Sphingosine 1-phosphate receptor 1 and 3 are upregulated in multiple sclerosis lesions
Van Doorn, Ruben, Van Horssen, Jack, Verzijl, Dennis, Witte, Maarten, Ronken, Eric, Van Het Hof, Bert, Lakeman, Kim, Dijkstra, Christine D., Van Der Valk, Paul, Reijerkerk, Arie, Alewijnse, Astrid E., Peters, Stephan L. M., De Vries, Helga E.
Published in Glia (01.09.2010)
Published in Glia (01.09.2010)
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Journal Article
Human Cytomegalovirus-Encoded Chemokine Receptor US28 Promotes Tumorigenesis
Maussang, David, Verzijl, Dennis, van Walsum, Marijke, Leurs, Rob, Holl, Jens, Pleskoff, Olivier, Michel, Detlef, van Dongen, Guus A. M. S., Smit, Martine J.
Published in Proceedings of the National Academy of Sciences - PNAS (29.08.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (29.08.2006)
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Journal Article
Functionally biased modulation of A3 adenosine receptor agonist efficacy and potency by imidazoquinolinamine allosteric enhancers
Gao, Zhan-Guo, Verzijl, Dennis, Zweemer, Annelien, Ye, Kai, Göblyös, Anikó, IJzerman, Adriaan P., Jacobson, Kenneth A.
Published in Biochemical pharmacology (15.09.2011)
Published in Biochemical pharmacology (15.09.2011)
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Journal Article
An Fc-inert PD-L1×4-1BB bispecific antibody mediates potent anti-tumor immunity in mice by combining checkpoint inhibition and conditional 4-1BB co-stimulation
Muik, Alexander, Altintas, Isil, Gieseke, Friederike, Schoedel, Kristina B, Burm, Saskia M, Toker, Aras, Salcedo, Theodora W., Verzijl, Dennis, Eisel, David, Grunwitz, Christian, Kranz, Lena M, Vormehr, Mathias, Satijn, David P.E., Diken, Mustafa, Kreiter, Sebastian, Sasser, Kate, Ahmadi, Tahamtan, Türeci, Özlem, Breij, Esther C.W., Jure-Kunkel, Maria, Sahin, Ugur
Published in Oncoimmunology (2022)
Published in Oncoimmunology (2022)
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Journal Article
DuoBody-CD40x4-1BB induces dendritic-cell maturation and enhances T-cell activation through conditional CD40 and 4-1BB agonist activity
Muik, Alexander, Adams III, Homer C, Gieseke, Friederike, Altintas, Isil, Schoedel, Kristina B, Blum, Jordan M, Sänger, Bianca, Burm, Saskia M, Stanganello, Eliana, Verzijl, Dennis, Spires, Vanessa M, Vascotto, Fulvia, Toker, Aras, Quinkhardt, Juliane, Fereshteh, Mark, Diken, Mustafa, Satijn, David P E, Kreiter, Sebastian, Ahmadi, Tahamtan, Breij, Esther C W, Türeci, Özlem, Sasser, Kate, Sahin, Ugur, Jure-Kunkel, Maria
Published in Journal for immunotherapy of cancer (01.06.2022)
Published in Journal for immunotherapy of cancer (01.06.2022)
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Journal Article
Sphingosine-1-phosphate receptors: Zooming in on ligand-induced intracellular trafficking and its functional implications
Verzijl, Dennis, Academic Medical Center, Amsterdam, the Netherlands, Peters, Stephan L.M., Academic Medical Center, Amsterdam, the Netherlands, Alewijnse, Astrid E., Academic Medical Center, Amsterdam, the Netherlands
Published in Molecules and cells (01.02.2010)
Published in Molecules and cells (01.02.2010)
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Journal Article
863 In vitro and in vivo studies establish DuoBody®-CD3xB7H4 as a novel drug candidate for the treatment of solid cancers
Koopman, Louise, Vries, Laura Smits-de, Egerod, Frederikke Lihme, Wubben, Sebastiaan, Houtkamp, Mischa, Poot, Stefanie De, Paauwe, Madelon, Brink, Edward van den, Gorlani, Andrea, Verzijl, Dennis, Sasser, Kate, Breij, Esther
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
The Epstein-Barr Virus BILF1 Gene Encodes a G Protein-Coupled Receptor That Inhibits Phosphorylation of RNA-Dependent Protein Kinase
BEISSER, Patrick S, VERZIJL, Dennis, GRUIJTHUIJSEN, Yvonne K, BEUKEN, Erik, SMIT, Martine J, LEURS, Rob, BRUGGEMAN, Cathrien A, VINK, Cornelis
Published in Journal of Virology (01.01.2005)
Published in Journal of Virology (01.01.2005)
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Journal Article
Noncompetitive Antagonism and Inverse Agonism as Mechanism of Action of Nonpeptidergic Antagonists at Primate and Rodent CXCR3 Chemokine Receptors
Verzijl, Dennis, Storelli, Stefania, Scholten, Danny J, Bosch, Leontien, Reinhart, Todd A, Streblow, Daniel N, Tensen, Cornelis P, Fitzsimons, Carlos P, Zaman, Guido J R, Pease, James E, de Esch, Iwan J P, Smit, Martine J, Leurs, Rob
Published in The Journal of pharmacology and experimental therapeutics (01.05.2008)
Published in The Journal of pharmacology and experimental therapeutics (01.05.2008)
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Journal Article
Kaposi's Sarcoma-Associated Herpesvirus-Encoded G Protein-Coupled Receptor ORF74 Constitutively Activates p44/p42 MAPK and Akt via Gi and Phospholipase C-Dependent Signaling Pathways
Smit, Martine J., Verzijl, Dennis, Casarosa, Paola, Navis, Marjon, Timmerman, Henk, Leurs, Rob
Published in Journal of Virology (15.02.2002)
Published in Journal of Virology (15.02.2002)
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Journal Article
Constitutive Signaling of the Human Cytomegalovirus-encoded Receptor UL33 Differs from That of Its Rat Cytomegalovirus Homolog R33 by Promiscuous Activation of G Proteins of the Gq, Gi, and Gs Classes
Casarosa, Paola, Gruijthuijsen, Yvonne K., Michel, Detlef, Beisser, Patrick S., Holl, Jens, Fitzsimons, Carlos P., Verzijl, Dennis, Bruggeman, Cathrien A., Mertens, Thomas, Leurs, Rob, Vink, Cornelis, Smit, Martine J.
