Rational Design of Macrocyclic Noncovalent Inhibitors of SARS-CoV-2 M pro from a DNA-Encoded Chemical Library Screening Hit That Demonstrate Potent Inhibition against Pan-Coronavirus Homologues and Nirmatrelvir-Resistant Variants
Wang, Xu, Gotchev, Dimitar, Fan, Kristi Yi, Vega, Marvin M, Mani, Nagraj, McGovern-Gooch, Kayleigh, Cuconati, Andrea, Tercero, Breanna, Wang, Xiaohe, Carpino, Philip, Maskos, Klaus, Centrella, Paolo A, Schmitt, Andreas, Preuss, Franziska, Prasad, Archna, Chen, Chia-Yi, Clark, Matthew A, Guilinger, John P, Johnstone, Shawn, von König, Konstanze, Keefe, Anthony D, Liu, Jenny, Turcotte, Stéphane, Zhang, Ying, Konz Makino, Debora L, Lam, Angela M, Cole, Andrew G, Sofia, Michael J
Published in Journal of medicinal chemistry (25.10.2024)
Published in Journal of medicinal chemistry (25.10.2024)
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Journal Article
Ion Mobility Mass Spectrometry as an Efficient Tool for Identification of Streptorubin B in Streptomyces coelicolor M145
Marshall, Andrew P, Johnson, Andrew R, Vega, Marvin M, Thomson, Regan J, Carlson, Erin E
Published in Journal of natural products (Washington, D.C.) (24.01.2020)
Published in Journal of natural products (Washington, D.C.) (24.01.2020)
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Journal Article
Genome Mining and Metabolomics Uncover a Rare d‑Capreomycidine Containing Natural Product and Its Biosynthetic Gene Cluster
Tryon, James H, Rote, Jennifer C, Chen, Li, Robey, Matthew T, Vega, Marvin M, Phua, Wan Cheng, Metcalf, William W, Ju, Kou-San, Kelleher, Neil L, Thomson, Regan J
Published in ACS chemical biology (20.11.2020)
Published in ACS chemical biology (20.11.2020)
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Journal Article
Synthesis and surface spectroscopy of α-pinene isotopologues and their corresponding secondary organic material
Upshur, Mary Alice, Vega, Marvin M, Bé, Ariana Gray, Chase, Hilary M, Zhang, Yue, Tuladhar, Aashish, Chase, Zizwe A, Fu, Li, Ebben, Carlena J, Wang, Zheming, Martin, Scot T, Geiger, Franz M, Thomson, Regan J
Published in Chemical science (Cambridge) (28.09.2019)
Published in Chemical science (Cambridge) (28.09.2019)
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Journal Article
Enantioselective synthesis of metacycloprodigiosin via the ‘Wasserman pyrrole’
Vega, Marvin M., Crain, Diana M., Konkol, Leah C., Thomson, Regan J.
Published in Tetrahedron letters (03.06.2015)
Published in Tetrahedron letters (03.06.2015)
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Journal Article
Structure–Activity Relationship-based Optimization of Small Temporin-SHf Analogs with Potent Antibacterial Activity
André, Sonia, Washington, Shannon K, Darby, Emily, Vega, Marvin M, Filip, Ari D, Ash, Nathaniel S, Muzikar, Katy A, Piesse, Christophe, Foulon, Thierry, O’Leary, Daniel J, Ladram, Ali
Published in ACS chemical biology (16.10.2015)
Published in ACS chemical biology (16.10.2015)
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Journal Article
Rational Design of Macrocyclic Noncovalent Inhibitors of SARS-CoV-2 Mpro from a DNA-Encoded Chemical Library Screening Hit That Demonstrate Potent Inhibition against Pan-Coronavirus Homologues and Nirmatrelvir-Resistant Variants
Wang, Xu, Gotchev, Dimitar, Fan, Kristi Yi, Vega, Marvin M, Mani, Nagraj, McGovern-Gooch, Kayleigh, Cuconati, Andrea, Tercero, Breanna, Wang, Xiaohe, Carpino, Philip, Maskos, Klaus, Centrella, Paolo A, Schmitt, Andreas, Preuss, Franziska, Prasad, Archna, Chen, Chia-Yi, Clark, Matthew A, Guilinger, John P, Johnstone, Shawn, von König, Konstanze, Keefe, Anthony D, Liu, Jenny, Turcotte, Stéphane, Zhang, Ying, Konz Makino, Debora L, Lam, Angela M, Cole, Andrew G, Sofia, Michael J
Published in Journal of medicinal chemistry (25.10.2024)
Published in Journal of medicinal chemistry (25.10.2024)
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Journal Article
Synthesis Enabled Investigations into the Acidity and Stability of Atmospherically-Relevant Isoprene-Derived Organosulfates
Varelas, Jonathan G., Vega, Marvin M., Upshur, Mary Alice, Geiger, Franz M., Thomson, Regan J.
Published in ACS earth and space chemistry (15.12.2022)
Published in ACS earth and space chemistry (15.12.2022)
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Journal Article
Synthesis and surface spectroscopy of α-pinene isotopologues and their corresponding secondary organic material† †Electronic supplementary information (ESI) available: Detailed information for the synthesis of isotopologues, SOM collection, and supplementary SFG data. See DOI: 10.1039/c9sc02399b
Upshur, Mary Alice, Vega, Marvin M., Bé, Ariana Gray, Chase, Hilary M., Zhang, Yue, Tuladhar, Aashish, Chase, Zizwe A., Fu, Li, Ebben, Carlena J., Wang, Zheming, Martin, Scot T., Geiger, Franz M., Thomson, Regan J.
Published in Chemical science (Cambridge) (31.07.2019)
Published in Chemical science (Cambridge) (31.07.2019)
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Journal Article
MAIN PROTEASE (M PRO) INHIBITORS AND METHODS USING SAME
COLE, Andrew G, KULTGEN, Steven G, DORSEY, Bruce D, SOFIA, Michael J, VEGA, Marvin M, GOTCHEV, Dimitar B, LINDSTROM, Aaron R, NGUYEN, Duyan, FAN, Yi, WANG, Xu, CHEN, Shuai
Year of Publication 06.04.2023
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Year of Publication 06.04.2023
Patent
Main protease (Mpro) inhibitors and methods using same
VEGA, MARVIN M, COLE, ANDREW G, KULTGEN, STEVEN G, WANG, XU, DORSEY, BRUCE D, FAN, YI, CHEN, SHUAI, NGUYEN, DUYAN, GOTCHEV, DIMITAR B, LINDSTROM, AARON R, SOFIA, MICHAEL J
Year of Publication 01.08.2023
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Year of Publication 01.08.2023
Patent