HES6 knockdown in human hematopoietic precursor cells reduces their in vivo engraftment potential and their capacity to differentiate into erythroid cells, B cells, T cells and plasmacytoid dendritic cells
De Vos, Tamara, Oatman, Nicole, Boehme, Lena, Putteman, Tom, Velghe, Imke, Van Droogenbroeck, Yana, De Munter, Stijn, Cesnekova, Michaela, Van Nieuwerburgh, Filip, Vandekerckhove, Bart, Philippe, Jan, Taghon, Tom
Published in Haematologica (Roma) (04.04.2024)
Published in Haematologica (Roma) (04.04.2024)
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GATA3 induces human T-cell commitment by restraining Notch activity and repressing NK-cell fate
Van de Walle, Inge, Dolens, Anne-Catherine, Durinck, Kaat, De Mulder, Katrien, Van Loocke, Wouter, Damle, Sagar, Waegemans, Els, De Medts, Jelle, Velghe, Imke, De Smedt, Magda, Vandekerckhove, Bart, Kerre, Tessa, Plum, Jean, Leclercq, Georges, Rothenberg, Ellen V., Van Vlierberghe, Pieter, Speleman, Frank, Taghon, Tom
Published in Nature communications (06.04.2016)
Published in Nature communications (06.04.2016)
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In vitro human embryonic stem cell hematopoiesis mimics MYB-independent yolk sac hematopoiesis
Vanhee, Stijn, De Mulder, Katrien, Van Caeneghem, Yasmine, Verstichel, Greet, Van Roy, Nadine, Menten, Björn, Velghe, Imke, Philippé, Jan, De Bleser, Dominique, Lambrecht, Bart N, Taghon, Tom, Leclercq, Georges, Kerre, Tessa, Vandekerckhove, Bart
Published in Haematologica (Roma) (01.02.2015)
Published in Haematologica (Roma) (01.02.2015)
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Functionally Mature CD4 and CD8 TCRαβ Cells Are Generated in OP9-DL1 Cultures from Human CD34+ Hematopoietic Cells
Van Coppernolle, Stefanie, Verstichel, Greet, Timmermans, Frank, Velghe, Imke, Vermijlen, David, De Smedt, Magda, Leclercq, Georges, Plum, Jean, Taghon, Tom, Vandekerckhove, Bart, Kerre, Tessa
Published in The Journal of immunology (1950) (15.10.2009)
Published in The Journal of immunology (1950) (15.10.2009)
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RHAMM/HMMR (CD168) is not an ideal target antigen for immunotherapy of acute myeloid leukemia
SNAUWAERT, Sylvia, VANHEE, Stijn, LECIERCQ, Georges, THIELEMANS, Kris, KERRE, Tessa, VANDEKERCKHOVE, Bart, GOETGELUK, Glenn, VERSTICHEL, Greet, VAN CAENEGHEM, Yasmine, VELGHE, Imke, PHILIPPE, Jan, BERNEMAN, Zwi N, PLUM, Jean, TAGHON, Tom
Published in Haematologica (Roma) (01.10.2012)
Published in Haematologica (Roma) (01.10.2012)
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HES6knockdown in human hematopoietic precursor cells reduces their in vivo engraftment potential and their capacity to differentiate into erythroid cells, B cells, T cells and plasmacytoid dendritic cells
De Vos, Tamara, Oatman, Nicole, Boehme, Lena, Putteman, Tom, Velghe, Imke, Van Droogenbroeck, Yana, De Munter, Stijn, Cesnekova, Michaela, Van Nieuwerburgh, Filip, Vandekerckhove, Bart, Philippe, Jan, Taghon, Tom
Published in Haematologica (Roma) (01.11.2024)
Published in Haematologica (Roma) (01.11.2024)
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An unexpected role for IRF8 during human T cell development
Taghon, Tom N, Liang, Kai Ling, Lavaert, Marieke, Roels, Juliette, Strubbe, Steven, Lambrechts, Nina, De Vos, Tamara, Boehme, Lena, Van Hulle, Jolien, Oatman, Nicole, Putteman, Tom, Velghe, Imke
Published in The Journal of immunology (1950) (01.05.2022)
Published in The Journal of immunology (1950) (01.05.2022)
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Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF
Liang, Kai Ling, Roels, Juliette, Lavaert, Marieke, Putteman, Tom, Boehme, Lena, Tilleman, Laurentijn, Velghe, Imke, Pegoretti, Valentina, Van de Walle, Inge, Sontag, Stephanie, Vandewalle, Jolien, Vandekerckhove, Bart, Leclercq, Georges, Van Vlierberghe, Pieter, Libert, Claude, Van Nieuwerburgh, Filip, Fischer, Roman, Kontermann, Roland E., Pfizenmaier, Klaus, Doody, Gina, Zenke, Martin, Taghon, Tom
Published in Nature immunology (01.03.2023)
Published in Nature immunology (01.03.2023)
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Generation of T Cells from Human Embryonic Stem Cell-Derived Hematopoietic Zones
