Honokiol inhibits signal transducer and activator of transcription-3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine phosphatase SHP-1
Rajendran, Peramaiyan, Li, Feng, Shanmugam, Muthu K., Vali, Shireen, Abbasi, Taher, Kapoor, Shweta, Ahn, Kwang Seok, Kumar, Alan Prem, Sethi, Gautam
Published in Journal of cellular physiology (01.05.2012)
Published in Journal of cellular physiology (01.05.2012)
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Suppression of Signal Transducer and Activator of Transcription 3 Activation by Butein Inhibits Growth of Human Hepatocellular Carcinoma In Vivo
RAJENDRAN, Peramaiyan, ONG, Tina H, HUI, Kam M, SETHI, Gautam, LUXI CHEN, FENG LI, SHANMUGAM, Muthu K, VALI, Shireen, ABBASI, Taher, KAPOOR, Shweta, SHARMA, Ashish, PREM KUMAR, Alan
Published in Clinical cancer research (15.03.2011)
Published in Clinical cancer research (15.03.2011)
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Journal Article
Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4
Manu, Kanjoormana Aryan, Shanmugam, Muthu K, Rajendran, Peramaiyan, Li, Feng, Ramachandran, Lalitha, Hay, Hui Sin, Kannaiyan, Radhamani, Swamy, Shivananju Nanjunda, Vali, Shireen, Kapoor, Shweta, Ramesh, Bhargavi, Bist, Pradeep, Koay, Evelyn S, Lim, Lina H K, Ahn, Kwang Seok, Kumar, Alan Prem, Sethi, Gautam
Published in Molecular cancer (01.09.2011)
Published in Molecular cancer (01.09.2011)
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Novel anti-glioblastoma agents and therapeutic combinations identified from a collection of FDA approved drugs
Jiang, Pengfei, Mukthavaram, Rajesh, Mukthavavam, Rajesh, Chao, Ying, Bharati, Ila Sri, Fogal, Valentina, Pastorino, Sandra, Cong, Xiuli, Nomura, Natsuko, Gallagher, Matt, Abbasi, Taher, Vali, Shireen, Pingle, Sandeep C, Makale, Milan, Kesari, Santosh
Published in Journal of translational medicine (17.01.2014)
Published in Journal of translational medicine (17.01.2014)
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Dual inhibition of akt/mammalian target of rapamycin pathway by nanoparticle albumin-bound-rapamycin and perifosine induces antitumor activity in multiple myeloma
Cirstea, Diana, Hideshima, Teru, Rodig, Scott, Santo, Loredana, Pozzi, Samantha, Vallet, Sonia, Ikeda, Hiroshi, Perrone, Giulia, Gorgun, Gullu, Patel, Kishan, Desai, Neil, Sportelli, Peter, Kapoor, Shweta, Vali, Shireen, Mukherjee, Siddhartha, Munshi, Nikhil C, Anderson, Kenneth C, Raje, Noopur
Published in Molecular cancer therapeutics (01.04.2010)
Published in Molecular cancer therapeutics (01.04.2010)
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Genomics of NSCLC patients both affirm PD-L1 expression and predict their clinical responses to anti-PD-1 immunotherapy
Brogden, Kim A, Parashar, Deepak, Hallier, Andrea R, Braun, Terry, Qian, Fang, Rizvi, Naiyer A, Bossler, Aaron D, Milhem, Mohammed M, Chan, Timothy A, Abbasi, Taher, Vali, Shireen
Published in BMC cancer (27.02.2018)
Published in BMC cancer (27.02.2018)
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Amplification and Demultiplexing in Insulin-regulated Akt Protein Kinase Pathway in Adipocytes
Tan, Shi-Xiong, Ng, Yvonne, Meoli, Christopher C., Kumar, Ansu, Khoo, Poh-Sim, Fazakerley, Daniel J., Junutula, Jagath R., Vali, Shireen, James, David E., Stöckli, Jacqueline
Published in The Journal of biological chemistry (24.02.2012)
Published in The Journal of biological chemistry (24.02.2012)
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Epigenetic derepression converts PPARγ into a druggable target in triple-negative and endocrine-resistant breast cancers
Loo, Ser Yue, Syn, Nicholas L., Koh, Angele Pei-Fern, Teng, Janet Cheng-Fei, Deivasigamani, Amudha, Tan, Tuan Zea, Thike, Aye Aye, Vali, Shireen, Kapoor, Shweta, Wang, Xiaoyuan, Wang, Jiong Wei, Tan, Puay Hoon, Yip, George W., Sethi, Gautam, Huang, Ruby Yun-Ju, Hui, Kam Man, Wang, Lingzhi, Goh, Boon Cher, Kumar, Alan Prem
Published in Cell death discovery (27.09.2021)
Published in Cell death discovery (27.09.2021)
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Cell genomics and immunosuppressive biomarker expression influence PD-L1 immunotherapy treatment responses in HNSCC - a computational study
Bates, Amber M., BS, Lanzel, Emily, DDS, MS, Qian, Fang, PhD, Abbasi, Taher, ME, MBA, Vali, Shireen, PhD, Brogden, Kim A., PhD
Published in Oral surgery, oral medicine, oral pathology and oral radiology (01.08.2017)
Published in Oral surgery, oral medicine, oral pathology and oral radiology (01.08.2017)
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Journal Article
Celecoxib inhibits MDR1 expression through COX-2-dependent mechanism in human hepatocellular carcinoma (HepG2) cell line
Roy, Karnati R, Reddy, Gorla V, Maitreyi, Leela, Agarwal, Smita, Achari, Chandrani, Vali, Shireen, Reddanna, Pallu
Published in Cancer chemotherapy and pharmacology (01.04.2010)
