Predictive Simulation Based Design and Validation Of Repurposed Novel Therapeutics With Multi-Target Mechanisms For Multiple Myeloma
Doudican, Nicole A, Vali, Shireen, Kapoor, Shweta, Talawdekar, Anay, Sultana, Zeba, Alam, Aftab, Abbasi, Taher, Mazumder, Amitabha
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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Journal Article
Rational Design of a Therapeutic Program for Multiple Myeloma Using a Strategy of Drug Repurposing and Combination Therapy
Doudican, Nicole A, Vali, Shireen, Kapoor, Shweta, Talawdekar, Anay, Abbasi, Taher, Sethi, Gautam, Mazumder, Amitabha
Published in Blood (16.11.2012)
Published in Blood (16.11.2012)
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Journal Article
Aurora Kinase Is a Therapeutic Target in Ibrutinib-Resistant Waldenstrom Macroglobulinemia: In-Silico Target Identification and in-Vitro Validation
Paulus, Aneel, Chitta, Kasyapa S., Akhtar, Sharoon, Yousaf, Hassan, Cogen, Davitte, Vali, Shireen, Kumar, Ansu, Singh, Neeraj Kumar, Abbasi, Taher, Foran, James M., Rivera, Candido E., Sher, Taimur, Roy, Vivek, Ailawadhi, Sikander, Chanan-Khan, Asher Alban
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Journal Article
Predicting Non-Responders to Immunotherapy Treatments through Simulation of NGS Information
Brogden, Kim A., Fischer, Carol L., Bates, Amber M., Lanzel, Emily A., Gomez Hernandez, Maria Paula, Treinen, Christopher N., Recker, Erica N., Nair, Prashant R., Sundara, Karthik, Joseph, Vishwas, Abbasi, Taher, Vali, Shireen
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Journal Article
Abstract 1706: Individualized therapy identified using simulation for bortezomib resistant patient with ex-vivo validation
Doudican, Nicole A., Vali, Shireen, Leon, Annette, Kumar, Ansu, Singh, Neeraj Kumar, Tyagi, Anuj, Kapoor, Shweta, Sultana, Zeba, Abbasi, Taher, Mazumder, Amitabha
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Journal Article
Personalization of cancer treatment using predictive simulation
Doudican, Nicole A, Kumar, Ansu, Singh, Neeraj Kumar, Nair, Prashant R, Lala, Deepak A, Basu, Kabya, Talawdekar, Anay A, Sultana, Zeba, Tiwari, Krishna Kumar, Tyagi, Anuj, Abbasi, Taher, Vali, Shireen, Vij, Ravi, Fiala, Mark, King, Justin, Perle, MaryAnn, Mazumder, Amitabha
Published in Journal of translational medicine (01.02.2015)
Published in Journal of translational medicine (01.02.2015)
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Journal Article
In silico modeling predicts drug sensitivity of patient-derived cancer cells
Pingle, Sandeep C, Sultana, Zeba, Pastorino, Sandra, Jiang, Pengfei, Mukthavaram, Rajesh, Chao, Ying, Bharati, Ila Sri, Nomura, Natsuko, Makale, Milan, Abbasi, Taher, Kapoor, Shweta, Kumar, Ansu, Usmani, Shahabuddin, Agrawal, Ashish, Vali, Shireen, Kesari, Santosh
Published in Journal of translational medicine (21.05.2014)
Published in Journal of translational medicine (21.05.2014)
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Journal Article
Predicting GBM response to targeted therapeutics using simulation with ex vivo validations
Pingle, Sandeep C., Sultana, Zeba, Jiang, Pengfei, Mukthavaram, Rajesh, Chao, Ying, Abbasi, Taher, Kapoor, Shweta, Kumar, Ansu, Usmani, Shahabuddin, Agrawal, Ashish, Vali, Shireen, Kesari, Santosh
Published in Journal of clinical oncology (20.05.2014)
Published in Journal of clinical oncology (20.05.2014)
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Journal Article
Clinical translation pathway for identifying patient-specific drugs based on predictive simulation outcomes with ex vivo validation
Doudican, Nicole Adell, Vali, Shireen, Meredith, Annette, Talawdekar, Anay, Kumar, Ansu, Singh, Neeraj, Tyagi, Anuj, Kapoor, Shweta, Sultana, Zeba, Abbasi, Taher, Mazumder, Amitabha