Published in The Journal of biological chemistry (12.12.2003)
Published in The Journal of biological chemistry (12.12.2003)
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Journal Article
Helix 8 of the Viral Chemokine Receptor ORF74 Directs Chemokine Binding
Verzijl, Dennis, Pardo, Leonardo, van Dijk, Marie, Gruijthuijsen, Yvonne K., Jongejan, Aldo, Timmerman, Henk, Nicholas, John, Schwarz, Mario, Murphy, Philip M., Leurs, Rob, Smit, Martine J.
Published in The Journal of biological chemistry (17.11.2006)
Published in The Journal of biological chemistry (17.11.2006)
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Journal Article
Chemokine-Directed Trafficking of Receptor Stimulus to Different G Proteins: Selective Inducible and Constitutive Signaling by Human Herpesvirus 6-Encoded Chemokine Receptor U51
Fitzsimons, Carlos P, Gompels, Ursula A, Verzijl, Dennis, Vischer, Henry F, Mattick, Claire, Leurs, Rob, Smit, Martine J
Published in Molecular pharmacology (01.03.2006)
Published in Molecular pharmacology (01.03.2006)
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Journal Article
Differential Activation of Murine Herpesvirus 68- and Kaposi's Sarcoma-Associated Herpesvirus-Encoded ORF74 G Protein-Coupled Receptors by Human and Murine Chemokines
VERZIJL, Dennis, FITZSIMONS, Carlos P, VAN DIJK, Marie, STEWART, James P, TIMMERMAN, Henk, SMIT, Martine J, LEURS, Rob
Published in Journal of Virology (01.04.2004)
Published in Journal of Virology (01.04.2004)
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Journal Article
Preclinical Characterization and Phase I Trial Results of a Bispecific Antibody Targeting PD-L1 and 4-1BB (GEN1046) in Patients with Advanced Refractory Solid Tumors
Muik, Alexander, Garralda, Elena, Altintas, Isil, Gieseke, Friederike, Geva, Ravit, Ben-Ami, Eytan, Maurice-Dror, Corinne, Calvo, Emiliano, LoRusso, Patricia M, Alonso, Guzman, Rodriguez-Ruiz, Maria E, Schoedel, Kristina B, Blum, Jordan M, Sänger, Bianca, Salcedo, Theodora W, Burm, Saskia M, Stanganello, Eliana, Verzijl, Dennis, Vascotto, Fulvia, Sette, Angelica, Quinkhardt, Juliane, Plantinga, Theo S, Toker, Aras, van den Brink, Edward N, Fereshteh, Mark, Diken, Mustafa, Satijn, David, Kreiter, Sebastian, Breij, Esther C W, Bajaj, Gaurav, Lagkadinou, Eleni, Sasser, Kate, Türeci, Özlem, Forssmann, Ulf, Ahmadi, Tahamtan, Şahin, Uğur, Jure-Kunkel, Maria, Melero, Ignacio
Published in Cancer discovery (02.05.2022)
Published in Cancer discovery (02.05.2022)
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Journal Article
Furin Is a Chemokine-modifying Enzyme
Hensbergen, Paul J., Verzijl, Dennis, Balog, Crina I.A., Dijkman, Remco, van der Schors, Roel C., van der Raaij-Helmer, Elizabeth M.H., van der Plas, Mariena J.A., Leurs, Rob, Deelder, André M., Smit, Martine J., Tensen, Cornelis P.
Published in The Journal of biological chemistry (02.04.2004)
Published in The Journal of biological chemistry (02.04.2004)
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Journal Article