TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis
Sun, Tianhe, Huang, Zhiyu, Liang, Wei-Ching, Yin, Jianping, Lin, Wei Yu, Wu, Jia, Vernes, Jean-Michel, Lutman, Jeff, Caplazi, Patrick, Jeet, Surinder, Wong, Tiffany, Wong, Manda, DePianto, Daryle J, Morshead, Katrina B, Sun, Kai-Hui, Modrusan, Zora, Vander Heiden, Jason A, Abbas, Alexander R, Zhang, Hua, Xu, Min, N'Diaye, Elsa-Noah, Roose-Girma, Meron, Wolters, Paul J, Yadav, Rajbharan, Sukumaran, Siddharth, Ghilardi, Nico, Corpuz, Racquel, Emson, Claire, Meng, Y Gloria, Ramalingam, Thirumalai R, Lupardus, Patrick, Brightbill, Hans D, Seshasayee, Dhaya, Wu, Yan, Arron, Joseph R
Published in Science translational medicine (04.08.2021)
Published in Science translational medicine (04.08.2021)
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Journal Article
A targeted boost-and-sort immunization strategy using Escherichia coli BamA identifies rare growth inhibitory antibodies
Vij, Rajesh, Lin, Zhonghua, Chiang, Nancy, Vernes, Jean-Michel, Storek, Kelly M., Park, Summer, Chan, Joyce, Meng, Y. Gloria, Comps-Agrar, Laetitia, Luan, Peng, Lee, Sophia, Schneider, Kellen, Bevers, Jack, Zilberleyb, Inna, Tam, Christine, Koth, Christopher M., Xu, Min, Gill, Avinash, Auerbach, Marcy R., Smith, Peter A., Rutherford, Steven T., Nakamura, Gerald, Seshasayee, Dhaya, Payandeh, Jian, Koerber, James T.
Published in Scientific reports (08.05.2018)
Published in Scientific reports (08.05.2018)
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Journal Article
Massive antibody discovery used to probe structure-function relationships of the essential outer membrane protein LptD
Storek, Kelly M, Chan, Joyce, Vij, Rajesh, Chiang, Nancy, Lin, Zhonghua, Bevers, 3rd, Jack, Koth, Christopher M, Vernes, Jean-Michel, Meng, Y Gloria, Yin, JianPing, Wallweber, Heidi, Dalmas, Olivier, Shriver, Stephanie, Tam, Christine, Schneider, Kellen, Seshasayee, Dhaya, Nakamura, Gerald, Smith, Peter A, Payandeh, Jian, Koerber, James T, Comps-Agrar, Laetitia, Rutherford, Steven T
Published in eLife (25.06.2019)
Published in eLife (25.06.2019)
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Journal Article
A neutralizing anti-gH/gL monoclonal antibody is protective in the guinea pig model of congenital CMV infection
Auerbach, Marcy R, Yan, Donghong, Vij, Rajesh, Hongo, Jo-Anne, Nakamura, Gerald, Vernes, Jean-Michel, Meng, Y Gloria, Lein, Samantha, Chan, Pamela, Ross, Jed, Carano, Richard, Deng, Rong, Lewin-Koh, Nicholas, Xu, Min, Feierbach, Becket
Published in PLoS pathogens (01.04.2014)
Published in PLoS pathogens (01.04.2014)
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Journal Article
TMEFF2 is a PDGF-AA binding protein with methylation-associated gene silencing in multiple cancer types including glioma
Lin, Kui, Taylor, Jr, James R, Wu, Thomas D, Gutierrez, Johnny, Elliott, J Michael, Vernes, Jean-Michel, Koeppen, Hartmut, Phillips, Heidi S, de Sauvage, Frederic J, Meng, Y Gloria
Published in PloS one (29.04.2011)
Published in PloS one (29.04.2011)
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Journal Article
Association between HER-2/neu and Vascular Endothelial Growth Factor Expression Predicts Clinical Outcome in Primary Breast Cancer Patients
KONECNY, Gottfried E, MENG, Y. Gloria, BERYT, Malgorzata, HEPP, Hermann, SLAMON, Dennis J, PEGRAM, Mark D, UNTCH, Michael, WANG, He-Jing, BAUERFEIND, Ingo, EPSTEIN, Melinda, STIEBER, Petra, VERNES, Jean-Michel, GUTIERREZ, Johnny, KYU HONG
Published in Clinical cancer research (01.03.2004)
Published in Clinical cancer research (01.03.2004)
