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Synthesis of [1,2,4]triazolo[1,5-a]pyrazines as adenosine A2A receptor antagonists

Synthesis of [1,2,4]triazolo[1,5-a]pyrazines as adenosine A2A receptor antagonists

by DOWLING, James E, VESSELS, Jeffrey T, AYYUB, Eman, PETTER, Russell C, HAQUE, Serajul, HE XI CHANG, VAN VLOTEN, Kurt, KUMARAVEL, Gnanasambandam, ENGBER, Thomas, XIAOWEI JIN, PHADKE, Deepali, WANG, Joy
Published in Bioorganic & medicinal chemistry letters (01.11.2005)

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Journal Article

Sequential Diels−Alder Reaction of in Situ Generated 2,3-Dimethylenepyrrole and Carbodienophiles: Rapid Synthesis of 2,3,6,7-Tetrasubstituted Carbazoles

Sequential Diels−Alder Reaction of in Situ Generated 2,3-Dimethylenepyrrole and Carbodienophiles: Rapid Synthesis of 2,3,6,7-Tetrasubstituted Carbazoles

by Vessels, Jeffrey T, Janicki, Slawomir Z, Petillo, Peter A
Published in Organic letters (01.01.2000)

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Journal Article

O-당단백질-2-아세트아미도-2-데옥시-3-D-글루코피라노시다제 억제제

O-당단백질-2-아세트아미도-2-데옥시-3-D-글루코피라노시다제 억제제

by GIANATASSIO RYAN, ZHANG LEI, GUCKIAN KEVIN M, XIN ZHILI, VESSELS JEFFREY, GENUNG NATHAN, LIN EDWARD YIN SHIANG
Year of Publication 26.05.2021

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Patent

PYRIMIDINE DERIVATIVES USEFUL AS RAF KINASE INHIBITORS

PYRIMIDINE DERIVATIVES USEFUL AS RAF KINASE INHIBITORS

by JONES JOHN HOWARD, TANAKA HIROKO, POWELL NOEL, RAIMUNDO BRIAN, WYNN THOMAS, GUAN BING, XIN ZHILI, COSSROW JENNIFER, FRANKLIN LIOYD, LUGOVSKOY ALEXEY, KUMARAVEL GNANASAMBANDAM, LANE BENJAMIN, CHEN WEIRONG, PENG HAIRUO, VESSELS JEFFREY, LITTKE ADAM
Year of Publication 10.03.2016

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Patent

COMPOUND USEFUL AS RAF KINASE INHIBITOR

COMPOUND USEFUL AS RAF KINASE INHIBITOR

by JONES JOHN HOWARD, TANAKA HIROKO, POWELL NOEL, RAIMUNDO BRIAN, WYNN THOMAS, GUAN BING, XIN ZHILI, COSSROW JENNIFER, FRANKLIN LIOYD, LUGOVSKOY ALEXEY, KUMARAVEL GNANASAMBANDAM, LANE BENJAMIN, CHEN WEIRONG, PENG HAIRUO, VESSELS JEFFREY, LITTKE ADAM
Year of Publication 25.06.2015

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Patent

O-glycoprotein-2-acetamido-2-deoxy-3-D-glycopyranosidase inhibitors

O-glycoprotein-2-acetamido-2-deoxy-3-D-glycopyranosidase inhibitors

by GUCKIAN, Kevin M, ZHANG, Lei, LIN, Edward Yin Shiang, GENUNG, Nathan, GIANATASSIO, Ryan, VESSELS, Jeffrey, XIN, Zhili
Year of Publication 01.08.2024

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Patent

MORPHOLINYL, PIPERAZINYL, OXAZEPANYL AND DIAZEPANYL O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS

MORPHOLINYL, PIPERAZINYL, OXAZEPANYL AND DIAZEPANYL O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS

by GUCKIAN, Kevin, M, ZHANG, Lei, LIN, Edward Yin, Shiang, GENUNG, Nathan, GIANATASSIO, Ryan, VESSELS, Jeffrey, XIN, Zhili
Year of Publication 24.04.2024

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Patent

MORPHOLINYL, PIPERAZINYL, OXAZEPANYL AND DIAZEPANYL O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS

MORPHOLINYL, PIPERAZINYL, OXAZEPANYL AND DIAZEPANYL O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS

by GUCKIAN, Kevin, M, ZHANG, Lei, LIN, Edward Yin, Shiang, GENUNG, Nathan, GIANATASSIO, Ryan, VESSELS, Jeffrey, XIN, Zhili
Year of Publication 28.02.2024

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Patent

SPIROCYCLIC O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS

SPIROCYCLIC O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS

by Vessels, Jeffrey, Genung, Nathan, Guckian, Kevin M, Zhang, Lei, Xin, Zhili, Gianatassio, Ryan
Year of Publication 23.02.2023

