Mechanisms by which adiponectin reverses high fat diet-induced insulin resistance in mice
Li, Xiruo, Zhang, Dongyan, Vatner, Daniel F., Goedeke, Leigh, Hirabara, Sandro M., Zhang, Ye, Perry, Rachel J., Shulman, Gerald I.
Published in Proceedings of the National Academy of Sciences - PNAS (22.12.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (22.12.2020)
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Acetyl‐CoA Carboxylase Inhibition Reverses NAFLD and Hepatic Insulin Resistance but Promotes Hypertriglyceridemia in Rodents
Goedeke, Leigh, Bates, Jamie, Vatner, Daniel F., Perry, Rachel J., Wang, Ting, Ramirez, Ricardo, Li, Li, Ellis, Matthew W., Zhang, Dongyan, Wong, Kari E., Beysen, Carine, Cline, Gary W., Ray, Adrian S., Shulman, Gerald I.
Published in Hepatology (Baltimore, Md.) (01.12.2018)
Published in Hepatology (Baltimore, Md.) (01.12.2018)
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Insulin-independent regulation of hepatic triglyceride synthesis by fatty acids
Vatner, Daniel F., Majumdar, Sachin K., Kumashiro, Naoki, Petersen, Max C., Rahimi, Yasmeen, Gattu, Arijeet K., Bears, Mitchell, Camporez, João-Paulo G., Cline, Gary W., Jurczak, Michael J., Samuel, Varman T., Shulman, Gerald I.
Published in Proceedings of the National Academy of Sciences - PNAS (27.01.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (27.01.2015)
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Journal Article
Metabolic control analysis of hepatic glycogen synthesis in vivo
Nozaki, Yuichi, Petersen, Max C., Zhang, Dongyan, Vatner, Daniel F., Perry, Rachel J., Abulizi, Abudukadier, Haedersdal, Sofie, Zhang, Xian-Man, Butrico, Gina M., Samuel, Varman T., Mason, Graeme F., Cline, Gary W., Petersen, Kitt F., Rothman, Douglas L., Shulman, Gerald I.
Published in Proceedings of the National Academy of Sciences - PNAS (07.04.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (07.04.2020)
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Journal Article
Hepatic Diacylglycerol-Associated Protein Kinase Cε Translocation Links Hepatic Steatosis to Hepatic Insulin Resistance in Humans
ter Horst, Kasper W., Gilijamse, Pim W., Versteeg, Ruth I., Ackermans, Mariette T., Nederveen, Aart J., la Fleur, Susanne E., Romijn, Johannes A., Nieuwdorp, Max, Zhang, Dongyan, Samuel, Varman T., Vatner, Daniel F., Petersen, Kitt F., Shulman, Gerald I., Serlie, Mireille J.
Published in Cell reports (Cambridge) (06.06.2017)
Published in Cell reports (Cambridge) (06.06.2017)
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Membrane-bound sn-1,2-diacylglycerols explain the dissociation of hepatic insulin resistance from hepatic steatosis in MTTP knockout mice
Abulizi, Abudukadier, Vatner, Daniel F., Ye, Zhang, Wang, Yongliang, Camporez, Joao-Paulo, Zhang, Dongyan, Kahn, Mario, Lyu, Kun, Sirwi, Alaa, Cline, Gary W., Hussain, M. Mahmood, Aspichueta, Patricia, Samuel, Varman T., Shulman, Gerald I.
Published in Journal of lipid research (01.12.2020)
Published in Journal of lipid research (01.12.2020)
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Targeting Pyruvate Carboxylase Reduces Gluconeogenesis and Adiposity and Improves Insulin Resistance
KUMASHIRO, Naoki, BEDDOW, Sara A, KAHN, Mario, PERLER, Bryce K, PUCHOWICZ, Michelle A, VARA PRASAD MANCHEM, BHANOT, Sanjay, STILL, Christopher D, GERHARD, Glenn S, PETERSEN, Kitt Falk, CLINE, Gary W, SHULMAN, Gerald I, VATNER, Daniel F, SAMUEL, Varman T, MAJUMDAR, Sachin K, CANTLEY, Jennifer L, GUEBRE-EGZIABHER, Fitsum, FAT, Ioana, GUIGNI, Blas, JURCZAK, Michael J, BIRKENFELD, Andreas L
Published in Diabetes (New York, N.Y.) (01.07.2013)
Published in Diabetes (New York, N.Y.) (01.07.2013)
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Absence of ANGPTL4 in adipose tissue improves glucose tolerance and attenuates atherogenesis
Aryal, Binod, Singh, Abhishek K, Zhang, Xinbo, Varela, Luis, Rotllan, Noemi, Goedeke, Leigh, Chaube, Balkrishna, Camporez, Joao-Paulo, Vatner, Daniel F, Horvath, Tamas L, Shulman, Gerald I, Suárez, Yajaira, Fernández-Hernando, Carlos
Published in JCI insight (22.03.2018)
Published in JCI insight (22.03.2018)
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Journal Article
Role of patatin‐like phospholipase domain‐containing 3 on lipid‐induced hepatic steatosis and insulin resistance in rats
Kumashiro, Naoki, Yoshimura, Toru, Cantley, Jennifer L., Majumdar, Sachin K., Guebre‐Egziabher, Fitsum, Kursawe, Romy, Vatner, Daniel F., Fat, Ioana, Kahn, Mario, Erion, Derek M., Zhang, Xian‐Man, Zhang, Dongyan, Manchem, Vara Prasad, Bhanot, Sanjay, Gerhard, Glenn S., Petersen, Kitt F., Cline, Gary W., Samuel, Varman T., Shulman, Gerald I.
