecular screening (01.03.2013)
Published in Journal of biomolecular screening (01.03.2013)
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Identification of arylamine N-acetyltransferase inhibitors as an approach towards novel anti-tuberculars
Westwood, Isaac M., Bhakta, Sanjib, Russell, Angela J., Fullam, Elizabeth, Anderton, Matthew C., Kawamura, Akane, Mulvaney, Andrew W., Vickers, Richard J., Bhowruth, Veemal, Besra, Gurdyal S., Lalvani, Ajit, Davies, Stephen G., Sim, Edith
Published in Protein & cell (2010)
Published in Protein & cell (2010)
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