PBPK in Preterm and Term Neonates: A Review
Michelet, Robin, Bocxlaer, Jan Van, Vermeulen, An
Published in Current pharmaceutical design (01.01.2017)
Published in Current pharmaceutical design (01.01.2017)
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Journal Article
Pharmacokinetics and pharmacodynamics across infusion rates of intravenously administered nipocalimab: results of a phase 1, placebo-controlled study
Leu, Jocelyn H, Vermeulen, An, Abbes, Claudia, Arroyo, Santiago, Denney, William S, Ling, Leona E
Published in Frontiers in neuroscience (01.02.2024)
Published in Frontiers in neuroscience (01.02.2024)
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Journal Article
Acute balenine supplementation in humans as a natural carnosinase-resistant alternative to carnosine
de Jager, Sarah, Vermeulen, An, De Baere, Siegrid, Van der Stede, Thibaux, Lievens, Eline, Croubels, Siska, Jäger, Ralf, Purpura, Martin, Bourgois, Jan G., Derave, Wim
Published in Scientific reports (20.04.2023)
Published in Scientific reports (20.04.2023)
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Journal Article
The Use of Population Pharmacokinetics to Extrapolate Food Effects from Human Adults and Beagle Dogs to the Pediatric Population Illustrated with Paracetamol as a Test Case
Gasthuys, Elke, Sandra, Louis, Statelova, Marina, Vertzoni, Maria, Vermeulen, An
Published in Pharmaceuticals (Basel, Switzerland) (28.12.2023)
Published in Pharmaceuticals (Basel, Switzerland) (28.12.2023)
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Journal Article
Possible Mechanisms of the Interplay between Drugs and Mycotoxins-Is There a Possible Impact?
Lootens, Orphélie, Vermeulen, An, Croubels, Siska, De Saeger, Sarah, Van Bocxlaer, Jan, De Boevre, Marthe
Published in Toxins (01.12.2022)
Published in Toxins (01.12.2022)
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Journal Article
Exploring the Impact of Efavirenz on Aflatoxin B1 Metabolism: Insights from a Physiologically Based Pharmacokinetic Model and a Human Liver Microsome Study
Lootens, Orphélie, De Boevre, Marthe, Gasthuys, Elke, De Saeger, Sarah, Van Bocxlaer, Jan, Vermeulen, An
Published in Toxins (01.06.2024)
Published in Toxins (01.06.2024)
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Journal Article
Unravelling the pharmacokinetics of aflatoxin B1: In vitro determination of Michaelis–Menten constants, intrinsic clearance and the metabolic contribution of CYP1A2 and CYP3A4 in pooled human liver microsomes
Lootens, Orphélie, De Boevre, Marthe, Gasthuys, Elke, Van Bocxlaer, Jan, Vermeulen, An, De Saeger, Sarah
Published in Frontiers in microbiology (29.08.2022)
Published in Frontiers in microbiology (29.08.2022)
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Journal Article
Correlation between Prostate-Specific Antigen Kinetics and Overall Survival in Abiraterone Acetate-Treated Castration-Resistant Prostate Cancer Patients
Xu, Xu S, Ryan, Charles J, Stuyckens, Kim, Smith, Matthew R, Saad, Fred, Griffin, Thomas W, Park, Youn C, Yu, Margaret K, Vermeulen, An, Poggesi, Italo, Nandy, Partha
Published in Clinical cancer research (15.07.2015)
Published in Clinical cancer research (15.07.2015)
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Journal Article
A systems pharmacology model for inflammatory bowel disease
Balbas-Martinez, Violeta, Ruiz-Cerdá, Leire, Irurzun-Arana, Itziar, González-García, Ignacio, Vermeulen, An, Gómez-Mantilla, José David, Trocóniz, Iñaki F
Published in PloS one (07.03.2018)
Published in PloS one (07.03.2018)
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Model‐based meta‐analysis to quantify the effects of short interfering RNA therapeutics on hepatitis B surface antigen turnover in hepatitis B‐infected mice
Sandra, Louis, T'jollyn, Huybrecht, Vermeulen, An, Ackaert, Oliver, Perez‐Ruixo, Juan‐Jose
Published in CPT: pharmacometrics and systems pharmacology (01.05.2024)
Published in CPT: pharmacometrics and systems pharmacology (01.05.2024)
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Journal Article
A Generic Multi-Compartmental CNS Distribution Model Structure for 9 Drugs Allows Prediction of Human Brain Target Site Concentrations
Yamamoto, Yumi, Välitalo, Pyry A., van den Berg, Dirk-Jan, Hartman, Robin, van den Brink, Willem, Wong, Yin Cheong, Huntjens, Dymphy R., Proost, Johannes H., Vermeulen, An, Krauwinkel, Walter, Bakshi, Suruchi, Aranzana-Climent, Vincent, Marchand, Sandrine, Dahyot-Fizelier, Claire, Couet, William, Danhof, Meindert, van Hasselt, Johan G. C., de Lange, Elizabeth C. M.
