IL-7 receptor blockade blunts antigen-specific memory T cell responses and chronic inflammation in primates
Belarif, Lyssia, Mary, Caroline, Jacquemont, Lola, Mai, Hoa Le, Danger, Richard, Hervouet, Jeremy, Minault, David, Thepenier, Virginie, Nerrière-Daguin, Veronique, Nguyen, Elisabeth, Pengam, Sabrina, Largy, Eric, Delobel, Arnaud, Martinet, Bernard, Le Bas-Bernardet, Stéphanie, Brouard, Sophie, Soulillou, Jean-Paul, Degauque, Nicolas, Blancho, Gilles, Vanhove, Bernard, Poirier, Nicolas
Published in Nature communications (26.10.2018)
Published in Nature communications (26.10.2018)
Get full text
Journal Article
Anti-SARS-CoV-2 glyco-humanized polyclonal antibody XAV-19: phase II/III randomized placebo-controlled trial shows acceleration to recovery for mild to moderate patients with COVID-19
Poulakou, Garyfallia, Royer, Pierre-Joseph, Evgeniev, Nikolay, Evanno, Gwénaëlle, Shneiker, Françoise, Marcelin, Anne-Geneviève, Vanhove, Bernard, Duvaux, Odile, Marot, Stéphane, Calvez, Vincent
Published in Frontiers in immunology (17.04.2024)
Published in Frontiers in immunology (17.04.2024)
Get full text
Journal Article
Cystathionine‐gamma‐lyase overexpression in T cells enhances antitumor effect independently of cysteine autonomy
Lancien, Melanie, Gueno, Lucile, Salle, Sonia, Merieau, Emmanuel, Beriou, Gaelle, Nguyen, Tuan H., Abidi, Ahmed, Dilek, Nahzli, Solomon, Pierre, Poschmann, Jeremie, Michielin, Olivier, Vuillefroy de Silly, Romain, Vanhove, Bernard, Louvet, Cedric
Published in Cancer science (01.05.2021)
Published in Cancer science (01.05.2021)
Get full text
Journal Article
Targeting CD28, CTLA-4 and PD-L1 costimulation differentially controls immune synapses and function of human regulatory and conventional T-cells
Dilek, Nahzli, Poirier, Nicolas, Hulin, Philippe, Coulon, Flora, Mary, Caroline, Ville, Simon, Vie, Henri, Clémenceau, Béatrice, Blancho, Gilles, Vanhove, Bernard
Published in PloS one (23.12.2013)
Published in PloS one (23.12.2013)
Get full text
Journal Article
Prevention of lupus nephritis development in NZB/NZW mice by selective blockade of CD28
Laurent, Laetitia, Le Fur, Awena, Le Bloas, Rozenn, Néel, Mélanie, Mary, Caroline, Moreau, Anne, Poirier, Nicolas, Vanhove, Bernard, Fakhouri, Fadi
Published in European journal of immunology (01.08.2017)
Published in European journal of immunology (01.08.2017)
Get full text
Journal Article
Corrigendum: XAV-19, a swine glyco-humanized polyclonal antibody against SARS-CoV-2 spike receptor-binding domain, targets multiple epitopes and broadly neutralizes variants
Vanhove, Bernard, Marot, Stéphane, So, Ray T, Gaborit, Benjamin, Evanno, Gwénaëlle, Malet, Isabelle, Lafrogne, Guillaume, Mevel, Edwige, Ciron, Carine, Royer, Pierre-Joseph, Lheriteau, Elsa, Raffi, François, Bruzzone, Roberto, Mok, Chris Ka Pun, Duvaux, Odile, Marcelin, Anne-Geneviève, Calvez, Vincent
Published in Frontiers in immunology (28.04.2023)
Published in Frontiers in immunology (28.04.2023)
Get full text
Journal Article
Inducing CTLA-4-dependent immune regulation by selective CD28 blockade promotes regulatory T cells in organ transplantation
Poirier, Nicolas, Azimzadeh, Agnes M, Zhang, Tianshu, Dilek, Nahzli, Mary, Caroline, Nguyen, Bao, Tillou, Xavier, Wu, Guosheng, Reneaudin, Karine, Hervouet, Jeremy, Martinet, Bernard, Coulon, Flora, Allain-Launay, Emma, Karam, Georges, Soulillou, Jean-Paul, Pierson, 3rd, Richard N, Blancho, Gilles, Vanhove, Bernard
Published in Science translational medicine (03.02.2010)
Published in Science translational medicine (03.02.2010)
Get more information
Journal Article
XAV-19, a Swine Glyco-Humanized Polyclonal Antibody Against SARS-CoV-2 Spike Receptor-Binding Domain, Targets Multiple Epitopes and Broadly Neutralizes Variants
Vanhove, Bernard, Marot, Stéphane, So, Ray T, Gaborit, Benjamin, Evanno, Gwénaëlle, Malet, Isabelle, Lafrogne, Guillaume, Mevel, Edwige, Ciron, Carine, Royer, Pierre-Joseph, Lheriteau, Elsa, Raffi, François, Bruzzone, Roberto, Mok, Chris Ka Pun, Duvaux, Odile, Marcelin, Anne-Geneviève, Calvez, Vincent
Published in Frontiers in immunology (15.11.2021)
Published in Frontiers in immunology (15.11.2021)
Get full text
Journal Article
LIS1, a glyco-humanized swine polyclonal anti-lymphocyte globulin, as a novel induction treatment in solid organ transplantation
Rousse, Juliette, Royer, Pierre-Joseph, Evanno, Gwénaëlle, Lheriteau, Elsa, Ciron, Carine, Salama, Apolline, Shneiker, Françoise, Duchi, Roberto, Perota, Andrea, Galli, Cesare, Cozzi, Emmanuele, Blancho, Gilles, Duvaux, Odile, Brouard, Sophie, Soulillou, Jean-Paul, Bach, Jean-Marie, Vanhove, Bernard
