The ALS-linked E102Q mutation in Sigma receptor-1 leads to ER stress-mediated defects in protein homeostasis and dysregulation of RNA-binding proteins
Dreser, Alice, Vollrath, Jan Tilmann, Sechi, Antonio, Johann, Sonja, Roos, Andreas, Yamoah, Alfred, Katona, Istvan, Bohlega, Saeed, Wiemuth, Dominik, Tian, Yuemin, Schmidt, Axel, Vervoorts, Jörg, Dohmen, Marc, Beyer, Cordian, Anink, Jasper, Aronica, Eleonora, Troost, Dirk, Weis, Joachim, Goswami, Anand
Published in Cell death and differentiation (01.10.2017)
Published in Cell death and differentiation (01.10.2017)
Get full text
Journal Article
regulation of SIRT2 function by cyclin-dependent kinases affects cell motility
Pandithage, Ruwin, Lilischkis, Richard, Harting, Kai, Wolf, Alexandra, Jedamzik, Britta, Lüscher-Firzlaff, Juliane, Vervoorts, Jörg, Lasonder, Edwin, Kremmer, Elisabeth, Knöll, Bernd, Lüscher, Bernhard
Published in The Journal of cell biology (10.03.2008)
Published in The Journal of cell biology (10.03.2008)
Get full text
Journal Article
AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy
Dohmen, Marc, Krieg, Sarah, Agalaridis, Georgios, Zhu, Xiaoqing, Shehata, Saifeldin N., Pfeiffenberger, Elisabeth, Amelang, Jan, Bütepage, Mareike, Buerova, Elena, Pfaff, Carolina M., Chanda, Dipanjan, Geley, Stephan, Preisinger, Christian, Sakamoto, Kei, Lüscher, Bernhard, Neumann, Dietbert, Vervoorts, Jörg
Published in Nature communications (25.02.2020)
Published in Nature communications (25.02.2020)
Get full text
Journal Article
The c-MYC oncoprotein, the NAMPT enzyme, SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop
Menssen, Antje, Hydbring, Per, Kapelle, Karsten, Vervoorts, Jörg, Diebold, Joachim, Lüscher, Bernhard, Larsson, Lars-Gunnar, Hermeking, Heiko
Published in Proceedings of the National Academy of Sciences - PNAS (24.01.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (24.01.2012)
Get full text
Journal Article
The Ins and Outs of MYC Regulation by Posttranslational Mechanisms
Vervoorts, Jörg, Lüscher-Firzlaff, Juliane, Lüscher, Bernhard
Published in The Journal of biological chemistry (17.11.2006)
Published in The Journal of biological chemistry (17.11.2006)
Get full text
Journal Article
Phosphorylation by Cdk2 is required for Myc to repress Ras-induced senescence in cotransformation
Hydbring, Per, Bahram, Fuad, Su, Yingtao, Tronnersjö, Susanna, Högstrand, Kari, von der Lehr, Natalie, Sharifi, Hamid Reza, Lilischkis, Richard, Hein, Nadine, Wu, Siqin, Vervoorts, Jörg, Henriksson, Marie, Grandien, Alf, Lüscher, Bernhard, Larsson, Lars-Gunnar
Published in Proceedings of the National Academy of Sciences - PNAS (05.01.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (05.01.2010)
Get full text
Journal Article
The interaction of MYC with the trithorax protein ASH2L promotes gene transcription by regulating H3K27 modification
Ullius, Andrea, Lüscher-Firzlaff, Juliane, Costa, Ivan G, Walsemann, Gesa, Forst, Alexandra H, Gusmao, Eduardo G, Kapelle, Karsten, Kleine, Henning, Kremmer, Elisabeth, Vervoorts, Jörg, Lüscher, Bernhard
Published in Nucleic acids research (17.06.2014)
Published in Nucleic acids research (17.06.2014)
Get full text
Journal Article
ING5 is phosphorylated by CDK2 and controls cell proliferation independently of p53
Linzen, Ulrike, Lilischkis, Richard, Pandithage, Ruwin, Schilling, Britta, Ullius, Andrea, Lüscher-Firzlaff, Juliane, Kremmer, Elisabeth, Lüscher, Bernhard, Vervoorts, Jörg
Published in PloS one (10.04.2015)
Published in PloS one (10.04.2015)
Get full text
Journal Article
PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation
