Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells
McBrien, Julia Bergild, Mavigner, Maud, Franchitti, Lavinia, Smith, S. Abigail, White, Erick, Tharp, Gregory K., Walum, Hasse, Busman-Sahay, Kathleen, Aguilera-Sandoval, Christian R., Thayer, William O., Spagnuolo, Rae Ann, Kovarova, Martina, Wahl, Angela, Cervasi, Barbara, Margolis, David M., Vanderford, Thomas H., Carnathan, Diane G., Paiardini, Mirko, Lifson, Jeffrey D., Lee, John H., Safrit, Jeffrey T., Bosinger, Steven E., Estes, Jacob D., Derdeyn, Cynthia A., Garcia, J. Victor, Kulpa, Deanna A., Chahroudi, Ann, Silvestri, Guido
Published in Nature (London) (06.02.2020)
Published in Nature (London) (06.02.2020)
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Natural SIV Hosts: Showing AIDS the Door
Chahroudi, Ann, Bosinger, Steven E., Vanderford, Thomas H., Paiardini, Mirko, Silvestri, Guido
Published in Science (American Association for the Advancement of Science) (09.03.2012)
Published in Science (American Association for the Advancement of Science) (09.03.2012)
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Enhancing SIV-specific immunity in vivo by PD-1 blockade
Vanderford, Thomas H, Velu, Vijayakumar, Titanji, Kehmia, Ahmed, Rafi, Amara, Rama Rao, Lai, Lilin, Pladevega, Annette, Freeman, Gordon J, Husain, Sajid, Zhu, Baogong, Chennareddi, Lakshmi, Silvestri, Guido
Published in Nature (12.03.2009)
Published in Nature (12.03.2009)
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CD8+ Lymphocytes Are Required for Maintaining Viral Suppression in SIV-Infected Macaques Treated with Short-Term Antiretroviral Therapy
Cartwright, Emily K., Spicer, Lori, Smith, S. Abigail, Lee, David, Fast, Randy, Paganini, Sara, Lawson, Benton O., Nega, Melon, Easley, Kirk, Schmitz, Joern E., Bosinger, Steven E., Paiardini, Mirko, Chahroudi, Ann, Vanderford, Thomas H., Estes, Jacob D., Lifson, Jeffrey D., Derdeyn, Cynthia A., Silvestri, Guido
Published in Immunity (Cambridge, Mass.) (20.09.2016)
Published in Immunity (Cambridge, Mass.) (20.09.2016)
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SARS-CoV-2 RBD trimer protein adjuvanted with Alum-3M-052 protects from SARS-CoV-2 infection and immune pathology in the lung
Routhu, Nanda Kishore, Cheedarla, Narayanaiah, Bollimpelli, Venkata Satish, Gangadhara, Sailaja, Edara, Venkata Viswanadh, Lai, Lilin, Sahoo, Anusmita, Shiferaw, Ayalnesh, Styles, Tiffany M., Floyd, Katharine, Fischinger, Stephanie, Atyeo, Caroline, Shin, Sally A., Gumber, Sanjeev, Kirejczyk, Shannon, Dinnon, Kenneth H., Shi, Pei-Yong, Menachery, Vineet D., Tomai, Mark, Fox, Christopher B., Alter, Galit, Vanderford, Thomas H., Gralinski, Lisa, Suthar, Mehul S., Amara, Rama Rao
Published in Nature communications (11.06.2021)
Published in Nature communications (11.06.2021)
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Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys
Bosinger, Steven E, Li, Qingsheng, Gordon, Shari N, Klatt, Nichole R, Duan, Lijie, Xu, Luoling, Francella, Nicholas, Sidahmed, Abubaker, Smith, Anthony J, Cramer, Elizabeth M, Zeng, Ming, Masopust, David, Carlis, John V, Ran, Longsi, Vanderford, Thomas H, Paiardini, Mirko, Isett, R Benjamin, Baldwin, Don A, Else, James G, Staprans, Silvija I, Silvestri, Guido, Haase, Ashley T, Kelvin, David J
Published in The Journal of clinical investigation (01.12.2009)
Published in The Journal of clinical investigation (01.12.2009)
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Replicative fitness of transmitted HIV-1 drives acute immune activation, proviral load in memory CD4⁺ T cells, and disease progression
Claiborne, Daniel T., Prince, Jessica L., Scully, Eileen, Macharia, Gladys, Micci, Luca, Lawson, Benton, Kopycinski, Jakub, Deymier, Martin J., Vanderford, Thomas H., Nganou-Makamdop, Krystelle, Ende, Zachary, Brooks, Kelsie, Tang, Jianming, Yu, Tianwei, Lakhi, Shabir, Kilembe, William, Silvestri, Guido, Douek, Daniel, Goepfert, Paul A., Price, Matthew A., Allen, Susan A., Paiardini, Mirko, Altfeld, Marcus, Gilmour, Jill, Hunter, Eric
