Structure- and function-based design of Plasmodium-selective proteasome inhibitors
Li, Hao, O’Donoghue, Anthony J., van der Linden, Wouter A., Xie, Stanley C., Yoo, Euna, Foe, Ian T., Tilley, Leann, Craik, Charles S., da Fonseca, Paula C. A., Bogyo, Matthew
Published in Nature (London) (11.02.2016)
Published in Nature (London) (11.02.2016)
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Journal Article
Global Analysis of Palmitoylated Proteins in Toxoplasma gondii
Foe, Ian T., Child, Matthew A., Majmudar, Jaimeen D., Krishnamurthy, Shruthi, van der Linden, Wouter A., Ward, Gary E., Martin, Brent R., Bogyo, Matthew
Published in Cell host & microbe (14.10.2015)
Published in Cell host & microbe (14.10.2015)
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Journal Article
Proteasome Inhibitors: An Expanding Army Attacking a Unique Target
Kisselev, Alexei F., van der Linden, Wouter A., Overkleeft, Herman S.
Published in Chemistry & biology (27.01.2012)
Published in Chemistry & biology (27.01.2012)
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Journal Article
Non-invasive Imaging of Idiopathic Pulmonary Fibrosis Using Cathepsin Protease Probes
Withana, Nimali P., Ma, Xiaowei, McGuire, Helen M., Verdoes, Martijn, van der Linden, Wouter A., Ofori, Leslie O., Zhang, Ruiping, Li, Hao, Sanman, Laura E., Wei, Ke, Yao, Shaobo, Wu, Peilin, Li, Fang, Huang, Hui, Xu, Zuojun, Wolters, Paul J., Rosen, Glenn D., Collard, Harold R., Zhu, Zhaohui, Cheng, Zhen, Bogyo, Matthew
Published in Scientific reports (22.01.2016)
Published in Scientific reports (22.01.2016)
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Journal Article
Development of an activity-based probe for acyl-protein thioesterases
Garland, Megan, Schulze, Christopher J, Foe, Ian T, van der Linden, Wouter A, Child, Matthew A, Bogyo, Matthew
Published in PloS one (24.01.2018)
Published in PloS one (24.01.2018)
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Journal Article
Bioorthogonal Chemistry: Applications in Activity-Based Protein Profiling
Willems, Lianne I, van der Linden, Wouter A, Li, Nan, Li, Kah-Yee, Liu, Nora, Hoogendoorn, Sascha, van der Marel, Gijs A, Florea, Bogdan I, Overkleeft, Herman S
Published in Accounts of chemical research (20.09.2011)
Published in Accounts of chemical research (20.09.2011)
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Journal Article
The novel β2-selective proteasome inhibitor LU-102 synergizes with bortezomib and carfilzomib to overcome proteasome inhibitor resistance of myeloma cells
Kraus, Marianne, Bader, Juergen, Geurink, Paul P, Weyburne, Emily S, Mirabella, Anne C, Silzle, Tobias, Shabaneh, Tamer B, van der Linden, Wouter A, de Bruin, Gerjan, Haile, Sarah R, van Rooden, Eva, Appenzeller, Christina, Li, Nan, Kisselev, Alexei F, Overkleeft, Herman, Driessen, Christoph
Published in Haematologica (Roma) (01.10.2015)
Published in Haematologica (Roma) (01.10.2015)
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Journal Article
Cysteine cathepsin activity suppresses osteoclastogenesis of myeloid-derived suppressor cells in breast cancer
Edgington-Mitchell, Laura E, Rautela, Jai, Duivenvoorden, Hendrika M, Jayatilleke, Krishnath M, van der Linden, Wouter A, Verdoes, Martijn, Bogyo, Matthew, Parker, Belinda S
Published in Oncotarget (29.09.2015)
Published in Oncotarget (29.09.2015)
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Journal Article
Legumain is activated in macrophages during pancreatitis
Edgington-Mitchell, Laura E, Wartmann, Thomas, Fleming, Alicia K, Gocheva, Vasilena, van der Linden, Wouter A, Withana, Nimali P, Verdoes, Martijn, Aurelio, Luigi, Edgington-Mitchell, Daniel, Lieu, TinaMarie, Parker, Belinda S, Graham, Bim, Reinheckel, Thomas, Furness, John B, Joyce, Johanna A, Storz, Peter, Halangk, Walter, Bogyo, Matthew, Bunnett, Nigel W
Published in American journal of physiology: Gastrointestinal and liver physiology (01.09.2016)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.09.2016)
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Journal Article
Deletion of the rodent malaria ortholog for falcipain-1 highlights differences between hepatic and blood stage merozoites
