Elezanumab, a clinical stage human monoclonal antibody that selectively targets repulsive guidance molecule A to promote neuroregeneration and neuroprotection in neuronal injury and demyelination models
Huang, Lili, Fung, Emma, Bose, Sahana, Popp, Andreas, Böser, Preethne, Memmott, John, Kutskova, Yuliya A., Miller, Renee, Tarcsa, Edit, Klein, Corinna, Veldman, Geertruida M., Mueller, Bernhard K., Cui, Yi-Fang
Published in Neurobiology of disease (01.11.2021)
Published in Neurobiology of disease (01.11.2021)
Get full text
Journal Article
Targeting Repulsive Guidance Molecule A to Promote Regeneration and Neuroprotection in Multiple Sclerosis
Demicheva, Elena, Cui, Yi-Fang, Bardwell, Philip, Barghorn, Stefan, Kron, Martina, Meyer, Axel H., Schmidt, Martin, Gerlach, Björn, Leddy, Mary, Barlow, Eve, O’Connor, Elizabeth, Choi, Chee-Ho, Huang, Lili, Veldman, Geertruida M., Rus, Horea, Shabanzadeh, Alireza P., Tassew, Nardos G., Monnier, Philippe P., Müller, Thomas, Calabresi, Peter A., Schoemaker, Hans, Mueller, Bernhard K.
Published in Cell reports (Cambridge) (24.03.2015)
Published in Cell reports (Cambridge) (24.03.2015)
Get full text
Journal Article
A Quantitative Systems Pharmacology Consortium Approach to Managing Immunogenicity of Therapeutic Proteins
Kierzek, Andrzej M., Hickling, Timothy P., Figueroa, Isabel, Kalvass, J. Cory, Nijsen, Marjoleen, Mohan, Krithika, Veldman, Geertruida M., Yamada, Akihiro, Sayama, Hiroyuki, Yokoo, Sachiko, Gulati, Abhishek, Dhanikula, Renu S., Gokemeijer, Jochem, Leil, Tarek A., Thalhauser, Craig J., Giorgi, Mario, Swat, Maciej J., Chelliah, Vijayalakshmi, Small, Ben G., Benson, Neil, Walker, Michael, Gadkar, Kapil, Quarmby, Valerie, Deng, Rong, Ferrante, Andrea, Dickinson, Gemma L., Van Der Walt, Jan‐Stefan, Zhou, Lian, Chen, Xiaoying, Jones, Hannah M., Narula, Jatin, Tourdot, Sophie, Lavé, Thierry, Ribba, Benjamin, Graaf, Piet H.
Published in CPT: pharmacometrics and systems pharmacology (01.11.2019)
Published in CPT: pharmacometrics and systems pharmacology (01.11.2019)
Get full text
Journal Article
Inhibition of myostatin in adult mice increases skeletal muscle mass and strength
Whittemore, Lisa-Anne, Song, Kening, Li, Xiangping, Aghajanian, Jane, Davies, Monique, Girgenrath, Stefan, Hill, Jennifer J., Jalenak, Mary, Kelley, Pamela, Knight, Andrea, Maylor, Rich, O’Hara, Denise, Pearson, Adele, Quazi, Amira, Ryerson, Stephanie, Tan, Xiang-Yang, Tomkinson, Kathleen N., Veldman, Geertruida M., Widom, Angela, Wright, Jill F., Wudyka, Steve, Zhao, Liz, Wolfman, Neil M.