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Journal Article
Real-time immuno-polymerase chain reaction in a 384-well format: Detection of vascular endothelial growth factor and epidermal growth factor-like domain 7
Zhang, Jianhuan, Vernes, Jean-Michel, Ni, Jennifer, Nelson, Christopher, Wong, Anne, Chen, Steven T., Asundi, Aarati, Vandlen, Richard, Meng, Y. Gloria
Published in Analytical biochemistry (15.10.2014)
Published in Analytical biochemistry (15.10.2014)
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Journal Article
Complex formation of anti‐VEGF‐C with VEGF‐C released during blood coagulation resulted in an artifact in its serum pharmacokinetics
Bumbaca Yadav, Daniela, Reyes, Arthur E., Gupta, Priyanka, Vernes, Jean‐Michel, Meng, Y. Gloria, Schweiger, Michelle G., Stainton, Shannon L., Fuh, Germaine, Fielder, Paul J., Kamath, Amrita V., Shen, Ben‐Quan
Published in Pharmacology research & perspectives (01.04.2020)
Published in Pharmacology research & perspectives (01.04.2020)
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Journal Article
An interleukin-17–mediated paracrine network promotes tumor resistance to anti-angiogenic therapy
Chung, Alicia S, Wu, Xiumin, Zhuang, Guanglei, Ngu, Hai, Kasman, Ian, Zhang, Jianhuan, Vernes, Jean-Michel, Jiang, Zhaoshi, Meng, Y Gloria, Peale, Franklin V, Ouyang, Wenjun, Ferrara, Napoleone
Published in Nature medicine (01.09.2013)
Published in Nature medicine (01.09.2013)
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Journal Article
Real-time quantification of antibody–short interfering RNA conjugate in serum by antigen capture reverse transcription–polymerase chain reaction
Tan, Martha, Vernes, Jean-Michel, Chan, Joyce, Cuellar, Trinna L., Asundi, Aarati, Nelson, Christopher, Yip, Victor, Shen, Ben, Vandlen, Richard, Siebel, Christian, Meng, Y. Gloria
Published in Analytical biochemistry (15.11.2012)
Published in Analytical biochemistry (15.11.2012)
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Journal Article
Effector-attenuating Substitutions That Maintain Antibody Stability and Reduce Toxicity in Mice
Lo, Megan, Kim, Hok Seon, Tong, Raymond K., Bainbridge, Travis W., Vernes, Jean-Michel, Zhang, Yin, Lin, Yuwen Linda, Chung, Shan, Dennis, Mark S., Zuchero, Y. Joy Yu, Watts, Ryan J., Couch, Jessica A., Meng, Y. Gloria, Atwal, Jasvinder K., Brezski, Randall J., Spiess, Christoph, Ernst, James A.
Published in The Journal of biological chemistry (03.03.2017)
Published in The Journal of biological chemistry (03.03.2017)
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Journal Article
A Potent Pan-TGFβ Neutralizing Monoclonal Antibody Elicits Cardiovascular Toxicity in Mice and Cynomolgus Monkeys
Mitra, Mayur S, Lancaster, Karla, Adedeji, Adeyemi O, Palanisamy, Gopinath S, Dave, Rutwij A, Zhong, Fiona, Holdren, Matthew S, Turley, Shannon J, Liang, Wei-Ching, Wu, Yan, Meng, Y Gloria, Vernes, Jean-Michel, Schutten, Melissa M
Published in Toxicological sciences (01.05.2020)
Published in Toxicological sciences (01.05.2020)
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Journal Article
An Fcγ Receptor-Dependent Mechanism Drives Antibody-Mediated Target-Receptor Signaling in Cancer Cells
Wilson, Nicholas S., Yang, Becky, Yang, Annie, Loeser, Stefanie, Marsters, Scot, Lawrence, David, Li, Yun, Pitti, Robert, Totpal, Klara, Yee, Sharon, Ross, Sarajane, Vernes, Jean-Michel, Lu, Yanmei, Adams, Cam, Offringa, Rienk, Kelley, Bob, Hymowitz, Sarah, Daniel, Dylan, Meng, Gloria, Ashkenazi, Avi