Published in Proceedings of the National Academy of Sciences - PNAS (24.03.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (24.03.2015)
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Target cell availability, rather than breast milk factors, dictates mother-to-infant transmission of SIV in sooty mangabeys and rhesus macaques
Chahroudi, Ann, Cartwright, Emily, Lee, S Thera, Mavigner, Maud, Carnathan, Diane G, Lawson, Benton, Carnathan, Paul M, Hashempoor, Tayebeh, Murphy, Megan K, Meeker, Tracy, Ehnert, Stephanie, Souder, Christopher, Else, James G, Cohen, Joyce, Collman, Ronald G, Vanderford, Thomas H, Permar, Sallie R, Derdeyn, Cynthia A, Villinger, Francois, Silvestri, Guido
Published in PLoS pathogens (01.03.2014)
Published in PLoS pathogens (01.03.2014)
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Dynamics of Simian Immunodeficiency Virus SIVmac239 Infection in Pigtail Macaques
KLATT, Nlchole R, CANARY, Lauren A, SILVESTRI, Guido, BRENCHLEY, Jason M, VANDERFORD, Thomas H, VINTON, Caroi L, ENGRAM, Jessica C, DUNHAM, Richard M, CRONISE, Heather E, SWERCZEK, Joanna M, LAFONT, Bernard A. P, PICKER, Louis J
Published in Journal of Virology (01.01.2012)
Published in Journal of Virology (01.01.2012)
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Intact type I Interferon production and IRF7 function in sooty mangabeys
Bosinger, Steven E, Johnson, Zachary P, Folkner, Kathryn A, Patel, Nirav, Hashempour, Tayebeh, Jochems, Simon P, Del Rio Estrada, Perla M, Paiardini, Mirko, Lin, Rongtuan, Vanderford, Thomas H, Hiscott, John, Silvestri, Guido
Published in PLoS pathogens (01.08.2013)
Published in PLoS pathogens (01.08.2013)
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Analysis of the In Vivo Turnover of CD4+ T-Cell Subsets in Chronically SIV-Infected Sooty Mangabeys
Ortiz, Alexandra M, Carnathan, Diane G, Yu, Joana, Sheehan, Katherine M, Kim, Peter, Reynaldi, Arnold, Vanderford, Thomas H, Klatt, Nichole R, Brenchley, Jason M, Davenport, Miles P, Silvestri, Guido
Published in PloS one (26.05.2016)
Published in PloS one (26.05.2016)
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Dynamics and origin of rebound viremia in SHIV-infected infant macaques following interruption of long-term ART
Obregon-Perko, Veronica, Bricker, Katherine M, Mensah, Gloria, Uddin, Ferzan, Rotolo, Laura, Vanover, Daryll, Desai, Yesha, Santangelo, Philip J, Jean, Sherrie, Wood, Jennifer S, Connor-Stroud, Fawn C, Ehnert, Stephanie, Berendam, Stella J, Liang, Shan, Vanderford, Thomas H, Bar, Katharine J, Shaw, George M, Silvestri, Guido, Kumar, Amit, Fouda, Genevieve G, Permar, Sallie R, Chahroudi, Ann
Published in JCI insight (08.12.2021)
Published in JCI insight (08.12.2021)
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Cloning and Analysis of Sooty Mangabey Alternative Coreceptors That Support Simian Immunodeficiency Virus SIVsmm Entry Independently of CCR5
ELLIOTT, Sarah T. C, RIDDICK, Nadeene E, COLLMAN, Ronald G, FRANCELLA, Nicholas, PAIARDINI, Mirko, VANDERFORD, Thomas H, BING LI, APETREI, Cristian, SODORA, Donald L, DERDEYN, Cynthia A, SILVESTRI, Guido
Published in Journal of Virology (01.01.2012)
Published in Journal of Virology (01.01.2012)
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Viral CTL escape mutants are generated in lymph nodes and subsequently become fixed in plasma and rectal mucosa during acute SIV infection of macaques
Vanderford, Thomas H, Bleckwehl, Chelsea, Engram, Jessica C, Dunham, Richard M, Klatt, Nichole R, Feinberg, Mark B, Garber, David A, Betts, Michael R, Silvestri, Guido
Published in PLoS pathogens (01.05.2011)
Published in PLoS pathogens (01.05.2011)
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Systemic HIV and SIV latency reversal via non-canonical NF-κB signalling in vivo
