Mitochondrial and cytoplasmic ROS have opposing effects on lifespan
Schaar, Claire E, Dues, Dylan J, Spielbauer, Katie K, Machiela, Emily, Cooper, Jason F, Senchuk, Megan, Hekimi, Siegfried, Van Raamsdonk, Jeremy M
Published in PLoS genetics (01.02.2015)
Published in PLoS genetics (01.02.2015)
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Overexpression of mitochondrial fission or mitochondrial fusion genes enhances resilience and extends longevity
Traa, Annika, Keil, Allison, AlOkda, Abdelrahman, Jacob‐Tomas, Suleima, Tamez González, Aura A., Zhu, Shusen, Rudich, Zenith, Van Raamsdonk, Jeremy M.
Published in Aging cell (01.10.2024)
Published in Aging cell (01.10.2024)
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Cognitive Dysfunction Precedes Neuropathology and Motor Abnormalities in the YAC128 Mouse Model of Huntington's Disease
Van Raamsdonk, Jeremy M, Pearson, Jacqueline, Slow, Elizabeth J, Hossain, Sazzad M, Leavitt, Blair R, Hayden, Michael R
Published in The Journal of neuroscience (20.04.2005)
Published in The Journal of neuroscience (20.04.2005)
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Activation of DAF-16/FOXO by reactive oxygen species contributes to longevity in long-lived mitochondrial mutants in Caenorhabditis elegans
Senchuk, Megan M, Dues, Dylan J, Schaar, Claire E, Johnson, Benjamin K, Madaj, Zachary B, Bowman, Megan J, Winn, Mary E, Van Raamsdonk, Jeremy M
Published in PLoS genetics (09.03.2018)
Published in PLoS genetics (09.03.2018)
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Naphthalimide-phenothiazine dyads: effect of conformational flexibility and matching of the energy of the charge-transfer state and the localized triplet excited state on the thermally activated delayed fluorescence
Ye, Kaiyue, Cao, Liyuan, van Raamsdonk, Davita M E, Wang, Zhijia, Zhao, Jianzhang, Escudero, Daniel, Jacquemin, Denis
Published in Beilstein journal of organic chemistry (2022)
Published in Beilstein journal of organic chemistry (2022)
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Mitochondrial pyruvate carrier regulates autophagy, inflammation, and neurodegeneration in experimental models of Parkinson's disease
Ghosh, Anamitra, Tyson, Trevor, George, Sonia, Hildebrandt, Erin N, Steiner, Jennifer A, Madaj, Zachary, Schulz, Emily, Machiela, Emily, McDonald, William G, Escobar Galvis, Martha L, Kordower, Jeffrey H, Van Raamsdonk, Jeremy M, Colca, Jerry R, Brundin, Patrik
Published in Science translational medicine (07.12.2016)
Published in Science translational medicine (07.12.2016)
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Mitochondrial unfolded protein response transcription factor ATFS-1 promotes longevity in a long-lived mitochondrial mutant through activation of stress response pathways
Wu, Ziyun, Senchuk, Megan M, Dues, Dylan J, Johnson, Benjamin K, Cooper, Jason F, Lew, Leira, Machiela, Emily, Schaar, Claire E, DeJonge, Heather, Blackwell, T Keith, Van Raamsdonk, Jeremy M
Published in BMC biology (18.12.2018)
Published in BMC biology (18.12.2018)
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Journal Article
Wild‐type huntingtin protects neurons from excitotoxicity
Leavitt, Blair R., Raamsdonk, Jeremy M., Shehadeh, Jacqueline, Fernandes, Herman, Murphy, Zoe, Graham, Rona K., Wellington, Cheryl L., Hayden, Michael R.
Published in Journal of neurochemistry (01.02.2006)
Published in Journal of neurochemistry (01.02.2006)
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Loss of wild-type huntingtin influences motor dysfunction and survival in the YAC128 mouse model of Huntington disease
Van Raamsdonk, Jeremy M., Pearson, Jacqueline, Rogers, Daniel A., Bissada, Nagat, Vogl, A. Wayne, Hayden, Michael R., Leavitt, Blair R.
Published in Human molecular genetics (15.05.2005)
Published in Human molecular genetics (15.05.2005)
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Journal Article
Aging causes decreased resistance to multiple stresses and a failure to activate specific stress response pathways
Dues, Dylan J, Andrews, Emily K, Schaar, Claire E, Bergsma, Alexis L, Senchuk, Megan M, Van Raamsdonk, Jeremy M
Published in Aging (Albany, NY.) (05.04.2016)
Published in Aging (Albany, NY.) (05.04.2016)
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Journal Article
Identification of Novel Therapeutic Targets for Polyglutamine Diseases That Target Mitochondrial Fragmentation
Traa, Annika, Machiela, Emily, Rudich, Paige D, Soo, Sonja K, Senchuk, Megan M, Van Raamsdonk, Jeremy M
Published in International journal of molecular sciences (14.12.2021)
Published in International journal of molecular sciences (14.12.2021)
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The Rab GTPase activating protein TBC-2 regulates endosomal localization of DAF-16 FOXO and lifespan
Meras, Içten, Chotard, Laëtitia, Liontis, Thomas, Ratemi, Zakaria, Wiles, Benjamin, Seo, Jung Hwa, Van Raamsdonk, Jeremy M, Rocheleau, Christian E
Published in PLoS genetics (01.08.2022)
Published in PLoS genetics (01.08.2022)
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