v-Jun downregulates the SPARC target gene by binding to the proximal promoter indirectly through Sp1 3
CHAMBOREDON, Sandrine, BRIGGS, Joseph, VIAL, Emmanuel, HURAULT, Julien, GALVAGNI, Federico, OLIVIERO, Salvatore, BOS, Timothy, CASTELLAZZI, Marc
Published in Oncogene (26.06.2003)
Published in Oncogene (26.06.2003)
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A Subset of Type I Conventional Dendritic Cells Controls Cutaneous Bacterial Infections through VEGFα-Mediated Recruitment of Neutrophils
Janela, Baptiste, Patel, Amit A., Lau, Mai Chan, Goh, Chi Ching, Msallam, Rasha, Kong, Wan Ting, Fehlings, Michael, Hubert, Sandra, Lum, Josephine, Simoni, Yannick, Malleret, Benoit, Zolezzi, Francesca, Chen, Jinmiao, Poidinger, Michael, Satpathy, Ansuman T., Briseno, Carlos, Wohn, Christian, Malissen, Bernard, Murphy, Kenneth M., Maini, Alexander A., Vanhoutte, Leen, Guilliams, Martin, Vial, Emmanuel, Hennequin, Laurent, Newell, Evan, Ng, Lai Guan, Musette, Philippe, Yona, Simon, Hacini-Rachinel, Feriel, Ginhoux, Florent
Published in Immunity (Cambridge, Mass.) (16.04.2019)
Published in Immunity (Cambridge, Mass.) (16.04.2019)
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Journal Article
Polytherapy with a combination of three repurposed drugs (PXT3003) down-regulates Pmp22 over-expression and improves myelination, axonal and functional parameters in models of CMT1A neuropathy
Chumakov, Ilya, Milet, Aude, Cholet, Nathalie, Primas, Gwenaël, Boucard, Aurélie, Pereira, Yannick, Graudens, Esther, Mandel, Jonas, Laffaire, Julien, Foucquier, Julie, Glibert, Fabrice, Bertrand, Viviane, Nave, Klaus-Armin, Sereda, Michael W, Vial, Emmanuel, Guedj, Mickaël, Hajj, Rodolphe, Nabirotchkin, Serguei, Cohen, Daniel
Published in Orphanet journal of rare diseases (10.12.2014)
Published in Orphanet journal of rare diseases (10.12.2014)
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Journal Article
Combining two repurposed drugs as a promising approach for Alzheimer's disease therapy
Chumakov, Ilya, Nabirotchkin, Serguei, Cholet, Nathalie, Milet, Aude, Boucard, Aurélie, Toulorge, Damien, Pereira, Yannick, Graudens, Esther, Traoré, Sory, Foucquier, Julie, Guedj, Mickael, Vial, Emmanuel, Callizot, Noëlle, Steinschneider, Rémy, Maurice, Tangui, Bertrand, Viviane, Scart-Grès, Catherine, Hajj, Rodolphe, Cohen, Daniel
Published in Scientific reports (08.01.2015)
Published in Scientific reports (08.01.2015)
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Journal Article
Sulfoximines as potent RORc inverse agonists
Ouvry, Gilles, Bihl, Franck, Bouix-Peter, Claire, Christin, Olivier, Defoin-Platel, Claire, Deret, Sophie, Feret, Christophe, Froude, David, Hacini-Rachinel, Feriel, Harris, Craig S., Hervouet, Catherine, Lafitte, Guillaume, Luzy, Anne-Pascale, Musicki, Branislav, Orfila, Danielle, Parnet, Veronique, Pascau, Coralie, Pascau, Jonathan, Pierre, Romain, Raffin, Catherine, Rossio, Patricia, Spiesse, Delphine, Taquet, Nathalie, Thoreau, Etienne, Vatinel, Rodolphe, Vial, Emmanuel, Hennequin, Laurent F.