MEI YU, SCHREEK, Sabine, MEHRAEIN, Yasmin, MERTSCHING, Jürgen, KRAFT, Regine, AUSTEN, Matthias, LÜSCHER-FIRZLAFF, Juliane, LÜSCHER, Bernhard, CERNI, Christa, SCHAMBERGER, Chantal, LESNIEWICZ, Krzysztof, POREBA, Elzbieta, VERVOORTS, Jörg, WALSEMANN, Gesa, GRÖTZINGER, Joachim, KREMMER, Elisabeth
Published in Oncogene (17.03.2005)
Published in Oncogene (17.03.2005)
Get full text
Journal Article
The Human Trithorax Protein hASH2 Functions as an Oncoprotein
LÜSCHER-FIRZLAFF, Juliane, GAWLISTA, Isabella, LILISCHKIS, Richard, CERNI, Christa, WELLMANN, Axel, LÜSCHER, Bernhard, VERVOORTS, Jörg, KAPELLE, Karsten, BRAUNSCHWEIG, Till, WALSEMANN, Gesa, RODGARKIA-SCHAMBERGER, Chantal, SCHUCHLAUTZ, Henning, DRESCHERS, Stephan, KREMMER, Elisabeth
Published in Cancer research (Chicago, Ill.) (01.02.2008)
Published in Cancer research (Chicago, Ill.) (01.02.2008)
Get full text
Journal Article
C-terminal phosphorylation controls the stability and function of p27kip1
Kossatz, Uta, Vervoorts, Jörg, Nickeleit, Irina, Sundberg, Holly A, Arthur, J Simon C, Manns, Michael P, Malek, Nisar P
Published in The EMBO journal (01.11.2006)
Published in The EMBO journal (01.11.2006)
Get full text
Journal Article
Stimulation of c-MYC transcriptional activity and acetylation by recruitment of the cofactor CBP
Vervoorts, Jörg, Lüscher-Firzlaff, Juliane M, Rottmann, Sabine, Lilischkis, Richard, Walsemann, Gesa, Dohmann, Karen, Austen, Matthias, Lüscher, Bernhard
Published in EMBO reports (01.05.2003)
Published in EMBO reports (01.05.2003)
Get full text
Journal Article
Structural prediction of the interaction of the tumor suppressor p27KIP1 with cyclin A/CDK2 identifies a novel catalytically relevant determinant
Li, Jinyu, Vervoorts, Jorg, Carloni, Paolo, Rossetti, Giulia, Luscher, Bernhard
Published in BMC bioinformatics (05.01.2017)
Published in BMC bioinformatics (05.01.2017)
Get full text
Journal Article
The β-catenin E3 ubiquitin ligase SIAH-1 is regulated by CSN5/JAB1 in CRC cells
Jumpertz, Sandra, Hennes, Thomas, Asare, Yaw, Vervoorts, Jörg, Bernhagen, Jürgen, Schütz, Anke K.
Published in Cellular signalling (01.09.2014)
Published in Cellular signalling (01.09.2014)
Get full text
Journal Article
Studying the Role of AMPK in Autophagy
Krieg, Sarah, Lüscher, Bernhard, Vervoorts, Jörg, Dohmen, Marc
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2018)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2018)
Get more information
Journal Article
Salmonella infection impacts host proteome thermal stability
Birk, Marlène S., Walch, Philipp, Baykara, Tarik, Sefried, Stephanie, Amelang, Jan, Buerova, Elena, Breuer, Ingrid, Vervoorts, Jörg, Typas, Athanasios, Savitski, Mikhail M., Mateus, André, Selkrig, Joel
Published in European journal of cell biology (01.12.2024)
Published in European journal of cell biology (01.12.2024)
Get full text
Journal Article
Digoxin inhibits development of hypoxic pulmonary hypertension in mice
Abud, Edsel M, Maylor, Julie, Undem, Clark, Punjabi, Arjun, Zaiman, Ari L, Myers, Allen C, Sylvester, J. T, Semenza, Gregg L, Shimoda, Larissa A
Published in Proceedings of the National Academy of Sciences - PNAS (24.01.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (24.01.2012)
Get full text
Journal Article
Tracking Effects of SIL1 Increase: Taking a Closer Look Beyond the Consequences of Elevated Expression Level
Labisch, Thomas, Buchkremer, Stephan, Phan, Vietxuan, Kollipara, Laxmikanth, Gatz, Christian, Lentz, Chris, Nolte, Kay, Vervoorts, Jörg, Coraspe, José Andrés González, Sickmann, Albert, Carr, Stephanie, Zahedi, René P., Weis, Joachim, Roos, Andreas
Published in Molecular neurobiology (01.03.2018)
Published in Molecular neurobiology (01.03.2018)
Get full text
Journal Article