Timmermans, Frank, Velghe, Imke, Vanwalleghem, Lieve, De Smedt, Magda, Van Coppernolle, Stefanie, Taghon, Tom, Moore, Harry D, Leclercq, Georges, Langerak, Anton W, Kerre, Tessa, Plum, Jean, Vandekerckhove, Bart
Published in The Journal of immunology (1950) (01.06.2009)
Published in The Journal of immunology (1950) (01.06.2009)
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Distinct Notch1 and BCL11B requirements mediate human γδ/αβ T cell development
Dolens, Anne‐Catherine, Durinck, Kaat, Lavaert, Marieke, Van der Meulen, Joni, Velghe, Imke, De Medts, Jelle, Weening, Karin, Roels, Juliette, De Mulder, Katrien, Volders, Pieter‐Jan, De Preter, Katleen, Kerre, Tessa, Vandekerckhove, Bart, Leclercq, Georges, Vandesompele, Jo, Mestdagh, Pieter, Van Vlierberghe, Pieter, Speleman, Frank, Taghon, Tom
Published in EMBO reports (06.05.2020)
Published in EMBO reports (06.05.2020)
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In vitro human embryonic stem cell hematopoiesis mimics MYB independent yolk sac hematopoiesis
Vanhee, Stijn, De Mulder, Katrien, Van Caeneghem, Yasmine, Van Roy, Nadine, Menten, Björn, Velghe, Imke, Philippé, Jan, Taghon, Tom, Leclercq, Georges, Kerre, Tessa, Vandekerckhove, Bart
Published in Experimental hematology (01.08.2014)
Published in Experimental hematology (01.08.2014)
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In vitro generation of immune cells from pluripotent stem cells
Vandekerckhove, Bart, Vanhee, Stijn, Van Coppernolle, Stefanie, Snauwaert, Sylvia, Velghe, Imke, Taghon, Tom, Leclercq, Georges, Kerre, Tessa, Plum, Jean
Published in Frontiers in bioscience (01.01.2011)
Published in Frontiers in bioscience (01.01.2011)
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cMYB expression during human in vitro hematopoiesis
Vanhee, Stijn, Van Caeneghem, Yasmine, De Mulder, Katrien, Velghe, Imke, Taveirne, Sylvie, Van Roy, Nadine, Menten, Björn, Snauwaert, Sylvia, Verstichel, Greet, Dullaers, Melissa, Goetgeluk, Glenn, Leclercq, Georges, Taghon, Tom, Plum, Jean, Kerre, Tessa, Vandekerckhove, Bart
Published in Experimental hematology (01.08.2013)
Published in Experimental hematology (01.08.2013)
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CD4 and CD8 TCRαβ Cells Are selected On MHC Expressed On Thymocyte Precursors in OP9-DL1 Cultures
Van Coppernolle, Stefanie, Vandekerckhove, Bart, Verstichel, Greet, Velghe, Imke, Taghon, Tom, Leclercq, Georges, Plum, Jean, Kerre, Tessa C.C.
Published in Blood (20.11.2009)
Published in Blood (20.11.2009)
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OP9-DL1 Cell Line Supports the Development of Phenotypically and Functionally Mature Tcrαβ And Tcrγδ T Cells, through Both Conventional and Aberrant Developmental Pathways
Kerre, Tessa C.C., Verstichel, Greet, Van Coppernolle, Stefanie, Velghe, Imke, Timmermans, Frank, Plum, Jean, Vandekerckhove, Bart
Published in Blood (16.11.2008)
Published in Blood (16.11.2008)
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Generation of T Cells from Human Embryonic Stem Cells
Timmermans, Frank, Velghe, Imke, Van Walleghem, Lieve, De Smedt, Magda, Van Coppernolle, Stefanie, Leclercq, Georges, Taghon, Tom, Moore, Harry, Langerak, Anton W, Kerre, Tessa C.C., Plum, Jean, Vandekerckhove, Bart
Published in Blood (16.11.2008)
Published in Blood (16.11.2008)
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Functionally mature CD4 and CD8 TCRalphabeta cells are generated in OP9-DL1 cultures from human CD34+ hematopoietic cells
Van Coppernolle, Stefanie, Verstichel, Greet, Timmermans, Frank, Velghe, Imke, Vermijlen, David, De Smedt, Magda, Leclercq, Georges, Plum, Jean, Taghon, Tom, Vandekerckhove, Bart, Kerre, Tessa
Published in The Journal of immunology (1950) (15.10.2009)
Published in The Journal of immunology (1950) (15.10.2009)
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Journal Article
Functionally Mature CD4 and CD8 TCR{alpha}{beta} Cells Are Generated in OP9-DL1 Cultures from Human CD34+ Hematopoietic Cells
Van Coppernolle, Stefanie, Verstichel, Greet, Timmermans, Frank, Velghe, Imke, Vermijlen, David, De Smedt, Magda, Leclercq, Georges, Plum, Jean, Taghon, Tom, Vandekerckhove, Bart, Kerre, Tessa
Published in The Journal of immunology (1950) (15.10.2009)
Published in The Journal of immunology (1950) (15.10.2009)
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