EZH2 Is Required for Germinal Center Formation and Somatic EZH2 Mutations Promote Lymphoid Transformation
Béguelin, Wendy, Popovic, Relja, Teater, Matt, Jiang, Yanwen, Bunting, Karen L., Rosen, Monica, Shen, Hao, Yang, Shao Ning, Wang, Ling, Ezponda, Teresa, Martinez-Garcia, Eva, Zhang, Haikuo, Zheng, Yupeng, Verma, Sharad K., McCabe, Michael T., Ott, Heidi M., Van Aller, Glenn S., Kruger, Ryan G., Liu, Yan, McHugh, Charles F., Scott, David W., Chung, Young Rock, Kelleher, Neil, Shaknovich, Rita, Creasy, Caretha L., Gascoyne, Randy D., Wong, Kwok-Kin, Cerchietti, Leandro, Levine, Ross L., Abdel-Wahab, Omar, Licht, Jonathan D., Elemento, Olivier, Melnick, Ari M.
Published in Cancer cell (13.05.2013)
Published in Cancer cell (13.05.2013)
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A687V EZH2 is a driver of histone H3 lysine 27 (H3K27) hypertrimethylation
Ott, Heidi M, Graves, Alan P, Pappalardi, Melissa B, Huddleston, Michael, Halsey, Wendy S, Hughes, Ashley M, Groy, Arthur, Dul, Edward, Jiang, Yong, Bai, Yuchen, Annan, Roland, Verma, Sharad K, Knight, Steven D, Kruger, Ryan G, Dhanak, Dashyant, Schwartz, Benjamin, Tummino, Peter J, Creasy, Caretha L, McCabe, Michael T
Published in Molecular cancer therapeutics (01.12.2014)
Published in Molecular cancer therapeutics (01.12.2014)
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Funding community collaboration to develop effective therapies for neurofibromatosis type 1 tumors
La Rosa, Salvatore, Browder, Vidya, Bakker, Annette C, Blakeley, Jaishri O, Verma, Sharad K, Wong, Ling M, Morris, Jill, Bora, Naba
Published in EMBO molecular medicine (09.01.2020)
Published in EMBO molecular medicine (09.01.2020)
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Long Residence Time Inhibition of EZH2 in Activated Polycomb Repressive Complex 2
Van Aller, Glenn S, Pappalardi, Melissa Baker, Ott, Heidi M, Diaz, Elsie, Brandt, Martin, Schwartz, Benjamin J, Miller, William H, Dhanak, Dashyant, McCabe, Michael T, Verma, Sharad K, Creasy, Caretha L, Tummino, Peter J, Kruger, Ryan G
Published in ACS chemical biology (21.03.2014)
Published in ACS chemical biology (21.03.2014)
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EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations
McCabe, Michael T., Ott, Heidi M., Ganji, Gopinath, Korenchuk, Susan, Thompson, Christine, Van Aller, Glenn S., Liu, Yan, Graves, Alan P., III, Anthony Della Pietra, Diaz, Elsie, LaFrance, Louis V., Mellinger, Mark, Duquenne, Celine, Tian, Xinrong, Kruger, Ryan G., McHugh, Charles F., Brandt, Martin, Miller, William H., Dhanak, Dashyant, Verma, Sharad K., Tummino, Peter J., Creasy, Caretha L.
Published in Nature (London) (06.12.2012)
Published in Nature (London) (06.12.2012)
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Cutaneous neurofibromas: Current clinical and pathologic issues
Ortonne, Nicolas, Wolkenstein, Pierre, Blakeley, Jaishri O, Korf, Bruce, Plotkin, Scott R, Riccardi, Vincent M, Miller, Douglas C, Huson, Susan, Peltonen, Juha, Rosenberg, Andrew, Carroll, Steven L, Verma, Sharad K, Mautner, Victor, Upadhyaya, Meena, Stemmer-Rachamimov, Anat
Published in Neurology (10.07.2018)
Published in Neurology (10.07.2018)
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New approaches for challenging therapeutic targets
Sharma, Karlie R., Malik, Abir, Roof, Rebecca A., Boyce, Jim P., Verma, Sharad K.