Published in Cancer chemotherapy and pharmacology (01.04.2010)
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Correction to: Genomics of NSCLC patients both affirm PD-L1 expression and predict their clinical responses to anti-PD-1 immunotherapy
Brogden, Kim A, Parashar, Deepak, Hallier, Andrea R, Braun, Terry, Qian, Fang, Rizvi, Naiyer A, Bossler, Aaron D, Milhem, Mohammed M, Chan, Timothy A, Abbasi, Taher, Vali, Shireen
Published in BMC cancer (12.04.2018)
Published in BMC cancer (12.04.2018)
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C-Phycocyanin inhibits 2-acetylaminofluorene-induced expression of MDR1 in mouse macrophage cells: ROS mediated pathway determined via combination of experimental and In silico analysis
Roy, Karnati R., Arunasree, Kalle M., Dhoot, Amit, Aparna, Rachamallu, Reddy, Gorla Venkateswara, Vali, Shireen, Reddanna, Pallu
Published in Archives of biochemistry and biophysics (15.03.2007)
Published in Archives of biochemistry and biophysics (15.03.2007)
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A computer simulation of progesterone and Cox2 inhibitor treatment for preterm labor
Equils, Ozlem, Nambiar, Priya, Hobel, Calvin J, Smith, Roger, Simmons, Charles F, Vali, Shireen
Published in PloS one (27.01.2010)
Published in PloS one (27.01.2010)
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A kinetic platform for in silico modeling of the metabolic dynamics in Escherichia coli
Barve, Aditya, Gupta, Anvita, Solapure, Suresh M, Kumar, Ansu, Ramachandran, Vasanthi, Seshadri, Kothandaraman, Vali, Shireen, Datta, Santanu
Published in Advances and applications in bioinformatics and chemistry (2010)
Published in Advances and applications in bioinformatics and chemistry (2010)
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Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3
Subramaniam, Aruljothi, Shanmugam, Muthu K, Ong, Tina H, Li, Feng, Perumal, Ekambaram, Chen, Luxi, Vali, Shireen, Abbasi, Taher, Kapoor, Shweta, Ahn, Kwang Seok, Kumar, Alan Prem, Hui, Kam M, Sethi, Gautam
Published in British journal of pharmacology (01.10.2013)
Published in British journal of pharmacology (01.10.2013)
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β-caryophyllene oxide inhibits constitutive and inducible STAT3 signaling pathway through induction of the SHP-1 protein tyrosine phosphatase
Kim, Chulwon, Cho, Somi K., Kapoor, Shweta, Kumar, Ansu, Vali, Shireen, Abbasi, Taher, Kim, Sung-Hoon, Sethi, Gautam, Ahn, Kwang Seok
Published in Molecular carcinogenesis (01.10.2014)
Published in Molecular carcinogenesis (01.10.2014)
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Journal Article
Diosgenin attenuates tumor growth and metastasis in transgenic prostate cancer mouse model by negatively regulating both NF-κB/STAT3 signaling cascades
Sikka, Sakshi, Shanmugam, Muthu K., Siveen, Kodappully Sivaraman, Ong, Tina H., Yang, Min Hee, Lee, Jong Hyun, Rajendran, Peramaiyan, Chinnathambi, Arunachalam, Alharbi, Sulaiman Ali, Alahmadi, Tahani Awad, Vali, Shireen, Kumar, Alan Prem, Sethi, Gautam, Wang, Lingzhi, Hui, Kam Man, Ahn, Kwang Seok
Published in European journal of pharmacology (05.09.2021)
Published in European journal of pharmacology (05.09.2021)
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A feedforward relationship between active Rac1 and phosphorylated Bcl-2 is critical for sustaining Bcl-2 phosphorylation and promoting cancer progression
Chong, Stephen Jun Fei, Lai, Jolin Xiao Hui, Qu, Jianhua, Hirpara, Jayshree, Kang, Jia, Swaminathan, Kunchithapadam, Loh, Thomas, Kumar, Ansu, Vali, Shireen, Abbasi, Taher, Pervaiz, Shazib
Published in Cancer letters (10.08.2019)
Published in Cancer letters (10.08.2019)
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Journal Article
Isorhamnetin Inhibits Proliferation and Invasion and Induces Apoptosis through the Modulation of Peroxisome Proliferator-activated Receptor γ Activation Pathway in Gastric Cancer
Ramachandran, Lalitha, Manu, Kanjoormana Aryan, Shanmugam, Muthu K., Li, Feng, Siveen, Kodappully Sivaraman, Vali, Shireen, Kapoor, Shweta, Abbasi, Taher, Surana, Rohit, Smoot, Duane T., Ashktorab, Hassan, Tan, Patrick, Ahn, Kwang Seok, Yap, Chun Wei, Kumar, Alan Prem, Sethi, Gautam
Published in The Journal of biological chemistry (02.11.2012)
Published in The Journal of biological chemistry (02.11.2012)
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Abstract 1843: Computational biology model (CBM) predicts nutrient dependency of cancer patients based on Tumor Genomics: Implication of precision diet in cancer therapy
Vali, Shireen, Abbasi, Taher, Mohapatra, Subrat, Joseph, Vishwas, Agrawal, Ashish Kumar, Tyagi, Anuj, Lunkad, Neelesh, Balla, Ashokraja
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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