Synthesis and Glycosidase Inhibition of the Enantiomer of (−)-Steviamine, the First Example of a New Class of Indolizidine Alkaloid
Hu, Xiang-Guo, Bartholomew, Barbara, Nash, Robert J., Wilson, Francis X., Fleet, George W. J., Nakagawa, Shinpei, Kato, Atsushi, Jia, Yue-Mei, Well, Renate van, Yu, Chu-Yi
Published in Organic letters (04.06.2010)
Published in Organic letters (04.06.2010)
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Journal Article
From Solution Phase to “On-Column” Chemistry: Trichloroacetimidate-Based Glycosylation Promoted by Perchloric Acid−Silica
Mukhopadhyay, Balaram, Maurer, Sarah V, Rudolph, Nadine, van Well, Renate M, Russell, David A, Field, Robert A
Published in Journal of organic chemistry (28.10.2005)
Published in Journal of organic chemistry (28.10.2005)
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Journal Article
Solid-phase synthesis of cyclic RGD-furanoid sugar amino acid peptides as integrin inhibitors
van Well, Renate M., Overkleeft, Herman S., van der Marel, Gijsbert A., Bruss, Dan, Thibault, Gaétan, de Groot, Phillip G., van Boom, Jacques H., Overhand, Mark
Published in Bioorganic & medicinal chemistry letters (10.02.2003)
Published in Bioorganic & medicinal chemistry letters (10.02.2003)
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Journal Article
Discovery of 2-Arylbenzoxazoles as Upregulators of Utrophin Production for the Treatment of Duchenne Muscular Dystrophy
Chancellor, Daniel R, Davies, Kay E, De Moor, Olivier, Dorgan, Colin R, Johnson, Peter D, Lambert, Adam G, Lawrence, Daniel, Lecci, Cristina, Maillol, Carole, Middleton, Penny J, Nugent, Gary, Poignant, Séverine D, Potter, Allyson C, Price, Paul D, Pye, Richard J, Storer, Richard, Tinsley, Jonathon M, van Well, Renate, Vickers, Richard, Vile, Julia, Wilkes, Fraser J, Wilson, Francis X, Wren, Stephen P, Wynne, Graham M
Published in Journal of medicinal chemistry (12.05.2011)
Published in Journal of medicinal chemistry (12.05.2011)
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Journal Article
Synthesis of Fully Substituted Polyhydroxylated Pyrrolizidines via Cope–House Cyclization
Zhang, Wei, Sato, Kasumi, Kato, Atsushi, Jia, Yue-Mei, Hu, Xiang-Guo, Wilson, Francis X, van Well, Renate, Horne, Graeme, Fleet, George W. J, Nash, Robert J, Yu, Chu-Yi
Published in Organic letters (19.08.2011)
Published in Organic letters (19.08.2011)
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Journal Article
Discovery and SAR of 2-arylbenzotriazoles and 2-arylindazoles as potential treatments for Duchenne muscular dystrophy
De Moor, Olivier, Dorgan, Colin R., Johnson, Peter D., Lambert, Adam G., Lecci, Cristina, Maillol, Carole, Nugent, Gary, Poignant, Séverine D., Price, Paul D., Pye, Richard J., Storer, Richard, Tinsley, Jonathon M., Vickers, Richard, Well, Renate van, Wilkes, Fraser J., Wilson, Francis X., Wren, Stephen P., Wynne, Graham M.
Published in Bioorganic & medicinal chemistry letters (15.08.2011)
Published in Bioorganic & medicinal chemistry letters (15.08.2011)
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Journal Article
Reducing tau phosphorylation through inhibition of O-GlcNAc processing
Horne, Graeme, Tinsley, Jon, Czemerys, Louise, Wilkes, Fraser, van Well, Renate, Dorgan, Colin, Fowler, Lindsay, Wilson, Francis, Storer, Richard
Published in Alzheimer's & dementia (01.07.2012)
Published in Alzheimer's & dementia (01.07.2012)
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Journal Article
Conformational Analysis of Furanoid ε-Sugar Amino Acid Containing Cyclic Peptides by NMR Spectroscopy, Molecular Dynamics Simulation, and X-ray Crystallography: Evidence for a Novel Turn Structure
van Well, Renate M, Marinelli, Luciana, Altona, Cornelis, Erkelens, Kees, Siegal, Gregg, van Raaij, Mark, Llamas-Saiz, Antonio L, Kessler, Horst, Novellino, Ettore, Lavecchia, Antonio, van Boom, Jacques H, Overhand, Mark
Published in Journal of the American Chemical Society (10.09.2003)
Published in Journal of the American Chemical Society (10.09.2003)
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Journal Article
A Practical Synthesis of Gramicidin S and Sugar Amino Acid Containing Analogues
Grotenbreg, Gijsbert M, Kronemeijer, Martijn, Timmer, Mattie S. M, El Oualid, Farid, van Well, Renate M, Verdoes, Martijn, Spalburg, Emile, van Hooft, Peter A. V, de Neeling, Albert J, Noort, Daan, van Boom, Jacques H, van der Marel, Gijsbert A, Overkleeft, Herman S, Overhand, Mark
Published in Journal of organic chemistry (12.11.2004)
Published in Journal of organic chemistry (12.11.2004)
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Journal Article
Iodine Promoted Glycosylation with Glycosyl Iodides: α-Glycoside Synthesis
van Well, Renate M., Ravindranathan Kartha, K. P., Field, Robert A.