Published in Drug discovery today (01.04.2024)
Published in Drug discovery today (01.04.2024)
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Considerations for development of therapies for cutaneous neurofibroma
Verma, Sharad K, Riccardi, Vincent M, Plotkin, Scott R, Weinberg, Hubert, Anderson, R Rox, Blakeley, Jaishri O, Jarnagin, Kurt, Lee, James
Published in Neurology (10.07.2018)
Published in Neurology (10.07.2018)
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The biology of cutaneous neurofibromas: Consensus recommendations for setting research priorities
Brosseau, Jean-Philippe, Pichard, Dominique C, Legius, Eric H, Wolkenstein, Pierre, Lavker, Robert M, Blakeley, Jaishri O, Riccardi, Vincent M, Verma, Sharad K, Brownell, Isaac, Le, Lu Q
Published in Neurology (10.07.2018)
Published in Neurology (10.07.2018)
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Journal Article
Clinical trial design for cutaneous neurofibromas
Cannon, Ashley, Jarnagin, Kurt, Korf, Bruce, Widemann, Brigitte C, Casey, Denise, Ko, Hon-Sum, Blakeley, Jaishri O, Verma, Sharad K, Pichard, Dominique C
Published in Neurology (10.07.2018)
Published in Neurology (10.07.2018)
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Journal Article
Creating a comprehensive research strategy for cutaneous neurofibromas
Blakeley, Jaishri O, Wolkenstein, Pierre, Widemann, Brigitte C, Lee, James, Le, Lu Q, Jackson, Rhonda, Stathis, Marigo, Verma, Sharad K
Published in Neurology (10.07.2018)
Published in Neurology (10.07.2018)
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Journal Article
Identification of Potent, Selective, Cell-Active Inhibitors of the Histone Lysine Methyltransferase EZH2
Verma, Sharad K, Tian, Xinrong, LaFrance, Louis V, Duquenne, Céline, Suarez, Dominic P, Newlander, Kenneth A, Romeril, Stuart P, Burgess, Joelle L, Grant, Seth W, Brackley, James A, Graves, Alan P, Scherzer, Daryl A, Shu, Art, Thompson, Christine, Ott, Heidi M, Aller, Glenn S. Van, Machutta, Carl A, Diaz, Elsie, Jiang, Yong, Johnson, Neil W, Knight, Steven D, Kruger, Ryan G, McCabe, Michael T, Dhanak, Dashyant, Tummino, Peter J, Creasy, Caretha L, Miller, William H
Published in ACS medicinal chemistry letters (13.12.2012)
Published in ACS medicinal chemistry letters (13.12.2012)
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Journal Article
Development and validation of reagents and assays for EZH2 peptide and nucleosome high-throughput screens
Diaz, Elsie, Machutta, Carl A, Chen, Stephanie, Jiang, Yong, Nixon, Christopher, Hofmann, Glenn, Key, Danielle, Sweitzer, Sharon, Patel, Mehul, Wu, Zining, Creasy, Caretha L, Kruger, Ryan G, LaFrance, Louis, Verma, Sharad K, Pappalardi, Melissa B, Le, Baochau, Van Aller, Glenn S, McCabe, Michael T, Tummino, Peter J, Pope, Andrew J, Thrall, Sara H, Schwartz, Benjamin, Brandt, Martin
Published in Journal of biomolecular screening (01.12.2012)
Published in Journal of biomolecular screening (01.12.2012)
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Assessing interobserver variability and accuracy in the histological diagnosis and classification of cutaneous neurofibromass
Ortonne, Nicolas, Carroll, Steven L, Rodriguez, Fausto J, Miller, Douglas C, Nazarian, Rosalynn M, Blakeley, Jaishri O, Madaj, Zachary B, Verma, Sharad K, Stemmer-Rachamimov, Anat
Published in Neuro-oncology advances (01.07.2020)
Published in Neuro-oncology advances (01.07.2020)
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