Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti-tau antibody AT8
Malia, Thomas J., Teplyakov, Alexey, Ernst, Robin, Wu, Sheng-Jiun, Lacy, Eilyn R., Liu, Xuesong, Vandermeeren, Marc, Mercken, Marc, Luo, Jinquan, Sweet, Raymond W., Gilliland, Gary L.
Published in Proteins, structure, function, and bioinformatics (01.04.2016)
Published in Proteins, structure, function, and bioinformatics (01.04.2016)
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Passive immunotherapy with a novel antibody against 3pE-modified Aβ demonstrates potential for enhanced efficacy and favorable safety in combination with BACE inhibitor treatment in plaque-depositing mice
Janssens, Jonathan, Hermans, Bart, Vandermeeren, Marc, Barale-Thomas, Erio, Borgers, Marianne, Willems, Roland, Meulders, Greet, Wintmolders, Cindy, Van den Bulck, Dries, Bottelbergs, Astrid, Ver Donck, Luc, Larsen, Peter, Moechars, Dieder, Edwards, Wilson, Mercken, Marc, Van Broeck, Bianca
Published in Neurobiology of disease (01.07.2021)
Published in Neurobiology of disease (01.07.2021)
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NLRP3 inflammasome activation and pyroptosis are dispensable for tau pathology
Paesmans, Ine, Van Kolen, Kristof, Vandermeeren, Marc, Shih, Pei-Yu, Wuyts, Dirk, Boone, Fleur, Garcia Sanchez, Sergio, Grauwen, Karolien, Van Hauwermeiren, Filip, Van Opdenbosch, Nina, Lamkanfi, Mohamed, van Loo, Geert, Bottelbergs, Astrid
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Published in Frontiers in aging neuroscience (24.09.2024)
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Macrocyclic BACE inhibitors: Optimization of a micromolar hit to nanomolar leads
Huang, Yifang, Strobel, Eric D., Ho, Chih Y., Reynolds, Charles H., Conway, Kelly A., Piesvaux, Jennifer A., Brenneman, Douglas E., Yohrling, George J., Moore Arnold, H., Rosenthal, Daniel, Alexander, Richard S., Tounge, Brett A., Mercken, Marc, Vandermeeren, Marc, Parker, Michael H., Reitz, Allen B., Baxter, Ellen W.
Published in Bioorganic & medicinal chemistry letters (15.05.2010)
Published in Bioorganic & medicinal chemistry letters (15.05.2010)
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Reduction of Aβ Levels in the Sprague Dawley Rat After Oral Administration of the Functional g-Secretase Inhibitor, DAPT: A Novel Non- Transgenic Model for Aβ Production Inhibitors
Mouedden, Mohammed, Vandermeeren, Marc, Meert, Theo, Mercken, Marc
Published in Current pharmaceutical design (01.02.2006)
Published in Current pharmaceutical design (01.02.2006)
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Development and Characterization of Mouse-Specific Anti-Tau Monoclonal Antibodies: Relevance for Analysis of Murine Tau in Cerebrospinal Fluid
Rodrigues Martins, Dina, Vandermeeren, Marc, Van Kolen, Kristof, Brepoels, Eddy, Borgers, Marianne, Wintmolders, Cindy, Delay, Charlotte, Bottelbergs, Astrid, Mercken, Marc, Theunis, Clara
Published in Journal of Alzheimer's disease (01.01.2023)
Published in Journal of Alzheimer's disease (01.01.2023)
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Anti-Tau Monoclonal Antibodies Derived from Soluble and Filamentous Tau Show Diverse Functional Properties in vitro and in vivo
Vandermeeren, Marc, Borgers, Marianne, Van Kolen, Kristof, Theunis, Clara, Vasconcelos, Bruno, Bottelbergs, Astrid, Wintmolders, Cindy, Daneels, Guy, Willems, Roland, Dockx, Koen, Delbroek, Lore, Marreiro, André, Ver Donck, Luc, Sousa, Cristiano, Nanjunda, Rupesh, Lacy, Eilyn, Van De Casteele, Tom, Van Dam, Debby, De Deyn, Peter Paul, Kemp, John A, Malia, Thomas J, Mercken, Marc H
Published in Journal of Alzheimer's disease (01.01.2018)
Published in Journal of Alzheimer's disease (01.01.2018)
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Discovery and Functional Characterization of hPT3, a Humanized Anti-Phospho Tau Selective Monoclonal Antibody
Van Kolen, Kristof, Malia, Thomas J, Theunis, Clara, Nanjunda, Rupesh, Teplyakov, Alexey, Ernst, Robin, Wu, Sheng-Jiun, Luo, Jinquan, Borgers, Marianne, Vandermeeren, Marc, Bottelbergs, Astrid, Wintmolders, Cindy, Lacy, Eilyn, Maurin, Hervé, Larsen, Peter, Willems, Roland, Van De Casteele, Tom, Triana-Baltzer, Gallen, Slemmon, Randy, Galpern, Wendy, Trojanowski, John Q, Sun, Hong, Mercken, Marc H