Published in Cancer cell (18.01.2011)
Published in Cancer cell (18.01.2011)
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Journal Article
Reproducible quantification of IgG uptake at endogenous and overexpressed FcRn levels at pH 7.4: Comparison of a wild type IgG and a stronger FcRn binding variant
Zhang, Jianhuan, Vernes, Jean-Michel, Wen, Xiaohui, Oh, Ernest, Scales, Suzie J., Meng, Y. Gloria
Published in Journal of immunological methods (01.05.2020)
Published in Journal of immunological methods (01.05.2020)
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Journal Article
PlGF Blockade Does Not Inhibit Angiogenesis during Primary Tumor Growth
Bais, Carlos, Wu, Xiumin, Yao, Jenny, Yang, Suya, Crawford, Yongping, McCutcheon, Krista, Tan, Christine, Kolumam, Ganesh, Vernes, Jean-Michel, Eastham-Anderson, Jeffrey, Haughney, Peter, Kowanetz, Marcin, Hagenbeek, Thijs, Kasman, Ian, Reslan, Hani Bou, Ross, Jed, Van Bruggen, Nick, Carano, Richard A.D., Meng, Yu-Ju Gloria, Hongo, Jo-Anne, Stephan, Jean- Philippe, Shibuya, Masabumi, Ferrara, Napoleone
Published in Cell (02.04.2010)
Published in Cell (02.04.2010)
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Journal Article
Evading pre-existing anti-hinge antibody binding by hinge engineering
Kim, Hok Seon, Kim, Ingrid, Zheng, Linda, Vernes, Jean-Michel, Meng, Y Gloria, Spiess, Christoph
Published in mAbs (16.11.2016)
Published in mAbs (16.11.2016)
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Journal Article
Detection and Quantification of VEGF Isoforms by ELISA
Vernes, Jean-Michel, Meng, Y Gloria
Published in Methods in molecular biology (Clifton, N.J.) (2015)
Published in Methods in molecular biology (Clifton, N.J.) (2015)
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Journal Article
A therapeutic anti-VEGF antibody with increased potency independent of pharmacokinetic half-life
Yeung, Yik Andy, Wu, Xiumin, Reyes, 2nd, Arthur E, Vernes, Jean-Michel, Lien, Samantha, Lowe, John, Maia, Mauricio, Forrest, William F, Meng, Y Gloria, Damico, Lisa A, Ferrara, Napoleone, Lowman, Henry B
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Journal Article
Sustained Brown Fat Stimulation and Insulin Sensitization by a Humanized Bispecific Antibody Agonist for Fibroblast Growth Factor Receptor 1/βKlotho Complex
Kolumam, Ganesh, Chen, Mark Z., Tong, Raymond, Zavala-Solorio, Jose, Kates, Lance, van Bruggen, Nicholas, Ross, Jed, Wyatt, Shelby K., Gandham, Vineela D., Carano, Richard A.D., Dunshee, Diana Ronai, Wu, Ai-Luen, Haley, Benjamin, Anderson, Keith, Warming, Søren, Rairdan, Xin Y., Lewin-Koh, Nicholas, Zhang, Yingnan, Gutierrez, Johnny, Baruch, Amos, Gelzleichter, Thomas R., Stevens, Dale, Rajan, Sharmila, Bainbridge, Travis W., Vernes, Jean-Michel, Meng, Y. Gloria, Ziai, James, Soriano, Robert H., Brauer, Matthew J., Chen, Yongmei, Stawicki, Scott, Kim, Hok Seon, Comps-Agrar, Laëtitia, Luis, Elizabeth, Spiess, Christoph, Wu, Yan, Ernst, James A., McGuinness, Owen P., Peterson, Andrew S., Sonoda, Junichiro
Published in EBioMedicine (01.07.2015)
Published in EBioMedicine (01.07.2015)
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Journal Article
Increased in vivo effector function of human IgG4 isotype antibodies through afucosylation
Gong, Qian, Hazen, Meredith, Marshall, Brett, Crowell, Susan R, Ou, Qinglin, Wong, Athena W, Phung, Wilson, Vernes, Jean-Michel, Meng, Y Gloria, Tejada, Max, Andersen, Dana, Kelley, Robert F
Published in mAbs (17.08.2016)
Published in mAbs (17.08.2016)
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