Search Results - "VERNIER JEAN-MICHEL" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Pharmacological Characterization and Identification of Amino Acids Involved in the Positive Modulation of Metabotropic Glutamate Receptor Subtype 2

Pharmacological Characterization and Identification of Amino Acids Involved in the Positive Modulation of Metabotropic Glutamate Receptor Subtype 2

by Schaffhauser, Hervé, Rowe, Blake A, Morales, Sylvia, Chavez-Noriega, Laura E, Yin, Ruoyuan, Jachec, Christine, Rao, Sara P, Bain, Gretchen, Pinkerton, Anthony B, Vernier, Jean-Michel, Bristow, Linda J, Varney, Mark A, Daggett, Lorrie P
Published in Molecular pharmacology (01.10.2003)

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Journal Article

Entrectinib, a Pan-TRK, ROS1, and ALK Inhibitor with Activity in Multiple Molecularly Defined Cancer Indications

Entrectinib, a Pan-TRK, ROS1, and ALK Inhibitor with Activity in Multiple Molecularly Defined Cancer Indications

by Ardini, Elena, Menichincheri, Maria, Banfi, Patrizia, Bosotti, Roberta, De Ponti, Cristina, Pulci, Romana, Ballinari, Dario, Ciomei, Marina, Texido, Gemma, Degrassi, Anna, Avanzi, Nilla, Amboldi, Nadia, Saccardo, Maria Beatrice, Casero, Daniele, Orsini, Paolo, Bandiera, Tiziano, Mologni, Luca, Anderson, David, Wei, Ge, Harris, Jason, Vernier, Jean-Michel, Li, Gang, Felder, Eduard, Donati, Daniele, Isacchi, Antonella, Pesenti, Enrico, Magnaghi, Paola, Galvani, Arturo
Published in Molecular cancer therapeutics (01.04.2016)

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Journal Article

Group II mGlu Receptor Activation Suppresses Norepinephrine Release in the Ventral Hippocampus and Locomotor Responses to Acute Ketamine Challenge

Group II mGlu Receptor Activation Suppresses Norepinephrine Release in the Ventral Hippocampus and Locomotor Responses to Acute Ketamine Challenge

by LORRAIN, Daniel S, SCHAFFHAUSER, Hervé, VERNIER, Jean-Michel, BRISTOW, Linda J, CAMPBELL, Una C, BACCEI, Christopher S, CORREA, Lucia D, ROWE, Blake, RODRIGUEZ, Dana E, ANDERSON, Jeffery J, VARNEY, Mark A, PINKERTON, Anthony B
Published in Neuropsychopharmacology (01.09.2003)

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Journal Article

RDEA119/BAY 869766: A Potent, Selective, Allosteric Inhibitor of MEK1/2 for the Treatment of Cancer

RDEA119/BAY 869766: A Potent, Selective, Allosteric Inhibitor of MEK1/2 for the Treatment of Cancer

by IVERSON, Cory, LARSON, Gary, HAMATAKE, Robert, MINER, Jeffrey N, QUART, Barry, LAI, Chon, YEH, Li-Tain, DADSON, Claudia, WEINGARTEN, Paul, APPLEBY, Todd, VO, Todd, MADERNA, Andreas, VERNIER, Jean-Michel
Published in Cancer research (Chicago, Ill.) (01.09.2009)

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Journal Article

Structure-Based Design and Synthesis of Potent and Selective KRAS G12D Inhibitors

Structure-Based Design and Synthesis of Potent and Selective KRAS G12D Inhibitors

by Cheng, Hengmiao, Li, Puhui, Chen, Ping, Irimia, Adriana, Bae, Jae Hyun, Brooun, Alexei, Fagan, Patrick, Lam, Richard, Lin, Bingzhen, Zhang, Jingchuan, Zhan, Xuejun, Wu, Xu, Xie, Nan, Chiang, Gary, Shoemaker, Robert, Vernier, Jean-Michel
Published in ACS medicinal chemistry letters (12.10.2023)