Published in Bioorganic & medicinal chemistry letters (01.05.2018)
Published in Bioorganic & medicinal chemistry letters (01.05.2018)
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Journal Article
Brimonidine displays anti‐inflammatory properties in the skin through the modulation of the vascular barrier function
Bertino, Béatrice, Blanchet‐Réthoré, Sandrine, Thibaut de Ménonville, Séverine, Reynier, Philippe, Méhul, Bruno, Bogouch, Audrey, Gamboa, Bastien, Dugaret, Anne Sophie, Zugaj, Didier, Petit, Laurent, Roquet, Manon, Piwnica, David, Vial, Emmanuel, Bourdès, Valerie, Voegel, Johannes J., Nonne, Christelle
Published in Experimental dermatology (01.12.2018)
Published in Experimental dermatology (01.12.2018)
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Journal Article
Discovery and process development of a novel TACE inhibitor for the topical treatment of psoriasis
Boiteau, Jean-Guy, Ouvry, Gilles, Arlabosse, Jean-Marie, Astri, Stéphanie, Beillard, Audrey, Bhurruth-Alcor, Yushma, Bonnary, Laetitia, Bouix-Peter, Claire, Bouquet, Karine, Bourotte, Marilyne, Cardinaud, Isabelle, Comino, Catherine, Deprez, Benoît, Duvert, Denis, Féret, Angélique, Hacini-Rachinel, Feriel, Harris, Craig S., Luzy, Anne-Pascale, Mathieu, Arnaud, Millois, Corinne, Orsini, Nicolas, Pascau, Jonathan, Pinto, Artur, Piwnica, David, Polge, Gaëlle, Reitz, Arnaud, Reversé, Kevin, Rodeville, Nicolas, Rossio, Patricia, Spiesse, Delphine, Tabet, Samuel, Taquet, Nathalie, Tomas, Loïc, Vial, Emmanuel, Hennequin, Laurent F.
Published in Bioorganic & medicinal chemistry (15.02.2018)
Published in Bioorganic & medicinal chemistry (15.02.2018)
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Journal Article
Sulfoximines as potent RORγ inverse agonists
Ouvry, Gilles, Bihl, Franck, Bouix-Peter, Claire, Christin, Olivier, Defoin-Platel, Claire, Deret, Sophie, Feret, Christophe, Froude, David, Hacini-Rachinel, Feriel, Harris, Craig S., Hervouet, Catherine, Lafitte, Guillaume, Luzy, Anne-Pascale, Musicki, Branislav, Orfila, Danielle, Parnet, Veronique, Pascau, Coralie, Pascau, Jonathan, Pierre, Romain, Raffin, Catherine, Rossio, Patricia, Spiesse, Delphine, Taquet, Nathalie, Thoreau, Etienne, Vatinel, Rodolphe, Vial, Emmanuel, Hennequin, Laurent F.
Published in Bioorganic & medicinal chemistry letters (01.05.2018)
Published in Bioorganic & medicinal chemistry letters (01.05.2018)
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Journal Article
Protective Effect of Dermal Brimonidine Applications Against UV Radiation-induced Skin Tumors, Epidermal Hyperplasia and Cell Proliferation in the Skin of Hairless Mice
Bouvier, Guy, Learn, Douglas B., Nonne, Christelle, Feraille, Gérard, Vial, Emmanuel, Ruty, Bernard
Published in Photochemistry and photobiology (01.11.2015)
Published in Photochemistry and photobiology (01.11.2015)
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Journal Article
Regulation of Tumor Cell Motility by ERK Mitogen-Activated Protein Kinases
VIAL, EMMANUEL, POUYSSÉGUR, JACQUES
Published in Annals of the New York Academy of Sciences (01.12.2004)
Published in Annals of the New York Academy of Sciences (01.12.2004)
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Journal Article
