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Pharmacological AMPK activation induces transcriptional responses congruent to exercise in skeletal and cardiac muscle, adipose tissues and liver
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Discovery of novel quinoline carboxylic acid series as DGAT1 inhibitors
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The Impact of Partial and Complete Loss-of-Function Mutations in Endothelial Lipase on High-Density Lipoprotein Levels and Functionality in Humans
Singaraja, Roshni R, Sivapalaratnam, Suthesh, Hovingh, Kees, Dubé, Marie-Pierre, Castro-Perez, José, Collins, Heidi L, Adelman, Steven J, Riwanto, Meliana, Manz, Jasmin, Hubbard, Brian, Tietjen, Ian, Wong, Kenny, Mitnaul, Lyndon J, van Heek, Margaret, Lin, Linus, Roddy, Thomas A, McEwen, Jason, Dallinge-Thie, Geesje, van Vark-van der Zee, Leonie, Verwoert, Germaine, Winther, Michael, van Duijn, Cornelia, Hofman, Albert, Trip, Mieke D, Marais, A David, Asztalos, Bela, Landmesser, Ulf, Sijbrands, Eric, Kastelein, John J, Hayden, Michael R
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Fat Intake Affects Adiposity, Comorbidity Factors, and Energy Metabolism of Sprague-Dawley Rats
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Published in Obesity (Silver Spring, Md.) (01.09.2002)
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Ezetimibe selectively inhibits intestinal cholesterol absorption in rodents in the presence and absence of exocrine pancreatic function
Van Heek, Margaret, Farley, Constance, Compton, Douglas S, Hoos, Lizbeth, Davis, Harry R
Published in British journal of pharmacology (01.09.2001)
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Comparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and its glucuronide, SCH60663
Van Heek, Margaret, Farley, Constance, Compton, Douglas S, Hoos, Lizbeth, Alton, Kevin B, Sybertz, Edmund J, Davis, Harry R
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SAR studies of C2 ethers of 2H-pyrano[2,3-d]pyrimidine-2,4,7(1H,3H)-triones as nicotinic acid receptor (NAR) agonist
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In Vivo Metabolism-Based Discovery of a Potent Cholesterol Absorption Inhibitor, SCH58235, in the Rat and Rhesus Monkey through the Identification of the Active Metabolites of SCH48461
Van Heek, M, France, C F, Compton, D S, McLeod, R L, Yumibe, N P, Alton, K B, Sybertz, E J, Davis, Jr, H R
Published in The Journal of pharmacology and experimental therapeutics (01.10.1997)
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Published in The Journal of pharmacology and experimental therapeutics (01.10.1997)
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VAN HEEK, Margaret, AUSTIN, Theodore M, FARLEY, Constance, COOK, John A, TETZLOFF, Glen G, DAVIS, Harry R
Published in Diabetes (New York, N.Y.) (01.06.2001)
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Ezetimibe potently inhibits cholesterol absorption but does not affect acute hepatic or intestinal cholesterol synthesis in rats
Van Heek, Margaret, Farley, Constance, Compton, Douglas S, Hoos, Lizbeth M, Smith‐Torhan, April, Davis, Harry R
Published in British journal of pharmacology (01.04.2003)
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Kaarsholm, Niels C, Lin, Songnian, Yan, Lin, Kelly, Theresa, van Heek, Margaret, Mu, James, Wu, Margaret, Dai, Ge, Cui, Yan, Zhu, Yonghua, Carballo-Jane, Ester, Reddy, Vijay, Zafian, Peter, Huo, Pei, Shi, Shuai, Antochshuk, Valentyn, Ogawa, Aimie, Liu, Franklin, Souza, Sandra C, Seghezzi, Wolfgang, Duffy, Joseph L, Erion, Mark, Nargund, Ravi P, Kelley, David E
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Cholesteryl Hydroperoxyoctadecadienoate from Oxidized Low Density Lipoprotein Inactivates Platelet-derived Growth Factor
Van Heek, Margaret, Schmitt, David, Toren, Paul, Cathcart, Martha K., DiCorleto, Paul E.
Published in The Journal of biological chemistry (31.07.1998)
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Published in American journal of physiology: endocrinology and metabolism (01.04.2017)
Published in American journal of physiology: endocrinology and metabolism (01.04.2017)
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Bicyclic and tricyclic heterocycle derivatives as histamine H-3 receptor antagonists for the treatment of obesity
Ruiz, Manuel de Lera, Zheng, Junying, Berlin, Michael Y., McCormick, Kevin D., Aslanian, Robert G., West, Robert, Hwa, Joyce, Lachowicz, Jean, van Heek, Margaret
Published in Bioorganic & medicinal chemistry letters (01.11.2013)
Published in Bioorganic & medicinal chemistry letters (01.11.2013)
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