SUCNR1-mediated chemotaxis of macrophages aggravates obesity-induced inflammation and diabetes
van Diepen, Janna A., Robben, Joris H., Hooiveld, Guido J., Carmone, Claudia, Alsady, Mohammad, Boutens, Lily, Bekkenkamp-Grovenstein, Melissa, Hijmans, Anneke, Engelke, Udo F. H., Wevers, Ron A., Netea, Mihai G., Tack, Cees J., Stienstra, Rinke, Deen, Peter M. T.
Published in Diabetologia (01.07.2017)
Published in Diabetologia (01.07.2017)
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Bone marrow transplantation induces changes in the gut microbiota that chronically increase the cytokine response pattern of splenocytes
Katiraei, Saeed, van Diepen, Janna A, Tavares, Luciana P, Hoving, Lisa R, Pronk, Amanda, Verschueren, Ineke, Rensen, Patrick C N, Zwaginga, Jaap Jan, Kostidis, Sarantos, Giera, Martin, Teixera, Mauro, van Dijk, Ko Willems, Netea, Mihai G, Berbée, Jimmy F P, van Harmelen, Vanessa
Published in Scientific reports (27.04.2022)
Published in Scientific reports (27.04.2022)
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Journal Article
Genetic and pharmacological inhibition of vanin-1 activity in animal models of type 2 diabetes
van Diepen, Janna A, Jansen, Patrick A, Ballak, Dov B, Hijmans, Anneke, Rutjes, Floris P J T, Tack, Cees J, Netea, Mihai G, Schalkwijk, Joost, Stienstra, Rinke
Published in Scientific reports (02.03.2016)
Published in Scientific reports (02.03.2016)
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Journal Article
TLR-3 is present in human adipocytes, but its signalling is not required for obesity-induced inflammation in adipose tissue in vivo
Ballak, Dov B, van Asseldonk, Edwin J P, van Diepen, Janna A, Jansen, Henry, Hijmans, Anneke, Joosten, Leo A B, Tack, Cees J, Netea, Mihai G, Stienstra, Rinke
Published in PloS one (13.04.2015)
Published in PloS one (13.04.2015)
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Journal Article
Deletion of hematopoietic Dectin-2 or CARD9 does not protect against atherosclerotic plaque formation in hyperlipidemic mice
Thiem, Kathrin, Hoeke, Geerte, van den Berg, Susan, Hijmans, Anneke, Jacobs, Cor W M, Zhou, Enchen, Mol, Isabel M, Mouktaroudi, Maria, Bussink, Johan, Kanneganti, Thirumala D, Lutgens, Esther, Stienstra, Rinke, Tack, Cees J, Netea, Mihai G, Rensen, Patrick C N, Berbée, Jimmy F P, van Diepen, Janna A
Published in Scientific reports (13.03.2019)
Published in Scientific reports (13.03.2019)
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Journal Article
Activation of Proteinase 3 Contributes to Nonalcoholic Fatty Liver Disease and Insulin Resistance
Toonen, Erik J M, Mirea, Andreea-Manuela, Tack, Cees J, Stienstra, Rinke, Ballak, Dov B, van Diepen, Janna A, Hijmans, Anneke, Chavakis, Triantafyllos, Dokter, Wim H, Pham, Christine T N, Netea, Mihai G, Dinarello, Charles A, Joosten, Leo A B
Published in Molecular medicine (Cambridge, Mass.) (01.01.2016)
Published in Molecular medicine (Cambridge, Mass.) (01.01.2016)
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Journal Article
IL-1 family members in the pathogenesis and treatment of metabolic disease: Focus on adipose tissue inflammation and insulin resistance
Ballak, Dov B., Stienstra, Rinke, Tack, Cees J., Dinarello, Charles A., van Diepen, Janna A.
Published in Cytokine (Philadelphia, Pa.) (01.10.2015)
Published in Cytokine (Philadelphia, Pa.) (01.10.2015)
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Journal Article
IL-37 Expression Reduces Lean Body Mass in Mice by Reducing Food Intake
Kuipers, Eline N, van Dam, Andrea D, Ballak, Dov B, de Wit, Ellemiek A, Dinarello, Charles A, Stienstra, Rinke, van Diepen, Janna A, Rensen, Patrick C N, Boon, Mariëtte R
Published in International journal of molecular sciences (02.08.2018)
Published in International journal of molecular sciences (02.08.2018)
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Journal Article
The Effects of Selective Hematopoietic Expression of Human IL-37 on Systemic Inflammation and Atherosclerosis in LDLr-Deficient Mice
Hoeke, Geerte, Khedoe, P Padmini S J, van Diepen, Janna A, Pike-Overzet, Karin, van de Ven, Britt, Vazirpanah, Nadia, Mol, Isabel, Hiemstra, Pieter S, Staal, Frank J T, Stienstra, Rinke, Netea, Mihai G, Dinarello, Charles A, Rensen, Patrick C N, Berbée, Jimmy F P
Published in International journal of molecular sciences (09.08.2017)
Published in International journal of molecular sciences (09.08.2017)
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Journal Article
MAP3K8 (TPL2/COT) affects obesity-induced adipose tissue inflammation without systemic effects in humans and in mice
Ballak, Dov B, van Essen, Peter, van Diepen, Janna A, Jansen, Henry, Hijmans, Anneke, Matsuguchi, Tetsuya, Sparrer, Helmut, Tack, Cees J, Netea, Mihai G, Joosten, Leo A B, Stienstra, Rinke
Published in PloS one (24.02.2014)
Published in PloS one (24.02.2014)
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Journal Article
Interleukin-37 treatment of mice with metabolic syndrome improves insulin sensitivity and reduces pro-inflammatory cytokine production in adipose tissue
Ballak, Dov B., Li, Suzhao, Cavalli, Giulio, Stahl, Jonathan L., Tengesdal, Isak W., van Diepen, Janna A., Klück, Viola, Swartzwelter, Benjamin, Azam, Tania, Tack, Cees J., Stienstra, Rinke, Mandrup-Poulsen, Thomas, Seals, Douglas R., Dinarello, Charles A.
