Antibody-mediated phagocytosis contributes to the anti-tumor activity of the therapeutic antibody daratumumab in lymphoma and multiple myeloma
Overdijk, Marije B, Verploegen, Sandra, Bögels, Marijn, van Egmond, Marjolein, van Bueren, Jeroen J Lammerts, Mutis, Tuna, Groen, Richard WJ, Breij, Esther, Martens, Anton CM, Bleeker, Wim K, Parren, Paul WHI
Published in mAbs (04.03.2015)
Published in mAbs (04.03.2015)
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A Novel Platform for the Potentiation of Therapeutic Antibodies Based on Antigen-Dependent Formation of IgG Hexamers at the Cell Surface
de Jong, Rob N, Beurskens, Frank J, Verploegen, Sandra, Strumane, Kristin, van Kampen, Muriel D, Voorhorst, Marleen, Horstman, Wendy, Engelberts, Patrick J, Oostindie, Simone C, Wang, Guanbo, Heck, Albert J R, Schuurman, Janine, Parren, Paul W H I
Published in PLoS biology (01.01.2016)
Published in PLoS biology (01.01.2016)
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Efficient generation of stable bispecific IgG1 by controlled Fab-arm exchange
Labrijn, Aran F, Meesters, Joyce I, de Goeij, Bart E C G, van den Bremer, Ewald T J, Neijssen, Joost, van Kampen, Muriel D, Strumane, Kristin, Verploegen, Sandra, Kundu, Amitava, Gramer, Michael J, van Berkel, Patrick H C, van de Winkel, Jan G J, Schuurman, Janine, Parren, Paul W H I
Published in Proceedings of the National Academy of Sciences - PNAS (26.03.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (26.03.2013)
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DuoBody-CD3xCD20 induces potent T-cell-mediated killing of malignant B cells in preclinical models and provides opportunities for subcutaneous dosing
Engelberts, Patrick J., Hiemstra, Ida H., de Jong, Bart, Schuurhuis, Danita H., Meesters, Joyce, Beltran Hernandez, Irati, Oostindie, Simone C., Neijssen, Joost, van den Brink, Edward N., Horbach, G. Jean, Verploegen, Sandra, Labrijn, Aran F., Salcedo, Theodora, Schuurman, Janine, Parren, Paul W.H.I, Breij, Esther C.W.
Published in EBioMedicine (01.02.2020)
Published in EBioMedicine (01.02.2020)
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Efficient Generation of Bispecific Murine Antibodies for Pre-Clinical Investigations in Syngeneic Rodent Models
Labrijn, Aran F, Meesters, Joyce I, Bunce, Matthew, Armstrong, Anthony A, Somani, Sandeep, Nesspor, Tom C, Chiu, Mark L, Altintaş, Işil, Verploegen, Sandra, Schuurman, Janine, Parren, Paul W H I
Published in Scientific reports (30.05.2017)
Published in Scientific reports (30.05.2017)
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Protein kinase B (c-akt) regulates hematopoietic lineage choice decisions during myelopoiesis
Buitenhuis, Miranda, Verhagen, Liesbeth P., van Deutekom, Hanneke W.M., Castor, Anders, Verploegen, Sandra, Koenderman, Leo, Jacobsen, Sten-Eirik W., Coffer, Paul J.
Published in Blood (01.01.2008)
Published in Blood (01.01.2008)
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Characterization of the role of CaMKI-like kinase (CKLiK) in human granulocyte function
Verploegen, Sandra, Ulfman, Laurien, van Deutekom, Hanneke W.M., van Aalst, Corneli, Honing, Henk, Lammers, Jan-Willem J., Koenderman, Leo, Coffer, Paul J.
Published in Blood (01.08.2005)
Published in Blood (01.08.2005)
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Identification and characterization of CKLiK, a novel granulocyte Ca++/calmodulin-dependent kinase
Verploegen, Sandra, Lammers, Jan-Willem J., Koenderman, Leo, Coffer, Paul J.