Nixon, Christopher C., Mavigner, Maud, Sampey, Gavin C., Brooks, Alyssa D., Spagnuolo, Rae Ann, Irlbeck, David M., Mattingly, Cameron, Ho, Phong T., Schoof, Nils, Cammon, Corinne G., Tharp, Greg K., Kanke, Matthew, Wang, Zhang, Cleary, Rachel A., Upadhyay, Amit A., De, Chandrav, Wills, Saintedym R., Falcinelli, Shane D., Galardi, Cristin, Walum, Hasse, Schramm, Nathaniel J., Deutsch, Jennifer, Lifson, Jeffrey D., Fennessey, Christine M., Keele, Brandon F., Jean, Sherrie, Maguire, Sean, Liao, Baolin, Browne, Edward P., Ferris, Robert G., Brehm, Jessica H., Favre, David, Vanderford, Thomas H., Bosinger, Steven E., Jones, Corbin D., Routy, Jean-Pierre, Archin, Nancie M., Margolis, David M., Wahl, Angela, Dunham, Richard M., Silvestri, Guido, Chahroudi, Ann, Garcia, J. Victor
Published in Nature (London) (06.02.2020)
Published in Nature (London) (06.02.2020)
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Combination of CD8β Depletion and Interleukin-15 Superagonist N-803 Induces Virus Reactivation in Simian-Human Immunodeficiency Virus-Infected, Long-Term ART-Treated Rhesus Macaques
McBrien, Julia B, Wong, Andrew K H, White, Erick, Carnathan, Diane G, Lee, John H, Safrit, Jeffrey T, Vanderford, Thomas H, Paiardini, Mirko, Chahroudi, Ann, Silvestri, Guido
Published in Journal of virology (15.09.2020)
Published in Journal of virology (15.09.2020)
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A modified vaccinia Ankara vector-based vaccine protects macaques from SARS-CoV-2 infection, immune pathology, and dysfunction in the lungs
Routhu, Nanda Kishore, Cheedarla, Narayanaiah, Gangadhara, Sailaja, Bollimpelli, Venkata Satish, Boddapati, Arun K., Shiferaw, Ayalnesh, Rahman, Sheikh Abdul, Sahoo, Anusmita, Edara, Venkata Viswanadh, Lai, Lilin, Floyd, Katharine, Wang, Shelly, Fischinger, Stephanie, Atyeo, Caroline, Shin, Sally A., Gumber, Sanjeev, Kirejczyk, Shannon, Cohen, Joyce, Jean, Sherrie M., Wood, Jennifer S., Connor-Stroud, Fawn, Stammen, Rachelle L., Upadhyay, Amit A., Pellegrini, Kathryn, Montefiori, David, Shi, Pei-Yong, Menachery, Vineet D., Alter, Galit, Vanderford, Thomas H., Bosinger, Steven E., Suthar, Mehul S., Amara, Rama Rao
Published in Immunity (Cambridge, Mass.) (09.03.2021)
Published in Immunity (Cambridge, Mass.) (09.03.2021)
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Transmission and Protection against Reinfection in the Ferret Model with the SARS-CoV-2 USA-WA1/2020 Reference Isolate
Patel, Devanshi R, Field, Cassandra J, Septer, Kayla M, Sim, Derek G, Jones, Matthew J, Heinly, Talia A, Vanderford, Thomas H, McGraw, Elizabeth A, Sutton, Troy C
Published in Journal of virology (10.06.2021)
Published in Journal of virology (10.06.2021)
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Simian Immunodeficiency Virus Persistence in Cellular and Anatomic Reservoirs in Antiretroviral Therapy-Suppressed Infant Rhesus Macaques
Mavigner, Maud, Habib, Jakob, Deleage, Claire, Rosen, Elias, Mattingly, Cameron, Bricker, Katherine, Kashuba, Angela, Amblard, Franck, Schinazi, Raymond F, Lawson, Benton, Vanderford, Thomas H, Jean, Sherrie, Cohen, Joyce, McGary, Colleen, Paiardini, Mirko, Wood, Matthew P, Sodora, Donald L, Silvestri, Guido, Estes, Jacob, Chahroudi, Ann
Published in Journal of virology (15.09.2018)
Published in Journal of virology (15.09.2018)
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Immune activation alters cellular and humoral responses to yellow fever 17D vaccine
Muyanja, Enoch, Ssemaganda, Aloysius, Ngauv, Pearline, Cubas, Rafael, Perrin, Helene, Srinivasan, Divya, Canderan, Glenda, Lawson, Benton, Kopycinski, Jakub, Graham, Amanda S, Rowe, Dawne K, Smith, Michaela J, Isern, Sharon, Michael, Scott, Silvestri, Guido, Vanderford, Thomas H, Castro, Erika, Pantaleo, Giuseppe, Singer, Joel, Gillmour, Jill, Kiwanuka, Noah, Nanvubya, Annet, Schmidt, Claudia, Birungi, Josephine, Cox, Josephine, Haddad, Elias K, Kaleebu, Pontiano, Fast, Patricia, Sekaly, Rafick-Pierre, Trautmann, Lydie, Gaucher, Denis
Published in The Journal of clinical investigation (01.07.2014)
Published in The Journal of clinical investigation (01.07.2014)
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