Published in The Journal of biological chemistry (14.09.2018)
Published in The Journal of biological chemistry (14.09.2018)
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Journal Article
Inflammasome is a central player in the induction of obesity and insulin resistance
Stienstra, Rinke, van Diepen, Janna A, Tack, Cees J, Zaki, Md. Hasan, van de Veerdonk, Frank L, Perera, Deshani, Neale, Geoffrey A, Hooiveld, Guido J, Hijmans, Anneke, Vroegrijk, Irene, van den Berg, Sjoerd, Romijn, Johannes, Rensen, Patrick C. N, Joosten, Leo A. B, Netea, Mihai G, Kanneganti, Thirumala-Devi
Published in Proceedings of the National Academy of Sciences - PNAS (13.09.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (13.09.2011)
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Journal Article
The Inflammasome-Mediated Caspase-1 Activation Controls Adipocyte Differentiation and Insulin Sensitivity
Stienstra, Rinke, Joosten, Leo A.B., Koenen, Tim, van Tits, Berry, van Diepen, Janna A., van den Berg, Sjoerd A.A., Rensen, Patrick C.N., Voshol, Peter J., Fantuzzi, Giamilla, Hijmans, Anneke, Kersten, Sander, Müller, Michael, van den Berg, Wim B., van Rooijen, Nico, Wabitsch, Martin, Kullberg, Bart-Jan, van der Meer, Jos W.M., Kanneganti, Thirumala, Tack, Cees J., Netea, Mihai G.
Published in Cell metabolism (01.12.2010)
Published in Cell metabolism (01.12.2010)
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Journal Article
IL-37 protects against obesity-induced inflammation and insulin resistance
Ballak, Dov B, van Diepen, Janna A, Moschen, Alexander R, Jansen, Henry J, Hijmans, Anneke, Groenhof, Gert-Jan, Leenders, Floris, Bufler, Philip, Boekschoten, Mark V, Müller, Michael, Kersten, Sander, Li, Suzhao, Kim, SooHyun, Eini, Hadar, Lewis, Eli C, Joosten, Leo A B, Tilg, Herbert, Netea, Mihai G, Tack, Cees J, Dinarello, Charles A, Stienstra, Rinke
Published in Nature communications (03.09.2014)
Published in Nature communications (03.09.2014)
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Journal Article
META060 protects against diet-induced obesity and insulin resistance in a high-fat–diet fed mouse
Vroegrijk, Irene O.C.M., M.Sc, van Diepen, Janna A., M.Sc, van den Berg, Sjoerd A.A., Ph.D, Romijn, Johannes A., M.D., Ph.D, Havekes, Louis M., Ph.D, van Dijk, Ko Willems, Ph.D, Darland, Gary, Ph.D, Konda, Veera, Ph.D, Tripp, Matthew L., Ph.D, Bland, Jeffrey S., Ph.D, Voshol, Peter J., Ph.D
Published in Nutrition (Burbank, Los Angeles County, Calif.) (2013)
Published in Nutrition (Burbank, Los Angeles County, Calif.) (2013)
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Journal Article
Allosteric Regulation of Glycogen Synthase Controls Glycogen Synthesis in Muscle
Bouskila, Michale, Hunter, Roger W., Ibrahim, Adel F.M., Delattre, Lucie, Peggie, Mark, van Diepen, Janna A., Voshol, Peter J., Jensen, Jørgen, Sakamoto, Kei
Published in Cell metabolism (03.11.2010)
Published in Cell metabolism (03.11.2010)
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Journal Article
Milk fat globule membrane attenuates high fat diet-induced neuropathological changes in obese Ldlr-/-.Leiden mice
Arnoldussen, Ilse A C, Morrison, Martine C, Wiesmann, Maximilian, van Diepen, Janna A, Worms, Nicole, Voskuilen, Marijke, Verweij, Vivienne, Geenen, Bram, Gualdo, Natàlia Pujol, van der Logt, Lonneke, Gross, Gabriele, Kleemann, Robert, Kiliaan, Amanda J
Published in International Journal of Obesity (01.02.2022)
Published in International Journal of Obesity (01.02.2022)
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Journal Article
Evaluation of chitotriosidase as a biomarker for adipose tissue inflammation in overweight individuals and type 2 diabetic patients
Tans, Roel, van Diepen, Janna A, Bijlsma, Sabina, Verschuren, Lars, Suppers, Anouk, Stienstra, Rinke, Wevers, Ron A, Tack, Cees J, Gloerich, Jolein, van Gool, Alain J
Published in International Journal of Obesity (01.09.2019)
Published in International Journal of Obesity (01.09.2019)
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