Selection of human immunodeficiency virus type 1 resistance against the pyranodipyrimidine V-165 points to a multimodal mechanism of action
Hombrouck, A., Hantson, A., van Remoortel, B., Michiels, M., Vercammen, J., Rhodes, D., Tetz, V., Engelborghs, Y., Christ, F., Debyser, Z., Witvrouw, M.
Published in Journal of antimicrobial chemotherapy (01.06.2007)
Published in Journal of antimicrobial chemotherapy (01.06.2007)
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Multiple Drug Resistance to Nucleoside Analogues and Nonnucleoside Reverse Transcriptase Inhibitors in an Efficiently Replicating Human Immunodeficiency Virus Type 1 Patient Strain
Schmit, Jean-Claude, Cogniaux, Jacqueline, Hermans, Philippe, Van Vaeck, Christophe, Sprecher, Susi, Van Remoortel, Barbara, Witvrouw, Myriam, Balzarini, Jan, Desmyter, Jan, De Clercq, Erik, Vandamme, Anne-Mieke
Published in The Journal of infectious diseases (01.11.1996)
Published in The Journal of infectious diseases (01.11.1996)
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Multiple mutations in human immunodeficiency virus-1 integrase confer resistance to the clinical trial drug S-1360
FIKKERT, Valery, HOMBROUCK, Anneleen, VAN REMOORTEL, Barbara, DE MAEYER, Marc, PANNECOUQUE, Christophe, DE CLERCQ, Erik, DEBYSER, Zeger, WITVROUW, Myriam
Published in AIDS (London) (21.10.2004)
Published in AIDS (London) (21.10.2004)
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Development of Resistance against Diketo Derivatives of Human Immunodeficiency Virus Type 1 by Progressive Accumulation of Integrase Mutations
Fikkert, Valery, Van Maele, Bénédicte, Vercammen, Jo, Hantson, Anke, Van Remoortel, Barbara, Michiels, Martine, Gurnari, Cristina, Pannecouque, Christophe, De Maeyer, Marc, Engelborghs, Yves, De Clercq, Erik, Debyser, Zeger, Witvrouw, Myriam
Published in Journal of Virology (01.11.2003)
Published in Journal of Virology (01.11.2003)
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env Chimeric Virus Technology for Evaluating Human Immunodeficiency Virus Susceptibility to Entry Inhibitors
FIKKERT, Valery, CHEREPANOV, Peter, VAN LAETHEM, Kristel, HANTSON, Anke, VAN REMOORTEL, Barbara, PANNECOUQUE, Christophe, DE CLERCQ, Erik, DEBYSER, Zeger, VANDAMME, Anne-Mieke, WITVROUW, Myriam
Published in Antimicrobial Agents and Chemotherapy (01.12.2002)
Published in Antimicrobial Agents and Chemotherapy (01.12.2002)
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Mutations in the non-nucleoside binding-pocket interfere with the multi-nucleoside resistance phenotype
VAN LAETHEM, Kristel, WITVROUW, Myriam, VANDAMME, Anne-Mieke, PANNECOUQUE, Christophe, VAN REMOORTEL, Barbara, SCHMIT, Jean-Claude, ESNOUF, Robert, KLEIM, Jörg-Peter, BALZARINI, Jan, DESMYTER, Jan, DE CLERCQ, Erik
Published in AIDS (London) (30.03.2001)
Published in AIDS (London) (30.03.2001)
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env Chimeric Virus Technology for Evaluating Human Immunodeficiency Virus Susceptibility to Entry Inhibitors
Fikkert, Valery, Cherepanov, Peter, Van Laethem, Kristel, Hantson, Anke, Van Remoortel, Barbara, Pannecouque, Christophe, Clercq, Erik De, Debyser, Zeger, Vandamme, Anne-Mieke, Witvrouw, Myriam
Published in Antimicrobial agents and chemotherapy (01.03.2003)
Published in Antimicrobial agents and chemotherapy (01.03.2003)
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Phenotypic multi-nucleoside resistance linked to the Q151M mutation is enhanced under the selective pressure of acyclic nucleotide analogs but reduced by foscarnet
Van Laethem, K, Witvrouw, M, Pannecouque, C, Van Remoortel, B, Esnouf, R, Balzarini, J, Desmyter, J, De Clercq, E, Vandamme, A-M
Published in AIDS (London) (01.10.2000)
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Published in AIDS (London) (01.10.2000)
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Mutations in Both env and gag genes are required for HIV-1 resistance to the polysulfonic dendrimer SPL2923, as corroborated by chimeric virus technology
Hantson, Anke, Fikkert, Valery, Van Remoortel, Barbara, Pannecouque, Chistophe, Cherepanov, Peter, Matthews, Barry, Holan, George, De Clercq, Erik, Vandamme, Anne-Mieke, Debyser, Zeger, Witvrouw, Myriam
Published in Antiviral chemistry & chemotherapy (2005)
Published in Antiviral chemistry & chemotherapy (2005)
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Cell type-dependent effect of sodium valproate on human immunodeficiency virus type 1 replication in vitro
Witvrouw, M, Schmit, J C, Van Remoortel, B, Daelemans, D, Esté, J A, Vandamme, A M, Desmyter, J, De Clercq, E
Published in AIDS research and human retroviruses (20.01.1997)
Published in AIDS research and human retroviruses (20.01.1997)
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