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Published in PloS one (28.02.2013)
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Hyperlipidemia in APOE2 transgenic mice is ameliorated by a truncated apoE variant lacking the C-terminal domain
Gerritsen, Gery, Kypreos, Kyriakos E, van der Zee, André, Teusink, Bas, Zannis, Vassilis I, Havekes, Louis M, van Dijk, Ko Willems
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Published in Journal of lipid research (01.02.2003)
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Both Lipolysis and Hepatic Uptake of VLDL Are Impaired in Transgenic Mice Coexpressing Human Apolipoprotein E3Leiden and Human Apolipoprotein C1
Jong, Miek C, Dahlmans, Vivian E.H, van Gorp, Patrick J.J, Breuer, Marco L, Mol, Marc J.T.M, van der Zee, Andre, Frants, Rune R, Hofker, Marten H, Havekes, Louis M
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Published in Arteriosclerosis, thrombosis, and vascular biology (01.08.1996)
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Adenovirus mediated overexpression of human phospholipid transfer protein alters plasma HDL levels in mice
Ehnholm, S, van Dijk, K W, van 't Hof, B, van der Zee, A, Olkkonen, V M, Jauhiainen, M, Hofker, M, Havekes, L, Ehnholm, C
Published in Journal of lipid research (01.06.1998)
Published in Journal of lipid research (01.06.1998)
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In LDL receptor-deficient mice, catabolism of remnant lipoproteins requires a high level of apoE but is inhibited by excess apoE
van Dijk, K W, van Vlijmen, B J, van't Hof, H B, van der Zee, A, Santamarina-Fojo, S, van Berkel, T J, Havekes, L M, Hofker, M H
Published in Journal of lipid research (01.02.1999)
Published in Journal of lipid research (01.02.1999)
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Reversal of Hypercholesterolemia in Apolipoprotein E2 and Apolipoprotein E3-Leiden Transgenic Mice by Adenovirus-Mediated Gene Transfer of the VLDL Receptor
van Dijk, Ko Willems, van Vlijmen, Bart J.M, van der Zee, Andre, van't Hof, Belinda, van der Boom, Hans, Kobayashi, Kunihisa, Chan, Lawrence, Havekes, Louis M, Hofker, Marten H
Published in Arteriosclerosis, thrombosis, and vascular biology (01.01.1998)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.01.1998)
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Effective generation of very low density lipoprotein receptor transgenic mice by overlapping genomic DNA fragments: high testis expression and disturbed spermatogenesis
TACKEN, Paul J, VAN DER ZEE, Andre, BEUMER, Tim L, FLORIJN, Ralph J, GIJPELS, Marion J. J, HAVEKES, Louis M, FRANTS, Rune R, VAN DIJK, Ko Willems, HOFKER, Marten H
Published in Transgenic research (01.06.2001)
Published in Transgenic research (01.06.2001)
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Domains of apolipoprotein E contributing to triglyceride and cholesterol homeostasis in vivo. Carboxyl-terminal region 203-299 promotes hepatic very low density lipoprotein-triglyceride secretion
Kypreos, K E, van Dijk, K W, van Der Zee, A, Havekes, L M, Zannis, V I
Published in The Journal of biological chemistry (08.06.2001)
Published in The Journal of biological chemistry (08.06.2001)
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Dynamic changes in mouse lipoproteins induced by transiently expressed human phospholipid transfer protein (PLTP): importance of PLTP in preβ-HDL generation
Jaari, Sonja, van Dijk, Ko Willems, Olkkonen, Vesa M., van der Zee, Andre, Metso, Jari, Havekes, Louis, Jauhiainen, Matti, Ehnholm, Christian
Published in Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology (01.04.2001)
Published in Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology (01.04.2001)
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Apolipoprotein E2 (Lys146→Gln) Causes Hypertriglyceridemia due to an Apolipoprotein E Variant–Specific Inhibition of Lipolysis of Very Low Density Lipoproteins–Triglycerides
de Beer, Femke, van Dijk, Ko Willems, Jong, Miek C, van Vark, Leonie C, van der Zee, Andre, Hofker, Marten H, Fallaux, Frits J, Hoeben, Rob C, Smelt, Augustinus H. M, Havekes, Louis M
Published in Arteriosclerosis, thrombosis, and vascular biology (01.07.2000)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.07.2000)
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Hyperlipidemia of ApoE2(Arg158-Cys) and ApoE3-Leiden Transgenic Mice Is Modulated Predominantly by LDL Receptor Expression
van Dijk, Ko Willems, van Vlijmen, Bart J. M, de Winther, Menno P. J, Hof, Belinda van ’t, van der Zee, Andre, van der Boom, Hans, Havekes, Louis M, Hofker, Marten H
Published in Arteriosclerosis, thrombosis, and vascular biology (01.12.1999)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.12.1999)
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4.P.316 Generation of very low density lipoprotein receptor overexpressing mice
Tacken, Paul J., van der Zee, Andre, van Dijk, Ko Willems, Frants, Rune R., Havekes, Louis M., Hofker, Marten H.