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Journal Article

INDOLINONE COMPOUNDS AND USES THEREOF

INDOLINONE COMPOUNDS AND USES THEREOF

by VERNIER JEAN MICHEL
Year of Publication 14.06.2017

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Patent

황 함유 헤테로방향족 트리사이클릭 KRAS 억제제

황 함유 헤테로방향족 트리사이클릭 KRAS 억제제

by CHEN PING, ISLEY NICHOLAS A, VERNIER JEAN MICHEL, GONZALEZ LOPEZ MARCOS, FENG JUN, JONES BENJAMIN
Year of Publication 29.02.2024

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Patent

3환식 피리돈 및 피리미돈

3환식 피리돈 및 피리미돈

by CHEN PING, ISLEY NICHOLAS A, VERNIER JEAN MICHEL, FENG JUN, GONZALEZ LOPEZ MARCOS, JONES BENJAMIN
Year of Publication 27.06.2023

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Patent

Dipyridyl amides: potent metabotropic glutamate subtype 5 (mGlu5) receptor antagonists

Dipyridyl amides: potent metabotropic glutamate subtype 5 (mGlu5) receptor antagonists

by Bonnefous, Céline, Vernier, Jean-Michel, Hutchinson, John H., Chung, Janice, Reyes-Manalo, Grace, Kamenecka, Theodore
Published in Bioorganic & medicinal chemistry letters (15.02.2005)

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Journal Article

Diaryl substituted pyrazoles as potent CCR2 receptor antagonists

Diaryl substituted pyrazoles as potent CCR2 receptor antagonists

by Pinkerton, Anthony B., Huang, Dehua, Cube, Rowena V., Hutchinson, John H., Struthers, Mary, Ayala, Julia M., Vicario, Pasquale P., Patel, Sima R., Wisniewski, Thomas, DeMartino, Julie A., Vernier, Jean-Michel
Published in Bioorganic & medicinal chemistry letters (01.02.2007)

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Journal Article

Phenyl-tetrazolyl Acetophenones: Discovery of Positive Allosteric Potentiatiors for the Metabotropic Glutamate 2 Receptor

Phenyl-tetrazolyl Acetophenones: Discovery of Positive Allosteric Potentiatiors for the Metabotropic Glutamate 2 Receptor

by Pinkerton, Anthony B, Vernier, Jean-Michel, Schaffhauser, Hervé, Rowe, Blake A, Campbell, Una C, Rodriguez, Dana E, Lorrain, Daniel S, Baccei, Christopher S, Daggett, Lorrie P, Bristow, Linda J
Published in Journal of medicinal chemistry (26.08.2004)

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Journal Article

Biphenyl-indanones: Allosteric potentiators of the metabotropic glutamate subtype 2 receptor

Biphenyl-indanones: Allosteric potentiators of the metabotropic glutamate subtype 2 receptor

by Bonnefous, Céline, Vernier, Jean-Michel, Hutchinson, John H., Gardner, Michael F., Cramer, Merryl, James, Joyce K., Rowe, Blake A., Daggett, Lorrie P., Schaffhauser, Hervé, Kamenecka, Theodore M.
Published in Bioorganic & medicinal chemistry letters (01.10.2005)

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Journal Article

Benzazoles as allosteric potentiators of metabotropic glutamate receptor 2 (mGluR2): Efficacy in an animal model for schizophrenia

Benzazoles as allosteric potentiators of metabotropic glutamate receptor 2 (mGluR2): Efficacy in an animal model for schizophrenia

by Govek, Steven P., Bonnefous, Celine, Hutchinson, John H., Kamenecka, Theodore, McQuiston, Jeffrey, Pracitto, Richard, Zhao, Lucy X., Gardner, Michael F., James, Joyce K., Daggett, Lorrie P., Rowe, Blake A., Schaffhauser, Hervé, Bristow, Linda J., Campbell, Una C., Rodriguez, Dana E., Vernier, Jean-Michel
Published in Bioorganic & medicinal chemistry letters (15.09.2005)

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Journal Article

Allosteric potentiators of the metabotropic glutamate receptor 2 (mGlu2). Part 3: Identification and biological activity of indanone containing mGlu2 receptor potentiators