COMPOSITION COMPRISING TORASEMIDE AND BACLOFEN FOR TREATING NEUROLOGICAL DISORDERS
COHEN, DANIEL, GUEDJ, MICKAEL, CHUMAKOV, ILYA, GUEDJ, MICKAËL, VIAL, EMMANUEL, NABIROCHKIN, SERGUEI, DANIEL COHEN, EMMANUEL VIAL
Year of Publication 30.03.2016
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Year of Publication 30.03.2016
Patent
Discovery and Characterization of CD12681, a Potent ROR Inverse Agonist, Preclinical Candidate for the Topical Treatment of Psoriasis
Ouvry, Gilles, Atrux-Tallau, Nicolas, Bihl, Franck, Bondu, Aline, Bouix-Peter, Claire, Carlavan, Isabelle, Christin, Olivier, Cuadrado, Marie-Josee, Defoin-Platel, Claire, Deret, Sophie, Duvert, Denis, Feret, Christophe, Forissier, Mathieu, Fournier, Jean-Francois, Froude, David, Hacini-Rachinel, Feriel, Harris, Craig Steven, Hervouet, Catherine, Huguet, Helene, Lafitte, Guillaume, Luzy, Anne-Pascale, Musicki, Branislav, Orfila, Danielle, Ozello, Benjamin, Pascau, Coralie, Pascau, Jonathan, Parnet, Veronique, Peluchon, Guillaume, Pierre, Romain, Piwnica, David, Raffin, Catherine, Rossio, Patricia, Spiesse, Delphine, Taquet, Nathalie, Thoreau, Etienne, Vatinel, Rodolphe, Vial, Emmanuel, Hennequin, Laurent Francois
Published in ChemMedChem (20.02.2018)
Published in ChemMedChem (20.02.2018)
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Journal Article
Impact of Minor Structural Modifications on Properties of a Series of mTOR Inhibitors
Ouvry, Gilles, Clary, Laurence, Tomas, Loïc, Aurelly, Michèle, Bonnary, Laetitia, Borde, Emilie, Bouix-Peter, Claire, Chantalat, Laurent, Defoin-Platel, Claire, Deret, Sophie, Forissier, Mathieu, Harris, Craig S, Isabet, Tatiana, Lamy, Laurent, Luzy, Anne-Pascale, Pascau, Jonathan, Soulet, Catherine, Taddei, Alessandro, Taquet, Nathalie, Thoreau, Etienne, Varvier, Emeric, Vial, Emmanuel, Hennequin, Laurent F
Published in ACS medicinal chemistry letters (14.11.2019)
Published in ACS medicinal chemistry letters (14.11.2019)
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Journal Article
BACLOFEN AND ACAMPROSATE BASED THERAPY OF NEUROGICAL DISORDERS
GUEDJ MICKAEL, COHEN DANIEL, VIAL EMMANUEL, CHUMAKOV ILYA, NABIROCHKIN SERGUEI
Year of Publication 30.04.2018
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Year of Publication 30.04.2018
Patent
Discovery and Characterization of CD12681, a Potent RORγ Inverse Agonist, Preclinical Candidate for the Topical Treatment of Psoriasis
Ouvry, Gilles, Atrux‐Tallau, Nicolas, Bihl, Franck, Bondu, Aline, Bouix‐Peter, Claire, Carlavan, Isabelle, Christin, Olivier, Cuadrado, Marie‐Josée, Defoin‐Platel, Claire, Deret, Sophie, Duvert, Denis, Feret, Christophe, Forissier, Mathieu, Fournier, Jean‐François, Froude, David, Hacini‐Rachinel, Fériel, Harris, Craig Steven, Hervouet, Catherine, Huguet, Hélène, Lafitte, Guillaume, Luzy, Anne‐Pascale, Musicki, Branislav, Orfila, Danielle, Ozello, Benjamin, Pascau, Coralie, Pascau, Jonathan, Parnet, Véronique, Peluchon, Guillaume, Pierre, Romain, Piwnica, David, Raffin, Catherine, Rossio, Patricia, Spiesse, Delphine, Taquet, Nathalie, Thoreau, Etienne, Vatinel, Rodolphe, Vial, Emmanuel, Hennequin, Laurent François
Published in ChemMedChem (20.02.2018)
Published in ChemMedChem (20.02.2018)
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Journal Article