Published in Frontiers in immunology (16.02.2023)
Published in Frontiers in immunology (16.02.2023)
Get full text
Journal Article
CD28 Costimulation of T Helper 1 Cells Enhances Cytokine Release In Vivo
Langenhorst, Daniela, Haack, Stephanie, Göb, Selina, Uri, Anna, Lühder, Fred, Vanhove, Bernard, Hünig, Thomas, Beyersdorf, Niklas
Published in Frontiers in immunology (16.05.2018)
Published in Frontiers in immunology (16.05.2018)
Get full text
Journal Article
Mesenchymal stem cells induce a weak immune response in the rat striatum after allo or xenotransplantation
Rossignol, Julien, Boyer, Cécile, Thinard, Reynald, Remy, Séverine, Dugast, Anne‐Sophie, Dubayle, David, Dey, Nicolas D., Boeffard, Françoise, Delecrin, Joël, Heymann, Dominique, Vanhove, Bernard, Anegon, Ignacio, Naveilhan, Philippe, Dunbar, Gary L., Lescaudron, Laurent
Published in Journal of cellular and molecular medicine (02.08.2009)
Published in Journal of cellular and molecular medicine (02.08.2009)
Get full text
Journal Article
Novel CD28 antagonist mPEG PV1-Fab' mitigates experimental autoimmune uveitis by suppressing CD4+ T lymphocyte activation and IFN-γ production
Papotto, Pedro Henrique, Marengo, Eliana Blini, Sardinha, Luiz Roberto, Carvalho, Karina Inácio, de Carvalho, Ana Eduarda Zulim, Castillo-Mendez, Sheyla, Jank, Carina Calixto, Vanhove, Bernard, Goldberg, Anna Carla, Rizzo, Luiz Vicente
Published in PloS one (01.03.2017)
Published in PloS one (01.03.2017)
Get full text
Journal Article
CD28 Blockade Ex Vivo Induces Alloantigen-Specific Immune Tolerance but Preserves T-Cell Pathogen Reactivity
Dillinger, Barbara, Ahmadi-Erber, Sarah, Soukup, Klara, Halfmann, Angela, Schrom, Silke, Vanhove, Bernard, Steinberger, Peter, Geyeregger, Rene, Ladisch, Stephan, Dohnal, Alexander Michael
Published in Frontiers in immunology (20.09.2017)
Published in Frontiers in immunology (20.09.2017)
Get full text
Journal Article
Graft versus host disease in humanized mice is differentially controlled by CD28 and CD80/86 antagonists
Poirier, Nicolas, Dilek, Nahzli, Mary, Caroline, Vanhove, Bernard
Published in Journal of Translational Medicine (28.11.2012)
Published in Journal of Translational Medicine (28.11.2012)
Get full text
Journal Article
Conference Proceeding
Concerted BAG3 and SIRPα blockade impairs pancreatic tumor growth
De Marco, Margot, Gauttier, Vanessa, Pengam, Sabrina, Mary, Caroline, Ranieri, Bianca, Basile, Anna, Festa, Michela, Falco, Antonia, Reppucci, Francesca, Cammarota, Anna Lisa, Acernese, Fausto, De Laurenzi, Vincenzo, Sala, Gianluca, Brongo, Sergio, Miyasaka, Masayuki, Shalapour, Shabnam, Vanhove, Bernard, Poirier, Nicolas, Iaccarino, Roberta, Karin, Michael, Turco, Maria Caterina, Rosati, Alessandra, Marzullo, Liberato
Published in Cell death discovery (03.03.2022)
Published in Cell death discovery (03.03.2022)
Get full text
Journal Article
Differential regulation of motility and immune synapses by CD28/ CTLA-4 costimulation in effector and regulatory T cells
Dilek, Nahzli, Poirier, Nicolas, Hulin, Philippe, Blancho, Gilles, Vanhove, Bernard
Published in Journal of Translational Medicine (28.11.2012)
Published in Journal of Translational Medicine (28.11.2012)
Get full text
Journal Article
Conference Proceeding
Antagonist Anti-CD28 Therapeutics for the Treatment of Autoimmune Disorders
Vanhove, Bernard, Poirier, Nicolas, Fakhouri, Fadi, Laurent, Laetitia, ’t Hart, Bert, Papotto, Pedro, Rizzo, Luiz, Zaitsu, Masaaki, Issa, Fadi, Wood, Kathryn, Soulillou, Jean-Paul, Blancho, Gilles
Published in Antibodies (Basel) (01.12.2017)
Published in Antibodies (Basel) (01.12.2017)
Get full text
Journal Article
Antagonist properties of monoclonal antibodies to human CD28: role of valency and heavy-chain constant domain
Mary, Caroline, Coulon, Flora, Poirier, Nicolas, Dilek, Nahzli, Martinet, Bernard, Blancho, Gilles, Vanhove, Bernard
Published in Journal of translational medicine (28.11.2012)
Published in Journal of translational medicine (28.11.2012)
Get full text
Journal Article
Control of transplant tolerance and intragraft regulatory T cell localization by CCL5
Dilek, Nahzli, Poirier, Nicolas, Usal, Claire, Martinet, Bernard, Blancho, Gilles, Vanhove, Bernard
Published in Journal of Translational Medicine (28.11.2012)
Published in Journal of Translational Medicine (28.11.2012)
Get full text
Journal Article
Conference Proceeding