A trispecific killer engager molecule against CLEC12A effectively induces NK-cell mediated killing of AML cells
Arvindam, Upasana Sunil, van Hauten, Paulien M. M., Schirm, Dawn, Schaap, Nicolaas, Hobo, Willemijn, Blazar, Bruce R., Vallera, Daniel A., Dolstra, Harry, Felices, Martin, Miller, Jeffrey S.
Published in Leukemia (01.06.2021)
Published in Leukemia (01.06.2021)
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CD16xCD33 bispecific killer cell engager (BiKE) activates NK cells against primary MDS and MDSC CD33+ targets
Gleason, Michelle K., Ross, Julie A., Warlick, Erica D., Lund, Troy C., Verneris, Michael R., Wiernik, Andres, Spellman, Stephen, Haagenson, Michael D., Lenvik, Alexander J., Litzow, Mark R., Epling-Burnette, Pearlie K., Blazar, Bruce R., Weiner, Louis M., Weisdorf, Daniel J., Vallera, Daniel A., Miller, Jeffrey S.
Published in Blood (08.05.2014)
Published in Blood (08.05.2014)
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Phase I study of a bispecific ligand-directed toxin targeting CD22 and CD19 (DT2219) for refractory B-cell malignancies
Bachanova, Veronika, Frankel, Arthur E, Cao, Qing, Lewis, Dixie, Grzywacz, Bartosz, Verneris, Michael R, Ustun, Celalettin, Lazaryan, Aleksandr, McClune, Brian, Warlick, Erica D, Kantarjian, Hagop, Weisdorf, Daniel J, Miller, Jeffrey S, Vallera, Daniel A
Published in Clinical cancer research (15.03.2015)
Published in Clinical cancer research (15.03.2015)
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Journal Article
A tri-specific killer engager against mesothelin targets NK cells towards lung cancer
Kennedy, Philippa R, Vallera, Daniel A, Ettestad, Brianna, Hallstrom, Caroline, Kodal, Behiye, Todhunter, Deborah A, Bendzick, Laura, Hinderlie, Peter, Walker, Joshua T, Pulkrabek, Brittany, Pastan, Ira, Kratzke, Robert A, Fujioka, Naomi, Miller, Jeffrey S, Felices, Martin
Published in Frontiers in immunology (22.02.2023)
Published in Frontiers in immunology (22.02.2023)
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Journal Article
161533 TriKE stimulates NK-cell function to overcome myeloid-derived suppressor cells in MDS
Sarhan, Dhifaf, Brandt, Ludwig, Felices, Martin, Guldevall, Karolin, Lenvik, Todd, Hinderlie, Peter, Curtsinger, Julie, Warlick, Erica, Spellman, Stephen R., Blazar, Bruce R., Weisdorf, Daniel J., Cooley, Sarah, Vallera, Daniel A., Önfelt, Björn, Miller, Jeffrey S.
Published in Blood advances (26.06.2018)
Published in Blood advances (26.06.2018)
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Journal Article
Development of a Deimmunized Bispecific Immunotoxin dDT2219 against B-Cell Malignancies
Schmohl, Joerg U, Todhunter, Deborah, Taras, Elizabeth, Bachanova, Veronika, Vallera, Daniel A
Published in Toxins (06.01.2018)
Published in Toxins (06.01.2018)
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Journal Article
Toxicity Profile of eBAT, a Bispecific Ligand-Targeted Toxin Directed to EGFR and uPAR, in Mice and a Clinical Dog Model
Dicovitsky, Rose H, Schappa, Jill T, Schulte, Ashley J, Lang, Haeree P, Kuerbitz, Ellen, Roberts, Sarah, DePauw, Taylor A, Lewellen, Mitzi, Winter, Amber L, Stuebner, Kathy, Buettner, Michelle, Reid, Kelly, Bergsrud, Kelly, Pracht, Sara, Chehadeh, Andrea, Feiock, Caitlin, O'Sullivan, M Gerard, Carlson, Tim, Armstrong, Alexandra R, Meritet, Danielle, Henson, Michael S, Weigel, Brenda J, Modiano, Jaime F, Borgatti, Antonella, Vallera, Daniel A
Published in Toxins (01.09.2024)
Published in Toxins (01.09.2024)
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Chemically Self-Assembled Antibody Nanorings (CSANs): Design and Characterization of an Anti-CD3 IgM Biomimetic
Li, Qing, So, Christopher R, Fegan, Adrian, Cody, Vivian, Sarikaya, Mehmet, Vallera, Daniel A, Wagner, Carston R
Published in Journal of the American Chemical Society (08.12.2010)
Published in Journal of the American Chemical Society (08.12.2010)
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Journal Article
Immunotherapeutic Development of a Tri-Specific NK Cell Engager Recognizing BCMA
Oh, Felix, Felices, Martin, Kodal, Behiye, Miller, Jeffrey S., Vallera, Daniel A.
Published in Immuno (01.06.2023)
Published in Immuno (01.06.2023)
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Evaluation of 18-F-fluoro-2-deoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) as a staging and monitoring tool for dogs with stage-2 splenic hemangiosarcoma - A pilot study
Borgatti, Antonella, Winter, Amber L, Stuebner, Kathleen, Scott, Ruth, Ober, Christopher P, Anderson, Kari L, Feeney, Daniel A, Vallera, Daniel A, Koopmeiners, Joseph S, Modiano, Jaime F, Froelich, Jerry
Published in PloS one (01.02.2017)
Published in PloS one (01.02.2017)
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Hemangiosarcoma and its cancer stem cell subpopulation are effectively killed by a toxin targeted through epidermal growth factor and urokinase receptors
Schappa, Jill T., Frantz, Aric M., Gorden, Brandi H., Dickerson, Erin B., Vallera, Daniel A., Modiano, Jaime F.
Published in International journal of cancer (15.10.2013)
Published in International journal of cancer (15.10.2013)
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Journal Article
Trispecific killer engager CD16xIL15xCD33 potently induces NK cell activation and cytotoxicity against neoplastic mast cells
Don Yun, Hyun, Felices, Martin, Vallera, Daniel A., Hinderlie, Peter, Cooley, Sarah, Arock, Michel, Gotlib, Jason, Ustun, Celalettin, Miller, Jeffrey S.
Published in Blood advances (10.07.2018)
Published in Blood advances (10.07.2018)
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Journal Article
A bispecific EpCAM/CD133-targeted toxin is effective against carcinoma
Waldron, Nate N., Barsky, Sanford H., Dougherty, Phillip R., Vallera, Daniel A.
Published in Targeted oncology (01.09.2014)
Published in Targeted oncology (01.09.2014)
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Journal Article
A Novel Reduced Immunogenicity Bispecific Targeted Toxin Simultaneously Recognizing Human Epidermal Growth Factor and Interleukin-4 Receptors in a Mouse Model of Metastatic Breast Carcinoma
Oh, Seunguk, Stish, Brad J, Sachdev, Deepali, Chen, Hua, Dudek, Arkadiusz Z, Vallera, Daniel A
Published in Clinical cancer research (01.10.2009)
Published in Clinical cancer research (01.10.2009)
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