Oncostatin M: Risks and Benefits of a Novel Therapeutic Target for Atherosclerosis
Rankouhi, Tanja Rouhani, Keulen, Daniëlle van, Tempel, Dennie, Venhorst, Jennifer
Published in Current drug targets (01.01.2022)
Published in Current drug targets (01.01.2022)
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Journal Article
Homology Modeling of Rat and Human Cytochrome P450 2D (CYP2D) Isoforms and Computational Rationalization of Experimental Ligand-Binding Specificities
Venhorst, Jennifer, ter Laak, Antonius M, Commandeur, Jan N. M, Funae, Yoshihiko, Hiroi, Toyoko, Vermeulen, Nico P. E
Published in Journal of medicinal chemistry (02.01.2003)
Published in Journal of medicinal chemistry (02.01.2003)
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Journal Article
Identification of Ligand-binding Site III on the Immunoglobulin-like Domain of the Granulocyte Colony-stimulating Factor Receptor
Layton, Judith E., Hall, Nathan E., Connell, Fiona, Venhorst, Jennifer, Treutlein, Herbert R.
Published in The Journal of biological chemistry (28.09.2001)
Published in The Journal of biological chemistry (28.09.2001)
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Journal Article
Design, Synthesis, and Characterization of 7-Methoxy-4-(aminomethyl)coumarin as a Novel and Selective Cytochrome P450 2D6 Substrate Suitable for High-Throughput Screening
Onderwater, Rob C. A, Venhorst, Jennifer, Commandeur, Jan N. M, Vermeulen, Nico P. E
Published in Chemical research in toxicology (01.07.1999)
Published in Chemical research in toxicology (01.07.1999)
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Journal Article
Influence of N-Substitution of 7-Methoxy-4-(aminomethyl)-coumarin on Cytochrome P450 Metabolism and Selectivity
VENHORST, Jennifer, ONDERWATER, Rob C. A, MEERMAN, John H. N, COMMANDEUR, Jan N. M, VERMEULEN, Nico P. E
Published in Drug metabolism and disposition (01.12.2000)
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Published in Drug metabolism and disposition (01.12.2000)
Journal Article
Assessment of Scaffold Hopping Efficiency by Use of Molecular Interaction Fingerprints
Venhorst, Jennifer, Núñez, Sara, Terpstra, Jan Willem, Kruse, Chris G
Published in Journal of medicinal chemistry (12.06.2008)
Published in Journal of medicinal chemistry (12.06.2008)
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Journal Article
Assessment of a Novel Scoring Method Based on Solvent Accessible Surface Area Descriptors
Núñez, Sara, Venhorst, Jennifer, Kruse, Chris G
Published in Journal of chemical information and modeling (26.04.2010)
Published in Journal of chemical information and modeling (26.04.2010)
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Journal Article
A holistic approach to the safety assessment of exploratory drug targets
Venhorst, Jennifer, Rankouhi, Tanja Rouhani, Verschuren, Lars, van Someren, Eugene P., Kuper, Frieke C., Wolterbeek, Andre P.M., van de Brug, Fred J., Folkertsma, Simon, Krul, Cyrille A.M.
Published in Journal of pharmacological and toxicological methods (01.09.2016)
Published in Journal of pharmacological and toxicological methods (01.09.2016)
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Journal Article
N′-(Arylsulfonyl)pyrazoline-1-carboxamidines as Novel, Neutral 5-Hydroxytryptamine 6 Receptor (5-HT6R) Antagonists with Unique Structural Features
van Loevezijn, Arnold, Venhorst, Jennifer, Iwema Bakker, Wouter I, de Korte, Cor G, de Looff, Wouter, Verhoog, Stefan, van Wees, Jan-Willem, van Hoeve, Martijn, van de Woestijne, Rob P, van der Neut, Martina A. W, Borst, Alice J. M, van Dongen, Maria J. P, de Bruin, Natasja M. W. J, Keizer, Hiskias G, Kruse, Chris G
Published in Journal of medicinal chemistry (27.10.2011)
Published in Journal of medicinal chemistry (27.10.2011)
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Journal Article
Optimization of N'-(arylsulfonyl)pyrazoline-1-carboxamidines by exploiting a novel interaction site in the 5-HT sub(6) antagonistic binding pocket
Loevezijn, Arnold van, Venhorst, Jennifer, Bakker, Wouter IIwema, Lange, Jos HM, Looff, Wouter de, Henzen, Remco, Vries, Jelle de, Woestijne, Rob Pvan de, Hartog, Arnold Pden, Verhoog, Stefan, van der Neut, Martina AW, Bruin, Natasja MWJde, Kruse, Chris G
Published in Bioorganic & medicinal chemistry letters (15.03.2016)
Published in Bioorganic & medicinal chemistry letters (15.03.2016)
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Journal Article
Optimization of N ′-(arylsulfonyl)pyrazoline-1-carboxamidines by exploiting a novel interaction site in the 5-HT 6 antagonistic binding pocket
van Loevezijn, Arnold, Venhorst, Jennifer, Iwema Bakker, Wouter I., Lange, Jos H.M., de Looff, Wouter, Henzen, Remco, de Vries, Jelle, van de Woestijne, Rob P., den Hartog, Arnold P., Verhoog, Stefan, van der Neut, Martina A.W., de Bruin, Natasja M.W.J., Kruse, Chris G.
Published in Bioorganic & medicinal chemistry letters (01.03.2016)
Published in Bioorganic & medicinal chemistry letters (01.03.2016)
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Journal Article
Optimization of N′-(arylsulfonyl)pyrazoline-1-carboxamidines by exploiting a novel interaction site in the 5-HT6 antagonistic binding pocket
van Loevezijn, Arnold, Venhorst, Jennifer, Iwema Bakker, Wouter I., Lange, Jos H.M., de Looff, Wouter, Henzen, Remco, de Vries, Jelle, van de Woestijne, Rob P., den Hartog, Arnold P., Verhoog, Stefan, van der Neut, Martina A.W., de Bruin, Natasja M.W.J., Kruse, Chris G.
Published in Bioorganic & medicinal chemistry letters (15.03.2016)
Published in Bioorganic & medicinal chemistry letters (15.03.2016)
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Journal Article
Design of a High Fragment Efficiency Library by Molecular Graph Theory
Venhorst, Jennifer, Núñez, Sara, Kruse, Chris G
Published in ACS medicinal chemistry letters (09.12.2010)
Published in ACS medicinal chemistry letters (09.12.2010)
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Journal Article
Biophysical and physicochemical methods differentiate highly ligand-efficient human D-amino acid oxidase inhibitors
Lange, Jos H.M., Venhorst, Jennifer, van Dongen, Maria J.P., Frankena, Jurjen, Bassissi, Firas, de Bruin, Natasja M.W.J., Besten, Cathaline den, de Beer, Stephanie B.A., Oostenbrink, Chris, Markova, Natalia, Kruse, Chris G.
Published in European journal of medicinal chemistry (01.10.2011)
Published in European journal of medicinal chemistry (01.10.2011)
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Journal Article
Evaluation of a novel high-throughput assay for cytochrome P450 2D6 using 7-methoxy-4-(aminomethyl)-coumarin
Venhorst, Jennifer, Onderwater, Rob C.A, Meerman, John H.N, Vermeulen, Nico P.E, Commandeur, Jan N.M
Published in European journal of pharmaceutical sciences (01.12.2000)
Published in European journal of pharmaceutical sciences (01.12.2000)
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Journal Article