Mucus Enhances Gut Homeostasis and Oral Tolerance by Delivering Immunoregulatory Signals
Shan, Meimei, Gentile, Maurizio, Yeiser, John R., Walland, A. Cooper, Bornstein, Victor U., Chen, Kang, He, Bing, Cassis, Linda, Bigas, Anna, Cois, Montserrat, Comerma, Laura, Huang, Bihui, Blander, Magarian, Xiong, Huabao, Mayer, Lloyd, Berin, Cecilia, Augenlicht, Leonard H., Velcich, Anna, Cerutti, Andrea
Published in Science (American Association for the Advancement of Science) (25.10.2013)
Published in Science (American Association for the Advancement of Science) (25.10.2013)
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Journal Article
The Mucin Muc2 Limits Pathogen Burdens and Epithelial Barrier Dysfunction during Salmonella enterica Serovar Typhimurium Colitis
Zarepour, Maryam, Bhullar, Kirandeep, Montero, Marinieve, Ma, Caixia, Huang, Tina, Velcich, Anna, Xia, Lijun, Vallance, Bruce A
Published in Infection and Immunity (01.10.2013)
Published in Infection and Immunity (01.10.2013)
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Journal Article
Muc2 protects against lethal infectious colitis by disassociating pathogenic and commensal bacteria from the colonic mucosa
Bergstrom, Kirk S B, Kissoon-Singh, Vanessa, Gibson, Deanna L, Ma, Caixia, Montero, Marinieve, Sham, Ho Pan, Ryz, Natasha, Huang, Tina, Velcich, Anna, Finlay, B Brett, Chadee, Kris, Vallance, Bruce A
Published in PLoS pathogens (01.05.2010)
Published in PLoS pathogens (01.05.2010)
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Journal Article
MUC2 mucin deficiency alters inflammatory and metabolic pathways in the mouse intestinal mucosa
Tadesse, Selamawit, Corner, Georgia, Dhima, Elena, Houston, Michele, Guha, Chandan, Augenlicht, Leonard, Velcich, Anna
Published in Oncotarget (22.09.2017)
Published in Oncotarget (22.09.2017)
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Journal Article
Histone Deacetylase 3 (HDAC3) and Other Class I HDACs Regulate Colon Cell Maturation and p21 Expression and Are Deregulated in Human Colon Cancer
Wilson, Andrew J., Byun, Do-Sun, Popova, Natalia, Murray, Lucas B., L'Italien, Kaitlin, Sowa, Yoshihiro, Arango, Diego, Velcich, Anna, Augenlicht, Leonard H., Mariadason, John M.
Published in The Journal of biological chemistry (12.05.2006)
Published in The Journal of biological chemistry (12.05.2006)
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Journal Article
Mucin gene deficiency in mice impairs host resistance to an enteric parasitic infection
Hasnain, Sumaira Z, Wang, Huaqing, Ghia, Jean-Eric, Haq, Nihal, Deng, Yikang, Velcich, Anna, Grencis, Richard K, Thornton, David J, Khan, Waliul I
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2010)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2010)
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Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation
Tang, Alan T, Sullivan, Katie R, Hong, Courtney C, Goddard, Lauren M, Mahadevan, Aparna, Ren, Aileen, Pardo, Heidy, Peiper, Amy, Griffin, Erin, Tanes, Ceylan, Mattei, Lisa M, Yang, Jisheng, Li, Li, Mericko-Ishizuka, Patricia, Shen, Le, Hobson, Nicholas, Girard, Romuald, Lightle, Rhonda, Moore, Thomas, Shenkar, Robert, Polster, Sean P, Rödel, Claudia J, Li, Ning, Zhu, Qin, Whitehead, Kevin J, Zheng, Xiangjian, Akers, Amy, Morrison, Leslie, Kim, Helen, Bittinger, Kyle, Lengner, Christopher J, Schwaninger, Markus, Velcich, Anna, Augenlicht, Leonard, Abdelilah-Seyfried, Salim, Min, Wang, Marchuk, Douglas A, Awad, Issam A, Kahn, Mark L
Published in Science translational medicine (27.11.2019)
Published in Science translational medicine (27.11.2019)
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Journal Article
Spontaneous colitis in Muc2-deficient mice reflects clinical and cellular features of active ulcerative colitis
Wenzel, Ulf A, Magnusson, Maria K, Rydström, Anna, Jonstrand, Caroline, Hengst, Julia, Johansson, Malin E V, Velcich, Anna, Öhman, Lena, Strid, Hans, Sjövall, Henrik, Hansson, Gunnar C, Wick, Mary Jo
Published in PloS one (19.06.2014)
Published in PloS one (19.06.2014)
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Journal Article
Colorectal Cancer in Mice Genetically Deficient in the Mucin Muc2
