Biophysical properties of the clinical-stage antibody landscape
Jain, Tushar, Sun, Tingwan, Durand, Stéphanie, Hall, Amy, Houston, Nga Rewa, Nett, Juergen H., Sharkey, Beth, Bobrowicz, Beata, Caffry, Isabelle, Yu, Yao, Cao, Yuan, Lynaugh, Heather, Brown, Michael, Baruah, Hemanta, Gray, Laura T., Krauland, Eric M., Xu, Yingda, Vásquez, Maximiliano, Wittrup, K. Dane
Published in Proceedings of the National Academy of Sciences - PNAS (31.01.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (31.01.2017)
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Journal Article
Prediction of delayed retention of antibodies in hydrophobic interaction chromatography from sequence using machine learning
Jain, Tushar, Boland, Todd, Lilov, Asparouh, Burnina, Irina, Brown, Michael, Xu, Yingda, Vásquez, Maximiliano
Published in Bioinformatics (Oxford, England) (01.12.2017)
Published in Bioinformatics (Oxford, England) (01.12.2017)
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Journal Article
Deamidation and isomerization liability analysis of 131 clinical-stage antibodies
Lu, Xiaojun, Nobrega, R Paul, Lynaugh, Heather, Jain, Tushar, Barlow, Kyle, Boland, Todd, Sivasubramanian, Arvind, Vásquez, Maximiliano, Xu, Yingda
Published in mAbs (02.01.2019)
Published in mAbs (02.01.2019)
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Journal Article
Conformational Energy Calculations on Polypeptides and Proteins
Vasquez, Maximiliano, Nemethy, George, Scheraga, Harold A
Published in Chemical reviews (01.12.1994)
Published in Chemical reviews (01.12.1994)
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Journal Article
High-throughput screening for developability during early-stage antibody discovery using self-interaction nanoparticle spectroscopy
Liu, Yuqi, Caffry, Isabelle, Wu, Jiemin, Geng, Steven B, Jain, Tushar, Sun, Tingwan, Reid, Felicia, Cao, Yuan, Estep, Patricia, Yu, Yao, Vásquez, Maximiliano, Tessier, Peter M, Xu, Yingda
Published in mAbs (01.03.2014)
Published in mAbs (01.03.2014)
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Journal Article
Assessing the binding properties of the anti-PD-1 antibody landscape using label-free biosensors
Brown, Michael E, Bedinger, Daniel, Lilov, Asparouh, Rathanaswami, Palaniswami, Vásquez, Maximiliano, Durand, Stéphanie, Wallace-Moyer, Ian, Zhong, Lihui, Nett, Juergen H, Burnina, Irina, Caffry, Isabelle, Lynaugh, Heather, Sinclair, Melanie, Sun, Tingwan, Bukowski, John, Xu, Yingda, Abdiche, Yasmina Noubia
Published in PloS one (05.03.2020)
Published in PloS one (05.03.2020)
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Journal Article
Antibody-mediated protection against symptomatic COVID-19 can be achieved at low serum neutralizing titers
Schmidt, Pete, Narayan, Kristin, Li, Yong, Kaku, Chengzi I, Brown, Michael E, Champney, Elizabeth, Geoghegan, James C, Vásquez, Maximiliano, Krauland, Eric M, Yockachonis, Thomas, Bai, Shuangyi, Gunn, Bronwyn M, Cammarata, Anthony, Rubino, Christopher M, Ambrose, Paul, Walker, Laura M
Published in Science translational medicine (22.03.2023)
Published in Science translational medicine (22.03.2023)
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Journal Article
Addressing polyspecificity of antibodies selected from an in vitro yeast presentation system: a FACS-based, high-throughput selection and analytical tool
Xu, Yingda, Roach, William, Sun, Tingwan, Jain, Tushar, Prinz, Bianka, Yu, Ta-Yi, Torrey, Joshua, Thomas, Jerry, Bobrowicz, Piotr, Vásquez, Maximiliano, Wittrup, K. Dane, Krauland, Eric
Published in Protein engineering, design and selection (01.10.2013)
Published in Protein engineering, design and selection (01.10.2013)
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Journal Article
Connecting the sequence dots: shedding light on the genesis of antibodies reported to be designed in silico
Vásquez, Maximiliano, Krauland, Eric, Walker, Laura, Wittrup, Dane, Gerngross, Tillman
Published in mAbs (04.07.2019)
Published in mAbs (04.07.2019)
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Journal Article
High throughput cross-interaction measures for human IgG1 antibodies correlate with clearance rates in mice
Kelly, Ryan L, Sun, Tingwan, Jain, Tushar, Caffry, Isabelle, Yu, Yao, Cao, Yuan, Lynaugh, Heather, Brown, Michael, Vásquez, Maximiliano, Wittrup, K Dane, Xu, Yingda
Published in mAbs (04.07.2015)
Published in mAbs (04.07.2015)
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Journal Article
An alternative assay to hydrophobic interaction chromatography for high-throughput characterization of monoclonal antibodies
Estep, Patricia, Caffry, Isabelle, Yu, Yao, Sun, Tingwan, Cao, Yuan, Lynaugh, Heather, Jain, Tushar, Vásquez, Maximiliano, Tessier, Peter M, Xu, Yingda
Published in mAbs (04.05.2015)
Published in mAbs (04.05.2015)
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Journal Article
Coordinate Expression and Functional Profiling Identify an Extracellular Proteolytic Signaling Pathway
Bhatt, Ami S., Welm, Alana, Farady, Christopher J., Vásquez, Maximiliano, Wilson, Keith, Craik, Charles S.
Published in Proceedings of the National Academy of Sciences - PNAS (03.04.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (03.04.2007)
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Journal Article
Broad epitope coverage of a human in vitro antibody library
Sivasubramanian, Arvind, Estep, Patricia, Lynaugh, Heather, Yu, Yao, Miles, Adam, Eckman, Josh, Schutz, Kevin, Piffath, Crystal, Boland, Nadthakarn, Niles, Rebecca Hurley, Durand, Stéphanie, Boland, Todd, Vásquez, Maximiliano, Xu, Yingda, Abdiche, Yasmina
Published in mAbs (01.01.2017)
Published in mAbs (01.01.2017)
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Journal Article
The uniqueness of flow in probing the aggregation behavior of clinically relevant antibodies
Willis, Leon F., Kumar, Amit, Jain, Tushar, Caffry, Isabelle, Xu, Yingda, Radford, Sheena E., Kapur, Nikil, Vásquez, Maximiliano, Brockwell, David J.
Published in Engineering reports (Hoboken, N.J.) (01.05.2020)
Published in Engineering reports (Hoboken, N.J.) (01.05.2020)
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