Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides
Iwamoto, Naoki, Butler, David C D, Svrzikapa, Nenad, Mohapatra, Susovan, Zlatev, Ivan, Sah, Dinah W Y, Meena, Standley, Stephany M, Lu, Genliang, Apponi, Luciano H, Frank-Kamenetsky, Maria, Zhang, Jason Jingxin, Vargeese, Chandra, Verdine, Gregory L
Published in Nature biotechnology (01.09.2017)
Published in Nature biotechnology (01.09.2017)
Get full text
Journal Article
Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin
Palchaudhuri, Rahul, Saez, Borja, Hoggatt, Jonathan, Schajnovitz, Amir, Sykes, David B, Tate, Tiffany A, Czechowicz, Agnieszka, Kfoury, Youmna, Ruchika, Fnu, Rossi, Derrick J, Verdine, Gregory L, Mansour, Michael K, Scadden, David T
Published in Nature biotechnology (01.07.2016)
Published in Nature biotechnology (01.07.2016)
Get full text
Journal Article
Structural Basis for the Lesion-scanning Mechanism of the MutY DNA Glycosylase
Wang, Lan, Chakravarthy, Srinivas, Verdine, Gregory L.
Published in The Journal of biological chemistry (24.03.2017)
Published in The Journal of biological chemistry (24.03.2017)
Get full text
Journal Article
Direct inhibition of the NOTCH transcription factor complex
MOELLERING, Raymond E, CORNEJO, Melanie, DAVIS, Tina N, DEL BIANCO, Cristina, ASTER, Jon C, BLACKLOW, Stephen C, KUNG, Andrew L, GARY GILLILAND, D, VERDINE, Gregory L, BRADNER, James E
Published in Nature (London) (12.11.2009)
Published in Nature (London) (12.11.2009)
Get full text
Journal Article
Structure of the Stapled p53 Peptide Bound to Mdm2
Baek, Sohee, Kutchukian, Peter S, Verdine, Gregory L, Huber, Robert, Holak, Tad A, Lee, Ki Won, Popowicz, Grzegorz M
Published in Journal of the American Chemical Society (11.01.2012)
Published in Journal of the American Chemical Society (11.01.2012)
Get full text
Journal Article
Targeted β‐catenin ubiquitination and degradation by multifunctional stapled peptides
Wang, Xiaofeng, Dong, Liuli, Cheng, Jiongjia, Verdine, Gregory L., Lin, Aijun, Chu, Qian
Published in Journal of peptide science (01.07.2022)
Published in Journal of peptide science (01.07.2022)
Get full text
Journal Article
The trajectory of intrahelical lesion recognition and extrusion by the human 8-oxoguanine DNA glycosylase
Shigdel, Uddhav K., Ovchinnikov, Victor, Lee, Seung-Joo, Shih, Jenny A., Karplus, Martin, Nam, Kwangho, Verdine, Gregory L.
Published in Nature communications (07.09.2020)
Published in Nature communications (07.09.2020)
Get full text
Journal Article
Regulation of MLL1 H3K4 methyltransferase activity by its core components
Roeder, Robert G, Dou, Yali, Milne, Thomas A, Ruthenburg, Alexander J, Lee, Seunghee, Lee, Jae Woon, Verdine, Gregory L, Allis, C David
Published in Nature structural & molecular biology (01.08.2006)
Published in Nature structural & molecular biology (01.08.2006)
Get full text
Journal Article
Stapled peptide inhibitors of RAB25 target context-specific phenotypes in cancer
Mitra, Shreya, Montgomery, Jeffrey E, Kolar, Matthew J, Li, Gang, Jeong, Kang J, Peng, Bo, Verdine, Gregory L, Mills, Gordon B, Moellering, Raymond E
Published in Nature communications (22.09.2017)
Published in Nature communications (22.09.2017)
Get full text
Journal Article
Nonspecifically bound proteins spin while diffusing along DNA
Xie, X Sunney, Bagchi, Biman, Blainey, Paul C, Kou, S C, Mangel, Walter F, Verdine, Gregory L, Luo, Guobin
Published in Nature structural & molecular biology (01.12.2009)
Published in Nature structural & molecular biology (01.12.2009)
Get full text
Journal Article
Recognition and reprogramming of E3 ubiquitin ligase surfaces by α-helical peptides
Tokareva, Olena S, Li, Kunhua, Travaline, Tara L, Thomson, Ty M, Swiecicki, Jean-Marie, Moussa, Mahmoud, Ramirez, Jessica D, Litchman, Sean, Verdine, Gregory L, McGee, John H
Published in Nature communications (01.11.2023)
Published in Nature communications (01.11.2023)
Get full text
Journal Article
Mirror-image ligand discovery enabled by single-shot fast-flow synthesis of D-proteins
Callahan, Alex J, Gandhesiri, Satish, Travaline, Tara L, Reja, Rahi M, Lozano Salazar, Lia, Hanna, Stephanie, Lee, Yen-Chun, Li, Kunhua, Tokareva, Olena S, Swiecicki, Jean-Marie, Loas, Andrei, Verdine, Gregory L, McGee, John H, Pentelute, Bradley L
Published in Nature communications (28.02.2024)
Published in Nature communications (28.02.2024)
Get full text
Journal Article
Stitched α‑Helical Peptides via Bis Ring-Closing Metathesis
Hilinski, Gerard J, Kim, Young-Woo, Hong, Jooyeon, Kutchukian, Peter S, Crenshaw, Charisse M, Berkovitch, Shaunna S, Chang, Andrew, Ham, Sihyun, Verdine, Gregory L
Published in Journal of the American Chemical Society (03.09.2014)
Published in Journal of the American Chemical Society (03.09.2014)
Get full text
Journal Article