Published in Hepatology (Baltimore, Md.) (01.05.2013)
Published in Hepatology (Baltimore, Md.) (01.05.2013)
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Insulin increases placental triglyceride as a potential mechanism for fetal adiposity in maternal obesity
Anam, Anika K., Cooke, Katherine M., Dratver, Milana Bochkur, O'Bryan, Jane V., Perley, Lauren E., Guller, Seth M., Hwang, Janice J., Taylor, Hugh S., Goedeke, Leigh, Kliman, Harvey J., Vatner, Daniel F., Flannery, Clare A.
Published in Molecular metabolism (Germany) (01.10.2022)
Published in Molecular metabolism (Germany) (01.10.2022)
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Journal Article
Deletion of the diabetes candidate gene Slc16a13 in mice attenuates diet-induced ectopic lipid accumulation and insulin resistance
Schumann, Tina, König, Jörg, von Loeffelholz, Christian, Vatner, Daniel F, Zhang, Dongyan, Perry, Rachel J, Bernier, Michel, Chami, Jason, Henke, Christine, Kurzbach, Anica, El-Agroudy, Nermeen N, Willmes, Diana M, Pesta, Dominik, de Cabo, Rafael, O Sullivan, John F, Simon, Eric, Shulman, Gerald I, Hamilton, Bradford S, Birkenfeld, Andreas L
Published in Communications biology (01.07.2021)
Published in Communications biology (01.07.2021)
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Journal Article
Publisher Correction: Deletion of the diabetes candidate gene Slc16a13 in mice attenuates diet-induced ectopic lipid accumulation and insulin resistance
Schumann, Tina, König, Jörg, von Loeffelholz, Christian, Vatner, Daniel F, Zhang, Dongyan, Perry, Rachel J, Bernier, Michel, Chami, Jason, Henke, Christine, Kurzbach, Anica, El-Agroudy, Nermeen N, Willmes, Diana M, Pesta, Dominik, de Cabo, Rafael, O Sullivan, John F, Simon, Eric, Shulman, Gerald I, Hamilton, Bradford S, Birkenfeld, Andreas L
Published in Communications biology (14.07.2021)
Published in Communications biology (14.07.2021)
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Journal Article
Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo
Madiraju, Anila K, Qiu, Yang, Perry, Rachel J, Rahimi, Yasmeen, Zhang, Xian-Man, Zhang, Dongyan, Camporez, João-Paulo G, Cline, Gary W, Butrico, Gina M, Kemp, Bruce E, Casals, Gregori, Steinberg, Gregory R, Vatner, Daniel F, Petersen, Kitt F, Shulman, Gerald I
Published in Nature medicine (01.09.2018)
Published in Nature medicine (01.09.2018)
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Fatty Acid Esterification as a NASH Therapeutic Target
Sakuma, Ikki, Vatner, Daniel F
Published in Cellular and molecular gastroenterology and hepatology (01.01.2024)
Published in Cellular and molecular gastroenterology and hepatology (01.01.2024)
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Metformin, phenformin, and galegine inhibit complex IV activity and reduce glycerol-derived gluconeogenesis
LaMoia, Traci E, Butrico, Gina M, Kalpage, Hasini A, Goedeke, Leigh, Hubbard, Brandon T, Vatner, Daniel F, Gaspar, Rafael C, Zhang, Xian-Man, Cline, Gary W, Nakahara, Keita, Woo, Seungwan, Shimada, Atsuhiro, Hüttemann, Maik, Shulman, Gerald I
Published in Proceedings of the National Academy of Sciences - PNAS (08.03.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (08.03.2022)
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Humanized mouse liver reveals endothelial control of essential hepatic metabolic functions
Kaffe, Eleanna, Roulis, Manolis, Zhao, Jun, Qu, Rihao, Sefik, Esen, Mirza, Haris, Zhou, Jing, Zheng, Yunjiang, Charkoftaki, Georgia, Vasiliou, Vasilis, Vatner, Daniel F., Mehal, Wajahat Z., Yuval Kluger, Flavell, Richard A.
Published in Cell (31.08.2023)
Published in Cell (31.08.2023)
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Hepatic Insulin Resistance Is Not Pathway Selective in Humans With Nonalcoholic Fatty Liver Disease
Ter Horst, Kasper W, Vatner, Daniel F, Zhang, Dongyan, Cline, Gary W, Ackermans, Mariette T, Nederveen, Aart J, Verheij, Joanne, Demirkiran, Ahmet, van Wagensveld, Bart A, Dallinga-Thie, Geesje M, Nieuwdorp, Max, Romijn, Johannes A, Shulman, Gerald I, Serlie, Mireille J
Published in Diabetes care (01.02.2021)
Published in Diabetes care (01.02.2021)
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224-OR: Antisense Oligonucleotide–Mediated Restriction of Mitochondrial Pyruvate Metabolism Limits DNL in High-Fat Fed C57BL6/J Mice
STROBER, JORDAN W., PAOLELLA, LAUREN M., SUH, REBECCA, HUBBARD, BRANDON T., MURRAY, SUE, VATNER, DANIEL F.
Published in Diabetes (New York, N.Y.) (01.06.2022)
Published in Diabetes (New York, N.Y.) (01.06.2022)
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