Velcich, Anna, Yang, WanCai, Heyer, Joerg, Fragale, Alessandra, Nicholas, Courtney, Viani, Stephanie, Kucherlapati, Raju, Lipkin, Martin, Yang, Kan, Augenlicht, Leonard
Published in Science (American Association for the Advancement of Science) (01.03.2002)
Published in Science (American Association for the Advancement of Science) (01.03.2002)
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Journal Article
Natural anti-intestinal goblet cell autoantibody production from marginal zone B cells
Ichikawa, Daiju, Asano, Masanao, Shinton, Susan A, Brill-Dashoff, Joni, Formica, Anthony M, Velcich, Anna, Hardy, Richard R, Hayakawa, Kyoko
Published in The Journal of immunology (1950) (15.01.2015)
Published in The Journal of immunology (1950) (15.01.2015)
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Journal Article
Dietary Induction of Colonic Tumors in a Mouse Model of Sporadic Colon Cancer
KAN YANG, KURIHARA, Naoto, VELCICH, Anna, LIPKIN, Martin, AUGENLICHT, Leonard, KUNHUA FAN, NEWMARK, Harold, RIGAS, Basil, BANCROFT, Laura, CORNER, Georgia, LIVOTE, Elayne, LESSER, Martin, EDELMANN, Winfried
Published in Cancer research (Chicago, Ill.) (01.10.2008)
Published in Cancer research (Chicago, Ill.) (01.10.2008)
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Journal Article
Interaction of Muc2 and Apc on Wnt Signaling and in Intestinal Tumorigenesis : Potential Role of Chronic Inflammation
KAN YANG, POPOVA, Natalia V, EDELMANN, Winfried, LIPKIN, Martin, AUGENLICHT, Leonard, VELCICH, Anna, WAN CAI YANG, LOZONSCHI, Ioanna, TADESSE, Selam, KENT, Scott, BANCROFT, Laura, MATISE, Ilze, CORMIER, Robert T, SCHERER, Stefan J
Published in Cancer research (Chicago, Ill.) (15.09.2008)
Published in Cancer research (Chicago, Ill.) (15.09.2008)
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Journal Article
A Model for Precise and Uniform Pelvic- and Limb-Sparing Abdominal Irradiation to Study the Radiation-Induced Gastrointestinal Syndrome in Mice Using Small Animal Irradiation Systems
Brodin, N. Patrik, Velcich, Anna, Guha, Chandan, Tomé, Wolfgang A.
Published in Dose-response (01.03.2017)
Published in Dose-response (01.03.2017)
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Journal Article
Inactivation of p21 Enhances Intestinal Tumor Formation in Muc2−/− Mice
Yang, WanCai, Velcich, Anna, Lozonschi, Ioana, Liang, Jiao, Nicholas, Courtney, Zhuang, Min, Bancroft, Laura, Augenlicht, Leonard H.
Published in The American journal of pathology (01.04.2005)
Published in The American journal of pathology (01.04.2005)
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Journal Article
Methotrexate-induced mucositis in mucin 2-deficient mice
de Koning, Barbara A.E., Sluis, Maria van der, Lindenbergh-Kortleve, Dicky J., Velcich, Anna, Pieters, Rob, Büller, Hans A., Einerhand, Alexandra W.C., Renes, Ingrid B.
Published in Journal of cellular physiology (01.01.2007)
Published in Journal of cellular physiology (01.01.2007)
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Journal Article
Organization and Regulatory Aspects of the Human Intestinal Mucin Gene (MUC2) Locus
Velcich, Anna, Palumbo, Lisa, Selleri, Licia, Evans, Glen, Augenlicht, Leonard
Published in The Journal of biological chemistry (21.03.1997)
Published in The Journal of biological chemistry (21.03.1997)
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Journal Article
Importance and regulation of the colonic mucus barrier in a mouse model of colitis
Petersson, J, Schreiber, O, Hansson, G C, Gendler, S J, Velcich, A, Lundberg, J O, Roos, S, Holm, L, Phillipson, M
Published in American journal of physiology: Gastrointestinal and liver physiology (01.02.2011)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.02.2011)
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Journal Article
Muc2-deficient mice spontaneously develop colitis, indicating that MUC2 is critical for colonic protection
Van der Sluis, Maria, De Koning, Barbara A E, De Bruijn, Adrianus C J M, Velcich, Anna, Meijerink, Jules P P, Van Goudoever, Johannes B, Büller, Hans A, Dekker, Jan, Van Seuningen, Isabelle, Renes, Ingrid B, Einerhand, Alexandra W C
Published in Gastroenterology (New York, N.Y. 1943) (01.07.2006)
Published in Gastroenterology (New York, N.Y. 1943) (01.07.2006)
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