Published in Biochemical and biophysical research communications (24.01.2003)
Published in Biochemical and biophysical research communications (24.01.2003)
Get full text
Journal Article
Anti–Interleukin-12 Antibody for Active Crohn's Disease
Mannon, Peter J, Fuss, Ivan J, Mayer, Lloyd, Elson, Charles O, Sandborn, William J, Present, Daniel, Dolin, Ben, Goodman, Nancy, Groden, Catherine, Hornung, Ronald L, Quezado, Martha, Neurath, Markus F, Salfeld, Jochen, Veldman, Geertruida M, Schwertschlag, Ullrich, Strober, Warren
Published in The New England journal of medicine (11.11.2004)
Published in The New England journal of medicine (11.11.2004)
Get full text
Journal Article
Syncytin is a captive retroviral envelope protein involved in human placental morphogenesis
McCoy, John M, Mi, Sha, Lee, Xinhua, Li, Xiang-ping, Veldman, Geertruida M, Finnerty, Heather, Racie, Lisa, LaVallie, Edward, Tang, Xiang-Yang, Edouard, Philippe, Howes, Steve, Keith, James C
Published in Nature (London) (17.02.2000)
Published in Nature (London) (17.02.2000)
Get full text
Journal Article
Crystal structure reveals conservation of amyloid-β conformation recognized by 3D6 following humanization to bapineuzumab
Feinberg, Hadar, Saldanha, José W, Diep, Linnea, Goel, Amita, Widom, Angela, Veldman, Geertruida M, Weis, William I, Schenk, Dale, Basi, Guriqbal S
Published in Alzheimer's research & therapy (02.06.2014)
Published in Alzheimer's research & therapy (02.06.2014)
Get full text
Journal Article
Expression cloning of a functional glycoprotein ligand for P-selectin
Sako, Dianne, Chang, Xiao-Jia, Barone, Karen M., Vachino, Gloria, White, Holly M., Shaw, Gray, Veldman, Geertruida M., Bean, Kevin M., Ahern, Tim J., Furie, Bruce, Cumming, Dale A., Larsen, Glenn R.
Published in Cell (17.12.1993)
Published in Cell (17.12.1993)
Get full text
Journal Article
Temporal associations between interleukin 22 and the extracellular domains of IL-22R and IL-10R2
Li, Jing, Tomkinson, Kathy N, Tan, Xiang-Yang, Wu, Paul, Yan, Grace, Spaulding, Vikki, Deng, Bijia, Annis-Freeman, Bethany, Heveron, Kathleen, Zollner, Richard, De Zutter, Gerard, Wright, Jill F, Crawford, Tara K, Liu, Wei, Jacobs, Kenneth A, Wolfman, Neil M, Ling, Vincent, Pittman, Debra D, Veldman, Geertruida M, Fouser, Lynette A
Published in International immunopharmacology (01.05.2004)
Published in International immunopharmacology (01.05.2004)
Get full text
Journal Article
P-selectin Glycoprotein Ligand-1 Is the Major Counter-receptor for P-selectin on Stimulated T Cells and Is Widely Distributed in Non-functional Form on Many Lymphocytic Cells
Vachino, Gloria, Veldman, Geertruida M., Kumar, Ravindra, Sako, Dianne, Fouser, Lynette A., Cumming, Dale A., Berndt, Michael C., Chang, Xiao-Jia
Published in The Journal of biological chemistry (15.09.1995)
Published in The Journal of biological chemistry (15.09.1995)
Get full text
Journal Article
A Novel Cobra Venom Metalloproteinase, Mocarhagin, Cleaves a 10-Amino Acid Peptide from the Mature N Terminus of P-selectin Glycoprotein Ligand Receptor, PSGL-1, and Abolishes P-selectin Binding ()
De Luca, Mariagrazia, Dunlop, Lindsay C., Andrews, Robert K., Flannery, John V., Ettling, Rebecca, Cumming, Dale A., Veldman, Geertruida M., Berndt, Michael C.