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Patent

MORPHOLINYL, PIPERAZINYL, OXAZEPANYL AND DIAZEPANYL DERIVATIVES USEFUL AS O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS

MORPHOLINYL, PIPERAZINYL, OXAZEPANYL AND DIAZEPANYL DERIVATIVES USEFUL AS O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS

by GUCKIAN, Kevin, M, ZHANG, Lei, LIN, Edward Yin, Shiang, GENUNG, Nathan, GIANATASSIO, Ryan, VESSELS, Jeffrey, XIN, Zhili
Year of Publication 27.09.2023

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Patent

SPIROCYCLIC O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS

SPIROCYCLIC O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS

by GUCKIAN, Kevin, M, ZHANG, Lei, GENUNG, Nathan, GIANATASSIO, Ryan, VESSELS, Jeffrey, XIN, Zhili
Year of Publication 07.09.2022

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Patent

O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS

O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS

by GUCKIAN, Kevin M, ZHANG, Lei, LIN, Edward Yin Shiang, GENUNG, Nathan, GIANATASSIO, Ryan, VESSELS, Jeffrey, XIN, Zhili
Year of Publication 31.05.2023

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Patent

O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS

O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS

by Vessels, Jeffrey, Genung, Nathan, Guckian, Kevin M, Zhang, Lei, Xin, Zhili, Gianatassio, Ryan, Lin, Edward Yin Shiang
Year of Publication 20.04.2023

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Patent

TYROSINE KINASE 2 INHIBITORS AND USES THEREOF

TYROSINE KINASE 2 INHIBITORS AND USES THEREOF

by LEVIN, Tamara, LIN, Edward, MAITRA, Soma, GUCKIAN, Kevin, HELAL, Christopher, PATTAROPONG, Vatee, VESSELS, Jeffrey, VANDEVEER, Harold, LOPEZ DE TURISO, Felix, SCIABOLA, Simone, XIN, Zhili
Year of Publication 18.01.2024

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Patent

O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS

O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS

by GUCKIAN, Kevin M, ZHANG, Lei, LIN, Edward Yin Shiang, GENUNG, Nathan, GIANATASSIO, Ryan, VESSELS, Jeffrey, XIN, Zhili
Year of Publication 11.01.2023

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Patent

O-glycoprotein-2-acetamido-2-deoxy-3-D-glycopyranosidase inhibitors

O-glycoprotein-2-acetamido-2-deoxy-3-D-glycopyranosidase inhibitors

by Vessels, Jeffrey, Genung, Nathan, Guckian, Kevin M, Zhang, Lei, Xin, Zhili, Gianatassio, Ryan, Lin, Edward Yin Shiang
Year of Publication 04.10.2022

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Patent

PYRIMIDINE DERIVATIVES USEFUL AS RAF KINASE INHIBITORS

PYRIMIDINE DERIVATIVES USEFUL AS RAF KINASE INHIBITORS

by JONES JOHN HOWARD, TANAKA HIROKO, POWELL NOEL, RAIMUNDO BRIAN, WYNN THOMAS, GUAN BING, XIN ZHILI, COSSROW JENNIFER, FRANKLIN LIOYD, LUGOVSKOY ALEXEY, KUMARAVEL GNANASAMBANDAM, LANE BENJAMIN, CHEN WEIRONG, PENG HAIRUO, VESSELS JEFFREY, LITTKE ADAM
Year of Publication 29.03.2010

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Patent

Synthesis of [1,2,4]triazolo[1,5- a]pyrazines as adenosine A 2A receptor antagonists

Synthesis of [1,2,4]triazolo[1,5- a]pyrazines as adenosine A 2A receptor antagonists

by Dowling, James E., Vessels, Jeffrey T., Haque, Serajul, Chang, He Xi, van Vloten, Kurt, Kumaravel, Gnanasambandam, Engber, Thomas, Jin, Xiaowei, Phadke, Deepali, Wang, Joy, Ayyub, Eman, Petter, Russell C.
Published in Bioorganic & medicinal chemistry letters (2005)

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Journal Article

AZETIDINYL O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS

AZETIDINYL O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS

by Vessels, Jeffrey, Genung, Nathan, Guckian, Kevin M, Zhang, Lei, Xin, Zhili, Gianatassio, Ryan, Lin, Edward Yin Shiang
Year of Publication 18.08.2022

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Patent

BICYCLIC ETHER O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS

BICYCLIC ETHER O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS

by Vessels, Jeffrey, Genung, Nathan, Guckian, Kevin M, Zhang, Lei, Xin, Zhili, Gianatassio, Ryan, Lin, Edward Yin Shiang
Year of Publication 07.04.2022

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Patent

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