Lessons learned: new insights on the role of cytokines in COVID-19
Buszko, Maja, Nita-Lazar, Aleksandra, Park, Jung-Hyun, Schwartzberg, Pamela L., Verthelyi, Daniela, Young, Howard A., Rosenberg, Amy S.
Published in Nature immunology (01.04.2021)
Published in Nature immunology (01.04.2021)
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Journal Article
Detection of innate immune response modulating impurities in therapeutic proteins
Haile, Lydia Asrat, Puig, Montserrat, Kelley-Baker, Logan, Verthelyi, Daniela
Published in PloS one (22.04.2015)
Published in PloS one (22.04.2015)
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Journal Article
Prior Exposure to Zika Virus Significantly Enhances Peak Dengue-2 Viremia in Rhesus Macaques
George, Jeffy, Valiant, William G., Mattapallil, Mary J., Walker, Michelle, Huang, Yan-Jang S., Vanlandingham, Dana L., Misamore, John, Greenhouse, Jack, Weiss, Deborah E., Verthelyi, Daniela, Higgs, Stephen, Andersen, Hanne, Lewis, Mark G., Mattapallil, Joseph J.
Published in Scientific reports (05.09.2017)
Published in Scientific reports (05.09.2017)
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Journal Article
Association of complement component 4 with neuroimmune abnormalities in the subventricular zone in schizophrenia and autism spectrum disorders
Mou, Ta-Chung M., Lane, Malcolm V., Ireland, Derek D.C., Verthelyi, Daniela, Tonelli, Leonardo H., Clark, Sarah M.
Published in Neurobiology of disease (15.10.2022)
Published in Neurobiology of disease (15.10.2022)
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Journal Article
Long-term persistence of infectious Zika virus: Inflammation and behavioral sequela in mice
Ireland, Derek D C, Manangeeswaran, Mohanraj, Lewkowicz, Aaron P, Engel, Kaliroi, Clark, Sarah M, Laniyan, Adelle, Sykes, Jacob, Lee, Ha-Na, McWilliams, Ian L, Kelley-Baker, Logan, Tonelli, Leonardo H, Verthelyi, Daniela
Published in PLoS pathogens (10.12.2020)
Published in PLoS pathogens (10.12.2020)
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Journal Article
Effect of Fatty Acid Composition in Polysorbate 80 on the Stability of Therapeutic Protein Formulations
Pegues, Melissa A., Szczepanek, Karol, Sheikh, Faruk, Thacker, Seth G., Aryal, Baikuntha, Ghorab, Mohamed K, Wolfgang, Steven, Donnelly, Raymond P., Verthelyi, Daniela, Rao, V. Ashutosh
Published in Pharmaceutical research (01.11.2021)
Published in Pharmaceutical research (01.11.2021)
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Journal Article
Multiplexed Gene Expression as a Characterization of Bioactivity for Interferon Beta (IFN-β) Biosimilar Candidates: Impact of Innate Immune Response Modulating Impurities (IIRMIs)
Mufarrege, Eduardo F., Haile, Lydia A., Etcheverrigaray, Marina, Verthelyi, Daniela I.