Published in Journal of clinical oncology (20.05.2014)
Published in Journal of clinical oncology (20.05.2014)
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Journal Article
Abstract 2104: In vitro validation of rationally designed therapeutic based on drug repositioning and combinations
Doudican, Nicole A., Vali, Shireen, Kapoor, Shweta, Talawdekar, Anay, Sultana, Zeba, Abbasi, Taher, Sethi, Gautam, Orlow, Seth J., Mazumder, Amitabha
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Journal Article
Abstract 5215: Computer based “virtual tumor” simulation identifies novel use for existing drugs - implication for personalized cancer therapy
Vali, Shireen, Kapoor, Shweta, Talawdekar, Anay, Kumar, Ansu, Sultana, Zeba, Gishizky, Mikhail L., Fernandes, Pradeep, Abbasi, Taher
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Journal Article
Computational Biological Modeling Identifies PD-(L)1 Immunotherapy Sensitivity Among Molecular Subgroups of KRAS -Mutated Non-Small-Cell Lung Cancer
Padda, Sukhmani K, Aredo, Jacqueline V, Vali, Shireen, Singh, Neeraj K, Vasista, Sumanth M, Kumar, Ansu, Neal, Joel W, Abbasi, Taher, Wakelee, Heather A
Published in JCO precision oncology (01.11.2021)
Published in JCO precision oncology (01.11.2021)
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Journal Article
Ex Vivo Patient-Specific Validation Of Personalized Therapeutic Designed For Multiple Myeloma
Doudican, Nicole A, Vali, Shireen, Kapoor, Shweta, Talawdekar, Anay, Sultana, Zeba, Alam, Aftab, Kumar, Ansu, Singh, Neeraj Kumar, Tyagi, Anuj, Abbasi, Taher, Mazumder, Amitabha
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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Journal Article
PI3K-Alpha Plays A Major Role In Multiple Myeloma and Its Inhibition With BYL917 Decreases Proliferation, Synergizes With Other Therapies and Overcomes Stroma-Induced Resistance
Azab, Feda, Vali, Shireen, Potter, Nicholas, Abraham, Joseph, Muz, Barbara, De La Puente, Pilar, Abbasi, Taher, Vij, Ravi, Azab, Abdel Kareem
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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Journal Article
Defensin DEFB103 bidirectionally regulates chemokine and cytokine responses to a pro-inflammatory stimulus
Harvey, Lauren E., Kohlgraf, Karl G., Mehalick, Leslie A., Raina, Monica, Recker, Erica N., Radhakrishnan, Saumya, Prasad, Samiksha Avinash, Vidva, Robinson, Progulske-Fox, Ann, Cavanaugh, Joseph E., Vali, Shireen, Brogden, Kim A.
Published in Scientific reports (06.02.2013)
Published in Scientific reports (06.02.2013)
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Journal Article
[beta]-caryophyllene oxide inhibits constitutive and inducible STAT3 signaling pathway through induction of the SHP-1 protein tyrosine phosphatase
Kim, Chulwon, Cho, Somi K, Kapoor, Shweta, Kumar, Ansu, Vali, Shireen, Abbasi, Taher, Kim, Sung-Hoon, Sethi, Gautam, Ahn, Kwang Seok
Published in Molecular carcinogenesis (01.10.2014)
Published in Molecular carcinogenesis (01.10.2014)
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Journal Article
Isorhamnetin inhibits proliferation and invasion and induces apoptosis through the modulation of peroxisome proliferator-activated receptor γ activation pathway in gastric cancer
Ramachandran, Lalitha, Manu, Kanjoormana Aryan, Shanmugam, Muthu K., Li, Feng, Siveen, Kodappully Sivaraman, Vali, Shireen, Kapoor, Shweta, Abbasi, Taher, Surana, Rohit, Smoot, Duane T., Ashktorab, Hassan, Tan, Patrick, Ahn, Kwang Seok, Yap, Chun Wei, Kumar, Alan Prem, Sethi, Gautam
Published in The Journal of biological chemistry (28.06.2013)
Published in The Journal of biological chemistry (28.06.2013)
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