Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides
Iwamoto, Naoki, Butler, David C D, Svrzikapa, Nenad, Mohapatra, Susovan, Zlatev, Ivan, Sah, Dinah W Y, Meena, Standley, Stephany M, Lu, Genliang, Apponi, Luciano H, Frank-Kamenetsky, Maria, Zhang, Jason Jingxin, Vargeese, Chandra, Verdine, Gregory L
Published in Nature biotechnology (01.09.2017)
Published in Nature biotechnology (01.09.2017)
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Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin
Palchaudhuri, Rahul, Saez, Borja, Hoggatt, Jonathan, Schajnovitz, Amir, Sykes, David B, Tate, Tiffany A, Czechowicz, Agnieszka, Kfoury, Youmna, Ruchika, Fnu, Rossi, Derrick J, Verdine, Gregory L, Mansour, Michael K, Scadden, David T
Published in Nature biotechnology (01.07.2016)
Published in Nature biotechnology (01.07.2016)
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Structural Basis for the Lesion-scanning Mechanism of the MutY DNA Glycosylase
Wang, Lan, Chakravarthy, Srinivas, Verdine, Gregory L.
Published in The Journal of biological chemistry (24.03.2017)
Published in The Journal of biological chemistry (24.03.2017)
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Direct inhibition of the NOTCH transcription factor complex
MOELLERING, Raymond E, CORNEJO, Melanie, DAVIS, Tina N, DEL BIANCO, Cristina, ASTER, Jon C, BLACKLOW, Stephen C, KUNG, Andrew L, GARY GILLILAND, D, VERDINE, Gregory L, BRADNER, James E
Published in Nature (London) (12.11.2009)
Published in Nature (London) (12.11.2009)
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The trajectory of intrahelical lesion recognition and extrusion by the human 8-oxoguanine DNA glycosylase
Shigdel, Uddhav K., Ovchinnikov, Victor, Lee, Seung-Joo, Shih, Jenny A., Karplus, Martin, Nam, Kwangho, Verdine, Gregory L.
Published in Nature communications (07.09.2020)
Published in Nature communications (07.09.2020)
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Regulation of MLL1 H3K4 methyltransferase activity by its core components
Roeder, Robert G, Dou, Yali, Milne, Thomas A, Ruthenburg, Alexander J, Lee, Seunghee, Lee, Jae Woon, Verdine, Gregory L, Allis, C David
Published in Nature structural & molecular biology (01.08.2006)
Published in Nature structural & molecular biology (01.08.2006)
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Stapled peptide inhibitors of RAB25 target context-specific phenotypes in cancer
Mitra, Shreya, Montgomery, Jeffrey E, Kolar, Matthew J, Li, Gang, Jeong, Kang J, Peng, Bo, Verdine, Gregory L, Mills, Gordon B, Moellering, Raymond E
Published in Nature communications (22.09.2017)
Published in Nature communications (22.09.2017)
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Recognition and reprogramming of E3 ubiquitin ligase surfaces by α-helical peptides
Tokareva, Olena S, Li, Kunhua, Travaline, Tara L, Thomson, Ty M, Swiecicki, Jean-Marie, Moussa, Mahmoud, Ramirez, Jessica D, Litchman, Sean, Verdine, Gregory L, McGee, John H
Published in Nature communications (01.11.2023)
Published in Nature communications (01.11.2023)
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Nonspecifically bound proteins spin while diffusing along DNA
Xie, X Sunney, Bagchi, Biman, Blainey, Paul C, Kou, S C, Mangel, Walter F, Verdine, Gregory L, Luo, Guobin
Published in Nature structural & molecular biology (01.12.2009)
Published in Nature structural & molecular biology (01.12.2009)
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Mirror-image ligand discovery enabled by single-shot fast-flow synthesis of D-proteins
Callahan, Alex J, Gandhesiri, Satish, Travaline, Tara L, Reja, Rahi M, Lozano Salazar, Lia, Hanna, Stephanie, Lee, Yen-Chun, Li, Kunhua, Tokareva, Olena S, Swiecicki, Jean-Marie, Loas, Andrei, Verdine, Gregory L, McGee, John H, Pentelute, Bradley L
Published in Nature communications (28.02.2024)
Published in Nature communications (28.02.2024)
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A Base-Excision DNA-Repair Protein Finds Intrahelical Lesion Bases by Fast Sliding in Contact with DNA
Blainey, Paul C., van Oijen, Antoine M., Banerjee, Anirban, Verdine, Gregory L., Xie, X. Sunney
Published in Proceedings of the National Academy of Sciences - PNAS (11.04.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (11.04.2006)
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Encounter and extrusion of an intrahelical lesion by a DNA repair enzyme
Karplus, Martin, Verdine, Gregory L, Qi, Yan, Spong, Marie C, Nam, Kwangho, Banerjee, Anirban, Jiralerspong, Sao
Published in Nature (London) (10.12.2009)
Published in Nature (London) (10.12.2009)
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IMPDH2 Is an Intracellular Target of the Cyclophilin A and Sanglifehrin A Complex
Pua, Khian Hong, Stiles, Dylan T., Sowa, Mathew E., Verdine, Gregory L.
Published in Cell reports (Cambridge) (10.01.2017)
Published in Cell reports (Cambridge) (10.01.2017)
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Journal Article
Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA
BANERJEE, Anirban, WEI YANG, KARPLUS, Martin, VERDINE, Gregory L
Published in Nature (London) (31.03.2005)
Published in Nature (London) (31.03.2005)
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Activation of Apoptosis in vivo by a Hydrocarbon-Stapled BH3 Helix
Walensky, Loren D., Kung, Andrew L., Escher, Iris, Malia, Thomas J., Barbuto, Scott, Wright, Renee D., Wagner, Gerhard, Verdine, Gregory L., Korsmeyer, Stanley J.
Published in Science (American Association for the Advancement of Science) (03.09.2004)
Published in Science (American Association for the Advancement of Science) (03.09.2004)
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Stereochemical effects of all-hydrocarbon tethers in i, i+4 stapled peptides
Kim, Young-Woo, Verdine, Gregory L.
Published in Bioorganic & medicinal chemistry letters (01.05.2009)
Published in Bioorganic & medicinal chemistry letters (01.05.2009)
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Journal Article
Structure of a DNA Glycosylase Searching for Lesions
Banerjee, Anirban, Santos, Webster L, Verdine, Gregory L
Published in Science (American Association for the Advancement of Science) (24.02.2006)
Published in Science (American Association for the Advancement of Science) (24.02.2006)
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