Published in Journal of carbohydrate chemistry (01.08.2005)
Published in Journal of carbohydrate chemistry (01.08.2005)
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Journal Article
Steviamine, a new class of indolizidine alkaloid [(1R,2S,3R,5R,8aR)-3-hydroxy-meth-yl-5-methyl-octa-hydro-indolizine-1,2-diol hydro-bromide]
Thompson, Amber L, Michalik, Agnieszka, Nash, Robert J, Wilson, Francis X, van Well, Renate, Johnson, Peter, Fleet, George W J, Yu, Chu-Yi, Hu, Xiang-Guo, Cooper, Richard I, Watkin, David J
Published in Acta crystallographica. Section E, Structure reports online (28.10.2009)
Published in Acta crystallographica. Section E, Structure reports online (28.10.2009)
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Journal Article
Synthesis and Structural Analysis of Cyclic Oligomers Consisting of Furanoid and Pyranoid ϵ-Sugar Amino Acids
Well, Renate M. van, Marinelli, Luciana, Erkelens, Kees, Marel, Gijsbert A. van der, Lavecchia, Antonio, Overkleeft, Herman S., Boom, Jacques H. van, Kessler, Horst, Overhand, Mark
Published in European journal of organic chemistry (01.06.2003)
Published in European journal of organic chemistry (01.06.2003)
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Journal Article
Synthesis of Novel Sugar Amino Acids by Curtius Rearrangement
van Well, Renate M., Overkleeft, Herman S., van Boom, Jacques H., Coop, Andrew, Wang, Jia Bei, Wang, Hongyan, van der Marel, Gijsbert A., Overhand, Mark
Published in European journal of organic chemistry (01.05.2003)
Published in European journal of organic chemistry (01.05.2003)
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Journal Article
RNA oligomers at atomic resolution containing 1-methylpseudouridine, an essential building block of mRNA vaccines
Nievergelt, Philipp, Berliat, Florian, McAuley, Katherine E, Dorgan, Colin R, van Well, Renate Maria, Thorn, Andrea, Spingler, Bernhard
Published in ChemMedChem (02.04.2024)
Published in ChemMedChem (02.04.2024)
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Journal Article
Synthesis of Eight Stereoisomers of Pochonicine: Nanomolar Inhibition of β‑N‑Acetylhexosaminidases
Zhu, Jian-She, Nakagawa, Shinpei, Chen, Wei, Adachi, Isao, Jia, Yue-Mei, Hu, Xiang-Guo, Fleet, George W. J, Wilson, Francis X, Nitoda, Teruhiko, Horne, Graeme, van Well, Renate, Kato, Atsushi, Yu, Chu-Yi
Published in Journal of organic chemistry (18.10.2013)
Published in Journal of organic chemistry (18.10.2013)
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Journal Article
P3‐169: Reduction of Tau phosphorylation via novel OGA inhibitors
Horne, Graeme, Chen, Sihong, Well, Renate, Wilkes, Fraser, Wilson, Francis, Tinsley, Jon
Published in Alzheimer's & dementia (01.07.2011)
Published in Alzheimer's & dementia (01.07.2011)
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Journal Article
Reduction of Tau phosphorylation via novel OGA inhibitors
Horne, Graeme, Chen, Sihong, van Well, Renate, Wilkes, Fraser, Wilson, Francis, Tinsley, Jon
Published in Alzheimer's & dementia (01.07.2011)
Published in Alzheimer's & dementia (01.07.2011)
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Journal Article