Contribution of the precursors and interplay of the pathways in the phospholipid metabolism of the malaria parasite
Wein, Sharon, Ghezal, Salma, Buré, Corinne, Maynadier, Marjorie, Périgaud, Christian, Vial, Henri J., Lefebvre-Tournier, Isabelle, Wengelnik, Kai, Cerdan, Rachel
Published in Journal of lipid research (01.08.2018)
Published in Journal of lipid research (01.08.2018)
Get full text
Journal Article
A chemical proteomics approach for the search of pharmacological targets of the antimalarial clinical candidate albitiazolium in Plasmodium falciparum using photocrosslinking and click chemistry
Penarete-Vargas, Diana Marcela, Boisson, Anaïs, Urbach, Serge, Chantelauze, Hervé, Peyrottes, Suzanne, Fraisse, Laurent, Vial, Henri J
Published in PloS one (03.12.2014)
Published in PloS one (03.12.2014)
Get full text
Journal Article
Phosphatidylinositol 3-monophosphate is involved in toxoplasma apicoplast biogenesis
Tawk, Lina, Dubremetz, Jean-François, Montcourrier, Philippe, Chicanne, Gaëtan, Merezegue, Fabrice, Richard, Véronique, Payrastre, Bernard, Meissner, Markus, Vial, Henri J, Roy, Christian, Wengelnik, Kai, Lebrun, Maryse
Published in PLoS pathogens (01.02.2011)
Published in PLoS pathogens (01.02.2011)
Get full text
Journal Article
Phosphatidylinositol 3-Phosphate, an Essential Lipid in Plasmodium, Localizes to the Food Vacuole Membrane and the Apicoplast
Tawk, Lina, Chicanne, Gaëtan, Dubremetz, Jean-François, Richard, Véronique, Payrastre, Bernard, Vial, Henri J, Roy, Christian, Wengelnik, Kai
Published in Eukaryotic Cell (01.10.2010)
Published in Eukaryotic Cell (01.10.2010)
Get full text
Journal Article
SC83288 is a clinical development candidate for the treatment of severe malaria
Pegoraro, Stefano, Duffey, Maëlle, Otto, Thomas D, Wang, Yulin, Rösemann, Roman, Baumgartner, Roland, Fehler, Stefanie K, Lucantoni, Leonardo, Avery, Vicky M, Moreno-Sabater, Alicia, Mazier, Dominique, Vial, Henri J, Strobl, Stefan, Sanchez, Cecilia P, Lanzer, Michael
Published in Nature communications (31.01.2017)
Published in Nature communications (31.01.2017)
Get full text
Journal Article
Erratum: SC83288 is a clinical development candidate for the treatment of severe malaria
Pegoraro, Stefano, Duffey, Maëlle, Otto, Thomas D., Wang, Yulin, Rösemann, Roman, Baumgartner, Roland, Fehler, Stefanie K., Lucantoni, Leonardo, Avery, Vicky M., Moreno-Sabater, Alicia, Mazier, Dominique, Vial, Henri J., Strobl, Stefan, Sanchez, Cecilia P., Lanzer, Michael
Published in Nature communications (06.04.2017)
Published in Nature communications (06.04.2017)
Get full text
Journal Article
A novel live-dead staining methodology to study malaria parasite viability
Pasini, Erica M, van den Ierssel, Denise, Vial, Henri J, Kocken, Clemens H M
Published in Malaria journal (07.06.2013)
Published in Malaria journal (07.06.2013)
Get full text
Journal Article
Prodrugs of Bisthiazolium Salts Are Orally Potent Antimalarials
Vial, Henri J., Wein, Sharon, Farenc, Christine, Kocken, Clemens, Nicolas, Olivier, Ancelin, Marie Laure, Bressolle, Francoise, Thomas, Alan, Calas, Michèle, Cerami, Anthony C.
Published in Proceedings of the National Academy of Sciences - PNAS (26.10.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (26.10.2004)
Get full text
Journal Article
Symmetrical choline-derived dications display strong anti-kinetoplastid activity
IBRAHIM, Hasan M. S, AL-SALABI, Mohammed I, EL SABBAGH, Nasser, QUASHIE, Neils B, ALKHALDI, Abdulsalam A. M, ESCALE, Roger, SMITH, Terry K, VIAL, Henri J, DE KONING, Harry P
Published in Journal of antimicrobial chemotherapy (01.01.2011)
Published in Journal of antimicrobial chemotherapy (01.01.2011)
Get full text
Journal Article
Potent Inhibitors of Plasmodium Phospholipid Metabolism with a Broad Spectrum of In Vitro Antimalarial Activities
Ancelin, Marie L, Calas, Michèle, Vidal-Sailhan, Valérie, Herbuté, Serge, Ringwald, Pascal, Vial, Henri J
Published in Antimicrobial Agents and Chemotherapy (01.08.2003)
Published in Antimicrobial Agents and Chemotherapy (01.08.2003)
Get full text
Journal Article
In Vivo Antimalarial Activities of Mono- and Bis Quaternary Ammonium Salts Interfering with Plasmodium Phospholipid Metabolism
Ancelin, Marie L, Calas, Michèle, Bonhoure, Anne, Herbute, Serge, Vial, Henri J
Published in Antimicrobial Agents and Chemotherapy (01.08.2003)
Published in Antimicrobial Agents and Chemotherapy (01.08.2003)
Get full text
Journal Article
Potent Antihematozoan Activity of Novel Bisthiazolium Drug T16: Evidence for Inhibition of Phosphatidylcholine Metabolism in Erythrocytes Infected with Babesia and Plasmodium spp
RICHIER, Eric, BIAGINI, Giancarlo A, WEIN, Sharon, BOUDOU, Frederic, BRAY, Patrick G, WARD, Steve A, PRECIGOUT, Eric, CALAS, Michèle, DUBREMETZ, Jean-Francois, VIAL, Henri J
Published in Antimicrobial Agents and Chemotherapy (01.10.2006)
Published in Antimicrobial Agents and Chemotherapy (01.10.2006)
Get full text
Journal Article
Evaluation of amidoxime derivatives as prodrug candidates of potent bis-cationic antimalarials
Berger, Olivier, Ortial, Stéphanie, Wein, Sharon, Denoyelle, Séverine, Bressolle, Françoise, Durand, Thierry, Escale, Roger, Vial, Henri J., Vo-Hoang, Yen
Published in Bioorganic & medicinal chemistry letters (15.08.2019)
Published in Bioorganic & medicinal chemistry letters (15.08.2019)
Get full text
Journal Article
Statistical Model To Evaluate In Vivo Activities of Antimalarial Drugs in a Plasmodium cynomolgi-Macaque Model for Plasmodium vivax Malaria
Kocken, Clemens H M, Remarque, Edmond J, Dubbeld, Martin A, Wein, Sharon, van der Wel, Annemarie, Verburgh, R Joyce, Vial, Henri J, Thomas, Alan W
Published in Antimicrobial Agents and Chemotherapy (01.02.2009)
Published in Antimicrobial Agents and Chemotherapy (01.02.2009)
Get full text
Journal Article
Pharmacological Properties of a New Antimalarial Bisthiazolium Salt, T3, and a Corresponding Prodrug, TE3
NICOLAS, Olivier, MARGOUT, Delphine, TAUDON, Nicolas, WEIN, Sharon, CALAS, Michèle, VIAL, Henri J, BRESSOLLE, Francoise M. M
Published in Antimicrobial Agents and Chemotherapy (01.09.2005)
Published in Antimicrobial Agents and Chemotherapy (01.09.2005)
Get full text
Journal Article