Published in Atherosclerosis (01.10.1997)
Published in Atherosclerosis (01.10.1997)
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Adenovirus mediated overexpression of human phospholipid transfer protein alters plasma HDL levels in mice1
Sonja Ehnholm, Ko Willems van Dijk, Belinda van't Hof, Andre van der Zee, Vesa M. Olkkonen, Matti Jauhiainen, Marten Hofker, Louis Havekes, Christian Ehnholm
Published in Journal of lipid research (01.06.1998)
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Published in Journal of lipid research (01.06.1998)
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73 Effect of adenovirus mediated overexpression of human phospholipid transfer protein (PLTP) on the plasma lipoprotein profile in different strains of transgenic mice
Ehnholm, Sonja, van Dijk, Ko Willems, van der Zee, Andre, van 't Hof, Belinda, Hofker, Marten H., Havekes, Louis M., Jauhiainen, M., Olkkonen, V., Ehnholm, C.
Published in Atherosclerosis (01.05.1997)
Published in Atherosclerosis (01.05.1997)
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Apolipoprotein CI causes hypertriglyceridemia independent of the very-low-density lipoprotein receptor and apolipoprotein CIII in mice
van der Hoogt, Caroline C., Berbée, Jimmy F.P., Espirito Santo, Sonia M.S., Gerritsen, Gery, Krom, Yvonne D., van der Zee, André, Havekes, Louis M., van Dijk, Ko Willems, Rensen, Patrick C.N.
Published in Biochimica et biophysica acta (01.02.2006)
Published in Biochimica et biophysica acta (01.02.2006)
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Modulation of very low density lipoprotein production and clearance contributes to age- and gender- dependent hyperlipoproteinemia in apolipoprotein E3-Leiden transgenic mice
van Vlijmen, B J, van 't Hof, H B, Mol, M J, van der Boom, H, van der Zee, A, Frants, R R, Hofker, M H, Havekes, L M
Published in The Journal of clinical investigation (01.03.1996)
Published in The Journal of clinical investigation (01.03.1996)
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In the Absence of Endogenous Mouse Apolipoprotein E, Apolipoprotein E2(Arg-158 → Cys) Transgenic Mice Develop More Severe Hyperlipoproteinemia than Apolipoprotein E3-Leiden Transgenic Mice
van Vlijmen, Bart J.M., van Dijk, Ko Willems, van't Hof, H. Belinda, van Gorp, Patrick J.J., van der Zee, André, van der Boom, Hans, Breuer, Marco L., Hofker, Marten H., Havekes, Louis M.
Published in The Journal of biological chemistry (29.11.1996)
Published in The Journal of biological chemistry (29.11.1996)
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Inactivation of Apoe and Apoc1 by two consecutive rounds of gene targeting: effects on mRNA expression levels of gene cluster members
van Ree, J H, van den Broek, W J, van der Zee, A, Dahlmans, V E, Wieringa, B, Frants, R R, Havekes, L M, Hofker, M H
Published in Human molecular genetics (01.08.1995)
Published in Human molecular genetics (01.08.1995)
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