Allosteric potentiators of the metabotropic glutamate receptor 2 (mGlu2). Part 3: Identification and biological activity of indanone containing mGlu2 receptor potentiators

by Pinkerton, Anthony B., Cube, Rowena V., Hutchinson, John H., James, Joyce K., Gardner, Michael F., Rowe, Blake A., Schaffhauser, Hervé, Rodriguez, Dana E., Campbell, Una C., Daggett, Lorrie P., Vernier, Jean-Michel
Published in Bioorganic & medicinal chemistry letters (15.03.2005)

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Journal Article

3-(2-Ethoxy-4-{4-[3-hydroxy-2-methyl-4-(3-methylbutanoyl)phenoxy]butoxy}phenyl)propanoic acid: a brain penetrant allosteric potentiator at the metabotropic glutamate receptor 2 (mGluR2)

3-(2-Ethoxy-4-{4-[3-hydroxy-2-methyl-4-(3-methylbutanoyl)phenoxy]butoxy}phenyl)propanoic acid: a brain penetrant allosteric potentiator at the metabotropic glutamate receptor 2 (mGluR2)

by Cube, Rowena V., Vernier, Jean-Michel, Hutchinson, John H., Gardner, Michael F., James, Joyce K., Rowe, Blake A., Schaffhauser, Herve, Daggett, Lorrie, Pinkerton, Anthony B.
Published in Bioorganic & medicinal chemistry letters (02.05.2005)

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Journal Article

6-Benzylamino 4-oxo-1,4-dihydro-1,8-naphthyridines and 4-oxo-1,4-dihydroquinolines as HIV integrase inhibitors

6-Benzylamino 4-oxo-1,4-dihydro-1,8-naphthyridines and 4-oxo-1,4-dihydroquinolines as HIV integrase inhibitors

by Nagasawa, Johnny Y., Song, Jenny, Chen, Huanming, Kim, Hong-Woo, Blazel, Julie, Ouk, Samedy, Groschel, Bettina, Borges, Virginia, Ong, Voon, Yeh, Li-Tain, Girardet, Jean-Luc, Vernier, Jean-Michel, Raney, Anneke K., Pinkerton, Anthony B.
Published in Bioorganic & medicinal chemistry letters (15.01.2011)

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Journal Article

Allosteric potentiators of the metabotropic glutamate receptor 2 (mGlu2). Part 1: Identification and synthesis of phenyl-tetrazolyl acetophenones

Allosteric potentiators of the metabotropic glutamate receptor 2 (mGlu2). Part 1: Identification and synthesis of phenyl-tetrazolyl acetophenones

by PINKERTON, Anthony B, CUBE, Rowena V, HUTCHINSON, John H, ROWE, Blake A, SCHAFFHAUSER, Hervé, XIUMIN ZHAO, DAGGETT, Lorrie P, VERNIER, Jean-Michel
Published in Bioorganic & medicinal chemistry letters (01.11.2004)

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Journal Article

Discovery of novel modulators of metabotropic glutamate receptor subtype-5

Discovery of novel modulators of metabotropic glutamate receptor subtype-5

by Wang, Bowei, Vernier, Jean-Michel, Rao, Sara, Chung, Janice, Anderson, Jeffery J, Brodkin, Jesse D, Jiang, Xiaohui, Gardner, Michael F, Yang, Xiaoqing, Munoz, Benito
Published in Bioorganic & medicinal chemistry (02.01.2004)

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Journal Article

Allosteric potentiators of the metabotropic glutamate receptor 2 (mGlu2). Part 2: 4-Thiopyridyl acetophenones as non-tetrazole containing mGlu2 receptor potentiators

Allosteric potentiators of the metabotropic glutamate receptor 2 (mGlu2). Part 2: 4-Thiopyridyl acetophenones as non-tetrazole containing mGlu2 receptor potentiators

by Pinkerton, Anthony B., Cube, Rowena V., Hutchinson, John H., James, Joyce K., Gardner, Michael F., Schaffhauser, Hervé, Rowe, Blake A., Daggett, Lorrie P., Vernier, Jean-Michel
Published in Bioorganic & medicinal chemistry letters (06.12.2004)

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Journal Article

NAPHTHYRIDINE DERIVATIVES AS POTASSIUM CHANNEL MODULATORS

NAPHTHYRIDINE DERIVATIVES AS POTASSIUM CHANNEL MODULATORS

by VERNIER JEAN MICHEL
Year of Publication 23.06.2010

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Patent

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