Hopp, Christine S, Bennett, Brandy L, Mishra, Satish, Lehmann, Christine, Hanson, Kirsten K, Lin, Jing-Wen, Rousseau, Kimberly, Carvalho, Filomena A, van der Linden, Wouter A, Santos, Nuno C, Bogyo, Matthew, Khan, Shahid M, Heussler, Volker, Sinnis, Photini
Published in PLoS pathogens (01.09.2017)
Published in PLoS pathogens (01.09.2017)
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Journal Article
Toxoplasma DJ-1 Regulates Organelle Secretion by a Direct Interaction with Calcium-Dependent Protein Kinase 1
Child, Matthew A, Garland, Megan, Foe, Ian, Madzelan, Peter, Treeck, Moritz, van der Linden, Wouter A, Oresic Bender, Kristina, Weerapana, Eranthie, Wilson, Mark A, Boothroyd, John C, Reese, Michael L, Bogyo, Matthew
Published in mBio (28.02.2017)
Published in mBio (28.02.2017)
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Journal Article
Improved Quenched Fluorescent Probe for Imaging of Cysteine Cathepsin Activity
Verdoes, Martijn, Oresic Bender, Kristina, Segal, Ehud, van der Linden, Wouter A, Syed, Salahuddin, Withana, Nimali P, Sanman, Laura E, Bogyo, Matthew
Published in Journal of the American Chemical Society (02.10.2013)
Published in Journal of the American Chemical Society (02.10.2013)
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Journal Article
Two-step bioorthogonal activity-based proteasome profiling using copper-free click reagents: A comparative study
van der Linden, Wouter A., Li, Nan, Hoogendoorn, Sascha, Ruben, Mark, Verdoes, Martijn, Guo, Jun, Boons, Geert-Jan, van der Marel, Gijsbert A., Florea, Bogdan I., Overkleeft, Herman S.
Published in Bioorganic & medicinal chemistry (15.01.2012)
Published in Bioorganic & medicinal chemistry (15.01.2012)
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Journal Article
Detection of Intestinal Cancer by Local, Topical Application of a Quenched Fluorescence Probe for Cysteine Cathepsins
Segal, Ehud, Prestwood, Tyler R., van der Linden, Wouter A., Carmi, Yaron, Bhattacharya, Nupur, Withana, Nimali, Verdoes, Martijn, Habtezion, Aida, Engleman, Edgar G., Bogyo, Matthew
Published in Chemistry & biology (22.01.2015)
Published in Chemistry & biology (22.01.2015)
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Journal Article
Design of a Highly Selective Quenched Activity-Based Probe and Its Application in Dual Color Imaging Studies of Cathepsin S Activity Localization
Oresic Bender, Kristina, Ofori, Leslie, van der Linden, Wouter A, Mock, Elliot D, Datta, Gopal K, Chowdhury, Somenath, Li, Hao, Segal, Ehud, Sanchez Lopez, Mateo, Ellman, Jonathan A, Figdor, Carl G, Bogyo, Matthew, Verdoes, Martijn
Published in Journal of the American Chemical Society (15.04.2015)
Published in Journal of the American Chemical Society (15.04.2015)
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Journal Article
Relative quantification of proteasome activity by activity-based protein profiling and LC-MS/MS
Li, Nan, Kuo, Chi-Lin, Paniagua, Guillem, van den Elst, Hans, Verdoes, Martijn, Willems, Lianne I, van der Linden, Wouter A, Ruben, Mark, van Genderen, Eric, Gubbens, Jacob, van Wezel, Gilles P, Overkleeft, Herman S, Florea, Bogdan I
Published in Nature protocols (01.06.2013)
Published in Nature protocols (01.06.2013)
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Journal Article
Incorporation of Non-natural Amino Acids Improves Cell Permeability and Potency of Specific Inhibitors of Proteasome Trypsin-like Sites
Geurink, Paul P, van der Linden, Wouter A, Mirabella, Anne C, Gallastegui, Nerea, de Bruin, Gerjan, Blom, Annet E. M, Voges, Mathias J, Mock, Elliot D, Florea, Bogdan I, van der Marel, Gijs A, Driessen, Christoph, van der Stelt, Mario, Groll, Michael, Overkleeft, Herman S, Kisselev, Alexei F
Published in Journal of medicinal chemistry (14.02.2013)
Published in Journal of medicinal chemistry (14.02.2013)
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Journal Article
Assessing Subunit Dependency of the Plasmodium Proteasome Using Small Molecule Inhibitors and Active Site Probes
Li, Hao, van der Linden, Wouter A, Verdoes, Martijn, Florea, Bogdan I, McAllister, Fiona E, Govindaswamy, Kavitha, Elias, Joshua E, Bhanot, Purnima, Overkleeft, Herman S, Bogyo, Matthew
Published in ACS chemical biology (15.08.2014)
Published in ACS chemical biology (15.08.2014)
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