AraC-Daunorubicin-Etoposide (ADE) Response Prediction in Pediatric AML Patients Using a Computational Biology Modeling (CBM) Based Precision Medicine Workflow
Cogle, Christopher R., Abbasi, Taher, Singh, Neeraj Kumar, Sauban, Mohammed, Raman, Rahul K, Vidva, Robinson, Tyagi, Anuj, Talawdekar, Anay Ashok, Das, Arko, Kornblau, Steven M., Hoff, Fieke W, Horton, Terzah M., Vali, Shireen
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Azacitidine Response Prediction in MDS Patients with NGS Data Using a Computational Biology Modeling (CBM) Based Clinical Decision Support System
Minarik, Lubomir, Drusbosky, Leylah M., Abbasi, Taher, Vargova, Karina, Kulvait, Vojtech, Jonasova, Anna, Singh, Neeraj Kumar, Ullal, Yashaswini S, Narayanabhatia, Sirisha, Alam, Aktar, Roy, Kunal Ghosh, Choudhary, Ashish, Vali, Shireen, Cogle, Christopher R., Stopka, Tomas
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Computational Modelling of Multiple Myeloma Patient Genomic Signatures to Predict Treatment Outcome
Paulus, Aneel, Jani, Prachi, Ahmed, Salman, Aulakh, Sonikpreet, Manna, Alak, Singh, Neeraj Kumar, Sauban, Mohammed, Husain, Zakir, Kumar, Ansu, Kumari, Pallavi, Tyagi, Anuj, Sher, Taimur, Manochakian, Rami, Roy, Vivek, Abbasi, Taher, Vali, Shireen, Chanan-Khan, Asher A., Ailawadhi, Sikander
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Predicting Response to Dasatinib Using a Computational Model and Its Validation: A Beat AML Project Study
Tyner, Jeffrey W., Druker, Brian J., Tognon, Cristina E., Kurtz, Stephen E, Drusbosky, Leylah M., Sahu, Diwyanshu, Vidva, Robinson, Kapoor, Shweta, Azam, Humera, Kumar, Rajeev, Chickdipatti, Padmagiri G, Raveendaran, Nithya T, Gopi, Reshma P, Abbasi, Taher, Vali, Shireen, Cogle, Christopher R.
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Predictive Analysis on Prognostic Impact of Monosomy 7 in AML and Identified Therapy Options for This Cohort
Vali, Shireen, Cogle, Christopher R., Arora, Neeraj, Shekhar, Krishnan, Chandy, Mammen, Sengar, Manju, Jain, Hasmukh, Chinnaswamy, Girish, Singh, Neeraj Kumar, Usmani, Shahabuddin, Pampana, Anusha, Shyamasundar, Vijayashree P, Sikora, Huzaifa, Kumar, Ansu, Abbasi, Taher, Radhakrishnan, Vivek S
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Journal Article
Molecular architecture simulation and reverse engineering techniques to uncover clinically applicable novel therapeutic targets in B-lymphoma cells
Paulus, Aneel, Akhtar, Sharoon, Kumar, Ansu, Singh, Neeraj, Vali, Shireen, Abbasi, Taher, Ailawadhi, Sikander, Chanan-Khan, Asher
Published in Journal of clinical oncology (20.05.2016)
Published in Journal of clinical oncology (20.05.2016)
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Journal Article
Computational Models Accurately Predict Multi-Cell Biomarker Profiles in Inflammation and Cancer
Fischer, Carol L., Bates, Amber M., Lanzel, Emily A., Guthmiller, Janet M., Johnson, Georgia K., Singh, Neeraj Kumar, Kumar, Ansu, Vidva, Robinson, Abbasi, Taher, Vali, Shireen, Xie, Xian Jin, Zeng, Erliang, Brogden, Kim A.
Published in Scientific reports (26.07.2019)
Published in Scientific reports (26.07.2019)
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Journal Article
Overexpression of Bcl-2 induces STAT-3 activation via an increase in mitochondrial superoxide
Kang, Jia, Chong, Stephen Jun Fei, Ooi, Vignette Zi Qi, Vali, Shireen, Kumar, Ansu, Kapoor, Shweta, Abbasi, Taher, Hirpara, Jayshree L, Loh, Thomas, Goh, Boon Cher, Pervaiz, Shazib
Published in Oncotarget (27.10.2015)
Published in Oncotarget (27.10.2015)
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Journal Article
Abstract 4285: Genomics-driven clustering of disease-related biomarkers identifies therapeutic options in myelodysplastic syndromes (MDS)
Drusbosky, Leylah M., Hawkins, Kimberly E., Meacham, Amy, Wise, Elizabeth, Singh, Neeraj Kumar, Kumar, Chandan, Vasista, Sumanth M., Suseela, Rakhi P., Abbasi, Taher, Vali, Shireen, Tohyama, Kaoru, Albitar, Maher, Sayeski, Peter P., Cogle, Christopher R.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Elastin sequences trigger transient proinflammatory responses by human dermal fibroblasts
Almine, Jessica F, Wise, Steven G, Hiob, Matti, Singh, Neeraj Kumar, Tiwari, Krishna Kumar, Vali, Shireen, Abbasi, Taher, Weiss, Anthony S
Published in The FASEB journal (01.09.2013)
Published in The FASEB journal (01.09.2013)
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Journal Article
Predicting response to BET inhibitors using computational modeling: A BEAT AML project study
Drusbosky, Leylah M., Vidva, Robinson, Gera, Saji, Lakshminarayana, Anjanasree V., Shyamasundar, Vijayashree P., Agrawal, Ashish Kumar, Talawdekar, Anay, Abbasi, Taher, Vali, Shireen, Tognon, Cristina E., Kurtz, Stephen E., Tyner, Jeffrey W., McWeeney, Shannon K., Druker, Brian J., Cogle, Christopher R.