Published in The AAPS journal (01.03.2019)
Published in The AAPS journal (01.03.2019)
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Journal Article
Glycosylation, Hypogammaglobulinemia, and Resistance to Viral Infections
Sadat, Mohammed A, Moir, Susan, Chun, Tae-Wook, Lusso, Paolo, Kaplan, Gerardo, Wolfe, Lynne, Memoli, Matthew J, He, Miao, Vega, Hugo, Kim, Leo J.Y, Huang, Yan, Hussein, Nadia, Nievas, Elma, Mitchell, Raquel, Garofalo, Mary, Louie, Aaron, Ireland, Derek C, Grunes, Claire, Cimbro, Raffaello, Patel, Vyomesh, Holzapfel, Genevieve, Salahuddin, Daniel, Bristol, Tyler, Adams, David, Marciano, Beatriz E, Hegde, Madhuri, Li, Yuxing, Calvo, Katherine R, Stoddard, Jennifer, Justement, J. Shawn, Jacques, Jerome, Long Priel, Debra A, Murray, Danielle, Sun, Peter, Kuhns, Douglas B, Boerkoel, Cornelius F, Chiorini, John A, Di Pasquale, Giovanni, Verthelyi, Daniela, Rosenzweig, Sergio D
Published in The New England journal of medicine (24.04.2014)
Published in The New England journal of medicine (24.04.2014)
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Journal Article
Neutralizing antibodies to therapeutic enzymes: considerations for testing, prevention and treatment
Rosenberg, Amy, Wang, Jinhai, Lozier, Jay, Johnson, Gibbes, Kirshner, Susan, Verthelyi, Daniela, Pariser, Anne, Shores, Elizabeth
Published in Nature biotechnology (01.08.2008)
Published in Nature biotechnology (01.08.2008)
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Journal Article
An In Vitro Assessment of Immunostimulatory Responses to Ten Model Innate Immune Response Modulating Impurities (IIRMIs) and Peptide Drug Product, Teriparatide
Holley, Claire K, Cedrone, Edward, Donohue, Duncan, Neun, Barry W, Verthelyi, Daniela, Pang, Eric S, Dobrovolskaia, Marina A
Published in Molecules (Basel, Switzerland) (09.12.2021)
Published in Molecules (Basel, Switzerland) (09.12.2021)
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Journal Article
CpG ODN D35 improves the response to abbreviated low-dose pentavalent antimonial treatment in non-human primate model of cutaneous leishmaniasis
Thacker, Seth G, McWilliams, Ian L, Bonnet, Beatrice, Halie, Lydia, Beaucage, Serge, Rachuri, Swaksha, Dey, Ranadhir, Duncan, Robert, Modabber, Farrokh, Robinson, Stephen, Bilbe, Graeme, Arana, Byron, Verthelyi, Daniela
Published in PLoS neglected tropical diseases (01.02.2020)
Published in PLoS neglected tropical diseases (01.02.2020)
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Journal Article
Assessing the immunogenicity risk of salmon calcitonin peptide impurities using in silico and in vitro methods
Roberts, Brian J, Mattei, Aimee E, Howard, Kristina E, Weaver, James L, Liu, Hao, Lelias, Sandra, Martin, William D, Verthelyi, Daniela, Pang, Eric, Edwards, Katie J, De Groot, Anne S
Published in Frontiers in pharmacology (09.08.2024)
Published in Frontiers in pharmacology (09.08.2024)
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Journal Article
Use of CpG oligodeoxynucleotides as immune adjuvants
Klinman, Dennis M., Currie, Debra, Gursel, Ihsan, Verthelyi, Daniela
Published in Immunological reviews (01.06.2004)
Published in Immunological reviews (01.06.2004)
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Journal Article
Detection of innate immune response modulating impurities (IIRMI) in therapeutic peptides and proteins: Impact of excipients
Thacker, Seth G., Her, Cheng, Kelley-Baker, Logan, Ireland, Derek D C., Manangeeswaran, Mohanraj, Pang, Eric S., Verthelyi, Daniela
Published in Frontiers in immunology (06.09.2022)
Published in Frontiers in immunology (06.09.2022)
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Journal Article
Expression profiles of human interferon‐alpha and interferon‐lambda subtypes are ligand‐ and cell‐dependent
Hillyer, Philippa, Mane, Viraj P, Schramm, Lynnsie M, Puig, Montserrat, Verthelyi, Daniela, Chen, Aaron, Zhao, Zeng, Navarro, Maria B, Kirschman, Kevin D, Bykadi, Srikant, Jubin, Ronald G, Rabin, Ronald L
Published in Immunology and cell biology (01.09.2012)
Published in Immunology and cell biology (01.09.2012)
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