Published in Journal of Alzheimer's disease (01.01.2020)
Published in Journal of Alzheimer's disease (01.01.2020)
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ANTI-TAU ANTIBODY PROFILING FOR PASSIVE IMMUNIZATION THERAPY: COMPARING SEEDS DERIVED FROM TRANSGENIC ANIMALS AND HUMAN BRAIN TISSUE
Borgers, Marianne, Dockx, Koen, Van de Weyer, Inez, Versweyveld, Sofie, De Waepenaert, Katja, Vandermeeren, Marc, Van Kolen, Kristof, Vanhoof, Greet, Ebneth, Andreas, Mercken, Marc
Published in Alzheimer's & dementia (01.07.2017)
Published in Alzheimer's & dementia (01.07.2017)
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MOLECULAR ANALYSIS OF TAU IN RODENT AND NON-RODENT MODELS OF AD
Marreiro, Andre, Van Kolen, Kristof, Plasman, Kim, Depuydt, Geert, Peeraer, Eve, Daneels, Guy, Fierens, Katleen, Temmerman, Liesbet, Vandermeeren, Marc, Hermans, Bart, De Deyn, Peter Paul, Engelborghs, Sebastiaan, Gevaert, Kris, Moechars, Diederik, Mercken, Marc
Published in Alzheimer's & dementia (01.07.2014)
Published in Alzheimer's & dementia (01.07.2014)
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P3‐059: MOLECULAR ANALYSIS OF TAU IN RODENT AND NON‐RODENT MODELS OF AD
Marreiro, Andre, Kolen, Kristof, Plasman, Kim, Depuydt, Geert, Peeraer, Eve, Daneels, Guy, Fierens, Katleen, Temmerman, Liesbet, Vandermeeren, Marc, Hermans, Bart, De Deyn, Peter Paul, Engelborghs, Sebastiaan, Gevaert, Kris, Moechars, Diederik, Mercken, Marc
Published in Alzheimer's & dementia (01.07.2014)
Published in Alzheimer's & dementia (01.07.2014)
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P2‐445: Quantification of beta‐amyloid ï€ peptides in dog CSF following gamma‐secretase modulator and inhibitor treatment
Barao, Ana, Van Broeck, Bianca, Vandermeeren, Marc, Clessens, Ellen, Borghys, Herman, Karran, Eric, Mercken, Marc
Published in Alzheimer's & dementia (01.07.2011)
Published in Alzheimer's & dementia (01.07.2011)
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Journal Article
Quantification of beta-amyloid ï€ peptides in dog CSF following gamma-secretase modulator and inhibitor treatment
Barao, Ana, Van Broeck, Bianca, Vandermeeren, Marc, Clessens, Ellen, Borghys, Herman, Karran, Eric, Mercken, Marc
Published in Alzheimer's & dementia (01.07.2011)
Published in Alzheimer's & dementia (01.07.2011)
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Reduction of A[beta] Levels in the Sprague Dawley Rat After Oral Administration of the Functional g-Secretase Inhibitor, DAPT: A Novel Non- Transgenic Model for A[beta] Production Inhibitors
Mouedden, Mohammed E, Vandermeeren, Marc, Meert, Theo, Mercken, Marc
Published in Current pharmaceutical design (01.02.2006)
Published in Current pharmaceutical design (01.02.2006)
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Journal Article
Reduction of Abeta levels in the Sprague Dawley rat after oral administration of the functional gamma-secretase inhibitor, DAPT: a novel non-transgenic model for Abeta production inhibitors
El Mouedden, Mohammed, Vandermeeren, Marc, Meert, Theo, Mercken, Marc
Published in Current pharmaceutical design (2006)
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Published in Current pharmaceutical design (2006)
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ANTI-PHF-TAU ANTIBODIES AND THEIR USE
JANECKI DARIUSZ, MURDOCK MELISSA, VANDERMEEREN MARC, MALIA THOMAS, WU SHENG JIUN, LIU XUESONG, MERCKEN MARC, ALDERFER CHRISTOPHER
Year of Publication 04.09.2014
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Year of Publication 04.09.2014
Patent
Dimethylfumarate is an Inhibitor of Cytokine-Induced Nuclear Translocation of NF-κB1, But Not RelA in Normal Human Dermal Fibroblast Cells
Borgers, Marcel, Beyaert, Rudi, Borghmans, Inge, Vandermeeren, Marc, Geysen, Johan, Wouters, Hilde, Janssens, Sophie
Published in Journal of investigative dermatology (01.01.2001)
Published in Journal of investigative dermatology (01.01.2001)
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