Published in Blood (01.11.2000)
Published in Blood (01.11.2000)
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CD3-Bispecific Antibody Therapy Turns Solid Tumors into Inflammatory Sites but Does Not Install Protective Memory
Benonisson, Hreinn, Altıntaş, Işıl, Sluijter, Marjolein, Verploegen, Sandra, Labrijn, Aran F, Schuurhuis, Danita H, Houtkamp, Mischa A, Verbeek, J Sjef, Schuurman, Janine, van Hall, Thorbald
Published in Molecular cancer therapeutics (01.02.2019)
Published in Molecular cancer therapeutics (01.02.2019)
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An Antibody-Drug Conjugate That Targets Tissue Factor Exhibits Potent Therapeutic Activity against a Broad Range of Solid Tumors
BREIJ, Esther C. W, DE GOEIJ, Bart E. C. G, PARREN, Paul W. H. I, VERPLOEGEN, Sandra, SCHUURHUIS, Danita H, AMIRKHOSRAVI, Ali, FRANCIS, John, MILLER, Vibeke Breinholt, HOUTKAMP, Mischa, BLEEKER, Wim K, SATIJN, David
Published in Cancer research (Chicago, Ill.) (15.02.2014)
Published in Cancer research (Chicago, Ill.) (15.02.2014)
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Logic-gated antibody pairs that selectively act on cells co-expressing two antigens
Oostindie, Simone C, Rinaldi, Derek A, Zom, Gijs G, Wester, Michael J, Paulet, Desiree, Al-Tamimi, Kusai, van der Meijden, Els, Scheick, Jennifer R, Wilpshaar, Tessa, de Jong, Bart, Hoff-van den Broek, Marloes, Grattan, Rachel M, Oosterhoff, Janita J, Vignau, Julie, Verploegen, Sandra, Boross, Peter, Beurskens, Frank J, Lidke, Diane S, Schuurman, Janine, de Jong, Rob N
Published in Nature biotechnology (01.10.2022)
Published in Nature biotechnology (01.10.2022)
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Journal Article
Identification and characterization of CKLiK, a novel granulocyte Ca++/calmodulin-dependent kinase
Verploegen, Sandra, Lammers, Jan-Willem J., Koenderman, Leo, Coffer, Paul J.
Published in Blood (01.11.2000)
Published in Blood (01.11.2000)
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Abstract 221: Tisotumab vedotin induces anti-tumor activity through MMAE-mediated, Fc-mediated, and Fab-mediated effector functions in vitro
Alley, Stephen C., Harris, Jeffrey R., Cao, Anthony, Heuvel, Elke Gresnigt-van den, Velayudhan, Jyoti, Satijn, David, Verploegen, Sandra, Dominguez, Teresa, Breij, Esther C.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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IgG1 Fc HUMAN IGG1 FC REGION VARIANTS AND USES THEREOF
SCHUURMAN JANINE, DE JONG ROB N, BEURSKENS FRANK, LABRIJN ARAN FRANK, VERPLOEGEN SANDRA, PARREN PAUL
Year of Publication 13.08.2024
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Year of Publication 13.08.2024
Patent
Abstract 5669: Establishment of a human CD3ε transgenic mouse model to assess anti-tumor efficacy of human T-cell-redirecting bispecific antibodies
Yang, Mengmeng, Zhang, Mingkun, Verploegen, Sandra, Engelberts, Patrick, Zhang, Yuxi, Zheng, Lei, Zhu, Keyi, An, Annie Xiaoyu, Ju, Cunxiang, Zhao, Jing, Gao, Xiang, Shi, Qian, Ouyang, Davy Xuesong
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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CD3 CD20 Bispecific Antibodies against CD3 and CD20
BREIJ ESTHER, SCHUURMAN JANINE, ALTINTAS ISIL, VAN DEN BRINK EDWARD, ENGELBERTS PATRICK, VERPLOEGEN SANDRA, RADEMAKER RIK, RADERSMA RIEMKE VAN DIJKHUIZEN, PARREN PAUL, SATIJN DAVID
Year of Publication 13.05.2024
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Year of Publication 13.05.2024
Patent
백금-기반 작용제와 항-조직 인자 항체-약물 접합체의 조합을 사용하여 암을 치료하는 방법
RANGWALA RESHMA A, BREIJ ESTHER C W, NICACIO LEONARDO V, VERPLOEGEN SANDRA, ABIDOYE OYEWALE O
Year of Publication 07.07.2022
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Year of Publication 07.07.2022
Patent
Anti-galactose-α-1,3-galactose IgE from allergic patients does not bind α-galactosylated glycans on intact therapeutic antibody Fc domains
Parren, Paul W H I, van Bueren, Jeroen J Lammerts, Rispens, Theo, Verploegen, Sandra, van der Palen-Merkus, Tjitske, Turinsky, Andrei L, Stapel, Steven, Workman, Lisa J, James, Hayley, van Berkel, Patrick H C, van de Winkel, Jan G J, Platts-Mills, Thomas A E
Published in Nature biotechnology (01.07.2011)
Published in Nature biotechnology (01.07.2011)
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A human leptin mutant induces weight gain in normal mice
Verploegen, Sandra A.B.W., Plaetinck, Geert, Devos, René, Van der Heyden, José, Guisez, Yves
Published in FEBS letters (24.03.1997)
Published in FEBS letters (24.03.1997)
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