Published in The Journal of biological chemistry (10.11.1995)
Published in The Journal of biological chemistry (10.11.1995)
Get full text
Journal Article
ANTIBODIES AGAINST HUMAN IL-22 AND USES THEREFOR
LOWE DAVID C, COHEN SUZANNE E, VALGE ARCHER VIIA, VELDMAN GEERTRUIDA M, RUSSELL CAROLINE S, THOM ALBERT B, LI JING, GILL DAVINDER S, FOUSER LYNETTE A, MINTER RALPH R
Year of Publication 14.08.2014
Get full text
Year of Publication 14.08.2014
Patent
ANTIBODIES AGAINST HUMAN INTERLEUKIN-13 AND USES THEREFOR
GOLDMAN SAMUEL J, VELDMAN GEERTRUIDA M, DONALDSON DEBRA D, MARQUETTE KIMBERLY ANN, FEYFANT ERIC, KASAIAN MARION T, LIN LAURA LONG, TCHISTIAKOVA LIOUDMILA, TAN XIANG-YANG, WOOD NANCY L, TAM AMY SZEPUI, WIDOM ANGELA M, SHANE TANIA, PARRIS KEVIN D, FITZ LORI J
Year of Publication 26.02.2015
Get full text
Year of Publication 26.02.2015
Patent
Genomic Organization and Chromosomal Localization of the Gene Encoding Human P-selectin Glycoprotein Ligand
Veldman, Geertruida M., Bean, Kevin M., Cumming, Dale A., Eddy, Roger L., Sait, Sheila N.J., Shows, Thomas B.
Published in The Journal of biological chemistry (07.07.1995)
Published in The Journal of biological chemistry (07.07.1995)
Get full text
Journal Article
NEUTRALIZING ANTIBODIES AGAINST GDF-8 AND USES THEREFOR
VALGE ARCHER VIIA, VELDMAN GEERTRUIDA M, DAVIES MONIQUE V, RUSSELL CAROLINE, GROVE BRIDGES KRISTIE, FIELD ANNE, SONG KENING, WOLFMAN NEIL M
Year of Publication 23.04.2012
Get full text
Year of Publication 23.04.2012
Patent
HUMAN ANTIBODIES THAT BIND HUMAN IL-12 AND METHODS FOR PRODUCING
VENTURINI AMY, TRACEY DANIEL E, KAYMAKCALAN ZEHRA, VELDMAN GEERTRUIDA M, WIDOM ANGELA, DUNCAN ALEXANDER R, WHITE MICHAEL, SMITH STEPHEN, SAKORAFAS PAUL, DU FOU SARAH L, SALFELD JOCHEN G, MYLES ANGELA, FRIEDRICH STUART, ROGUSKA MICHAEL, ELVIN JOHN G, PASKIND MICHAEL, LABKOVSKY BORIS, DERBYSHIRE ELAINE J, BANERJEE SUBHASHIS, WARNE NICHOLAS W, CARMEN SARA, HOLTET THOR LAS
Year of Publication 30.07.2014
Get full text
Year of Publication 30.07.2014
Patent
HUMAN ANTIBODIES THAT BIND HUMAN IL-12 AND METHODS FOR PRODUCING
VENTURINI AMY, TRACEY DANIEL E, KAYMAKCALAN ZEHRA, VELDMAN GEERTRUIDA M, WIDOM ANGELA, DUNCAN ALEXANDER R, WHITE MICHAEL, SMITH STEPHEN, SAKORAFAS PAUL, DU FOU SARAH L, SALFELD JOCHEN G, MYLES ANGELA, FRIEDRICH STUART, ROGUSKA MICHAEL, ELVIN JOHN G, PASKIND MICHAEL, LABKOVSKY BORIS, DERBYSHIRE ELAINE J, BANERJEE SUBHASHIS, WARNE NICHOLAS W, CARMEN SARA, HOLTET THOR LAS
Year of Publication 25.09.2013
Get full text
Year of Publication 25.09.2013
Patent
ANTIBODIES AGAINST HUMAN INTERLEUKIN-13 AND USES THEREFOR
GOLDMAN SAMUEL J, VELDMAN GEERTRUIDA M, DONALDSON DEBRA D, MARQUETTE KIMBERLY ANN, FEYFANT ERIC, KASAIAN MARION T, LIN LAURA LONG, TCHISTIAKOVA LIOUDMILA, WOOD NANCY L, TAM AMY SZEPUI, WIDOM ANGELA M, SHANE TANIA, TAN XIANG YANG, PARRIS KEVIN D, FITZ LORI J
Year of Publication 24.09.2013
Get full text
Year of Publication 24.09.2013
Patent