Published in Pharmaceutical research (01.02.2017)
Published in Pharmaceutical research (01.02.2017)
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Journal Article
Minimal Physiologically-Based Pharmacokinetic (mPBPK) Metamodeling of Target Engagement in Skin Informs Anti-IL17A Drug Development in Psoriasis
Ayyar, Vivaswath S, Lee, Jong Bong, Wang, Weirong, Pryor, Meghan, Zhuang, Yanli, Wilde, Thomas, Vermeulen, An
Published in Frontiers in pharmacology (25.04.2022)
Published in Frontiers in pharmacology (25.04.2022)
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Journal Article
Phase I study of intraperitoneal aerosolized nanoparticle albumin based paclitaxel (NAB-PTX) for unresectable peritoneal metastases
Ceelen, Wim, Sandra, Louis, de Sande, Leen Van, Graversen, Martin, Mortensen, Michael Bau, Vermeulen, An, Gasthuys, Elke, Reynders, Dries, Cosyns, Sarah, Hoorens, Anne, Willaert, Wouter
Published in EBioMedicine (01.08.2022)
Published in EBioMedicine (01.08.2022)
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Journal Article
Heterogeneous photocatalysis of moxifloxacin: Identification of degradation products and determination of residual antibacterial activity
Van Doorslaer, Xander, Demeestere, Kristof, Heynderickx, Philippe M., Caussyn, Marieke, Van Langenhove, Herman, Devlieghere, Frank, Vermeulen, An, Dewulf, Jo
Published in Applied catalysis. B, Environmental (17.07.2013)
Published in Applied catalysis. B, Environmental (17.07.2013)
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Journal Article
Predicting Drug Concentration‐Time Profiles in Multiple CNS Compartments Using a Comprehensive Physiologically‐Based Pharmacokinetic Model
Yamamoto, Yumi, Välitalo, Pyry A., Huntjens, Dymphy R., Proost, Johannes H., Vermeulen, An, Krauwinkel, Walter, Beukers, Margot W., van den Berg, Dirk‐Jan, Hartman, Robin, Wong, Yin Cheong, Danhof, Meindert, van Hasselt, John G. C., de Lange, Elizabeth C. M.
Published in CPT: pharmacometrics and systems pharmacology (01.11.2017)
Published in CPT: pharmacometrics and systems pharmacology (01.11.2017)
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Journal Article
Altered intravenous drug disposition in people living with cystic fibrosis: A meta‐analysis integrating top‐down and bottom‐up data
De Sutter, Pieter‐Jan, Van Haeverbeke, Maxime, Van Braeckel, Eva, Van Biervliet, Stephanie, Van Bocxlaer, Jan, Vermeulen, An, Gasthuys, Elke
Published in CPT: pharmacometrics and systems pharmacology (01.08.2022)
Published in CPT: pharmacometrics and systems pharmacology (01.08.2022)
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