Published in Leukemia research (01.02.2019)
Published in Leukemia research (01.02.2019)
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Journal Article
Human beta defensin 3 alters matrix metalloproteinase production in human dendritic cells exposed to Porphyromonas gingivalis hemagglutinin B
Raina, Monica, Bates, Amber M, Fischer, Carol L, Progulske-Fox, Ann, Abbasi, Taher, Vali, Shireen, Brogden, Kim A
Published in Journal of periodontology (1970) (01.03.2018)
Published in Journal of periodontology (1970) (01.03.2018)
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Journal Article
Use of Genomic Information to Predict Treatment Response in Multiple Myeloma Patients By Computational Mapping of Protein Network Disturbances
Drusbosky, Leylah, Fiala, Mark A, King, Justin A, Vij, Ravi, Vali, Shireen, Abbasi, Taher, Kumar Singh, Neeraj, Kumar, Ansu, Gera, Saji, Cogle, Christopher R.
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
A Genomic Predictive Signature for Rigosertib in Lower Risk MDS Derived By Integrating Clinical Response, Mechanism of Action Data and Simulation
Fruchtman, Steven M., Ali, Abdullah Mahmood, Petrone, Michael E., Zbyszewski, Patrick Simon, Hoffman, Benjamin, Vali, Shireen, Singh, Neeraj Kumar, Usmani, Shahabuddin, Grover, Himanshu, Abbasi, Taher, Raza, Azra
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
A Genomic Rule Predicting HMA Treatment Response in MDS Identified By Protein Network Mapping and Validated By Clinical Trial Simulation
Drusbosky, Leylah, Kumar Singh, Neeraj, Tiwari, Pranav, Vali, Shireen, Abbasi, Taher, Sarkaria, Sarbjit, Lorant, Adam, Burns, Satin, Bejar, Rafael, Cogle, Christopher R.
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
Predicting Response to CDK4/6 Inhibitors and Combinations Using a Computational Biology Model and Its Validation: A Beat AML Project Study
Drusbosky, Leylah M., Turcotte, Madeleine, Castillo, Paul, Vidva, Robinson, Gera, Saji, Sauban, Mohammed, Bhargav, Priyanka, Deep, Punya, Kapoor, Shweta, Abbasi, Taher, Vali, Shireen, Tognon, Cristina E., Kurtz, Stephen E, Tyner, Jeffrey W., Druker, Brian J., Cogle, Christopher R.
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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Journal Article
Predicting Response to BET Inhibitors Using a Computational Model and Its Validation: A Beat AML Project Study
Drusbosky, Leylah M., Vidva, Robinson, Gera, Saji, Lakshminarayana, Anjanasree V., Shyamasundar, Vijayashree P., Agrawal, Ashish Kumar, Talawdekar, Anay, Abbasi, Taher, Vali, Shireen, Tognon, Cristina E., Kurtz, Stephen E, Tyner, Jeffrey W., Druker, Brian J., Cogle, Christopher R.
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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Journal Article
Personalized Therapy Design for Early T-Cell Precursor Acute Lymphoblastic Leukemia (ETP-ALL) Using Computational Biology Modeling with in Vitro Validation
Turcotte, Madeleine, Bosse, Raphael Charles, Hawkins, Kimberly E., Meacham, Amy, Vijay, Vindhya, Chinnaswamy, Girish, Sengar, Manju, Kumar, Ansu, K, Shwetha, Kamath, Anisha, Nair, Anjana T., Raju, Karthik S., Abbasi, Taher, Vali, Shireen, Cogle, Christopher R., Drusbosky, Leylah M.
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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Journal Article
Computational Modeling of Protein Networks Predicts Treatment Outcomes in Multiple Myeloma (MM)
Drusbosky, Leylah M., Murthy, Hemant S., Leather, Helen L., Grover, Himanshu, Narvekar, Yugandhara, Kumari, Pallavi, Narayanabhatia, Sirisha, Bhowmick, Priyanka, Abbasi, Taher, Vali, Shireen, Zhang, Qing, Usmani, Saad Z, Cogle, Christopher R.
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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Journal Article